ZA913691B - Isochromane derivatives - Google Patents

Isochromane derivatives

Info

Publication number
ZA913691B
ZA913691B ZA913691A ZA913691A ZA913691B ZA 913691 B ZA913691 B ZA 913691B ZA 913691 A ZA913691 A ZA 913691A ZA 913691 A ZA913691 A ZA 913691A ZA 913691 B ZA913691 B ZA 913691B
Authority
ZA
South Africa
Prior art keywords
alkyl
hydrogen
group
alkoxy
hydroxy
Prior art date
Application number
ZA913691A
Other languages
English (en)
Inventor
Michel Combourieu
Combourieu Michel
Jean-Claude Laigle
Laigle Jean-Claude
Nadine Simbille
Simbille Nadine
Original Assignee
Akzo Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Akzo Nv filed Critical Akzo Nv
Publication of ZA913691B publication Critical patent/ZA913691B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/76—Benzo[c]pyrans
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Cardiology (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Detergent Compositions (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Pyrane Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
ZA913691A 1990-05-25 1991-05-15 Isochromane derivatives ZA913691B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP90401407 1990-05-25

Publications (1)

Publication Number Publication Date
ZA913691B true ZA913691B (en) 1992-02-26

Family

ID=8205714

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA913691A ZA913691B (en) 1990-05-25 1991-05-15 Isochromane derivatives

Country Status (15)

Country Link
EP (1) EP0458387B1 (xx)
JP (1) JPH04253970A (xx)
KR (1) KR910020004A (xx)
AT (1) ATE140001T1 (xx)
AU (1) AU643277B2 (xx)
CA (1) CA2042861A1 (xx)
DE (1) DE69120603T2 (xx)
DK (1) DK0458387T3 (xx)
ES (1) ES2091283T3 (xx)
FI (1) FI912400A (xx)
GR (1) GR3021084T3 (xx)
IE (1) IE73232B1 (xx)
NZ (1) NZ238243A (xx)
PT (1) PT97766B (xx)
ZA (1) ZA913691B (xx)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0737189B1 (en) * 1993-12-28 1999-07-28 PHARMACIA & UPJOHN COMPANY Heterocyclic compounds for the treatment of cns and cardiovascular disorders
US6492375B2 (en) 1998-06-30 2002-12-10 Neuromed Technologies, Inc. Partially saturated calcium channel blockers
US6951862B2 (en) 1998-06-30 2005-10-04 Neuromed Technologies, Inc. Calcium channel blockers comprising two benzhydril moieties
US6943168B2 (en) 1998-06-30 2005-09-13 Neuromed Technologies Inc. Calcium channel inhibitors comprising benzhydril spaced from piperazine
US6011035A (en) 1998-06-30 2000-01-04 Neuromed Technologies Inc. Calcium channel blockers
US6387897B1 (en) 1998-06-30 2002-05-14 Neuromed Technologies, Inc. Preferentially substituted calcium channel blockers
US7186726B2 (en) 1998-06-30 2007-03-06 Neuromed Pharmaceuticals Ltd. Preferentially substituted calcium channel blockers
US6310059B1 (en) 1998-06-30 2001-10-30 Neuromed Technologies, Inc. Fused ring calcium channel blockers
AU2014225550C1 (en) 2013-03-08 2017-08-17 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Potent and selective inhibitors of monoamine transporters; method of making; and use thereof
US9856238B2 (en) * 2015-02-11 2018-01-02 Sunovion Pharmaceuticals Inc. 1-heterocyclyl isochromanyl compounds and analogs for treating CNS disorders
US11365195B2 (en) 2017-11-13 2022-06-21 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Atypical inhibitors of monoamine transporters; method of making; and use thereof

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1552004A (en) * 1976-05-26 1979-09-05 Takeda Chemical Industries Ltd Isochroman derivatives
EP0450689A1 (en) * 1990-04-02 1991-10-09 Akzo Nobel N.V. New isochromane derivatives

Also Published As

Publication number Publication date
NZ238243A (en) 1992-12-23
PT97766A (pt) 1992-03-31
DK0458387T3 (da) 1996-10-21
DE69120603T2 (de) 1997-01-02
FI912400A (fi) 1991-11-26
IE73232B1 (en) 1997-05-21
FI912400A0 (fi) 1991-05-17
DE69120603D1 (de) 1996-08-08
AU643277B2 (en) 1993-11-11
KR910020004A (ko) 1991-12-19
CA2042861A1 (en) 1991-11-26
ATE140001T1 (de) 1996-07-15
EP0458387B1 (en) 1996-07-03
EP0458387A1 (en) 1991-11-27
ES2091283T3 (es) 1996-11-01
AU7733491A (en) 1991-11-28
GR3021084T3 (en) 1996-12-31
PT97766B (pt) 1998-10-30
JPH04253970A (ja) 1992-09-09
IE911589A1 (en) 1991-12-04

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