ZA909987B - Novel fungal expression system - Google Patents

Novel fungal expression system

Info

Publication number
ZA909987B
ZA909987B ZA909987A ZA909987A ZA909987B ZA 909987 B ZA909987 B ZA 909987B ZA 909987 A ZA909987 A ZA 909987A ZA 909987 A ZA909987 A ZA 909987A ZA 909987 B ZA909987 B ZA 909987B
Authority
ZA
South Africa
Prior art keywords
dna molecules
hybrid vectors
novel dna
promoter
novel
Prior art date
Application number
ZA909987A
Other languages
English (en)
Inventor
Leendert Hendrik De Graaff
Hendrik De Graaff Leendert
Jacob Visser
Visser Jacob
Henriette Catharina Van Broeck
Catharina Van Den Br Henriette
Frank Buxton
Buxton Frank
Original Assignee
Ciba Geigy
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy filed Critical Ciba Geigy
Publication of ZA909987B publication Critical patent/ZA909987B/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/80Vectors or expression systems specially adapted for eukaryotic hosts for fungi
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52Cytokines; Lymphokines; Interferons
    • C07K14/555Interferons [IFN]
    • C07K14/56IFN-alpha
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10Transferases (2.)
    • C12N9/12Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/24Hydrolases (3) acting on glycosyl compounds (3.2)
    • C12N9/2402Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/88Lyases (4.)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y302/00Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
    • C12Y302/01Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
    • C12Y302/01015Polygalacturonase (3.2.1.15)
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/01Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/02Fusion polypeptide containing a localisation/targetting motif containing a signal sequence
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/70Fusion polypeptide containing domain for protein-protein interaction
    • C07K2319/74Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor
    • C07K2319/75Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor containing a fusion for activation of a cell surface receptor, e.g. thrombopoeitin, NPY and other peptide hormones

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Mycology (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Physics & Mathematics (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Mushroom Cultivation (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Preparation Of Fruits And Vegetables (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Analysing Materials By The Use Of Radiation (AREA)
  • Saccharide Compounds (AREA)
  • Compounds Of Unknown Constitution (AREA)
  • Confectionery (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Optical Communication System (AREA)
  • Circuits Of Receivers In General (AREA)
  • Selective Calling Equipment (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
ZA909987A 1990-01-29 1990-12-12 Novel fungal expression system ZA909987B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP90810068 1990-01-29

Publications (1)

Publication Number Publication Date
ZA909987B true ZA909987B (en) 1991-09-25

Family

ID=8205903

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA909987A ZA909987B (en) 1990-01-29 1990-12-12 Novel fungal expression system

Country Status (18)

Country Link
EP (1) EP0439997B1 (fr)
JP (1) JP3329472B2 (fr)
KR (1) KR0157411B1 (fr)
AT (1) ATE130034T1 (fr)
AU (1) AU645768B2 (fr)
CA (1) CA2032035C (fr)
DE (1) DE69023474T2 (fr)
DK (1) DK0439997T3 (fr)
ES (1) ES2079468T3 (fr)
FI (1) FI103206B1 (fr)
GR (1) GR3018044T3 (fr)
HU (1) HU210989B (fr)
IE (1) IE68457B1 (fr)
MX (1) MX23984A (fr)
NO (1) NO309283B1 (fr)
NZ (1) NZ236434A (fr)
PT (1) PT96310B (fr)
ZA (1) ZA909987B (fr)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE1005432A4 (nl) * 1991-10-01 1993-07-20 Dsm Nv Expressiecassette voor heterologe eiwitten.
DE69231995T2 (de) * 1991-12-09 2002-04-04 Unilever Plc Verfahren zur Herstellung/Sekretion eines Proteins durch einen transformiertenSchimmelpilz unter Verwendung von Expressions-/Sekretions- Regulationsregionenaus Aspergillus
AU677296B2 (en) * 1993-02-16 1997-04-17 Novozymes A/S An enzyme with pectin lyase activity
US5674728A (en) * 1993-11-03 1997-10-07 Novartis Corporation Aspergillus niger vacuolar aspartyl protease
US5981227A (en) * 1995-02-09 1999-11-09 Movartis Ag Process for the production of proteins
IL155741A0 (en) 2000-11-03 2003-12-23 Pbl Biomedical Lab Interferons, uses and compositions related thereto
DE10356218A1 (de) * 2003-12-03 2005-06-30 Bayer Cropscience Ag Verfahren zum Identifizieren von fungizid wirksamen Verbindungen basierend auf Pyruvatkinasen aus Pilzen
ES2375150T3 (es) * 2005-03-16 2012-02-27 Novozymes Adenium Biotech A/S Expresión recombinante de defensinas de insecto en aspergillus.

