ZA921005B - Imidazopyridine PAF/H 1 antagonists. - Google Patents

Imidazopyridine PAF/H 1 antagonists.

Info

Publication number
ZA921005B
ZA921005B ZA921005A ZA921005A ZA921005B ZA 921005 B ZA921005 B ZA 921005B ZA 921005 A ZA921005 A ZA 921005A ZA 921005 A ZA921005 A ZA 921005A ZA 921005 B ZA921005 B ZA 921005B
Authority
ZA
South Africa
Prior art keywords
pct
paf
antagonists
sec
imidazopyridine
Prior art date
Application number
ZA921005A
Other languages
English (en)
Inventor
David Alker
Robert John Bass
Kelvin Cooper
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of ZA921005B publication Critical patent/ZA921005B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Dermatology (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Steroid Compounds (AREA)
  • Prostheses (AREA)
  • Cosmetics (AREA)
ZA921005A 1991-02-13 1992-02-12 Imidazopyridine PAF/H 1 antagonists. ZA921005B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB919102997A GB9102997D0 (en) 1991-02-13 1991-02-13 Therapeutic agents

Publications (1)

Publication Number Publication Date
ZA921005B true ZA921005B (en) 1993-08-12

Family

ID=10689943

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA921005A ZA921005B (en) 1991-02-13 1992-02-12 Imidazopyridine PAF/H 1 antagonists.

Country Status (29)

Country Link
US (1) US5358953A (cs)
EP (1) EP0572425B1 (cs)
JP (1) JP2506541B2 (cs)
KR (1) KR970005302B1 (cs)
CN (1) CN1040326C (cs)
AT (1) ATE109482T1 (cs)
AU (1) AU650322B2 (cs)
BR (1) BR9205615A (cs)
CA (1) CA2099381C (cs)
CZ (1) CZ280504B6 (cs)
DE (1) DE69200304T2 (cs)
DK (1) DK0572425T3 (cs)
EG (1) EG20085A (cs)
ES (1) ES2059212T3 (cs)
FI (1) FI933531A7 (cs)
GB (1) GB9102997D0 (cs)
HU (2) HUT65947A (cs)
IE (1) IE65125B1 (cs)
IL (1) IL100887A (cs)
MX (1) MX9200589A (cs)
MY (1) MY108437A (cs)
NO (1) NO300592B1 (cs)
NZ (1) NZ241597A (cs)
PL (1) PL169304B1 (cs)
RU (1) RU2114845C1 (cs)
TW (1) TW227000B (cs)
WO (1) WO1992014734A1 (cs)
YU (1) YU48238B (cs)
ZA (1) ZA921005B (cs)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2042421B1 (es) * 1992-05-22 1994-08-01 Uriach & Cia Sa J Procedimiento para la obtencion de la 8-cloro-11-*1-*(5-metil-3-piridil)metil*-4-piperidiliden*-6,11-dihidro-5h-benzo*5,6*ciclohepta*1,2-b*piridina.
