DE69001794D1 - Phenothiazinderivate, ihre herstellung und sie enthaltende pharmazeutische zusammensetzungen. - Google Patents

Phenothiazinderivate, ihre herstellung und sie enthaltende pharmazeutische zusammensetzungen.

Info

Publication number
DE69001794D1
DE69001794D1 DE9090402602T DE69001794T DE69001794D1 DE 69001794 D1 DE69001794 D1 DE 69001794D1 DE 9090402602 T DE9090402602 T DE 9090402602T DE 69001794 T DE69001794 T DE 69001794T DE 69001794 D1 DE69001794 D1 DE 69001794D1
Authority
DE
Germany
Prior art keywords
alkyl
optionally substituted
denotes
general formula
cycloalkyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE9090402602T
Other languages
English (en)
Other versions
DE69001794T2 (de
Inventor
Claude Garret
Claude Guyon
Bernard Plau
Gerard Taurand
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Rhone Poulenc Sante SA
Original Assignee
Rhone Poulenc Sante SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rhone Poulenc Sante SA filed Critical Rhone Poulenc Sante SA
Publication of DE69001794D1 publication Critical patent/DE69001794D1/de
Application granted granted Critical
Publication of DE69001794T2 publication Critical patent/DE69001794T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D279/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one sulfur atom as the only ring hetero atoms
    • C07D279/10—1,4-Thiazines; Hydrogenated 1,4-thiazines
    • C07D279/14—1,4-Thiazines; Hydrogenated 1,4-thiazines condensed with carbocyclic rings or ring systems
    • C07D279/18—[b, e]-condensed with two six-membered rings
    • C07D279/22—[b, e]-condensed with two six-membered rings with carbon atoms directly attached to the ring nitrogen atom
    • C07D279/24—[b, e]-condensed with two six-membered rings with carbon atoms directly attached to the ring nitrogen atom with hydrocarbon radicals, substituted by amino radicals, attached to the ring nitrogen atom
    • C07D279/28—[b, e]-condensed with two six-membered rings with carbon atoms directly attached to the ring nitrogen atom with hydrocarbon radicals, substituted by amino radicals, attached to the ring nitrogen atom with other substituents attached to the ring system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Neurosurgery (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pain & Pain Management (AREA)
  • Anesthesiology (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Plural Heterocyclic Compounds (AREA)
DE90402602T 1989-09-21 1990-09-20 Phenothiazinderivate, ihre Herstellung und sie enthaltende pharmazeutische Zusammensetzungen. Expired - Fee Related DE69001794T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8912403A FR2652084B1 (fr) 1989-09-21 1989-09-21 Nouveaux derives de la phenothiazine, leur preparation et les compositions pharmaceutiques qui les contiennent.

Publications (2)

Publication Number Publication Date
DE69001794D1 true DE69001794D1 (de) 1993-07-08
DE69001794T2 DE69001794T2 (de) 1993-09-30

Family

ID=9385726

Family Applications (1)

Application Number Title Priority Date Filing Date
DE90402602T Expired - Fee Related DE69001794T2 (de) 1989-09-21 1990-09-20 Phenothiazinderivate, ihre Herstellung und sie enthaltende pharmazeutische Zusammensetzungen.

Country Status (9)

Country Link
US (1) US5321026A (de)
EP (1) EP0419360B1 (de)
JP (1) JPH03120261A (de)
AT (1) ATE90087T1 (de)
CA (1) CA2025930A1 (de)
DE (1) DE69001794T2 (de)
DK (1) DK0419360T3 (de)
ES (1) ES2055371T3 (de)
FR (1) FR2652084B1 (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2689013B1 (fr) * 1992-03-30 1995-05-05 Rhone Poulenc Rorer Sa Nouvelle application thérapeutique des dérivés de la phénothiazine.
FR2720940A1 (fr) * 1994-06-13 1995-12-15 Rhone Poulenc Rorer Sa Application du (+)-N-propyl [(pyrrolidinyl-1)-1 propyl-2]-10 phénothiazinecarboxamide comme antidépresseur.
US6284279B1 (en) 1999-12-03 2001-09-04 Avecia, Inc. Phenothiazine in prill form and method for making the same
DE10032137B4 (de) * 2000-07-01 2009-04-02 Allessachemie Gmbh Verfahren zur Herstellung von Phenothiazin-Granulat mit verbesserten Eigenschaften

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2956996A (en) * 1960-10-18 Alkylated phenotfflazenecarboxamede
GB860330A (en) * 1958-04-23 1961-02-01 Rhone Poulenc Sa Improvements in or relating to phenthiazine derivatives
US3112310A (en) * 1962-01-15 1963-11-26 Searle & Co 10-alkylaminoalkylphenothiazine-2-carboxamides
FR2632520B1 (fr) * 1988-06-10 1990-09-14 Rhone Poulenc Sante Derives de la phenothiazine analgesiques
FR2632521B1 (fr) * 1988-06-10 1990-09-14 Rhone Poulenc Sante Nouveaux derives de la phenothiazine, leur preparation et les compositions pharmaceutiques qui les contiennent
FR2632522B1 (fr) * 1988-06-10 1990-09-14 Rhone Poulenc Sante Nouveaux derives de la phenothiazine, leur preparation et les compositions qui les contiennent

Also Published As

Publication number Publication date
DE69001794T2 (de) 1993-09-30
ATE90087T1 (de) 1993-06-15
FR2652084A1 (fr) 1991-03-22
CA2025930A1 (fr) 1991-03-22
EP0419360A1 (de) 1991-03-27
ES2055371T3 (es) 1994-08-16
EP0419360B1 (de) 1993-06-02
DK0419360T3 (da) 1993-08-16
FR2652084B1 (fr) 1991-10-31
US5321026A (en) 1994-06-14
JPH03120261A (ja) 1991-05-22

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee