GB2215332B - New 4-demethyl-4-0-(p-fluorobenzensulfonyl)-anthracycline glycosides - Google Patents

New 4-demethyl-4-0-(p-fluorobenzensulfonyl)-anthracycline glycosides

Info

Publication number
GB2215332B
GB2215332B GB8828830A GB8828830A GB2215332B GB 2215332 B GB2215332 B GB 2215332B GB 8828830 A GB8828830 A GB 8828830A GB 8828830 A GB8828830 A GB 8828830A GB 2215332 B GB2215332 B GB 2215332B
Authority
GB
United Kingdom
Prior art keywords
fluorobenzensulfonyl
demethyl
new
anthracycline glycosides
anthracycline
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
GB8828830A
Other versions
GB2215332A (en
GB8828830D0 (en
Inventor
Michele Caruso
Stefania Stefanelli
Antonino Suarato
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Italia SRL
Original Assignee
Farmitalia Carlo Erba SRL
Carlo Erba SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Farmitalia Carlo Erba SRL, Carlo Erba SpA filed Critical Farmitalia Carlo Erba SRL
Publication of GB8828830D0 publication Critical patent/GB8828830D0/en
Publication of GB2215332A publication Critical patent/GB2215332A/en
Application granted granted Critical
Publication of GB2215332B publication Critical patent/GB2215332B/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/24—Condensed ring systems having three or more rings
    • C07H15/252—Naphthacene radicals, e.g. daunomycins, adriamycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
GB8828830A 1988-02-25 1988-12-09 New 4-demethyl-4-0-(p-fluorobenzensulfonyl)-anthracycline glycosides Expired - Fee Related GB2215332B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB888804429A GB8804429D0 (en) 1988-02-25 1988-02-25 New 4-demethyl-4-0-(fluorobenzensulfonyl)anthracycline glycosides

Publications (3)

Publication Number Publication Date
GB8828830D0 GB8828830D0 (en) 1989-01-18
GB2215332A GB2215332A (en) 1989-09-20
GB2215332B true GB2215332B (en) 1990-10-17

Family

ID=10632363

Family Applications (2)

Application Number Title Priority Date Filing Date
GB888804429A Pending GB8804429D0 (en) 1988-02-25 1988-02-25 New 4-demethyl-4-0-(fluorobenzensulfonyl)anthracycline glycosides
GB8828830A Expired - Fee Related GB2215332B (en) 1988-02-25 1988-12-09 New 4-demethyl-4-0-(p-fluorobenzensulfonyl)-anthracycline glycosides

Family Applications Before (1)

Application Number Title Priority Date Filing Date
GB888804429A Pending GB8804429D0 (en) 1988-02-25 1988-02-25 New 4-demethyl-4-0-(fluorobenzensulfonyl)anthracycline glycosides

Country Status (4)

Country Link
JP (1) JPH01254695A (en)
DE (1) DE3905431A1 (en)
GB (2) GB8804429D0 (en)
IT (1) IT1228453B (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1318532B1 (en) * 2000-05-19 2003-08-27 Antibioticos Spa ANTHRACYCLINIC DERIVATIVES SYNTHESIS PROCEDURE.
US7053191B2 (en) * 2003-05-21 2006-05-30 Solux Corporation Method of preparing 4-R-substituted 4-demethoxydaunorubicin
CN100379749C (en) * 2003-05-21 2008-04-09 獀洛克斯股份有限公司 Method of preparing 4-R-substituted 4-demethoxydaunorubicin
EP2991993B1 (en) 2013-04-29 2018-06-06 Nerviano Medical Sciences S.r.l. Morpholinyl anthracycline derivatives
KR102562864B1 (en) 2014-11-05 2023-08-04 네르비아노 메디칼 사이언시스 에스.알.엘. Functionalized morpholinyl anthracycline derivatives

Also Published As

Publication number Publication date
IT8919523A0 (en) 1989-02-22
GB8804429D0 (en) 1988-03-23
GB2215332A (en) 1989-09-20
IT1228453B (en) 1991-06-19
JPH01254695A (en) 1989-10-11
GB8828830D0 (en) 1989-01-18
DE3905431A1 (en) 1989-09-07

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Legal Events

Date Code Title Description
PCNP Patent ceased through non-payment of renewal fee

Effective date: 19961209