US5629020A
(en)
|
1994-04-22 |
1997-05-13 |
Emisphere Technologies, Inc. |
Modified amino acids for drug delivery
|
US6331318B1
(en)
|
1994-09-30 |
2001-12-18 |
Emisphere Technologies Inc. |
Carbon-substituted diketopiperazine delivery systems
|
US5693338A
(en)
|
1994-09-29 |
1997-12-02 |
Emisphere Technologies, Inc. |
Diketopiperazine-based delivery systems
|
US5541155A
(en)
|
1994-04-22 |
1996-07-30 |
Emisphere Technologies, Inc. |
Acids and acid salts and their use in delivery systems
|
US5443841A
(en)
*
|
1992-06-15 |
1995-08-22 |
Emisphere Technologies, Inc. |
Proteinoid microspheres and methods for preparation and use thereof
|
US5451410A
(en)
*
|
1993-04-22 |
1995-09-19 |
Emisphere Technologies, Inc. |
Modified amino acids for encapsulating active agents
|
US6221367B1
(en)
|
1992-06-15 |
2001-04-24 |
Emisphere Technologies, Inc. |
Active agent transport systems
|
US5578323A
(en)
|
1992-06-15 |
1996-11-26 |
Emisphere Technologies, Inc. |
Proteinoid carriers and methods for preparation and use thereof
|
US6099856A
(en)
|
1992-06-15 |
2000-08-08 |
Emisphere Technologies, Inc. |
Active agent transport systems
|
US5447728A
(en)
*
|
1992-06-15 |
1995-09-05 |
Emisphere Technologies, Inc. |
Desferrioxamine oral delivery system
|
US5714167A
(en)
|
1992-06-15 |
1998-02-03 |
Emisphere Technologies, Inc. |
Active agent transport systems
|
JPH05202177A
(ja)
*
|
1991-09-06 |
1993-08-10 |
Teijin Ltd |
生分解性共重合体、及びそれを含有する医薬品組成物
|
GB9211268D0
(en)
*
|
1992-05-28 |
1992-07-15 |
Ici Plc |
Salts of basic peptides with carboxyterminated polyesters
|
US5792451A
(en)
|
1994-03-02 |
1998-08-11 |
Emisphere Technologies, Inc. |
Oral drug delivery compositions and methods
|
US5811127A
(en)
|
1992-06-15 |
1998-09-22 |
Emisphere Technologies, Inc. |
Desferrioxamine oral delivery system
|
FR2693905B1
(fr)
*
|
1992-07-27 |
1994-09-02 |
Rhone Merieux |
Procédé de préparation de microsphères pour la libération prolongée de l'hormone LHRH et ses analogues, microsphères et formulations obtenues.
|
DE69316101T2
(de)
*
|
1992-08-07 |
1998-10-22 |
Takeda Chemical Industries Ltd |
Herstellung von Mikrokapseln, die wasserlösliche Arzneimittel enthalten
|
EP0646000A4
(en)
*
|
1992-11-16 |
1997-05-02 |
Univ Mercer |
COMPOSITIONS CONTAINING MICRO-ENCODED NEUTRALIZING ANTIBODIES.
|
UA61046C2
(en)
|
1992-12-07 |
2003-11-17 |
Takeda Chemical Industries Ltd |
Sustained-release preparation and method for its manufacture
|
TW333456B
(en)
|
1992-12-07 |
1998-06-11 |
Takeda Pharm Ind Co Ltd |
A pharmaceutical composition of sustained-release preparation the invention relates to a pharmaceutical composition of sustained-release preparation which comprises a physiologically active peptide.
