ZA903564B - Pyrido-pyridazinone acetic acids for treating chronic diabetic complications - Google Patents

Pyrido-pyridazinone acetic acids for treating chronic diabetic complications

Info

Publication number
ZA903564B
ZA903564B ZA903564A ZA903564A ZA903564B ZA 903564 B ZA903564 B ZA 903564B ZA 903564 A ZA903564 A ZA 903564A ZA 903564 A ZA903564 A ZA 903564A ZA 903564 B ZA903564 B ZA 903564B
Authority
ZA
South Africa
Prior art keywords
pyrido
compounds
diabetic complications
chronic diabetic
treating chronic
Prior art date
Application number
ZA903564A
Other languages
English (en)
Inventor
Banavara Lakshmana Mylari
Lakshmana Mylari Banavara
William James Zembrowski
James Zembrowski William
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of ZA903564B publication Critical patent/ZA903564B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Obesity (AREA)
  • Emergency Medicine (AREA)
  • Hematology (AREA)
  • Reproductive Health (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Ophthalmology & Optometry (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Saccharide Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
ZA903564A 1989-05-11 1990-05-10 Pyrido-pyridazinone acetic acids for treating chronic diabetic complications ZA903564B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/350,417 US4996204A (en) 1989-05-11 1989-05-11 Pyrido[2,3-d]pyridazinones as aldose reductase inhibitors

Publications (1)

Publication Number Publication Date
ZA903564B true ZA903564B (en) 1992-08-26

Family

ID=23376622

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA903564A ZA903564B (en) 1989-05-11 1990-05-10 Pyrido-pyridazinone acetic acids for treating chronic diabetic complications

Country Status (18)

Country Link
US (1) US4996204A (da)
EP (1) EP0401981B1 (da)
JP (1) JPH0631235B2 (da)
KR (1) KR920003559B1 (da)
AT (1) ATE121743T1 (da)
AU (1) AU611610B2 (da)
CA (1) CA2016326C (da)
DE (1) DE69018876T2 (da)
DK (1) DK0401981T3 (da)
ES (1) ES2071016T3 (da)
FI (1) FI93013C (da)
HU (1) HU206714B (da)
IE (1) IE66029B1 (da)
IL (1) IL94302A (da)
NO (1) NO173938C (da)
NZ (1) NZ233599A (da)
PT (1) PT93984B (da)
ZA (1) ZA903564B (da)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4954629A (en) * 1989-05-11 1990-09-04 Pfizer Inc. Process and intermediates for the preparation of oxophthalazinyl acetic acids and analogs thereof
US5716954A (en) * 1991-10-09 1998-02-10 Syntex U.S.A. Inc. Benzopyridazinone and pyridopyridazinone compounds
AU683620B2 (en) * 1992-09-28 1997-11-20 Pfizer Inc. Substituted pyrimidines for control of diabetic complications
GB9314412D0 (en) * 1993-07-13 1993-08-25 Rhone Poulenc Agriculture New compositions of matter
KR100584650B1 (ko) * 1998-03-31 2006-05-30 디 인스티튜트스 포 파마슈티컬 디스커버리, 엘엘씨 치환된 인돌알칸산
TNSN99224A1 (fr) 1998-12-01 2005-11-10 Inst For Pharm Discovery Inc Methodes de reduction des niveaux de glucose et triglyceride en serum et pour suppression de l'antigenese utilisant les acides la indolealkanoique
MXPA03004871A (es) * 2000-11-30 2003-08-19 Pfizer Prod Inc Combinacion de agonistas de gaba e inhibidores de aldosa-reductasa.
ES2240657T3 (es) 2001-02-28 2005-10-16 Pfizer Products Inc. Compuestos de sulfonilpiridazinona utiles como inhibidores de aldosa reductasa.
EE200300470A (et) * 2001-03-30 2004-02-16 Pfizer Products Inc. Aldoosreduktaasi püridasinooninhibiitorid
HUP0303920A3 (en) * 2001-04-30 2004-07-28 Pfizer Prod Inc Pharmaceutical compositions containing combinations of aldose reductase inhibitor pyridazinons and cyclooxygenase 2 inhibitors
AU761191B2 (en) 2001-05-24 2003-05-29 Pfizer Products Inc. Therapies for tissue damage resulting from ischemia
US7572910B2 (en) * 2003-02-20 2009-08-11 Pfizer, Inc. Pyridazinone aldose reductase inhibitors
US8916563B2 (en) 2010-07-16 2014-12-23 The Trustees Of Columbia University In The City Of New York Aldose reductase inhibitors and uses thereof
DK3597650T3 (da) * 2010-07-16 2022-11-21 Univ Columbia Aldosereduktasehæmmere og anvendelser deraf
EP4316603A3 (en) 2016-06-21 2024-04-17 The Trustees of Columbia University in the City of New York 4-oxo-3,4-dihydrothieno[3,4-d]pyridazine compounds as aldose reductase inhibitors and methods of use thereof
EP4417260A2 (en) 2017-07-28 2024-08-21 Applied Therapeutics, Inc. Compositions and methods for treating galactosemia
AU2020268368A1 (en) 2019-05-07 2022-01-06 Ucl Business Ltd Treatment and detection of inherited neuropathies and associated disorders

