ES2056294T3 - (quinolin-2-il-metoxi)fenil-acil-sulfonamidas y -cianamidas substituidas, procedimiento para su obtencion y su empleo en medicamentos. - Google Patents
(quinolin-2-il-metoxi)fenil-acil-sulfonamidas y -cianamidas substituidas, procedimiento para su obtencion y su empleo en medicamentos.Info
- Publication number
- ES2056294T3 ES2056294T3 ES90108775T ES90108775T ES2056294T3 ES 2056294 T3 ES2056294 T3 ES 2056294T3 ES 90108775 T ES90108775 T ES 90108775T ES 90108775 T ES90108775 T ES 90108775T ES 2056294 T3 ES2056294 T3 ES 2056294T3
- Authority
- ES
- Spain
- Prior art keywords
- quinolin
- sulphonamides
- medicines
- ylmethoxy
- cyanamides
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/20—Oxygen atoms
- C07D215/22—Oxygen atoms attached in position 2 or 4
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/12—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D215/14—Radicals substituted by oxygen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Heart & Thoracic Surgery (AREA)
- Pulmonology (AREA)
- Cardiology (AREA)
- Immunology (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Dermatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Plural Heterocyclic Compounds (AREA)
- Quinoline Compounds (AREA)
Abstract
EL INVENTO SE REFIERE A UNA NUEVA (QUINOLINA-2-ILO-METOXI)-FENILACILO-SULFONAMIDA Y CIANIMIDA, QUE SE OBTIENE POR AMIDACION DE ACIDOS (QUINOLINA-2-IL-METOXI)-FENIL-CARBONICO CON SULFONAMIDA O CIANIMIDA; SE PRODUCE TRATANDO (QUINOLINA-2-ILO-MTOXI) FENILACILAMIDA CON HALOGENURO DE ACIDO SULFURICO Y SE EMPLEA COMO MATERIA ACTIVA EN MEDICAMENTOS PARA INHIBIR LA LIPOXIGENASA.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE3916663A DE3916663A1 (de) | 1989-05-23 | 1989-05-23 | Substituierte (chinolin-2-yl-methoxy)phenyl-acyl-sulfonamide und -cyanamide, verfahren zu ihrer herstellung und ihre verwendung in arzneimitteln |
SG12695A SG12695G (en) | 1989-05-23 | 1995-01-26 | Substituted (quinoline-2-yl-methoxy) phenyl-acyl-sulphonamides and cyanamides process for their preparation and their use in medicines |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2056294T3 true ES2056294T3 (es) | 1994-10-01 |
Family
ID=25881158
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES90108775T Expired - Lifetime ES2056294T3 (es) | 1989-05-23 | 1990-05-10 | (quinolin-2-il-metoxi)fenil-acil-sulfonamidas y -cianamidas substituidas, procedimiento para su obtencion y su empleo en medicamentos. |
Country Status (18)
Country | Link |
---|---|
US (1) | US5091392A (es) |
EP (1) | EP0399291B1 (es) |
JP (1) | JP3004678B2 (es) |
KR (1) | KR100210214B1 (es) |
AT (1) | ATE108777T1 (es) |
AU (1) | AU627579B2 (es) |
CA (1) | CA2017135C (es) |
DD (1) | DD297961A5 (es) |
DE (2) | DE3916663A1 (es) |
DK (1) | DK0399291T3 (es) |
ES (1) | ES2056294T3 (es) |
HK (1) | HK33395A (es) |
HU (1) | HU215833B (es) |
IE (1) | IE63593B1 (es) |
IL (1) | IL94465A (es) |
PT (1) | PT94105B (es) |
SG (1) | SG12695G (es) |
ZA (1) | ZA903939B (es) |
