ZA904717B - Tetrazole excitatory amino acid receptor antagonists - Google Patents
Tetrazole excitatory amino acid receptor antagonistsInfo
- Publication number
- ZA904717B ZA904717B ZA904717A ZA904717A ZA904717B ZA 904717 B ZA904717 B ZA 904717B ZA 904717 A ZA904717 A ZA 904717A ZA 904717 A ZA904717 A ZA 904717A ZA 904717 B ZA904717 B ZA 904717B
- Authority
- ZA
- South Africa
- Prior art keywords
- tetrazole
- amino acid
- receptor antagonists
- acid receptor
- excitatory amino
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Neurosurgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Neurology (AREA)
- Pharmacology & Pharmacy (AREA)
- Biomedical Technology (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Heart & Thoracic Surgery (AREA)
- Urology & Nephrology (AREA)
- Hospice & Palliative Care (AREA)
- Vascular Medicine (AREA)
- Cardiology (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US07/371,568 US4968678A (en) | 1988-02-19 | 1989-06-26 | Tetrazole excitatory amino acid receptor antagonists |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA904717B true ZA904717B (en) | 1992-02-26 |
Family
ID=23464503
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA904717A ZA904717B (en) | 1989-06-26 | 1990-06-18 | Tetrazole excitatory amino acid receptor antagonists |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US4968678A (xx) |
| EP (1) | EP0405834A3 (xx) |
| JP (1) | JPH0348679A (xx) |
| KR (1) | KR910000703A (xx) |
| CN (1) | CN1028024C (xx) |
| AU (1) | AU621498B2 (xx) |
| CA (1) | CA2019167A1 (xx) |
| FI (1) | FI903183A0 (xx) |
| HU (1) | HU206339B (xx) |
| IE (1) | IE902288A1 (xx) |
| IL (1) | IL94777A (xx) |
| MX (1) | MX21219A (xx) |
| NZ (1) | NZ234109A (xx) |
| PH (1) | PH26905A (xx) |
| PT (1) | PT94447B (xx) |
| RU (2) | RU1833385C (xx) |
| ZA (1) | ZA904717B (xx) |
Families Citing this family (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE87918T1 (de) * | 1988-02-19 | 1993-04-15 | Lilly Co Eli | Tetrazolverbindungen als antagonisten der excitatorischen aminosaeurerezeptoren. |
| US5594007A (en) * | 1991-04-18 | 1997-01-14 | Pfizer Inc. | Method for treating spinal cord trauma with phenolic 2-piperidino-1-alkanols |
| US5196421A (en) * | 1991-06-05 | 1993-03-23 | Eli Lilly And Company | Excitatory amino acid receptor antagonists in methods for the use thereof |
| US5153196A (en) * | 1991-06-05 | 1992-10-06 | Eli Lilly And Company | Excitatory amino acid receptor antagonists and methods for the use thereof |
| WO1993021181A1 (en) * | 1992-04-15 | 1993-10-28 | Merck Sharp & Dohme Limited | Azacyclic compounds |
| US5192751A (en) * | 1992-07-24 | 1993-03-09 | Eli Lilly And Company | Use of competitive NMDA receptor antagonists in the treatment of urinary incontinence |
| EP1614416A3 (en) * | 1993-03-29 | 2009-07-01 | BELLUS Health (International) Limited | Method for treating amyloidosis |
| US20040208875A1 (en) | 1995-03-15 | 2004-10-21 | Queen's University At Kingston | Method for treating amyloidosis |
| BR9408506A (pt) * | 1994-01-31 | 1997-08-05 | Pfizer | Compostos neuroprotetores |
| DE69531154T2 (de) * | 1994-08-18 | 2004-04-08 | Pfizer Inc. | Neuroprotektive 3-(piperidinyl-1)-chroman-4,7-diol und 1-(4-hyphoxyphenyl)-2-(piperidinyl-1)-alkanolderivate |
| US5880138A (en) * | 1996-10-01 | 1999-03-09 | Eli Lilly And Company | NMDA receptor selective antagonists |
| EP1551317A1 (en) * | 2002-10-04 | 2005-07-13 | Cook Urological Inc. | Rigid extractor with wire basket |
| US8043303B2 (en) * | 2002-10-04 | 2011-10-25 | Cook Medical Technologies Llc | Handle for interchangeable medical device |
| US20070010573A1 (en) | 2003-06-23 | 2007-01-11 | Xianqi Kong | Methods and compositions for treating amyloid-related diseases |
| US7244764B2 (en) | 2003-06-23 | 2007-07-17 | Neurochem (International) Limited | Methods and compositions for treating amyloid-related diseases |
| US7414076B2 (en) | 2003-06-23 | 2008-08-19 | Neurochem (International) Limited | Methods and compositions for treating amyloid-related diseases |
