ZA918134B - Heterocyclic compounds - Google Patents

Heterocyclic compounds

Info

Publication number
ZA918134B
ZA918134B ZA918134A ZA918134A ZA918134B ZA 918134 B ZA918134 B ZA 918134B ZA 918134 A ZA918134 A ZA 918134A ZA 918134 A ZA918134 A ZA 918134A ZA 918134 B ZA918134 B ZA 918134B
Authority
ZA
South Africa
Prior art keywords
alkyl
phenyl
cycloalkyl
pharmaceutically
hydrogen
Prior art date
Application number
ZA918134A
Other languages
English (en)
Inventor
Rodney Brian Hargreaves
Brian Hargreaves Rodney
Original Assignee
Ici Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ici Plc filed Critical Ici Plc
Publication of ZA918134B publication Critical patent/ZA918134B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Detergent Compositions (AREA)
  • Air Bags (AREA)
  • Separation Using Semi-Permeable Membranes (AREA)
ZA918134A 1990-10-18 1991-10-11 Heterocyclic compounds ZA918134B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB909022644A GB9022644D0 (en) 1990-10-18 1990-10-18 Heterocyclic compounds

Publications (1)

Publication Number Publication Date
ZA918134B true ZA918134B (en) 1992-07-29

Family

ID=10683928

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA918134A ZA918134B (en) 1990-10-18 1991-10-11 Heterocyclic compounds

Country Status (14)

Country Link
US (1) US5328910A (de)
EP (1) EP0482804B1 (de)
JP (1) JPH04273878A (de)
AT (1) ATE148119T1 (de)
AU (1) AU8581391A (de)
CA (1) CA2053626A1 (de)
DE (1) DE69124335D1 (de)
FI (1) FI914910A (de)
GB (1) GB9022644D0 (de)
IE (1) IE913598A1 (de)
IL (1) IL99709A0 (de)
NZ (1) NZ240180A (de)
PT (1) PT99264A (de)
ZA (1) ZA918134B (de)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK0674641T3 (da) 1992-12-17 1999-09-27 Pfizer Pyrrolopyrimidiner som CRF-antagonister
IL112249A (en) 1994-01-25 2001-11-25 Warner Lambert Co Pharmaceutical compositions containing di and tricyclic pyrimidine derivatives for inhibiting tyrosine kinases of the epidermal growth factor receptor family and some new such compounds
IL112248A0 (en) 1994-01-25 1995-03-30 Warner Lambert Co Tricyclic heteroaromatic compounds and pharmaceutical compositions containing them
TW574214B (en) * 1994-06-08 2004-02-01 Pfizer Corticotropin releasing factor antagonists
EP0766684A4 (de) * 1994-06-09 1997-07-16 Smithkline Beecham Corp Endothelin-rezeptor antagonisten
US6956047B1 (en) 1995-06-06 2005-10-18 Pfizer Inc. Corticotropin releasing factor antagonists
US6403599B1 (en) 1995-11-08 2002-06-11 Pfizer Inc Corticotropin releasing factor antagonists
US7067664B1 (en) 1995-06-06 2006-06-27 Pfizer Inc. Corticotropin releasing factor antagonists
DE69830409T2 (de) * 1997-08-05 2006-01-26 Pfizer Products Inc., Groton 4-aminopyrrole[3,2-d]pyrimidine als neuropeptid rezeptor antagonisten
AR033295A1 (es) 2001-04-30 2003-12-10 Glaxo Group Ltd Compuestos biciclicos de pirimidina, proceso para su obtencion, uso de los mismos para la preparacion de una composicion farmaceutica y dicha composicion farmaceutica
EP1395591B1 (de) 2001-06-12 2008-06-04 Glaxo Group Limited Corticotropinfreisetzungsfaktor antagonisten
DE10163991A1 (de) * 2001-12-24 2003-07-03 Merck Patent Gmbh Pyrrolo-pyrimidine
US7115525B2 (en) * 2004-09-02 2006-10-03 Micron Technology, Inc. Method for integrated circuit fabrication using pitch multiplication
EP3694866A1 (de) 2017-10-13 2020-08-19 Imperial College Of Science, Technology And Medicine Map4k4-inhibitoren

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB815833A (en) * 1956-09-26 1959-07-01 Boots Pure Drug Co Ltd Phenanthridine compounds
BE492034A (de) * 1948-11-05
US2748124A (en) * 1954-05-06 1956-05-29 Searle & Co 1-(4-anilino-2-pyrimidino)-3-alkylureas
DE1241832B (de) * 1963-02-23 1967-06-08 Hoechst Ag Verfahren zur Herstellung von Pyrimidiniumverbindungen
DE1445740A1 (de) * 1963-09-04 1968-11-28 Bayer Ag Verfahren zur Herstellung von Bispyrimidinium-Verbindungen
DE2818676A1 (de) * 1978-04-27 1979-11-08 Troponwerke Gmbh & Co Kg Substituierte 5,6-dimethylpyrrolo 2,3-d pyrimidine, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel
US4339453A (en) * 1979-07-23 1982-07-13 Merck & Co., Inc. Antimicrobial aminopyrimidinium salts
DE3145287A1 (de) * 1981-11-14 1983-05-19 Troponwerke GmbH & Co KG, 5000 Köln Pyrrolo (2.3-d)pyrimidine, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel
US4503050A (en) * 1983-06-02 1985-03-05 Riker Laboratories, Inc. Substituted imidazo[1,2-c]pyrimidines
US4725600A (en) * 1984-07-13 1988-02-16 Fujisawa Pharmaceutical Co., Ltd. Pyrimidine compounds having activity as a cardiotonic anti-hypertensive cerebrovascular vasodilator and anti-platelet aggregation agent
IL88507A (en) * 1987-12-03 1993-02-21 Smithkline Beckman Intercredit 2,4-diaminoquinazolines, process for their preparation and pharmaceutical compositions comprising them
ZA902280B (en) * 1989-03-29 1990-12-28 Merrell Dow Pharma Selective adenosine receptor agents
IE63502B1 (en) * 1989-04-21 1995-05-03 Zeneca Ltd Aminopyrimidine derivatives useful for treating cardiovascular disorders
GB8929022D0 (en) * 1989-12-22 1990-02-28 Ici Plc Diazine derivatives

Also Published As

Publication number Publication date
IE913598A1 (en) 1992-04-22
FI914910A0 (fi) 1991-10-17
EP0482804A1 (de) 1992-04-29
CA2053626A1 (en) 1992-04-19
EP0482804B1 (de) 1997-01-22
GB9022644D0 (en) 1990-11-28
ATE148119T1 (de) 1997-02-15
JPH04273878A (ja) 1992-09-30
NZ240180A (en) 1993-12-23
AU8581391A (en) 1992-07-02
US5328910A (en) 1994-07-12
PT99264A (pt) 1992-08-31
DE69124335D1 (de) 1997-03-06
IL99709A0 (en) 1992-08-18
FI914910A (fi) 1992-04-19

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