|
US5401516A
(en)
|
1992-12-21 |
1995-03-28 |
Emisphere Technologies, Inc. |
Modified hydrolyzed vegetable protein microspheres and methods for preparation and use thereof
|
US5863985A
(en)
*
|
1995-06-29 |
1999-01-26 |
Kinerton Limited |
Ionic molecular conjugates of biodegradable polyesters and bioactive polypeptides
|
RU2146128C1
(ru)
*
|
1993-01-06 |
2000-03-10 |
Кинертон Лимитед |
Ионный конъюгат с длительным периодом высвобождения пептида, способ синтезирования ионного конъюгата, способ синтезирования микрочастиц
|
US6221958B1
(en)
|
1993-01-06 |
2001-04-24 |
Societe De Conseils De Recherches Et D'applications Scientifiques, Sas |
Ionic molecular conjugates of biodegradable polyesters and bioactive polypeptides
|
US5672659A
(en)
*
|
1993-01-06 |
1997-09-30 |
Kinerton Limited |
Ionic molecular conjugates of biodegradable polyesters and bioactive polypeptides
|
ATE204467T1
(de)
|
1993-04-22 |
2001-09-15 |
Emisphere Tech Inc |
Orale darreichungsform
|
US5709861A
(en)
|
1993-04-22 |
1998-01-20 |
Emisphere Technologies, Inc. |
Compositions for the delivery of antigens
|
US5643957A
(en)
|
1993-04-22 |
1997-07-01 |
Emisphere Technologies, Inc. |
Compounds and compositions for delivering active agents
|
US5958457A
(en)
|
1993-04-22 |
1999-09-28 |
Emisphere Technologies, Inc. |
Compositions for the delivery of antigens
|
US6087324A
(en)
*
|
1993-06-24 |
2000-07-11 |
Takeda Chemical Industries, Ltd. |
Sustained-release preparation
|
KR100369764B1
(ko)
*
|
1994-07-20 |
2003-05-22 |
키너톤 리미티드 |
생분해성폴리에스테르및생활성폴리펩티드의이온성분자결합체
|
US5650386A
(en)
|
1995-03-31 |
1997-07-22 |
Emisphere Technologies, Inc. |
Compositions for oral delivery of active agents
|
US5866536A
(en)
|
1995-03-31 |
1999-02-02 |
Emisphere Technologies, Inc. |
Compounds and compositions for delivering active agents
|
US5965121A
(en)
|
1995-03-31 |
1999-10-12 |
Emisphere Technologies, Inc. |
Compounds and compositions for delivering active agents
|
CN1151836C
(zh)
|
1995-03-31 |
2004-06-02 |
艾米斯菲尔技术有限公司 |
用作传送活性剂的化合物和组合物
|
US6001347A
(en)
|
1995-03-31 |
1999-12-14 |
Emisphere Technologies, Inc. |
Compounds and compositions for delivering active agents
|
US6090958A
(en)
|
1995-03-31 |
2000-07-18 |
Emisphere Technologies, Inc. |
Compounds and compositions for delivering active agents
|
US5989539A
(en)
|
1995-03-31 |
1999-11-23 |
Emisphere Technologies, Inc. |
Compounds and compositions for delivering active agents
|
US5820881A
(en)
|
1995-04-28 |
1998-10-13 |
Emisphere Technologies, Inc. |
Microspheres of diamide-dicarboxylic acids
|
US5750147A
(en)
|
1995-06-07 |
1998-05-12 |
Emisphere Technologies, Inc. |
Method of solubilizing and encapsulating itraconazole
|
US6051258A
(en)
|
1995-06-07 |
2000-04-18 |
Emisphere Technologies, Inc. |
Proteinoid emulsions and methods for preparation and use thereof
|
US5824345A
(en)
|
1995-06-07 |
1998-10-20 |
Emisphere Technologies, Inc. |
Fragrances and flavorants
|
US5667806A
(en)
|
1995-06-07 |
1997-09-16 |
Emisphere Technologies, Inc. |
Spray drying method and apparatus
|
EP0835101B1
(en)
|
1995-06-27 |
2004-06-09 |
Takeda Chemical Industries, Ltd. |
Method of producing sustained-release preparation
|
DE19681560T1
(de)
|
1995-09-11 |
1998-08-20 |
Emisphere Tech Inc |
Verfahren zur Herstellung von omega-Aminoalkansäure-Derivaten aus Cycloalkanonen
|
ATE192334T1
(de)
|
1995-11-09 |
2000-05-15 |
Microbiological Res Authority |
Mikroverkapselte dna zur impfung und gentherapie
|
US6270795B1
