ZA914452B - Heterocyclic anthracyclinone and anthracycline analogs - Google Patents

Heterocyclic anthracyclinone and anthracycline analogs

Info

Publication number
ZA914452B
ZA914452B ZA914452A ZA914452A ZA914452B ZA 914452 B ZA914452 B ZA 914452B ZA 914452 A ZA914452 A ZA 914452A ZA 914452 A ZA914452 A ZA 914452A ZA 914452 B ZA914452 B ZA 914452B
Authority
ZA
South Africa
Prior art keywords
anthracyclinone
heterocyclic
anthracycline analogs
anthracycline
analogs
Prior art date
Application number
ZA914452A
Other languages
English (en)
Inventor
Giorgio Attardo
Attardo Giorgio
Bernard Belleau
Belleau Bernard
Yao Chang Xu
Chang Xu Yao
Jean-Francois Lavallee
Lavallee Jean-Francois
Rabindra N Rej
N Rej Rabindra
Original Assignee
Iaf Biochem Int
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Iaf Biochem Int filed Critical Iaf Biochem Int
Publication of ZA914452B publication Critical patent/ZA914452B/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D335/00Heterocyclic compounds containing six-membered rings having one sulfur atom as the only ring hetero atom
    • C07D335/04Heterocyclic compounds containing six-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D335/06Benzothiopyrans; Hydrogenated benzothiopyrans
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D311/00Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/76Benzo[c]pyrans
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D311/00Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/78Ring systems having three or more relevant rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D319/00Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D319/041,3-Dioxanes; Hydrogenated 1,3-dioxanes
    • C07D319/061,3-Dioxanes; Hydrogenated 1,3-dioxanes not condensed with other rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D327/00Heterocyclic compounds containing rings having oxygen and sulfur atoms as the only ring hetero atoms
    • C07D327/02Heterocyclic compounds containing rings having oxygen and sulfur atoms as the only ring hetero atoms one oxygen atom and one sulfur atom
    • C07D327/06Six-membered rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D333/00Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/50Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D333/72Benzo[c]thiophenes; Hydrogenated benzo[c]thiophenes
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D335/00Heterocyclic compounds containing six-membered rings having one sulfur atom as the only ring hetero atom
    • C07D335/04Heterocyclic compounds containing six-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D407/00Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
    • C07D407/02Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
    • C07D407/04Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20Carbocyclic rings
    • C07H15/24Condensed ring systems having three or more rings
    • C07H15/244Anthraquinone radicals, e.g. sennosides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20Carbocyclic rings
    • C07H15/24Condensed ring systems having three or more rings
    • C07H15/252Naphthacene radicals, e.g. daunomycins, adriamycins
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08Hetero rings containing eight or more ring members, e.g. erythromycins

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Virology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Forms Removed On Construction Sites Or Auxiliary Members Thereof (AREA)
ZA914452A 1990-06-11 1991-06-11 Heterocyclic anthracyclinone and anthracycline analogs ZA914452B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US53610790A 1990-06-11 1990-06-11

Publications (1)

Publication Number Publication Date
ZA914452B true ZA914452B (en) 1992-06-24

Family

ID=24137175

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA914452A ZA914452B (en) 1990-06-11 1991-06-11 Heterocyclic anthracyclinone and anthracycline analogs

Country Status (18)

Country Link
EP (1) EP0533744A1 (fi)
JP (1) JPH06504034A (fi)
CN (1) CN1058781A (fi)
AP (1) AP340A (fi)
AU (1) AU653348B2 (fi)
CA (1) CA2085120A1 (fi)
CS (1) CS178691A3 (fi)
FI (1) FI925611A0 (fi)
HU (1) HU9203720D0 (fi)
IE (1) IE911965A1 (fi)
IL (1) IL98460A0 (fi)
MA (1) MA22178A1 (fi)
NZ (1) NZ238490A (fi)
PL (1) PL297164A1 (fi)
PT (1) PT97931A (fi)
WO (1) WO1991019725A2 (fi)
YU (1) YU103391A (fi)
ZA (1) ZA914452B (fi)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5606037A (en) * 1992-11-09 1997-02-25 Biochem Pharma Inc. Processes antineoplastic heteronaphthoquinones
US5736523A (en) * 1992-11-09 1998-04-07 Biochem Pharma Inc. Antineoplastic heteronapthoquinones
WO1994011382A1 (en) * 1992-11-09 1994-05-26 Biochem Pharma Inc. Antineoplastic heteronaphthoquinones
AU6672794A (en) * 1993-11-05 1995-05-23 Biochem Pharma Inc. Antineoplastic heteronaphthoquinones
IT1271689B (it) * 1994-08-04 1997-06-04 Menarini Farma Ind 8-fluoro-antracicline, loro processi di preparazione e composizioni farmaceutiche che le contengono
KR20210057053A (ko) 2018-08-23 2021-05-20 씨젠 인크. 항-tigit 항체
CN111087377B (zh) * 2020-03-19 2020-06-26 广东省微生物研究所(广东省微生物分析检测中心) 苯并异色满醌类化合物及其制备方法和应用

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6030315B2 (ja) * 1976-06-01 1985-07-16 三井東圧化学株式会社 4−ハロゲノメチルイソクマリン誘導体の製造法
JPS52148088A (en) * 1976-06-01 1977-12-08 Richardson Merrell Inc 111aminoalkylmorphansridinee 111ols
GB2067552B (en) * 1980-01-16 1984-02-29 Erba Farmitalia Anthracyline derivatives
JPS60142976A (ja) * 1983-12-28 1985-07-29 Yoshinori Asakawa イソクマリン誘導体
PH25651A (en) * 1986-05-21 1991-08-21 Duphar Int Res New di, tetrahydroisoquinoline derivatives
JPH01238579A (ja) * 1988-03-18 1989-09-22 Yamanouchi Pharmaceut Co Ltd Y−05460m−a物質及びその製造法
JPH08112310A (ja) * 1994-10-18 1996-05-07 New Oji Paper Co Ltd 使いすておむつ

Also Published As

Publication number Publication date
CS178691A3 (en) 1992-01-15
NZ238490A (en) 1994-03-25
IL98460A0 (en) 1992-07-15
EP0533744A1 (en) 1993-03-31
CA2085120A1 (en) 1991-12-12
JPH06504034A (ja) 1994-05-12
AU8097391A (en) 1992-01-07
FI925611A (fi) 1992-12-10
WO1991019725A2 (en) 1991-12-26
PL297164A1 (fi) 1992-10-05
PT97931A (pt) 1992-03-31
IE911965A1 (en) 1991-12-18
HU9203720D0 (en) 1993-03-29
FI925611A0 (fi) 1992-12-10
MA22178A1 (fr) 1991-12-31
WO1991019725A3 (en) 1992-04-30
AP9100278A0 (en) 1991-07-31
CN1058781A (zh) 1992-02-19
YU103391A (sh) 1994-04-05
AU653348B2 (en) 1994-09-29
AP340A (en) 1994-05-13

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