ZA921985B - Anti-cancer compounds. - Google Patents

Anti-cancer compounds.

Info

Publication number
ZA921985B
ZA921985B ZA921985A ZA921985A ZA921985B ZA 921985 B ZA921985 B ZA 921985B ZA 921985 A ZA921985 A ZA 921985A ZA 921985 A ZA921985 A ZA 921985A ZA 921985 B ZA921985 B ZA 921985B
Authority
ZA
South Africa
Prior art keywords
cancer compounds
cancer
compounds
Prior art date
Application number
ZA921985A
Other languages
English (en)
Inventor
Graham Michael Fraser Bisset
Ann Lesley Jackmann
Duncan Ian Jodrell
Original Assignee
British Tech Group
Ici Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by British Tech Group, Ici Plc filed Critical British Tech Group
Publication of ZA921985B publication Critical patent/ZA921985B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
    • C07D239/72—Quinazolines; Hydrogenated quinazolines
    • C07D239/95—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in positions 2 and 4
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
    • C07D239/72—Quinazolines; Hydrogenated quinazolines
    • C07D239/86—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in position 4
    • C07D239/88—Oxygen atoms
    • C07D239/90—Oxygen atoms with acyclic radicals attached in position 2 or 3

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
ZA921985A 1991-03-19 1992-03-18 Anti-cancer compounds. ZA921985B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB919105771A GB9105771D0 (en) 1991-03-19 1991-03-19 Anti-cancer compounds

Publications (1)

Publication Number Publication Date
ZA921985B true ZA921985B (en) 1993-09-20

Family

ID=10691801

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA921985A ZA921985B (en) 1991-03-19 1992-03-18 Anti-cancer compounds.

Country Status (18)

Country Link
US (1) US5444061A (pl)
EP (1) EP0509643A1 (pl)
JP (1) JPH06505974A (pl)
AU (1) AU655970B2 (pl)
CA (1) CA2106583A1 (pl)
CZ (1) CZ195393A3 (pl)
FI (1) FI934106A7 (pl)
GB (2) GB9105771D0 (pl)
HU (1) HUT67177A (pl)
IE (1) IE920853A1 (pl)
IL (1) IL101281A0 (pl)
MX (1) MX9201183A (pl)
NO (1) NO933341L (pl)
NZ (1) NZ242023A (pl)
SK (1) SK100993A3 (pl)
TW (1) TW203608B (pl)
WO (1) WO1992016512A1 (pl)
ZA (1) ZA921985B (pl)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9205907D0 (en) * 1992-03-18 1992-04-29 Cancer Res Inst Royal Anti-cancer compounds
GB9223352D0 (en) * 1992-11-06 1992-12-23 Ici Plc Tricyclic compounds
GB9408936D0 (en) * 1994-05-05 1994-06-22 Cancer Res Inst Anti-cancer compounds
IL123164A (en) * 1995-08-30 2001-03-19 Searle & Co Meta-guanidine urea thiourea or azacyclic amino benzoic acid derivatives and pharmaceutical compositions containing them
GB9904275D0 (en) 1999-02-24 1999-04-21 Cancer Res Campaign Tech Anti-cancer compounds
US7671200B2 (en) 1999-10-27 2010-03-02 Cytokinetics, Inc. Quinazolinone KSP inhibitors
US6545004B1 (en) * 1999-10-27 2003-04-08 Cytokinetics, Inc. Methods and compositions utilizing quinazolinones
US7230000B1 (en) 1999-10-27 2007-06-12 Cytokinetics, Incorporated Methods and compositions utilizing quinazolinones
JP2005529076A (ja) * 2002-02-15 2005-09-29 サイトキネティクス・インコーポレーテッド キナゾリノンの合成
RU2004135554A (ru) * 2002-05-09 2006-01-20 Цитокинетикс, Инк. (Us) Пиримидиноны, композиции на их основе и способы их использования
EP1553931A4 (en) 2002-05-09 2006-08-30 Cytokinetics Inc COMPOUNDS, COMPOSITIONS AND METHODS
EP1513820A4 (en) * 2002-05-23 2006-09-13 Cytokinetics Inc COMPOUNDS, COMPOSITIONS AND METHODS
CA2489367A1 (en) * 2002-06-14 2003-12-24 Cytokinetics, Inc. Compounds, compositions, and methods
US20030236430A1 (en) * 2002-06-21 2003-12-25 Allen David Robert Preparation of protected amino acids
EP1537089A4 (en) 2002-07-23 2008-04-16 Cytokinetics Inc CONNECTIONS, COMPOSITIONS AND PROCEDURES
WO2004018058A2 (en) * 2002-08-21 2004-03-04 Cytokinetics, Inc. Compounds, compositions, and methods
WO2004034972A2 (en) * 2002-09-30 2004-04-29 Cytokinetics, Inc. Compounds, compositions, and methods
WO2005041888A2 (en) * 2003-11-03 2005-05-12 Cytokinetics, Inc. Pyrimidin-4-one compounds, compositions and methods
JP2007510660A (ja) * 2003-11-07 2007-04-26 サイトキネティクス・インコーポレーテッド 化合物、組成物及び方法
EP1692112A4 (en) * 2003-12-08 2008-09-24 Cytokinetics Inc COMPOUNDS, COMPOSITIONS, AND METHODS
JP5693950B2 (ja) 2007-04-11 2015-04-01 メルク エ カンパニー １８ｆ標識葉酸
KR102431436B1 (ko) 2014-08-29 2022-08-10 테스 파마 에스.알.엘. α-아미노-β-카복시뮤콘산 세미알데히드 데카복실라제의 억제제
WO2020051424A1 (en) 2018-09-07 2020-03-12 Pic Therapeutics Eif4e inhibitors and uses thereof
TW202146393A (zh) 2020-03-03 2021-12-16 美商皮克醫療公司 Eif4e抑制劑及其用途
US12157732B2 (en) 2021-08-25 2024-12-03 PIC Therapeutics, Inc. eIF4E inhibitors and uses thereof
CA3229560A1 (en) 2021-08-25 2023-03-02 Christopher L. Vandeusen Eif4e inhibitors and uses thereof