(en)
|
1995-11-09 |
2001-08-07 |
Microbiological Research Authority |
Method of making microencapsulated DNA for vaccination and gene therapy
|
WO1997047288A1
(en)
|
1996-06-14 |
1997-12-18 |
Emisphere Technologies, Inc. |
Microencapsulated fragrances and method for preparation
|
AU779930B2
(en)
*
|
1996-12-11 |
2005-02-17 |
Praecis Pharmaceuticals Incorporated |
Pharmaceutical formulations for sustained drug delivery
|
US5968895A
(en)
|
1996-12-11 |
1999-10-19 |
Praecis Pharmaceuticals, Inc. |
Pharmaceutical formulations for sustained drug delivery
|
US5783567A
(en)
*
|
1997-01-22 |
1998-07-21 |
Pangaea Pharmaceuticals, Inc. |
Microparticles for delivery of nucleic acid
|
US5990166A
(en)
|
1997-02-07 |
1999-11-23 |
Emisphere Technologies, Inc. |
Compounds and compositions for delivering active agents
|
US5879681A
(en)
|
1997-02-07 |
1999-03-09 |
Emisphere Technolgies Inc. |
Compounds and compositions for delivering active agents
|
US5939381A
(en)
|
1997-02-07 |
1999-08-17 |
Emisphere Technologies, Inc. |
Compounds and compositions for delivering active agents
|
US5876710A
(en)
|
1997-02-07 |
1999-03-02 |
Emisphere Technologies Inc. |
Compounds and compositions for delivering active agents
|
US5804688A
(en)
|
1997-02-07 |
1998-09-08 |
Emisphere Technologies, Inc. |
Compounds and compositions for delivering active agents
|
US6060513A
(en)
|
1997-02-07 |
2000-05-09 |
Emisphere Technologies, Inc. |
Compounds and compositions for delivering active agents
|
US6313088B1
(en)
|
1997-02-07 |
2001-11-06 |
Emisphere Technologies, Inc. |
8-[(2-hydroxy-4-methoxy benzoyl) amino]-octanoic acid compositions for delivering active agents
|
US5863944A
(en)
|
1997-04-30 |
1999-01-26 |
Emisphere Technologies, Inc. |
Compounds and compositions for delivering active agents
|
US5962710A
(en)
|
1997-05-09 |
1999-10-05 |
Emisphere Technologies, Inc. |
Method of preparing salicyloylamino acids
|
US6867181B1
(en)
|
1997-06-02 |
2005-03-15 |
Societe De Conseils De Recherches Et D'applications Scientifiques, S.A.S. |
Ionic molecular conjugates of biodegradable polyesters and bioactive polypeptides
|
DE19723807C2
(de)
*
|
1997-06-06 |
2003-04-24 |
Ferring Gmbh |
Verfahren zur Herstellung von Copolyestern
|
AU8591298A
(en)
*
|
1997-07-25 |
1999-02-16 |
Sdg, Inc. |
Polymer based pharmaceutical compositions for targeted delivery of biologically active agents
|
IL122933A
(en)
*
|
1998-01-14 |
2005-03-20 |
Efrat Biopolymers Ltd |
Polymeric carrier for delivery of a bioactive molecule
|
CN1289255A
(zh)
|
1998-01-29 |
2001-03-28 |
基纳顿有限公司 |
制备可吸收微粒的方法
|
US6406719B1
(en)
|
1998-05-13 |
2002-06-18 |
Microbiological Research Authority |
Encapsulation of bioactive agents
|
GB9810236D0
(en)
|
1998-05-13 |
1998-07-08 |
Microbiological Res Authority |
Improvements relating to encapsulation of bioactive agents
|
AU4697099A
(en)
|
1998-06-18 |
2000-01-05 |
Johns Hopkins University School Of Medicine, The |
Polymers for delivery of nucleic acids
|
US6916490B1
(en)
|
1998-07-23 |
2005-07-12 |
UAB Research Center |
Controlled release of bioactive substances
|
US6884436B2
(en)
*
|
2000-12-22 |
2005-04-26 |
Baxter International Inc. |
Method for preparing submicron particle suspensions
|
US20050048126A1
(en)
|
2000-12-22 |
2005-03-03 |
Barrett Rabinow |
Formulation to render an antimicrobial drug potent against organisms normally considered to be resistant to the drug
|
US8067032B2
(en)
|
2000-12-22 |
2011-11-29 |
