GB2216529B - Peptides useful as tachykinin antagonists - Google Patents

Peptides useful as tachykinin antagonists

Info

Publication number
GB2216529B
GB2216529B GB8905977A GB8905977A GB2216529B GB 2216529 B GB2216529 B GB 2216529B GB 8905977 A GB8905977 A GB 8905977A GB 8905977 A GB8905977 A GB 8905977A GB 2216529 B GB2216529 B GB 2216529B
Authority
GB
United Kingdom
Prior art keywords
peptides useful
tachykinin antagonists
tachykinin
antagonists
peptides
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
GB8905977A
Other versions
GB2216529A (en
GB8905977D0 (en
Inventor
Neil R Curtis
Brian J Williams
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Organon Pharma UK Ltd
Original Assignee
Merck Sharp and Dohme Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Sharp and Dohme Ltd filed Critical Merck Sharp and Dohme Ltd
Publication of GB8905977D0 publication Critical patent/GB8905977D0/en
Publication of GB2216529A publication Critical patent/GB2216529A/en
Application granted granted Critical
Publication of GB2216529B publication Critical patent/GB2216529B/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/22—Tachykinins, e.g. Eledoisins, Substance P; Related peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
GB8905977A 1988-03-25 1989-03-15 Peptides useful as tachykinin antagonists Expired - Lifetime GB2216529B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB888807246A GB8807246D0 (en) 1988-03-25 1988-03-25 Therapeutic agents

Publications (3)

Publication Number Publication Date
GB8905977D0 GB8905977D0 (en) 1989-04-26
GB2216529A GB2216529A (en) 1989-10-11
GB2216529B true GB2216529B (en) 1991-05-01

Family

ID=10634162

Family Applications (2)

Application Number Title Priority Date Filing Date
GB888807246A Pending GB8807246D0 (en) 1988-03-25 1988-03-25 Therapeutic agents
GB8905977A Expired - Lifetime GB2216529B (en) 1988-03-25 1989-03-15 Peptides useful as tachykinin antagonists

Family Applications Before (1)

Application Number Title Priority Date Filing Date
GB888807246A Pending GB8807246D0 (en) 1988-03-25 1988-03-25 Therapeutic agents

Country Status (1)

Country Link
GB (2) GB8807246D0 (en)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0360390A1 (en) * 1988-07-25 1990-03-28 Glaxo Group Limited Spirolactam derivatives
DE3915361A1 (en) * 1989-05-11 1990-11-15 Merck Patent Gmbh CYCLO PEPTIDE
AU638264B2 (en) * 1989-08-10 1993-06-24 Aventis Inc. Cyclic neurokinin a antagonists
DE4034829A1 (en) * 1990-11-02 1992-05-07 Merck Patent Gmbh CYCLOPEPTIDE
US5416191A (en) * 1991-04-01 1995-05-16 Cortech, Inc. Bradykinin antagonists
EP0586613A4 (en) * 1991-04-01 1994-08-24 Cortech Inc Bradykinin antagonists
CA2109843A1 (en) * 1991-05-24 1992-11-26 Roy Patterson Method of using substance p to treat allergy
US5560915A (en) * 1991-05-24 1996-10-01 Northwestern University Composition for treating IgE mediated allergies comprising substance P and allergen
DE69231395T3 (en) 1991-09-20 2005-07-21 Glaxo Group Ltd., Greenford New medical indication for tachykinin antagonists
IL99628A (en) * 1991-10-02 2004-07-25 Yissum Res Dev Co Processes for the preparation of cyclic peptides, and pharmaceutical compositions containing them
IT1262902B (en) * 1992-04-15 1996-07-22 Menarini Farma Ind TRICYCLIC COMPOUNDS ANTAGONISTS OF TACHYCHININS, THEIR PREPARATION AND THEIR USE IN PHARMACEUTICAL COMPOSITIONS.
US5731285A (en) * 1992-04-15 1998-03-24 A. Menatini Industrie Farmaceutiche Tachiquinine antagonist tricyclic compounds, preparation of same and pharmaceutical compositions containing such compounds
US5830854A (en) * 1992-12-14 1998-11-03 Merck Sharp & Dohme, Limited Method of treating cystic fibrosis using a tachykinin receptor antagonist
FR2728165A1 (en) 1994-12-19 1996-06-21 Oreal USE OF AN ANTAGONIST OF SUBSTANCE P FOR THE TREATMENT OF SKIN REDNESS OF NEUROGENIC ORIGIN
FR2728169A1 (en) 1994-12-19 1996-06-21 Oreal USE OF A SUBSTANCE P ANTAGONIST FOR THE TREATMENT OF PRURITUS AND EYE OR PALPEBRAL DYSESTHESIA
FR2728166A1 (en) 1994-12-19 1996-06-21 Oreal TOPICAL COMPOSITION CONTAINING AN ANTAGONIST OF SUBSTANCE P
FR2741262B1 (en) 1995-11-20 1999-03-05 Oreal USE OF A TNF-ALPHA ANTAGONIST FOR THE TREATMENT OF CUTANEOUS REDNESS OF NEUROGENIC ORIGIN
CN101641099A (en) 2007-01-24 2010-02-03 葛兰素集团有限公司 Pharmaceutical compositions comprising 3, 5-diamin0-6- (2, 3-dichl0phenyl) -l, 2, 4-triazine or r (-) -2, 4-diamino-5- (2, 3-dichlorophenyl) -6-fluoromethyl pyrimidine and an nk1
US9446029B2 (en) 2010-07-27 2016-09-20 Colorado State University Research Foundation Use of NK-1 receptor antagonists in management of visceral pain

Also Published As

Publication number Publication date
GB2216529A (en) 1989-10-11
GB8807246D0 (en) 1988-04-27
GB8905977D0 (en) 1989-04-26

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Legal Events

Date Code Title Description
PCNP Patent ceased through non-payment of renewal fee

Effective date: 20030315