ZA912063B - Process and intermediates for 2r-benzyl-chroman-6-carbaldehyde - Google Patents

Process and intermediates for 2r-benzyl-chroman-6-carbaldehyde

Info

Publication number
ZA912063B
ZA912063B ZA912063A ZA912063A ZA912063B ZA 912063 B ZA912063 B ZA 912063B ZA 912063 A ZA912063 A ZA 912063A ZA 912063 A ZA912063 A ZA 912063A ZA 912063 B ZA912063 B ZA 912063B
Authority
ZA
South Africa
Prior art keywords
chroman
carbaldehyde
intermediates
benzyl
benzylchroman
Prior art date
Application number
ZA912063A
Other languages
English (en)
Inventor
Frank John Urban
John Urban Frank
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=23973911&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ZA912063(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Pfizer filed Critical Pfizer
Publication of ZA912063B publication Critical patent/ZA912063B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P41/00—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P41/00—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture
    • C12P41/003—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by ester formation, lactone formation or the inverse reactions
    • C12P41/004—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by ester formation, lactone formation or the inverse reactions by esterification of alcohol- or thiol groups in the enantiomers or the inverse reaction
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
    • C07D311/66—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4 with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Analytical Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Genetics & Genomics (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pyrane Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Plural Heterocyclic Compounds (AREA)
ZA912063A 1990-03-21 1991-03-20 Process and intermediates for 2r-benzyl-chroman-6-carbaldehyde ZA912063B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/496,737 US5089637A (en) 1990-03-21 1990-03-21 Process and intermediates for 2r-benzyl-chroman-6-carbaldehyde

Publications (1)

Publication Number Publication Date
ZA912063B true ZA912063B (en) 1992-10-28

Family

ID=23973911

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA912063A ZA912063B (en) 1990-03-21 1991-03-20 Process and intermediates for 2r-benzyl-chroman-6-carbaldehyde

Country Status (20)

Country Link
US (1) US5089637A (ja)
EP (1) EP0448254B1 (ja)
JP (1) JPH0764838B2 (ja)
KR (1) KR940005601B1 (ja)
AT (1) ATE117299T1 (ja)
AU (1) AU620756B2 (ja)
CA (1) CA2038610C (ja)
DE (1) DE69106753T2 (ja)
DK (1) DK0448254T3 (ja)
ES (1) ES2067148T3 (ja)
FI (1) FI97385C (ja)
GR (1) GR3015390T3 (ja)
HU (1) HUT61603A (ja)
IE (1) IE64066B1 (ja)
IL (1) IL97549A0 (ja)
MY (1) MY106374A (ja)
NO (1) NO179680C (ja)
NZ (1) NZ237466A (ja)
PT (1) PT97070B (ja)
ZA (1) ZA912063B (ja)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5658796A (en) * 1995-06-07 1997-08-19 Seprachem, Inc. Optical resolution of alkyl chroman-2-carboxylates
EP1073762A1 (en) * 1998-04-28 2001-02-07 Novo Nordisk A/S Enzymatic resolvation for obtaining a (-)-3,4-trans-diarylchroman
US6184005B1 (en) 1998-04-28 2001-02-06 Novo Nordisk A/S Enzymatic resolvation for obtaining a (−)-3,4-trans-diarylchroman
JPWO2003040382A1 (ja) * 2001-11-09 2005-03-03 株式会社カネカ 光学活性クロマン誘導体の製造法および中間体
EP1634958B1 (en) * 2003-06-04 2009-02-18 Mitsubishi Gas Chemical Company, Inc. Method for producing optically active chroman-carboxylate
TW200716595A (en) * 2005-04-22 2007-05-01 Wyeth Corp Chromane and chromene derivatives and uses thereof
KR100784850B1 (ko) * 2006-10-19 2007-12-14 충북대학교 산학협력단 크로만-2-카복실산 아릴아마이드 유도체, 그 제조방법 및이를 포함하는 ＮＦ-κＢ 저해제
IT1402974B1 (it) 2010-11-30 2013-09-27 Menarini Int Operations Lu Sa Processo per la preparazione del nebivololo.
FR2986804A1 (fr) * 2012-02-09 2013-08-16 Servier Lab Procede de synthese enzymatique de l'acide (7s) 3,4-dimethoxybicyclo[4.2.0]octa-1,3,5-triene 7-carboxylique ou de ses esters, et application a la synthese de l'ivabradine et de ses sels
US10010266B2 (en) 2013-03-15 2018-07-03 Airway Control Technologies, Llc Medical breathing apparatus

