ZA915905B - Cyclopentane derivatives,process for their production and their pharmaceutical use - Google Patents

Cyclopentane derivatives,process for their production and their pharmaceutical use

Info

Publication number
ZA915905B
ZA915905B ZA915905A ZA915905A ZA915905B ZA 915905 B ZA915905 B ZA 915905B ZA 915905 A ZA915905 A ZA 915905A ZA 915905 A ZA915905 A ZA 915905A ZA 915905 B ZA915905 B ZA 915905B
Authority
ZA
South Africa
Prior art keywords
pharmaceutical use
production
cyclopentane derivatives
formula
cyclopentane
Prior art date
Application number
ZA915905A
Other languages
English (en)
Inventor
Ulrich Klar
Klar Ulrich
Hartmut Rehwinkel
Rehwinkel Hartmut
Helmut Vorbruggen
Vorbruggen Helmut
Karl-Heinz Thierauch
Thierauch Karl-Heinz
Peter Verhallen
Verhallen Peter
Original Assignee
Schering Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Ag filed Critical Schering Ag
Publication of ZA915905B publication Critical patent/ZA915905B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/36—Sulfur atoms

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
ZA915905A 1990-07-27 1991-07-26 Cyclopentane derivatives,process for their production and their pharmaceutical use ZA915905B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4024347A DE4024347A1 (de) 1990-07-27 1990-07-27 Cyclopentanderivate, verfahren zu ihrer herstellung und ihre pharmazeutische verwendung

Publications (1)

Publication Number Publication Date
ZA915905B true ZA915905B (en) 1992-04-29

Family

ID=6411402

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA915905A ZA915905B (en) 1990-07-27 1991-07-26 Cyclopentane derivatives,process for their production and their pharmaceutical use

Country Status (13)

Country Link
EP (1) EP0541594B1 (pt)
JP (1) JPH06502390A (pt)
AT (1) ATE122036T1 (pt)
AU (1) AU8221291A (pt)
CA (1) CA2088161A1 (pt)
DE (3) DE4024347A1 (pt)
DK (1) DK0541594T3 (pt)
ES (1) ES2074721T3 (pt)
IE (1) IE67507B1 (pt)
IL (1) IL98970A0 (pt)
PT (1) PT98464B (pt)
WO (1) WO1992002495A1 (pt)
ZA (1) ZA915905B (pt)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4036140A1 (de) * 1990-11-09 1992-05-14 Schering Ag 9-halogen-11ss-hydroxy-prostaglandinderivate, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel
AU687906B2 (en) * 1993-12-15 1998-03-05 Alcon Laboratories, Inc. Use of certain prostaglandin analogues to treat glaucoma and ocular hypertension
US5977173A (en) * 1997-09-09 1999-11-02 Wos; John August Aromatic C16 -C20 -substituted tetrahydro prostaglandins useful as FP agonists
WO1999012898A1 (en) * 1997-09-09 1999-03-18 The Procter & Gamble Company Aromatic c16-c20-substituted tetrahydro prostaglandins useful as fp agonists
ATE310721T1 (de) * 1997-09-09 2005-12-15 Aromatische c16-c20-substituierte tetrahydro- prostaglandinen verwendbar wie fp agoniste
WO1999047497A2 (en) * 1998-03-13 1999-09-23 Merck Frosst Canada & Co. Carboxylic acids and acylsulfonamides, compositions containing such compounds and methods of treatment
US6242493B1 (en) 1998-03-13 2001-06-05 Merck Frosst Canada & Co. Carboxylic acids and acylsulfonamides, compositions containing such compounds and methods of treatment
EP1159266B1 (en) 1999-03-05 2004-11-03 Duke University C-16 unsaturated fp-selective prostaglandins analogs
US20020013294A1 (en) 2000-03-31 2002-01-31 Delong Mitchell Anthony Cosmetic and pharmaceutical compositions and methods using 2-decarboxy-2-phosphinico derivatives
US20020172693A1 (en) 2000-03-31 2002-11-21 Delong Michell Anthony Compositions and methods for treating hair loss using non-naturally occurring prostaglandins
US7323591B2 (en) * 2006-01-10 2008-01-29 Allergan, Inc. Substituted cyclopentanes or cyclopentanones as therapeutic agents
WO2009140205A2 (en) * 2008-05-15 2009-11-19 Allergan, Inc. Therapeutic substituted cyclopentanes
CN102336754B (zh) * 2010-07-15 2017-04-12 浙江奥翔药业股份有限公司 恩替卡韦的合成方法及其中间体化合物

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1431561A (en) * 1973-01-31 1976-04-07 Ici Ltd Cyclopentane derivatives
IT1053781B (it) * 1974-09-25 1981-10-10 Erba C S P A Ora Farmitalia Omega nor cicloalcil 13.14 deidro prostaglandine
FR2349328A1 (fr) * 1976-04-30 1977-11-25 Roussel Uclaf Nouveaux derives de la 11-desoxy prostaglandine f2, leur procede de preparation et leur application comme medicaments
DE3126924A1 (de) * 1981-07-03 1983-01-20 Schering Ag, 1000 Berlin Und 4619 Bergkamen 9-fluor-prostaglandinderivate, verfahren zur herstellung und verwendung als arzneimittel
DE3325175A1 (de) * 1983-07-08 1985-01-17 Schering AG, 1000 Berlin und 4709 Bergkamen 11-halogen-prostanderivate, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel
DE3510978A1 (de) * 1985-03-22 1986-09-25 Schering AG, Berlin und Bergkamen, 1000 Berlin Neue 9-halogenprostaglandine, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel
EP0299914B2 (de) * 1987-07-17 2003-04-23 Schering Aktiengesellschaft 9-Halogen-(Z)-prostaglandinderivate, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel
DE3923797A1 (de) * 1989-07-14 1991-01-24 Schering Ag 9-fluor-prostaglandin-derivate, verfahren zu ihrer herstellung und ihre pharmazeutische verwendung

Also Published As

Publication number Publication date
IL98970A0 (en) 1992-07-15
ES2074721T3 (es) 1995-09-16
EP0541594B1 (de) 1995-05-03
IE67507B1 (en) 1996-04-03
EP0541594A1 (de) 1993-05-19
WO1992002495A1 (de) 1992-02-20
PT98464A (pt) 1992-05-29
CA2088161A1 (en) 1992-01-28
IE912654A1 (en) 1992-01-29
DE4024347A1 (de) 1992-01-30
DK0541594T3 (da) 1995-10-02
DE59105400D1 (de) 1995-06-08
PT98464B (pt) 1997-10-31
AU8221291A (en) 1992-03-02
JPH06502390A (ja) 1994-03-17
ATE122036T1 (de) 1995-05-15
DE4191848D2 (de) 1993-10-07

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