WO1996005201A1 (en) * 1994-08-10 1996-02-22 British Biotech Pharmaceuticals Limited Imidazopyridine derivatives as dual histamine (h1) and platelet activating factor (paf) antagonists
ES2087038B1 (es) * 1994-11-07 1997-03-16 Uriach & Cia Sa J Nuevas piperidinas con actividad antagonista del paf.
US5567711A (en) * 1995-04-19 1996-10-22 Abbott Laboratories Indole-3-carbonyl and indole-3-sulfonyl derivatives as platelet activating factor antagonists
GB9508748D0 (en) * 1995-04-28 1995-06-14 British Biotech Pharm Benzimidazole derivatives
JPH11510180A (ja) * 1995-08-05 1999-09-07 ブリティッシュ バイオテック ファーマシューティカルズ リミテッド イミダゾピリジン誘導体
SE9801526D0 (sv) * 1998-04-29 1998-04-29 Astra Ab New compounds
PT1311269E (pt) 2000-08-04 2012-05-10 Dmi Biosciences Inc Método de utilização de dicetopiperazinas e composição que contém as mesmas
HUE031620T2 (en) 2003-05-15 2017-07-28 Ampio Pharmaceuticals Inc Treatment of T-cell mediated diseases
US7687515B2 (en) * 2006-01-17 2010-03-30 N.V. Organon 6-phenyl-1H-imidazo[4,5-c]pyridine-4-carbonitrile derivatives
JP5096500B2 (ja) 2008-01-30 2012-12-12 日本臓器製薬株式会社 ピペリジン誘導体
JP5856843B2 (ja) 2008-05-27 2016-02-10 アンピオ ファーマシューティカルズ，インコーポレイテッド ジケトピペラジンを用いた医薬組成物
JP5978296B2 (ja) * 2011-06-28 2016-08-24 フジアン・ミンドン・レジュヴネイション・ファーマスーティカル・カンパニー・リミテッド 抗アレルギ性ベンゾシクロヘプタチオフェン誘導体
EP2765968A4 (en) 2011-10-10 2015-01-21 Ampio Pharmaceuticals Inc IMPLANTABLE MEDICINE PRODUCTS WITH INCREASED IMMUNO TOLERANCE AND PROCESSING AND IMPLANTATION METHODS
CN103841987B (zh) 2011-10-10 2015-06-17 安皮奥制药股份有限公司 退行性关节病的治疗
HK1198812A1 (en) * 2011-10-28 2015-06-12 Ampio Pharmaceuticals, Inc. Treatment of rhinitis
CA2906864A1 (en) 2013-03-15 2014-09-18 Ampio Pharmaceuticals, Inc. Compositions for the mobilization, homing, expansion and differentiation of stem cells and methods of using the same
CN106604915A (zh) 2014-08-18 2017-04-26 安皮奥制药股份有限公司 关节病症的治疗
EP3310375A4 (en) 2015-06-22 2019-02-20 Ampio Pharmaceuticals, Inc. USE OF LOW-MOLECULAR FRACTIONS OF HUMAN SERUMALBUMINE IN THE TREATMENT OF ILLNESSES
CN113880801A (zh) * 2020-07-03 2022-01-04 合肥医工医药股份有限公司 一类三环化合物、其制备方法及其医药用途