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4654362A (en) * 1983-12-05 1987-03-31 Janssen Pharmaceutica, N.V. Derivatives of 2,2'-iminobisethanol
KR930005004B1 (ko) * 1985-04-15 1993-06-11 쟈안센 파아마슈우티카 엔. 부이. 치환된 n-[(4-피페리디닐)알킬]이환 축합 옥사졸아민 및 티아졸아민의 제조방법
WO1986007056A1 (en) * 1985-05-21 1986-12-04 Pfizer Inc. Hypoglycemic thiazolidinediones
US5037747A (en) * 1988-01-26 1991-08-06 Hoffmann-La Roche Inc. Production of benzopyran-2-carboxylic acids and esters by enzymatic hydrolysis

Also Published As

Publication number Publication date
DE69106753D1 (de) 1995-03-02
NZ237466A (en) 1992-04-28
FI911356A0 (fi) 1991-03-20
EP0448254A3 (en) 1991-12-18
PT97070A (pt) 1991-10-31
NO911101D0 (no) 1991-03-19
US5089637A (en) 1992-02-18
EP0448254A2 (en) 1991-09-25
JPH04234871A (ja) 1992-08-24
ES2067148T3 (es) 1995-03-16
NO911101L (no) 1991-09-23
AU7369691A (en) 1991-11-14
JPH0764838B2 (ja) 1995-07-12
AU620756B2 (en) 1992-02-20
PT97070B (pt) 2001-05-31
GR3015390T3 (en) 1995-06-30
NO179680C (no) 1996-11-27
CA2038610A1 (en) 1991-09-22
NO179680B (no) 1996-08-19
FI97385C (fi) 1996-12-10
IL97549A0 (en) 1992-06-21
KR910016939A (ko) 1991-11-05
EP0448254B1 (en) 1995-01-18
FI97385B (fi) 1996-08-30
CA2038610C (en) 1999-03-09
ATE117299T1 (de) 1995-02-15
KR940005601B1 (ko) 1994-06-21
IE64066B1 (en) 1995-07-12
HUT61603A (en) 1993-01-28
DK0448254T3 (da) 1995-03-20
IE910938A1 (en) 1991-09-25
FI911356A (fi) 1991-09-22
HU910939D0 (en) 1991-10-28
MY106374A (en) 1995-05-30
DE69106753T2 (de) 1995-05-18

Similar Documents

Publication Publication Date Title
EP0448254A3 (en) Process and intermediates for 2r-benzyl-chroman-6-carbaldehyde
PT89553A (pt) Processo de preparacao de acidos 2-arilpropionicos opticamente activos
ATE70832T1 (de) Verfahren zur herstellung von 2-(4-fluorphenyl)alpha-methyl-5-benzoxazolessigs|ure.
FR2626289B1 (fr) Procede de preparation d'acides aryl-2 alkanoiques optiquement actifs
ES2128959A1 (es) Procedimiento de separacion de carbinoles.
AU556793B2 (en) Sorbinil and methylsorbinil
IL82034A0 (en) Enzymatic resolution of racemic 2-amino-1-alkanols
ES2051767T3 (es) Cetorreduccion estereoespecifica de esteres de acido carboxilico-biciclooctanodiona por microorganismos.
ES2055122T3 (es) Procedimiento de preparacion de acidos 2-ariloxi- o 2-ariltio-alcanoicos.
DE69123009D1 (de) Verfahren zur Herstellung optisch aktiver 3-Hydroxybutan-Derivate
DE3770024D1 (de) Herstellung von 9-alkenylesterverbindungen.
ATE132864T1 (de) Herstellung von dioxolanderivaten
DE69123402D1 (de) Verfahren zur Herstellung optisch aktiver Alpha-Hydroxyalkenderivate
IL99380A (en) Process for the preparation of acid addition salt of 3-amino-4-arylethyl-2-oxoazetidine acetic acid derivatives and n-beta-methyl acrylic acid ester intermediate therefor
MX9708398A (es) Procedimiento para la obtencion de ariluracilos substituidos.