ZA919078B - New tricyclic compounds. - Google Patents

New tricyclic compounds.

Info

Publication number
ZA919078B
ZA919078B ZA919078A ZA919078A ZA919078B ZA 919078 B ZA919078 B ZA 919078B ZA 919078 A ZA919078 A ZA 919078A ZA 919078 A ZA919078 A ZA 919078A ZA 919078 B ZA919078 B ZA 919078B
Authority
ZA
South Africa
Prior art keywords
tricyclic compounds
new tricyclic
new
compounds
tricyclic
Prior art date
Application number
ZA919078A
Other languages
English (en)
Inventor
Jacob Berger
Robin Douglas Clark
Original Assignee
Systex Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Systex Inc filed Critical Systex Inc
Publication of ZA919078B publication Critical patent/ZA919078B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/06—Antimigraine agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • Hospice & Palliative Care (AREA)
  • Otolaryngology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
ZA919078A 1990-11-16 1991-11-15 New tricyclic compounds. ZA919078B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/614,326 US5189041A (en) 1990-11-16 1990-11-16 Tricyclic 5-ht3 receptor antagonists

Publications (1)

Publication Number Publication Date
ZA919078B true ZA919078B (en) 1993-05-17

Family

ID=24460766

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA919078A ZA919078B (en) 1990-11-16 1991-11-15 New tricyclic compounds.

Country Status (17)

Country Link
US (1) US5189041A (fr)
EP (1) EP0485962A3 (fr)
JP (1) JPH04283587A (fr)
KR (1) KR920009828A (fr)
AU (1) AU8785291A (fr)
CA (1) CA2055680A1 (fr)
FI (1) FI915400A (fr)
HU (1) HUT59406A (fr)
IE (1) IE913987A1 (fr)
IL (1) IL100061A0 (fr)
IT (1) IT1250049B (fr)
MX (1) MX9102076A (fr)
NO (1) NO914490L (fr)
PL (1) PL292419A1 (fr)
PT (1) PT99518A (fr)
TW (1) TW208007B (fr)
ZA (1) ZA919078B (fr)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ236225A (en) * 1989-11-28 1992-09-25 Syntex Inc Azabicyclic-substituted isoquinoline derivatives, intermediates and pharmaceutical compositions
US5852014A (en) * 1992-03-12 1998-12-22 Smithkline Beecham P.L.C. Condensed indole derivatives as 5HT4 -receptor antagonists
AP401A (en) * 1992-03-12 1995-08-29 Smithkline Beecham Plc Condensed indole derivatives as 5H4-receptor antagonists.
MX9305947A (es) * 1992-09-29 1994-06-30 Smithkline Beecham Plc Compuestos antagonistas del receptor 5-ht4, procedimiento para su preparacion y composiciones farmaceuticas que las contienen.
EP0623582B1 (fr) * 1993-04-27 1998-01-07 Solvay Fluor und Derivate GmbH Procédé de préparation d'esters d'acides carboxyliques à partir d'halogénures d'acides carboxyliques et d'alcools
US6489355B2 (en) * 1993-12-01 2002-12-03 Eli Lilly And Company Methods of inhibiting the effects of amyloidogenic proteins
US5723103A (en) * 1994-12-09 1998-03-03 Vanderbilt University Substituted benzamides and radioligand analogs and methods of use
IT1303123B1 (it) * 1998-10-13 2000-10-30 Rotta Research Lab Derivati basici di benz(e)isoindol-1-oni e pirrolo(3,4-c)chinolin-1-oni ad attivita' 5ht3 antagonista, loro preparazione ed
JP2004502642A (ja) * 2000-02-11 2004-01-29 ブリストル−マイヤーズ　スクイブ　カンパニー カンナビノイドレセプターモジュレーター、それらの製造方法、および呼吸系および非呼吸系疾患の処置のためのカンナビノイドレセプターモジュレーターの使用
JP2003533482A (ja) * 2000-05-18 2003-11-11 グラクソ グループ リミテッド 機能性消化不良の治療方法
AR036040A1 (es) 2001-06-12 2004-08-04 Upjohn Co Compuestos de heteroarilo multiciclicos sustituidos con quinuclidinas y composiciones farmaceuticas que los contienen
AR036041A1 (es) 2001-06-12 2004-08-04 Upjohn Co Compuestos aromaticos heterociclicos sustituidos con quinuclidina y composiciones farmaceuticas que los contienen
BR0214016A (pt) 2001-11-09 2004-10-13 Upjohn Co Compostos azabicìclico-fenil-fundido heterocìclicos e seu uso como ligandos alfa 7 nachr
DE10164139A1 (de) 2001-12-27 2003-07-10 Bayer Ag 2-Heteroarylcarbonsäureamide
DE10234424A1 (de) * 2002-07-29 2004-02-12 Bayer Ag Benzothiophen-, Benzofuran- und Indolharnstoffe
TWI355936B (en) 2003-02-18 2012-01-11 Helsinn Healthcare Sa Uses of palonosetron hydrochloride
ITMI20031467A1 (it) * 2003-07-18 2005-01-19 Acraf Farmaco attivo nel dolore neuropatico
PL2540297T3 (pl) 2008-11-19 2015-12-31 Forum Pharmaceuticals Inc Leczenie zaburzeń funkcji poznawczych(R)-7-chloro-N-(chinuklidyn-3-ylo)benzo[b]tiofeno-2-karboksyamidem i jego farmaceutyczne dopuszczalnymi solami
US9145396B2 (en) 2008-12-01 2015-09-29 Targacept, Inc. Synthesis and novel salt forms of (R)-5-((E)-2-pyrrolidin-3ylvinyl)pyrimidine
PL3029039T3 (pl) 2010-05-17 2018-04-30 Forum Pharmaceuticals Inc. Formulacje farmaceutyczne zawierające postacie krystaliczne jednowodnego chlorowodorku (R)-7-chloro-N-(chinuklidyn-3-ylo)benzo[b]tiofeno-2-karboksyamidu
AU2013259871A1 (en) 2012-05-08 2014-11-20 Forum Pharmaceuticals Inc. Methods of maintaining, treating or improving cognitive function