| WO2005084564A1 (en) * | 2004-02-27 | 2005-09-15 | Cook Urological Incorporated | Self-tensioning handle for endoscopic device |
| US8044100B2 (en) | 2004-12-22 | 2011-10-25 | Bellus Health Inc. | Methods and compositions for treating amyloid-related diseases |
| TW200716088A (en) | 2005-04-15 | 2007-05-01 | Neurochem Int Ltd | Formulations and methods for treating amyloidosis |
| CA2626867C (en) * | 2005-11-03 | 2015-08-11 | Vance Products Incorporated, D/B/A Cook Urological Incorporated | Articulating basket with simultaneous basket extension or basket retraction |
| ES2352801T3 (es) | 2005-12-22 | 2011-02-23 | Kiacta Sàrl | Tratamiento de nefropatía diabética. |
| ES2891278T3 (es) | 2006-10-12 | 2022-01-26 | Bhi Lp | Métodos, compuestos, composiciones y vehículos para suministrar ácido 3-amino-1-propanosulfónico |
| EP3427729A1 (en) | 2017-07-13 | 2019-01-16 | Paris Sciences et Lettres - Quartier Latin | Probenecid for use in treating epileptic diseases, disorders or conditions |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3536715A (en) * | 1967-03-24 | 1970-10-27 | Miles Lab | 2-lower alkyl-5-(omega-(4-phenyl-1-piperazinyl) lower alkyl)-2h-tetrazoles |
| CA1248531A (en) * | 1984-04-17 | 1989-01-10 | Jeffrey C. Watkins | 4-substituted piperazine-2-carboxylic acids |
| PH23848A (en) * | 1985-05-24 | 1989-11-23 | Ciba Geigy Ag | Certain phosphonic acids and derivatives |
| US4746653A (en) * | 1986-02-28 | 1988-05-24 | Ciba-Geigy Corporation | Certain hetero phosphonic acid derivatives of 2-piperidine or 2-tetrahydropyridinecarboxylates and esters thereof which are useful for the treatment of disorders responsive to blockade of the NMDA receptor in mammals |
| DE3768000D1 (de) * | 1986-11-21 | 1991-03-14 | Ciba Geigy Ag | Ungesaettigte phosphonsaeure und derivate. |
| ATE87918T1 (de) * | 1988-02-19 | 1993-04-15 | Lilly Co Eli | Tetrazolverbindungen als antagonisten der excitatorischen aminosaeurerezeptoren. |
-
1989
- 1989-06-26 US US07/371,568 patent/US4968678A/en not_active Expired - Fee Related
-
1990
- 1990-06-18 NZ NZ234109A patent/NZ234109A/en unknown
- 1990-06-18 ZA ZA904717A patent/ZA904717B/xx unknown
- 1990-06-18 IL IL9477790A patent/IL94777A/en not_active IP Right Cessation
- 1990-06-18 KR KR1019900008930A patent/KR910000703A/ko not_active Application Discontinuation
- 1990-06-18 CA CA002019167A patent/CA2019167A1/en not_active Abandoned
- 1990-06-19 MX MX2121990A patent/MX21219A/es unknown
- 1990-06-20 EP EP19900306753 patent/EP0405834A3/en not_active Ceased
- 1990-06-21 PH PH40711A patent/PH26905A/en unknown
- 1990-06-21 PT PT94447A patent/PT94447B/pt not_active IP Right Cessation
- 1990-06-22 AU AU57808/90A patent/AU621498B2/en not_active Ceased
- 1990-06-25 IE IE228890A patent/IE902288A1/en unknown
- 1990-06-25 HU HU903976A patent/HU206339B/hu not_active IP Right Cessation
- 1990-06-25 FI FI903183A patent/FI903183A0/fi not_active Application Discontinuation
- 1990-06-25 JP JP2166530A patent/JPH0348679A/ja active Pending
- 1990-06-25 RU SU904830299A patent/RU1833385C/ru active
- 1990-06-25 CN CN90103125A patent/CN1028024C/zh not_active Expired - Fee Related
-
1991
- 1991-12-10 RU SU915010214A patent/RU2089546C1/ru active
Also Published As
| Publication number | Publication date |
|---|---|
| JPH0348679A (ja) | 1991-03-01 |
| EP0405834A2 (en) | 1991-01-02 |
| HU206339B (en) | 1992-10-28 |
| AU5780890A (en) | 1991-01-03 |
| PH26905A (en) | 1992-12-03 |
| HUT54364A (en) | 1991-02-28 |
| CN1048385A (zh) | 1991-01-09 |
| PT94447A (pt) | 1991-02-08 |
| KR910000703A (ko) | 1991-01-30 |
| FI903183A0 (fi) | 1990-06-25 |
| IL94777A (en) | 1994-05-30 |
| IE902288A1 (en) | 1991-01-16 |
| IE902288L (en) | 1990-12-26 |
| RU1833385C (ru) | 1993-08-07 |
| EP0405834A3 (en) | 1991-12-27 |
| AU621498B2 (en) | 1992-03-12 |
| IL94777A0 (en) | 1991-04-15 |
| US4968678A (en) | 1990-11-06 |
| CN1028024C (zh) | 1995-03-29 |
| MX21219A (es) | 1993-11-01 |
| HU903976D0 (en) | 1990-11-28 |
| NZ234109A (en) | 1992-04-28 |
| CA2019167A1 (en) | 1990-12-26 |
| PT94447B (pt) | 1997-02-28 |
| RU2089546C1 (ru) | 1997-09-10 |
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