Baxter International Inc. |
Method for preparing submicron particles of antineoplastic agents
|
US6951656B2
(en)
|
2000-12-22 |
2005-10-04 |
Baxter International Inc. |
Microprecipitation method for preparing submicron suspensions
|
US9700866B2
(en)
|
2000-12-22 |
2017-07-11 |
Baxter International Inc. |
Surfactant systems for delivery of organic compounds
|
DE60231862D1
(de)
|
2001-02-23 |
2009-05-20 |
Genentech Inc |
Erodierbare polymere zur injektion
|
BR0212833A
(pt)
|
2001-09-26 |
2004-10-13 |
Baxter Int |
Preparação de nanopartìculas de tamanho submìcron através de dispersão e de remoção de solvente ou de fase lìquida
|
US20060003012A9
(en)
|
2001-09-26 |
2006-01-05 |
Sean Brynjelsen |
Preparation of submicron solid particle suspensions by sonication of multiphase systems
|
DE10206517A1
(de)
*
|
2002-02-16 |
2003-09-04 |
Stoess & Co Gelatine |
Depotarzneimittel, Trägermaterialien für Depotarzneimittel und Verfahren zu deren Herstellung
|
KR100405879B1
(ko)
*
|
2002-09-19 |
2003-11-14 |
키너톤 리미티드 |
생분해성 폴리에스테르 및 생활성 폴리펩티드의 이온성분자 결합체
|
US8133505B2
(en)
|
2002-10-31 |
2012-03-13 |
Transpharma Medical Ltd. |
Transdermal delivery system for dried particulate or lyophilized medications
|
IL152574A
(en)
*
|
2002-10-31 |
2009-09-22 |
Transpharma Medical Ltd |
A system for passing through the skin of dry items or dried medicines
|
DK1594517T3
(da)
|
2003-01-28 |
2007-10-29 |
Microbia Inc |
Sammensætninger til behandlingen af gastrointestinale lidelser
|
US7772188B2
(en)
|
2003-01-28 |
2010-08-10 |
Ironwood Pharmaceuticals, Inc. |
Methods and compositions for the treatment of gastrointestinal disorders
|
US7393537B2
(en)
*
|
2003-04-25 |
2008-07-01 |
Allergan, Inc. |
Botulinum toxin for treatment of obsessive compulsive finger biting disorder
|
CN1845938B
(zh)
|
2003-06-30 |
2010-05-26 |
杜门蒂斯有限公司 |
多肽
|
ES2383525T3
(es)
|
2003-11-05 |
2012-06-21 |
Sarcode Bioscience Inc. |
Moduladores de la adhesión celular
|
CA2552677A1
(en)
*
|
2004-01-13 |
2005-07-28 |
Vasogenix Pharmaceuticals, Inc. |
Controlled release cgrp delivery composition for cardiovascular and renal indications
|
TW200538148A
(en)
*
|
2004-01-13 |
2005-12-01 |
Vasogenix Pharmaceuticals Inc |
Methods for treating acute myocardial infarction by administering calcitonin gene related peptide and compositions containing the same
|
US20090023644A1
(en)
*
|
2004-01-13 |
2009-01-22 |
Southard Jeffery L |
Methods of using cgrp for cardiovascular and renal indications
|
EP1711163A2
(en)
*
|
2004-02-05 |
2006-10-18 |
Baxter International Inc. |
Dispersions prepared by use of self-stabilizing agents
|
US7563443B2
(en)
|
2004-09-17 |
2009-07-21 |
Domantis Limited |
Monovalent anti-CD40L antibody polypeptides and compositions thereof
|
WO2006125119A1
(en)
|
2005-05-17 |
2006-11-23 |
Sarcode Corporation |
Compositions and methods for treatment of eye disorders
|
US20070142287A1
(en)
*
|
2005-12-20 |
2007-06-21 |
Biomed Solutions, Llc |
Compositions And Methods For Treatment Of Cancer
|
US20100222875A1
(en)
*
|
2006-08-08 |
2010-09-02 |
Abbott Cardiovascular Systems Inc. |
Method for forming a porous stent coating
|
US8426467B2
(en)
|
2007-05-22 |
2013-04-23 |
Baxter International Inc. |
Colored esmolol concentrate
|
US8722736B2
(en)
|
2007-05-22 |
2014-05-13 |
Baxter International Inc. |
Multi-dose concentrate esmolol with benzyl alcohol
|
CN101772513B
(zh)
|
2007-06-04 |
2013-11-13 |
协同医药品公司 |
有效用于胃肠功能紊乱、炎症、癌症和其他疾病治疗的鸟苷酸环化酶激动剂
|
US8969514B2
(en)
|