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2121394A1 (fr) * 1971-01-08 1972-08-25 Anvar Procédé d'obtention de dérivés d'acides indole carboxyliques et produits préparables par ce procédé.
JPS5337696A (en) * 1976-08-26 1978-04-06 Omnium Chimique Sa Hexahydrocantinonee6 derivative
FR2475394A1 (fr) * 1980-02-12 1981-08-14 Synthelabo Compositions pharmaceutiques contenant l'hexahydro-1, 2, 3, 3a, 4, 5, 6h indolo (3, 2, 1 - d. e) (1, 5) naphtyridinone - 6
FI74707C (fi) * 1982-06-29 1988-03-10 Sandoz Ag Foerfarande foer framstaellning av terapeutiskt anvaendbara alkylenoeverbryggade piperidylestrar eller -amider av bicykliska karboxylsyror.
GB8623142D0 (en) * 1986-09-26 1986-10-29 Beecham Group Plc Compounds
DE3777805D1 (de) * 1986-11-21 1992-04-30 Glaxo Group Ltd Arzneimittel zur behandlung oder vorbeugung des entzugssyndromes.
PH25493A (en) * 1987-09-03 1991-07-24 Glaxo Group Ltd 2,3,4,5-tetrahydro-2-£(imidazol-(or-5)-yl)methyl-ih-pyrido£4,3-b|indol-1-ones , derivatives having 5-ht antagonist activity 3
DE3810552A1 (de) * 1988-03-29 1989-10-19 Sandoz Ag Ester und amide von indol-, benzo(b)thiopen-, benzo(b)furancarbonsaeuren oder 4-amino-2-methoxy-benzolsaeuren mit n-heterocyclischen oder n-heterobicyclischen alkoholen oder aminen, verfahren zu deren herstellung sie enthaltende pharmazeutische zusammensetzungen sowie applikator zur verabreichung derselben
JPH02167280A (ja) * 1988-08-15 1990-06-27 Glaxo Group Ltd ラクタム誘導体
EP0377238A1 (fr) * 1988-12-22 1990-07-11 Duphar International Research B.V Indolo(3,2-c)-lactames annelés
GB8904551D0 (en) * 1989-02-28 1989-04-12 Glaxo Group Ltd Chemical compounds
KR900013959A (ko) * 1989-03-13 1990-10-22 원본미기재 γ-카르블린 또는 그들의 제약학적으로 허용 가능한 산부가염 및/또는 수화물, 및 그들로 구성되는 제약학적 조성물
JPH02290878A (ja) * 1989-04-28 1990-11-30 Ono Pharmaceut Co Ltd ベンゾチエノ（フロ）ピリジン誘導体

Also Published As

Publication number Publication date
AU8785291A (en) 1992-05-21
ITTO910865A0 (it) 1991-11-12
TW208007B (fr) 1993-06-21
JPH04283587A (ja) 1992-10-08
NO914490L (no) 1992-05-18
EP0485962A3 (en) 1992-07-29
US5189041A (en) 1993-02-23
PT99518A (pt) 1992-09-30
HU913579D0 (en) 1992-01-28
PL292419A1 (en) 1993-04-05
IL100061A0 (en) 1992-08-18
MX9102076A (es) 1992-07-08
FI915400A (fi) 1992-05-17
IT1250049B (it) 1995-03-30
NO914490D0 (no) 1991-11-15
FI915400A0 (fi) 1991-11-15
KR920009828A (ko) 1992-06-25
CA2055680A1 (fr) 1992-05-17
EP0485962A2 (fr) 1992-05-20
IE913987A1 (en) 1992-05-20
HUT59406A (en) 1992-05-28
ITTO910865A1 (it) 1992-05-17

Similar Documents

Publication Publication Date Title
DE69107059D1 (en) Sigma-delta-modulator.
ZA92908B (en) Compounds.
EP0565582A4 (fr) Nouveaux medicaments anti-inflammatoires suppresseurs de cytokine.
AR244753A1 (es) Azocolorantes.
AP9100313A0 (en) Compounds
ZA919078B (en) New tricyclic compounds.
EP0633771A4 (en) Compounds.
DE69111595D1 (en) Squarylium- und crokonyliumfarbstoffe.
DE69104185D1 (en) Luftreservoir.
DE69112211D1 (en) Luftreinigungsvorrichtung.
ZA929517B (en) Compounds.
AP9100314A0 (en) Compounds
DE69106281D1 (en) Phenanthrenderivat.
ZA916617B (en) Tricyclic compounds
DE69102644D1 (en) Demodulationsreferenzsignalquelle.
DE69110012D1 (en) Linienerkennungsverfahren.
DE69114491D1 (en) Olefincopolymere.
GB9013016D0 (en) Compounds
GB2244704B (en) Substituted benzene compounds
AU8628791A (en) Substituted tricyclic compounds
ZA913605B (en) Novel tricyclic compounds
DE59100097D1 (en) Plungerzylinder.
GR3017775T3 (en) Phenoxy-heterocyclic compounds.
GB9002834D0 (en) Compounds
DE69100445D1 (en) Thiosulfatfixierloesungen.