ES8704148A1 - Un procedimiento para preparar derivados de antraciclina - Google Patents
Un procedimiento para preparar derivados de antraciclinaInfo
- Publication number
- ES8704148A1 ES8704148A1 ES544745A ES544745A ES8704148A1 ES 8704148 A1 ES8704148 A1 ES 8704148A1 ES 544745 A ES544745 A ES 544745A ES 544745 A ES544745 A ES 544745A ES 8704148 A1 ES8704148 A1 ES 8704148A1
- Authority
- ES
- Spain
- Prior art keywords
- medicaments
- same
- production
- pharmaceutical composition
- composition containing
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/20—Carbocyclic rings
- C07H15/24—Condensed ring systems having three or more rings
- C07H15/252—Naphthacene radicals, e.g. daunomycins, adriamycins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/20—Bacteria; Culture media therefor
- C12N1/205—Bacterial isolates
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P19/00—Preparation of compounds containing saccharide radicals
- C12P19/44—Preparation of O-glycosides, e.g. glucosides
- C12P19/56—Preparation of O-glycosides, e.g. glucosides having an oxygen atom of the saccharide radical directly bound to a condensed ring system having three or more carbocyclic rings, e.g. daunomycin, adriamycin
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
- C12R2001/00—Microorganisms ; Processes using microorganisms
- C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
- C12R2001/465—Streptomyces
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicinal Chemistry (AREA)
- Oncology (AREA)
- Pharmacology & Pharmacy (AREA)
- Molecular Biology (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Communicable Diseases (AREA)
- Public Health (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Tropical Medicine & Parasitology (AREA)
- Virology (AREA)
- Biomedical Technology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Saccharide Compounds (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Abstract
PROCEDIMIENTO PARA LA PREPARACION DE DERIVADOS DE ANTRACICLINA, DE FORMULA GENERAL (I), Y SUS SALES DE ADICION DE ACIDO FARACEUTICAMENTE ACEPTABLES. CONSISTE EN CULTIVAR UNA CEPA DEL GENERO STREPTOMYCES CAPAZ DE PRODUCIR COMPUESTOS DE ANTRACICLINA EN UN MEDIO ADECUADO DE CULTIVO BAJO CONDICIONES AEROBIAS, Y EN RECUPERAR SUBSIGUIENTEMENTE LOS COMPUESTOS DE FORMULA GENERAL (I) OBTENIDOS EN EL MEDIO DE CULTIVO. DICHO MEDIO DE CULTIVO COMPRENDE FUENTES NUTRITIVAS DE CARBONO, FUENTES DE NITROGENO Y, OPCIONALMENTE, SALES INORGANICAS O AGENTES ANTIESPUMANTES, A UNA TEMPERATURA COMPRENDIDA ENTRE 20 Y 35 GRADOS. DE APLICACION COMO ANTIBIOTICOS PARA EL CONTROL DEL CANCER.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP59137486A JPS6117597A (ja) | 1984-07-03 | 1984-07-03 | アントラサイクリン化合物 |
Publications (2)
Publication Number | Publication Date |
---|---|
ES8704148A1 true ES8704148A1 (es) | 1987-03-16 |
ES544745A0 ES544745A0 (es) | 1987-03-16 |
Family
ID=15199762
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES544745A Expired ES8704148A1 (es) | 1984-07-03 | 1985-07-01 | Un procedimiento para preparar derivados de antraciclina |
Country Status (9)
Country | Link |
---|---|
EP (1) | EP0167935B1 (es) |
JP (1) | JPS6117597A (es) |
AT (1) | ATE45953T1 (es) |
DE (1) | DE3572668D1 (es) |
DK (1) | DK165747B (es) |
ES (1) | ES8704148A1 (es) |
GR (1) | GR851608B (es) |
HU (1) | HU194942B (es) |
ZA (1) | ZA854979B (es) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE10029433A1 (de) * | 2000-06-15 | 2001-12-20 | Bioleads Gmbh | Rhodomycinon-Derivate |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS6023679B2 (ja) * | 1979-07-13 | 1985-06-08 | メルシャン株式会社 | ロドマイシン群抗生物質とその製造法 |
JPS5982395A (ja) * | 1982-11-02 | 1984-05-12 | Microbial Chem Res Found | アントラサイクリン化合物、その製造法およびその用途 |
DE3323025A1 (de) * | 1983-06-25 | 1985-01-10 | Hoechst Ag, 6230 Frankfurt | Anthracyclin-derivate, ein mikrobiologisches verfahren zu ihrer herstellung und ihre verwendung als cytostatika |
DE3325957A1 (de) * | 1983-07-19 | 1985-02-07 | Hoechst Ag, 6230 Frankfurt | Anthracyclin-derivate, ein verfahren zu ihrer herstellung und ihre verwendung als cytostatika |
-
1984
- 1984-07-03 JP JP59137486A patent/JPS6117597A/ja active Pending
-
1985
- 1985-06-26 EP EP85107940A patent/EP0167935B1/en not_active Expired
- 1985-06-26 HU HU852506A patent/HU194942B/hu not_active IP Right Cessation
- 1985-06-26 AT AT85107940T patent/ATE45953T1/de not_active IP Right Cessation
- 1985-06-26 DE DE8585107940T patent/DE3572668D1/de not_active Expired
- 1985-07-01 GR GR851608A patent/GR851608B/el unknown
- 1985-07-01 ES ES544745A patent/ES8704148A1/es not_active Expired
- 1985-07-02 ZA ZA854979A patent/ZA854979B/xx unknown
- 1985-07-02 DK DK301685A patent/DK165747B/da not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
DK165747B (da) | 1993-01-11 |
EP0167935A3 (en) | 1986-10-08 |
DK301685D0 (da) | 1985-07-02 |
HU194942B (en) | 1988-03-28 |
HUT41441A (en) | 1987-04-28 |
DE3572668D1 (en) | 1989-10-05 |
ZA854979B (en) | 1986-02-26 |
EP0167935A2 (en) | 1986-01-15 |
DK301685A (da) | 1986-01-04 |
JPS6117597A (ja) | 1986-01-25 |
EP0167935B1 (en) | 1989-08-30 |
ATE45953T1 (de) | 1989-09-15 |
GR851608B (es) | 1985-11-26 |
ES544745A0 (es) | 1987-03-16 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FD1A | Patent lapsed |
Effective date: 20010301 |