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3069468D1 (en) * 1979-12-19 1984-11-22 Nat Res Dev Quinazoline derivatives, processes for their preparation, compositions containing them and their use as anti-cancer agents
GB8513754D0 (en) * 1985-05-31 1985-07-03 Jones T R Anti-cancer quinazoline derivatives
US4746659A (en) * 1985-12-30 1988-05-24 Sri International Diastereomers of 10-alkyl-10-deazaminopterins and process for preparing the same
US5187167A (en) * 1986-03-27 1993-02-16 Imperial Chemical Industries Plc Pharmaceutical compositions comprising quinazolin-4-one derivatives
GB8607683D0 (en) * 1986-03-27 1986-04-30 Ici Plc Anti-tumor agents
GB8625019D0 (en) * 1986-10-18 1986-11-19 Wellcome Found Compounds
GB8707053D0 (en) * 1987-03-25 1987-04-29 Ici Plc Anti-tumour agents
US4767761A (en) * 1987-11-04 1988-08-30 Dana-Farber Cancer Institute, Inc. Ornithine derivatives and their use as methotrexate-resistant cell inhibitors
GB8727737D0 (en) * 1987-11-26 1987-12-31 Ici Plc Antitumour agents
GB8809978D0 (en) * 1988-04-27 1988-06-02 Ici Plc Anti-tumour agents
US5252573A (en) * 1988-12-15 1993-10-12 Imperial Chemical Industries Plc Anti-tumor agents
GB8829296D0 (en) * 1988-12-15 1989-01-25 Ici Plc Anti-tumour compounds
US4996207A (en) * 1990-01-18 1991-02-26 Nair Madhavan G Three new non-polyglutamatable deazaaminopterins
DE69111891T2 (de) * 1990-05-17 1996-04-04 Smith & Nephew United Inc Elektrisch leitender und adstringierender Film sowie filmbildende Zusammensetzung zur Verwendung auf der Haut.
ZA913730B (en) * 1990-05-30 1992-02-26 Ici Plc Anti-tumor compounds

Also Published As

Publication number Publication date
CZ195393A3 (en) 1994-07-13
EP0509643A1 (en) 1992-10-21
IE920853A1 (en) 1992-09-23
GB9205906D0 (en) 1992-04-29
JPH06505974A (ja) 1994-07-07
WO1992016512A1 (en) 1992-10-01
MX9201183A (es) 1994-06-30
AU655970B2 (en) 1995-01-19
US5444061A (en) 1995-08-22
FI934106A0 (fi) 1993-09-20
CA2106583A1 (en) 1992-09-20
NO933341L (no) 1993-11-18
HUT67177A (en) 1995-02-28
TW203608B (pl) 1993-04-11
GB2253849B (en) 1995-01-18
SK100993A3 (en) 1994-08-10
IL101281A0 (en) 1992-11-15
NO933341D0 (no) 1993-09-20
FI934106A7 (fi) 1993-11-18
GB9105771D0 (en) 1991-05-01
GB2253849A (en) 1992-09-23
NZ242023A (en) 1993-12-23
AU1371692A (en) 1992-10-21
HU9302636D0 (en) 1993-12-28

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