ZA903939B - Substituted(quinolin-2-yl-methoxy)phenyl-acyl-sulphonamides and-cyanamides,processes for their preparation and their use in medicaments - Google Patents

Substituted(quinolin-2-yl-methoxy)phenyl-acyl-sulphonamides and-cyanamides,processes for their preparation and their use in medicaments

Info

Publication number
ZA903939B
ZA903939B ZA903939A ZA903939A ZA903939B ZA 903939 B ZA903939 B ZA 903939B ZA 903939 A ZA903939 A ZA 903939A ZA 903939 A ZA903939 A ZA 903939A ZA 903939 B ZA903939 B ZA 903939B
Authority
ZA
South Africa
Prior art keywords
quinolin
cyanamides
sulphonamides
ylmethoxy
medicaments
Prior art date
Application number
ZA903939A
Other languages
English (en)
Inventor
Siegfried Raddatz
Raddatz Siegfried
Klaus-Helmut Mohrs
Mohrs Klaus-Helmut
Romanis Fruchtmann
Fruchtmann Romanis
Christian Kohlsdorfer
Kohlsdorfer Christian
Pia Theisen-Popp
Theisen-Popp Pia
Reiner Mueller-Peddinghaus
Mueller-Peddinghaus Reiner
Original Assignee
Bayer Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ag filed Critical Bayer Ag
Publication of ZA903939B publication Critical patent/ZA903939B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/12—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D215/14—Radicals substituted by oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/20—Oxygen atoms
    • C07D215/22—Oxygen atoms attached in position 2 or 4
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pulmonology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Vascular Medicine (AREA)
  • Oncology (AREA)
  • Immunology (AREA)
  • Urology & Nephrology (AREA)
  • Communicable Diseases (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Quinoline Compounds (AREA)
ZA903939A 1989-05-23 1990-05-22 Substituted(quinolin-2-yl-methoxy)phenyl-acyl-sulphonamides and-cyanamides,processes for their preparation and their use in medicaments ZA903939B (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE3916663A DE3916663A1 (de) 1989-05-23 1989-05-23 Substituierte (chinolin-2-yl-methoxy)phenyl-acyl-sulfonamide und -cyanamide, verfahren zu ihrer herstellung und ihre verwendung in arzneimitteln
SG12695A SG12695G (en) 1989-05-23 1995-01-26 Substituted (quinoline-2-yl-methoxy) phenyl-acyl-sulphonamides and cyanamides process for their preparation and their use in medicines

Publications (1)

Publication Number Publication Date
ZA903939B true ZA903939B (en) 1991-03-27

Family

ID=25881158

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA903939A ZA903939B (en) 1989-05-23 1990-05-22 Substituted(quinolin-2-yl-methoxy)phenyl-acyl-sulphonamides and-cyanamides,processes for their preparation and their use in medicaments

Country Status (18)