Families Citing this family (21)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE4139751A1 (de) * | 1991-12-03 | 1993-06-09 | Bayer Ag, 5090 Leverkusen, De | Thiazolyl substituierte chinolylmethoxyphenylessigsaeurederivate |
DE4226649A1 (de) * | 1992-08-12 | 1994-02-17 | Bayer Ag | Neue isobutylsubstituierte Methansulfonyl-chinolylmethoxyphenyl-cycloalkylessigsäureaminole |
DE4105551A1 (de) * | 1991-02-22 | 1992-08-27 | Bayer Ag | 2-substituierte chinoline, verfahren zu ihrer herstellung sowie ihre verwendung in arzneimitteln |
US5304563A (en) * | 1991-02-22 | 1994-04-19 | Bayer Aktiengesellschaft | 2-substituted quinolines, and their use in medicaments |
DE4112533A1 (de) * | 1991-04-17 | 1992-10-22 | Bayer Ag | Verfahren zur herstellung von enantiomerenreinen substituierten (chinolin-2-yl-methoxy)phenyl-essigsaeuren |
DE4125270A1 (de) * | 1991-07-31 | 1993-02-04 | Bayer Ag | Chinolin-2-yl-methoxybenzylhydroxyharnstoffe |
DE4129742A1 (de) * | 1991-09-06 | 1993-03-11 | Bayer Ag | Heterocyclisch substituierte chinolylmethoxy-phenylacetamide |
US5391555A (en) * | 1991-11-12 | 1995-02-21 | Miles Inc. | Methods for treating inflammatory bowel disease with leukotriene synthesis inhibitors |
DE4139749A1 (de) * | 1991-12-03 | 1993-06-09 | Bayer Ag, 5090 Leverkusen, De | Chinolylmethoxyphenyl-essigsaeureamide |
DE4139750A1 (de) * | 1991-12-03 | 1993-06-09 | Bayer Ag, 5090 Leverkusen, De | Chinolylmethoxyphenylessigsaeure-acylamide und -harnstoffe |
US5360909A (en) * | 1992-03-23 | 1994-11-01 | Terumo Kabushiki Kaisha | Phenoxyacetic acid compounds and medical preparations containing them |
DE4215213A1 (de) * | 1992-05-09 | 1993-11-11 | Merck Patent Gmbh | Arylacetamide |
DE4226519A1 (de) * | 1992-08-11 | 1994-02-17 | Bayer Ag | 3-Substituierte Chinolylmethoxy-phenylessigsäurederivate |
DE4235133A1 (de) * | 1992-10-19 | 1994-04-21 | Bayer Ag | Kristallines (R)-(-)-2-Cycloheptyl-N-methylsulfonyl-[4-(2-chinolinyl-methoxy)-phenyl]-acetamid |
US5491172A (en) * | 1993-05-14 | 1996-02-13 | Warner-Lambert Company | N-acyl sulfamic acid esters (or thioesters), N-acyl sulfonamides, and N-sulfonyl carbamic acid esters (or thioesters) as hypercholesterolemic agents |
IL109431A (en) * | 1993-05-14 | 2001-01-11 | Warner Lambert Co | Pharmaceutical compositions containing n-acyl sulfamic acid esters (or thioesters), n-acyl sulfonamides, and n-sulfonyl carbamic acid esters (or thioesters), for regulating plasma cholesterol concentration, and certain such novel compounds |
DE4443892A1 (de) * | 1994-12-09 | 1996-06-13 | Bayer Ag | 4-(Chinolin-2-yl-methoxy)-phenyl-essigsäurederivate |
DE4443891A1 (de) | 1994-12-09 | 1996-06-13 | Bayer Ag | Heterocyclisch substituierte Oxy-phenyl-(phenyl)glycinolamide |
GB2356139A (en) * | 1999-11-15 | 2001-05-16 | Bayer Ag | Use of substituted (quinolin-2-yl-methoxy)phenyl-acyl-sulphonamides and cyanamides for the treatment of diseases |
PA8619901A1 (es) | 2003-12-12 | 2005-11-25 | Wyeth Corp | Quinolinas utiles en el tratamiento de enfermedades cardiovasculares |
KR101263225B1 (ko) * | 2007-03-30 | 2013-05-13 | 티오가 파마슈티칼스, 인코포레이티드 | 설사-우세형 및 교대형 과민성 장 증후군의 치료를 위한 카파-아편제 작용제 |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ATE68789T1 (de) * | 1985-10-16 | 1991-11-15 | Merck Frosst Canada Inc | 2-substituierte chinoline. |