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3821383A (en) * 1972-07-10 1974-06-28 Ayerst Mckenna & Harrison Compositions for and a method of treating diabetic complications
DE2708187A1 (de) * 1977-02-25 1978-08-31 Thomae Gmbh Dr K Neue pyrido-pyridazin-one
IE47592B1 (en) * 1977-12-29 1984-05-02 Ici Ltd Enzyme inhibitory phthalazin-4-ylacetic acid derivatives, pharmaceutical compositions thereof,and process for their manufacture
US4209527A (en) * 1979-05-16 1980-06-24 Pfizer Inc. Benzimidazolone derivatives
CA1160518A (en) * 1979-07-06 1984-01-17 E. I. Du Pont De Nemours And Company Coated cookware with fep topcoat
DE3684410D1 (de) * 1985-11-07 1992-04-23 Pfizer Heterocyclische oxophthalazinylessigsaeure.
US4954629A (en) * 1989-05-11 1990-09-04 Pfizer Inc. Process and intermediates for the preparation of oxophthalazinyl acetic acids and analogs thereof

Also Published As

Publication number Publication date
CA2016326C (en) 1995-05-30
IE66029B1 (en) 1995-11-29
AU611610B2 (en) 1991-06-13
IL94302A0 (en) 1991-03-10
DK0401981T3 (da) 1995-09-04
JPH035481A (ja) 1991-01-11
NO173938C (no) 1994-02-23
KR900018092A (ko) 1990-12-20
PT93984A (pt) 1991-01-08
CA2016326A1 (en) 1990-11-11
HU902996D0 (en) 1990-09-28
FI902335A0 (fi) 1990-05-10
IE901701L (en) 1990-11-11
ES2071016T3 (es) 1995-06-16
DE69018876T2 (de) 1995-08-24
NZ233599A (en) 1991-07-26
JPH0631235B2 (ja) 1994-04-27
IL94302A (en) 1994-01-25
EP0401981A1 (en) 1990-12-12
KR920003559B1 (ko) 1992-05-04
NO902070L (no) 1990-11-12
NO902070D0 (no) 1990-05-10
HUT54683A (en) 1991-03-28
EP0401981B1 (en) 1995-04-26
FI93013C (fi) 1995-02-10
PT93984B (pt) 1996-11-29
FI93013B (fi) 1994-10-31
NO173938B (no) 1993-11-15
US4996204A (en) 1991-02-26
AU5490590A (en) 1990-11-15
HU206714B (en) 1992-12-28
DE69018876D1 (de) 1995-06-01
ATE121743T1 (de) 1995-05-15

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