Country Link
US (1) US5091392A (pt)
EP (1) EP0399291B1 (pt)
JP (1) JP3004678B2 (pt)
KR (1) KR100210214B1 (pt)
AT (1) ATE108777T1 (pt)
AU (1) AU627579B2 (pt)
CA (1) CA2017135C (pt)
DD (1) DD297961A5 (pt)
DE (2) DE3916663A1 (pt)
DK (1) DK0399291T3 (pt)
ES (1) ES2056294T3 (pt)
HK (1) HK33395A (pt)
HU (1) HU215833B (pt)
IE (1) IE63593B1 (pt)
IL (1) IL94465A (pt)
PT (1) PT94105B (pt)
SG (1) SG12695G (pt)
ZA (1) ZA903939B (pt)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4139751A1 (de) * 1991-12-03 1993-06-09 Bayer Ag, 5090 Leverkusen, De Thiazolyl substituierte chinolylmethoxyphenylessigsaeurederivate
DE4226649A1 (de) * 1992-08-12 1994-02-17 Bayer Ag Neue isobutylsubstituierte Methansulfonyl-chinolylmethoxyphenyl-cycloalkylessigsäureaminole
US5304563A (en) * 1991-02-22 1994-04-19 Bayer Aktiengesellschaft 2-substituted quinolines, and their use in medicaments
DE4105551A1 (de) * 1991-02-22 1992-08-27 Bayer Ag 2-substituierte chinoline, verfahren zu ihrer herstellung sowie ihre verwendung in arzneimitteln
DE4112533A1 (de) * 1991-04-17 1992-10-22 Bayer Ag Verfahren zur herstellung von enantiomerenreinen substituierten (chinolin-2-yl-methoxy)phenyl-essigsaeuren
DE4125270A1 (de) * 1991-07-31 1993-02-04 Bayer Ag Chinolin-2-yl-methoxybenzylhydroxyharnstoffe
DE4129742A1 (de) * 1991-09-06 1993-03-11 Bayer Ag Heterocyclisch substituierte chinolylmethoxy-phenylacetamide
US5391555A (en) * 1991-11-12 1995-02-21 Miles Inc. Methods for treating inflammatory bowel disease with leukotriene synthesis inhibitors
DE4139750A1 (de) * 1991-12-03 1993-06-09 Bayer Ag, 5090 Leverkusen, De Chinolylmethoxyphenylessigsaeure-acylamide und -harnstoffe
DE4139749A1 (de) * 1991-12-03 1993-06-09 Bayer Ag, 5090 Leverkusen, De Chinolylmethoxyphenyl-essigsaeureamide
US5360909A (en) * 1992-03-23 1994-11-01 Terumo Kabushiki Kaisha Phenoxyacetic acid compounds and medical preparations containing them
DE4215213A1 (de) * 1992-05-09 1993-11-11 Merck Patent Gmbh Arylacetamide
DE4226519A1 (de) * 1992-08-11 1994-02-17 Bayer Ag 3-Substituierte Chinolylmethoxy-phenylessigsäurederivate
DE4235133A1 (de) * 1992-10-19 1994-04-21 Bayer Ag Kristallines (R)-(-)-2-Cycloheptyl-N-methylsulfonyl-[4-(2-chinolinyl-methoxy)-phenyl]-acetamid
US5491172A (en) * 1993-05-14 1996-02-13 Warner-Lambert Company N-acyl sulfamic acid esters (or thioesters), N-acyl sulfonamides, and N-sulfonyl carbamic acid esters (or thioesters) as hypercholesterolemic agents
IL109431A (en) * 1993-05-14 2001-01-11 Warner Lambert Co Pharmaceutical compositions containing n-acyl sulfamic acid esters (or thioesters), n-acyl sulfonamides, and n-sulfonyl carbamic acid esters (or thioesters), for regulating plasma cholesterol concentration, and certain such novel compounds
DE4443891A1 (de) 1994-12-09 1996-06-13 Bayer Ag Heterocyclisch substituierte Oxy-phenyl-(phenyl)glycinolamide
DE4443892A1 (de) * 1994-12-09 1996-06-13 Bayer Ag 4-(Chinolin-2-yl-methoxy)-phenyl-essigsäurederivate
GB2356139A (en) * 1999-11-15 2001-05-16 Bayer Ag Use of substituted (quinolin-2-yl-methoxy)phenyl-acyl-sulphonamides and cyanamides for the treatment of diseases
BRPI0417543A (pt) 2003-12-12 2007-03-27 Wyeth Corp quinolinas úteis no tratamento de doença cardiovascular
EP2561870A1 (en) * 2007-03-30 2013-02-27 Tioga Pharmaceuticals, Inc. Kappa-Opiate Agonists For The Treatment Of Diarrhea-Predominant and Alternating Irritable Bowel Syndrome

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE68789T1 (de) * 1985-10-16 1991-11-15 Merck Frosst Canada Inc 2-substituierte chinoline.
DE3867401D1 (de) * 1987-03-18 1992-02-13 American Home Prod Sulfonylcarboxamide.
DE3927369A1 (de) * 1989-08-19 1991-02-21 Bayer Ag Substituierte n-(chinolin-2-yl-methoxy)benzyl-sulfonyl-harnstoffe
DE3927931A1 (de) * 1989-08-24 1991-02-28 Bayer Ag Disubstituierte (chinolin-2-yl-methoxy)phenylessigsaeure-derivate
DE3927930A1 (de) * 1989-08-24 1991-02-28 Bayer Ag Cyclisch substituierte (chinolin-2-yl-methoxy)phenyl-essig-saeure-derivate