WO1988006886A1 (en) * | 1987-03-18 | 1988-09-22 | American Home Products Corporation | Sulfonylcarboxamides |
DE3927369A1 (de) * | 1989-08-19 | 1991-02-21 | Bayer Ag | Substituierte n-(chinolin-2-yl-methoxy)benzyl-sulfonyl-harnstoffe |
DE3927931A1 (de) * | 1989-08-24 | 1991-02-28 | Bayer Ag | Disubstituierte (chinolin-2-yl-methoxy)phenylessigsaeure-derivate |
DE3927930A1 (de) * | 1989-08-24 | 1991-02-28 | Bayer Ag | Cyclisch substituierte (chinolin-2-yl-methoxy)phenyl-essig-saeure-derivate |
-
1989
- 1989-05-23 DE DE3916663A patent/DE3916663A1/de not_active Withdrawn
-
1990
- 1990-05-01 US US07/517,108 patent/US5091392A/en not_active Expired - Lifetime
- 1990-05-10 DK DK90108775.9T patent/DK0399291T3/da active
- 1990-05-10 AT AT90108775T patent/ATE108777T1/de not_active IP Right Cessation
- 1990-05-10 EP EP90108775A patent/EP0399291B1/de not_active Expired - Lifetime
- 1990-05-10 ES ES90108775T patent/ES2056294T3/es not_active Expired - Lifetime
- 1990-05-10 DE DE59006474T patent/DE59006474D1/de not_active Expired - Fee Related
- 1990-05-18 CA CA002017135A patent/CA2017135C/en not_active Expired - Fee Related
- 1990-05-21 PT PT94105A patent/PT94105B/pt not_active IP Right Cessation
- 1990-05-21 DD DD90340878A patent/DD297961A5/de not_active IP Right Cessation
- 1990-05-22 KR KR1019900007333A patent/KR100210214B1/ko not_active IP Right Cessation
- 1990-05-22 HU HU132/90A patent/HU215833B/hu not_active IP Right Cessation
- 1990-05-22 ZA ZA903939A patent/ZA903939B/xx unknown
- 1990-05-22 IL IL9446590A patent/IL94465A/en not_active IP Right Cessation
- 1990-05-22 IE IE185190A patent/IE63593B1/en not_active IP Right Cessation
- 1990-05-23 AU AU55867/90A patent/AU627579B2/en not_active Ceased
- 1990-05-23 JP JP2131439A patent/JP3004678B2/ja not_active Expired - Fee Related
-
1995
- 1995-01-26 SG SG12695A patent/SG12695G/en unknown
- 1995-03-09 HK HK33395A patent/HK33395A/xx not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
KR100210214B1 (ko) | 1999-07-15 |
IE901851L (en) | 1990-11-23 |
IL94465A0 (en) | 1991-03-10 |
DE59006474D1 (de) | 1994-08-25 |
IL94465A (en) | 1994-07-31 |
PT94105A (pt) | 1991-01-08 |
US5091392A (en) | 1992-02-25 |
EP0399291A2 (de) | 1990-11-28 |
ATE108777T1 (de) | 1994-08-15 |
DD297961A5 (de) | 1992-01-30 |
EP0399291B1 (de) | 1994-07-20 |
PT94105B (pt) | 1996-11-29 |
CA2017135C (en) | 2001-07-10 |
AU627579B2 (en) | 1992-08-27 |
CA2017135A1 (en) | 1990-11-23 |
IE63593B1 (en) | 1995-05-17 |
HK33395A (en) | 1995-03-17 |
JPH035459A (ja) | 1991-01-11 |
KR900018037A (ko) | 1990-12-20 |
JP3004678B2 (ja) | 2000-01-31 |
DE3916663A1 (de) | 1990-11-29 |
HU903132D0 (en) | 1990-10-28 |
HUT54655A (en) | 1991-03-28 |
HU215833B (hu) | 2001-06-28 |
DK0399291T3 (da) | 1994-11-14 |
AU5586790A (en) | 1990-11-29 |
SG12695G (en) | 1995-06-16 |
EP0399291A3 (de) | 1991-03-06 |
ZA903939B (en) | 1991-03-27 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG2A | Definitive protection |
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