2007-06-04 |
2015-03-03 |
Synergy Pharmaceuticals, Inc. |
Agonists of guanylate cyclase useful for the treatment of hypercholesterolemia, atherosclerosis, coronary heart disease, gallstone, obesity and other cardiovascular diseases
|
CA3105972A1
(en)
|
2007-10-19 |
2009-04-30 |
Novartis Ag |
Compositions and methods for treatment of diabetic retinopathy
|
WO2009139817A2
(en)
|
2008-04-15 |
2009-11-19 |
Sarcode Corporation |
Crystalline pharmaceutical and methods of preparation and use thereof
|
EP2328910B1
(en)
|
2008-06-04 |
2014-08-06 |
Synergy Pharmaceuticals Inc. |
Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders
|
EP3241839B1
(en)
|
2008-07-16 |
2019-09-04 |
Bausch Health Ireland Limited |
Agonists of guanylate cyclase useful for the treatment of gastrointestinal, inflammation, cancer and other disorders
|
US8168759B2
(en)
|
2008-07-18 |
2012-05-01 |
Bristol-Myers Squibb Company |
Compositions monovalent for CD28 binding and methods of use
|
WO2011050175A1
(en)
|
2009-10-21 |
2011-04-28 |
Sarcode Corporation |
Crystalline pharmaceutical and methods of preparation and use thereof
|
CA2797133C
(en)
*
|
2010-04-27 |
2019-08-06 |
Zealand Pharma A/S |
Peptide conjugates of glp-1 receptor agonists and gastrin and their use
|
GB201009037D0
(en)
|
2010-05-28 |
2010-07-14 |
Univ Surrey |
Compositions and methods for treating disorders associated with atherosclerotic plaques
|
US8865220B2
(en)
*
|
2010-06-14 |
2014-10-21 |
Kaohsiung Medical University |
Method for controlled release of parathyroid hormone from encapsulated poly(lactic-glycolic)acid microspheres
|
BRPI1003424A2
(pt)
*
|
2010-09-08 |
2013-01-08 |
Univ Rio De Janeiro |
sistema polimÉtrico de confinamento de amilina humana e anÁlogos agonistas, processo e uso; processo de avaliaÇço funcional de amilina liberada
|
US9616097B2
(en)
|
2010-09-15 |
2017-04-11 |
Synergy Pharmaceuticals, Inc. |
Formulations of guanylate cyclase C agonists and methods of use
|
CA3065694A1
(en)
|
2010-11-10 |
2012-05-18 |
Inregen |
Methods of forming injectable formulations for providing regenerative effects to an organ such as a kidney
|
JP6092849B2
(ja)
|
2011-05-04 |
2017-03-08 |
バランス セラピューティックス, インコーポレイテッドBalance Therapeutics, Inc. |
ペンチレンテトラゾール誘導体
|
KR102157608B1
(ko)
|
2012-07-25 |
2020-09-18 |
에스에이알코드 바이오사이언스 인코포레이티드 |
Lfa-1 저해제 및 그의 다형체
|
DK2912165T3
(da)
|
2012-10-24 |
2019-09-16 |
Inregen |
Nyrecellepopulationer og anvendelser deraf
|
WO2014120916A1
(en)
|
2013-02-01 |
2014-08-07 |
Bristol-Myers Squibb Company |
Pegylated domain antibodies monovalent for cd28 binding and methods of use
|
JP6499591B2
(ja)
|
2013-02-25 |
2019-04-10 |
シナジー ファーマシューティカルズ インコーポレイテッド |
結腸洗浄において用いるためのグアニル酸シクラーゼ受容体アゴニスト
|
WO2014151206A1
(en)
|
2013-03-15 |
2014-09-25 |
Synergy Pharmaceuticals Inc. |
Agonists of guanylate cyclase and their uses
|
JP2016514670A
(ja)
|
2013-03-15 |
2016-05-23 |
シナジー ファーマシューティカルズ インコーポレイテッド |
他の薬物と組み合わせたグアニル酸シクラーゼ受容体アゴニスト
|
AU2014331704A1
(en)
|
2013-10-10 |
2016-04-28 |
Synergy Pharmaceuticals, Inc. |
Agonists of guanylate cyclase useful for the treatment of opioid induced dysfunctions
|
EP3402804A1
(en)
|
2016-01-11 |
2018-11-21 |
Synergy Pharmaceuticals Inc. |
Formulations and methods for treating ulcerative colitis
|
KR20210049864A
(ko)
*
|
2018-08-24 |
2021-05-06 |
노쓰 캐롤라이나 스테이트 유니버시티 |
폐루프 인슐린 전달을 위한 포도당 반응성 매트릭스를 갖는 마이크로니들 배열 패치
|
WO2024080308A1
(ja)
*
|
2022-10-12 |
2024-04-18 |
中外製薬株式会社 |
ペプチド、界面活性剤及びポリマーを含む組成物
|