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1341116C (fr) * 1983-02-22 2000-10-17 Rae Lyn Burke Systemes d'expression de la levure avec des vecteurs ayant des promoteurs de gapdh ou pyk, et synthese de proteine etrangere
US4885249A (en) * 1984-12-05 1989-12-05 Allelix, Inc. Aspergillus niger transformation system
FI864473A (fi) * 1985-11-20 1987-05-21 Panlabs Inc Sammansatta yttryckskassetter foer fungaltransformering.

Also Published As

Publication number Publication date
EP0439997B1 (fr) 1995-11-08
DK0439997T3 (da) 1995-12-11
DE69023474D1 (de) 1995-12-14
NO905393D0 (no) 1990-12-13
MX23984A (es) 1994-02-28
FI103206B (fi) 1999-05-14
NO905393L (no) 1991-07-30
NZ236434A (en) 1992-08-26
GR3018044T3 (en) 1996-02-29
AU6846090A (en) 1991-08-01
KR910014507A (ko) 1991-08-31
HU908325D0 (en) 1991-07-29
CA2032035A1 (fr) 1991-07-30
PT96310B (pt) 1998-06-30
IE904481A1 (en) 1991-07-31
NO309283B1 (no) 2001-01-08
CA2032035C (fr) 2001-08-14
HU210989B (en) 1995-09-28
HUT56886A (en) 1991-10-28
IE68457B1 (en) 1996-06-26
PT96310A (pt) 1991-10-15
KR0157411B1 (ko) 1998-10-15
AU645768B2 (en) 1994-01-27
ATE130034T1 (de) 1995-11-15
FI906123A (fi) 1991-07-30
ES2079468T3 (es) 1996-01-16
EP0439997A1 (fr) 1991-08-07
FI103206B1 (fi) 1999-05-14
JP3329472B2 (ja) 2002-09-30
JPH05192150A (ja) 1993-08-03
DE69023474T2 (de) 1996-03-28
FI906123A0 (fi) 1990-12-12

Similar Documents

Publication Publication Date Title
EP0063953A3 (fr) Vecteurs de clonage de bacillus, molécules de DNA recombinant, hôtes de bacillus transformés par celles-ci et méthode pour l'expression de séquences de DNA étrangères et pour la production de polypeptides codés par ce DNA
HUT58798A (en) Process for producing growth factor of parenchimic hepatic celles, the gen for coding this and transformants for producing this factor
IE862307L (en) Production of foreign polypeptides in yeast hosts
ZA909987B (en) Novel fungal expression system
NZ212937A (en) Omega interferons: production by recombinant dna processes; pharmaceutical compositions
AU1462688A (en) Process for the production of proteins
CA2024487A1 (fr) Polygalacturonase codant un systeme d'expression fongique
FI924909A (fi) Biosyntetiskt foerfarande foer framstaellning av kemiska foereningar
DE59109072D1 (de) Klonierung der N-Methylhydantoinase
ATE113655T1 (de) Expressionsvektor zur regulierbaren expression von fremdgenen in prokaryonten.
BR9606440A (pt) Processo para classificar neuropatologia dna isolado e purificado polinucleotídeo quimérico vetor de expressão e célula hospedeira
Peberdy Genetic manipulation.
CA2128794A1 (fr) Promoteur aox2 mutant, vecteur contenant ce promoteur, transformant et production de proteine heterologue