Also Published As

Publication number Publication date
IE63593B1 (en) 1995-05-17
IE901851L (en) 1990-11-23
DD297961A5 (de) 1992-01-30
EP0399291B1 (de) 1994-07-20
PT94105B (pt) 1996-11-29
ES2056294T3 (es) 1994-10-01
HU215833B (hu) 2001-06-28
CA2017135A1 (en) 1990-11-23
DK0399291T3 (da) 1994-11-14
CA2017135C (en) 2001-07-10
HK33395A (en) 1995-03-17
SG12695G (en) 1995-06-16
US5091392A (en) 1992-02-25
KR100210214B1 (ko) 1999-07-15
IL94465A0 (en) 1991-03-10
JP3004678B2 (ja) 2000-01-31
DE3916663A1 (de) 1990-11-29
KR900018037A (ko) 1990-12-20
PT94105A (pt) 1991-01-08
HUT54655A (en) 1991-03-28
DE59006474D1 (de) 1994-08-25
HU903132D0 (en) 1990-10-28
AU5586790A (en) 1990-11-29
JPH035459A (ja) 1991-01-11
EP0399291A3 (de) 1991-03-06
ATE108777T1 (de) 1994-08-15
IL94465A (en) 1994-07-31
AU627579B2 (en) 1992-08-27
EP0399291A2 (de) 1990-11-28

Similar Documents

Publication Publication Date Title
ZA903939B (en) Substituted(quinolin-2-yl-methoxy)phenyl-acyl-sulphonamides and-cyanamides,processes for their preparation and their use in medicaments
PH31617A (en) Novel thienylcarboxylates of amino alcohols, theirquaternary products and use of these compounds.
DE3469342D1 (en) Pharmaceutical composition on the basis of valproic acid, and its manufacturing process
ES2008974A6 (es) Formulacion liquida de enzimas para aplicacion tecnica, utilizaciones y procedimientos de empleo para desencalado, adobo, remojo y desengrasado de pieles en tripa.
AU6701890A (en) Process for the production of biologically active protein
IL84446A0 (en) 3-pyrrolidinylthio-1-azabicyclo-(3.2.0)hept-2-ene-2-carboxylic acid derivatives,processes for the preparation thereof and pharmaceutical compositions containing the same
AU580973B2 (en) Novel polypeptides with an ``-amylase-inhibiting action, a process for their preparation, their use and pharmaceutical products
HUT34350A (en) Prcess for production of partable pills with deferred decreasing of the reagents
ZA881764B (en) Thiazole derivatives active on the cholinerigic system,process for obtention and pharmaceutical compositions
NO167213C (no) Komposittartikkel i form av en innlukningsgjenstand, samtfremgangsmaate for sulfonering av den innvendige overflateav en innlukningsgjenstand.
ZA906531B (en) Substituted n-(quinolin-2-yl-methoxy)benzyl-sulphonyl-ureas
EP0006614A3 (en) Pyridyl- and imidazopyridyloxypropanolamines, process for preparing the same and pharmaceutical compositions containing the same
IL91317A0 (en) New antibiotic,mersacidin,a process for the preparation thereof and the use thereof as a pharmaceutical
DE3869670D1 (de) Latex fuer die immobilisierung von physiologisch aktiven verbindungen und reaktiver latex, der diesen latex verwendet.
HUT59136A (en) Process for producing 3-(pyroglutamyl)-l-thiazolidine-4-carboxylic acid and its derivatives
EP0246861A3 (en) Pharmaceutical composition based on crotoxine, process for preparing the active component and the pharmaceutical composition
IL89204A0 (en) Veterinary composition,especially suitable for the treatment of mastitis
AU8082687A (en) 2,6-diamino-3-halobenzylpyridines and processes for their manufacture as well as their use in pharmaceuticals
ES8300475A1 (es) Un procedimiento para la preparacion de un alergeno
DE3469438D1 (en) Novel, physiologically active substance, process for production thereof and pharmaceutical composition containing the same
IL86752A (en) Thiophene derivatives and their preparation and their use as intermediates in the preparation of n-(2,4-dimethylthien-3-yl) -n-(1-methoxyprop-2-yl) - chloroacetamide
AU2046888A (en) Process for the preparation of n6-benzyloxycarbonyl-2,6- diaminopimelamic acid in the l, l or d, d or racemic forms
AU6816390A (en) New phenoxyalkylcarboxylic acid amides, processes for the preparation thereof and pharmaceutical compositions containing them
ATE32496T1 (de) Pharmazeutische zusammensetzung auf basis von valproinsaeure und herstellungsverfahren derselben.
IE873354L (en) New pyrrolobenzimidazoles, processes for the preparation¹thereof and pharmaceutical compositions containing them.