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL132137C (cs) * 1963-04-24
JPH03503889A (ja) * 1988-03-15 1991-08-29 ジー．ディー．サール　アンド　カンパニー ＰＡＦ拮抗剤としての１Ｈ／３Ｈ‐［４‐（Ｎ，Ｎ‐ジシクロアルキル／分枝アルキルカルボキサミド）‐ベンジル］イミダゾ［４，５‐ｃ］ピリジン類
ATE141599T1 (de) * 1988-04-28 1996-09-15 Schering Corp Kondensierte polyzyklische verbindungen, zusammenstellungen, verfahren zur herstellung und deren anwendung als paf-antagonistische, antihistaminische und/oder anti-inflammatorische agenzien
US5250681A (en) * 1988-06-02 1993-10-05 Ajinomoto Co., Inc. Piperidine derivatives and hypotensives containing the same
US5114919A (en) * 1990-02-26 1992-05-19 Merck & Co., Inc. Adjuncts in cancer chemotherapy
JPH0678340B2 (ja) * 1990-05-09 1994-10-05 フアイザー・インコーポレイテツド 喘息、関節炎および関連疾患の治療におけるアザベンジミダゾール

Also Published As

Publication number Publication date
JPH06504992A (ja) 1994-06-09
IL100887A (en) 1996-01-19
DE69200304T2 (de) 1994-12-08
CZ280504B6 (cs) 1996-02-14
NO932889D0 (no) 1993-08-13
EP0572425A1 (en) 1993-12-08
EG20085A (en) 1997-05-31
US5358953A (en) 1994-10-25
DE69200304D1 (de) 1994-09-08
GB9102997D0 (en) 1991-03-27
ES2059212T3 (es) 1994-11-01
MX9200589A (es) 1992-10-01
MY108437A (en) 1996-09-30
IL100887A0 (en) 1992-11-15
AU1168392A (en) 1992-09-15
TW227000B (cs) 1994-07-21
FI933531A0 (fi) 1993-08-10
IE65125B1 (en) 1995-10-04
YU14392A (sh) 1994-11-15
JP2506541B2 (ja) 1996-06-12
EP0572425B1 (en) 1994-08-03
FI933531L (fi) 1993-08-10
NO300592B1 (no) 1997-06-23
AU650322B2 (en) 1994-06-16
KR970005302B1 (ko) 1997-04-15
HU211202A9 (en) 1995-11-28
CA2099381C (en) 1996-07-09
CN1040326C (zh) 1998-10-21
CA2099381A1 (en) 1992-08-14
HU9302327D0 (en) 1993-10-28
IE920449A1 (en) 1992-08-12
CN1064275A (zh) 1992-09-09
WO1992014734A1 (en) 1992-09-03
YU48238B (sh) 1997-08-22
CS42592A3 (en) 1992-09-16
FI933531A7 (fi) 1993-08-10
NZ241597A (en) 1993-04-28
RU2114845C1 (ru) 1998-07-10
ATE109482T1 (de) 1994-08-15
PL169304B1 (pl) 1996-06-28
BR9205615A (pt) 1994-05-17
DK0572425T3 (da) 1994-09-12
NO932889L (no) 1993-08-13
HUT65947A (en) 1994-08-29

Similar Documents

Publication Publication Date Title
ZA921005B (en) Imidazopyridine PAF/H 1 antagonists.
YU48426B (sh) Novi supstituisani pirazolilpirazoli, postupak njihovog dobijanja, medjuproizvodi za njihovo dobijanje i primena kao sredstava sa herbicidnim delovanjem
ES2162061T3 (es) Derivados de piperidina como antagonistas de la neuroquinina.
YU84791A (sh) Biciklicni 1-aza-cikloalkalni
BG105513A (en) Substituted benzopyran analogs for the treatment of inflammation
ES2167371T3 (es) Derivados de 1h-3-aril-pirrolidin-2,4-diona espirociclicos substituidos.
PE20050080A1 (es) Antagonistas del receptor opioide
MXPA02011417A (es) 1-aminoalquil-lactamas sustituidas y su uso como antagonistas de receptores muscarinicos.
RU93054165A (ru) Производные имидазопиридина, способ их получения, фармацевтическая композиция, способ лечения
MXPA02011418A (es) 1-aminoalquil-lactamas sustituidas y su uso como antagonistas del receptor muscarinico.
FI922341A0 (fi) Piperidin- och pyrrolidinderivat.
UA41350C2 (uk) Похідна морфоліну або її фармацевтично прийнятна сіль та фармацевтична композиція на її основі
ATE64373T1 (de) Muscarin-rezeptor-antagonisten.
YU4393A (sr) Supstituisani heksahidroazepinoni i tetrahidrobenzazepinoni
ES2095995T3 (es) Procedimiento para la obtencion de 2,2-difluorbenzo(1,3)dioxol-carbaldehidos y nuevos productos intermedios.
PT1018512E (pt) Novos derivados basicos de benzo¬e|isoindol-1-onas e pirrolo¬3,4-c|quinolin-1-onas com actividade antagonista de 5ht3 a sua preparacao e o seu uso terapeutico
MX9606654A (es) Derivados de alaquildiamina substituida y su uso como antagonistas de taquicinina.
ATE62131T1 (de) Pharmazeutische zusammenstellung fuer die prophylaxe oder behandlung von tierhaltungsketose.
FI973558L (fi) Menetelmä terapeuttisesti käytt¦kelpoisten 2-metyyli-imidatsoÄ4,5-cÜpyrid-1-yylijohdannaisten valmistamiseksi
PT100223A (pt) Processo para a preparacao de imidazopiridinas antagonistas de paf/h1
FI900650A0 (fi) Kalciumantagonister.
DE69526106D1 (de) Pyridazinochinolinverbindungen
ES2084547B1 (es) Antagonistas benzopiranicos y relacionados de leucotrieno b4.
NL7609616A (en) (5)-Amino sulphonyl-benzene-(1,3)-dioxamic acids and esters - inhibitors of histamine release, useful e.g. in asthma treatment
ITMI920806A1 (it) Fontanile pluriuso