ZA90140B - Anti-inflammatory 1-heteroaryloxindole-3-carboxamides - Google Patents
Anti-inflammatory 1-heteroaryloxindole-3-carboxamidesInfo
- Publication number
- ZA90140B ZA90140B ZA90140A ZA90140A ZA90140B ZA 90140 B ZA90140 B ZA 90140B ZA 90140 A ZA90140 A ZA 90140A ZA 90140 A ZA90140 A ZA 90140A ZA 90140 B ZA90140 B ZA 90140B
- Authority
- ZA
- South Africa
- Prior art keywords
- furyl
- thienyl
- alkyl
- heteroaryloxindole
- carboxamides
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Indole Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/US1989/000080 WO1990008146A1 (fr) | 1989-01-10 | 1989-01-10 | 1-heteroarylindoxyle-3-carboxamides anti-inflammatoires |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA90140B true ZA90140B (en) | 1991-08-28 |
Family
ID=22214773
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA90140A ZA90140B (en) | 1989-01-10 | 1990-01-09 | Anti-inflammatory 1-heteroaryloxindole-3-carboxamides |
Country Status (20)
| Country | Link |
|---|---|
| US (1) | US5128352A (fr) |
| EP (1) | EP0378357B1 (fr) |
| JP (1) | JPH0678337B2 (fr) |
| KR (1) | KR920006784B1 (fr) |
| AT (1) | ATE100096T1 (fr) |
| AU (1) | AU616090B2 (fr) |
| CA (1) | CA2007651C (fr) |
| DE (1) | DE69005833T2 (fr) |
| DK (1) | DK0378357T3 (fr) |
| ES (1) | ES2062318T3 (fr) |
| FI (1) | FI94247C (fr) |
| HU (1) | HU217072B (fr) |
| IE (1) | IE61796B1 (fr) |
| IL (1) | IL92961A0 (fr) |
| MY (1) | MY106261A (fr) |
| NO (1) | NO178193C (fr) |
| NZ (1) | NZ232038A (fr) |
| PT (1) | PT92801B (fr) |
| WO (1) | WO1990008146A1 (fr) |
| ZA (1) | ZA90140B (fr) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6136839A (en) * | 1995-06-12 | 2000-10-24 | G. D. Searle & Co. | Treatment of inflammation and inflammation-related disorders with a combination of a cyclooxygenase-2 inhibitor and a 5-lipoxygenase inhibitor |
| SI3240785T1 (sl) * | 2014-12-29 | 2021-11-30 | THE UNITED STATES OF AMERICA, as represented by THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES, OFFICE OF TECHNOLOGY TRANSFER, NATIONAL INSTITUTES OF HEALTH | Malomolekulski zaviralci laktat dehidrogenaze in postopki za uporabo le-teh |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3749731A (en) * | 1971-07-08 | 1973-07-31 | Warner Lambert Co | 2-oxo-n-(2-thiazolyl)-3-indoline-carboxamide |
| US4176191A (en) * | 1977-09-06 | 1979-11-27 | Abbott Laboratories | Aminomethylene oxindoles |
| US4476307A (en) * | 1982-09-20 | 1984-10-09 | Pfizer Inc. | Heteroylidene indolone compounds |
| EP0153818B1 (fr) * | 1984-02-07 | 1989-03-15 | Pfizer Inc. | 2-Oxindoles 1,3-disubstitués et leur utilisation comme agents analgésiques et anti-inflammatoires |
| HU203350B (en) * | 1984-08-24 | 1991-07-29 | Pfizer | Process for producing antiinflammatory tricyclic oxindole derivatives |
| US4686224A (en) * | 1984-10-31 | 1987-08-11 | Pfizer Inc. | Oxindole antiinflammatory agents |
| US4644005A (en) * | 1984-10-31 | 1987-02-17 | Pfizer Inc. | Oxindole antiinflammatory agents |
| US4791129A (en) * | 1987-01-20 | 1988-12-13 | Pfizer Inc. | 1,3-dicarboxamidooxindoles as analgesic and antiinflammatory agents |
-
1989
- 1989-01-10 US US07/721,495 patent/US5128352A/en not_active Expired - Lifetime
- 1989-01-10 HU HU892128A patent/HU217072B/hu not_active IP Right Cessation
- 1989-01-10 WO PCT/US1989/000080 patent/WO1990008146A1/fr active IP Right Grant
-
1990
- 1990-01-03 IL IL92961A patent/IL92961A0/xx not_active IP Right Cessation
- 1990-01-08 PT PT92801A patent/PT92801B/pt not_active IP Right Cessation
- 1990-01-08 MY MYPI90000022A patent/MY106261A/en unknown
- 1990-01-08 NZ NZ232038A patent/NZ232038A/en unknown
- 1990-01-09 IE IE7490A patent/IE61796B1/en not_active IP Right Cessation
- 1990-01-09 EP EP90300228A patent/EP0378357B1/fr not_active Expired - Lifetime
- 1990-01-09 AT AT90300228T patent/ATE100096T1/de not_active IP Right Cessation
- 1990-01-09 KR KR1019900000166A patent/KR920006784B1/ko not_active IP Right Cessation
- 1990-01-09 AU AU47817/90A patent/AU616090B2/en not_active Ceased
- 1990-01-09 ES ES90300228T patent/ES2062318T3/es not_active Expired - Lifetime
- 1990-01-09 DE DE90300228T patent/DE69005833T2/de not_active Expired - Fee Related
- 1990-01-09 DK DK90300228.5T patent/DK0378357T3/da active
- 1990-01-09 ZA ZA90140A patent/ZA90140B/xx unknown
- 1990-01-10 JP JP2003287A patent/JPH0678337B2/ja not_active Expired - Lifetime
- 1990-01-12 CA CA002007651A patent/CA2007651C/fr not_active Expired - Fee Related
-
1991
- 1991-07-09 NO NO912696A patent/NO178193C/no not_active IP Right Cessation
- 1991-07-09 FI FI913325A patent/FI94247C/fi not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| WO1990008146A1 (fr) | 1990-07-26 |
| KR920006784B1 (ko) | 1992-08-17 |
| NO178193C (no) | 1996-02-07 |
| EP0378357A1 (fr) | 1990-07-18 |
| JPH0678337B2 (ja) | 1994-10-05 |
| AU4781790A (en) | 1990-07-19 |
| JPH02247174A (ja) | 1990-10-02 |
| FI94247C (fi) | 1995-08-10 |
| KR900011763A (ko) | 1990-08-02 |
| AU616090B2 (en) | 1991-10-17 |
| HU217072B (hu) | 1999-11-29 |
| IL92961A0 (en) | 1990-09-17 |
| CA2007651A1 (fr) | 1991-07-12 |
| DK0378357T3 (da) | 1994-02-14 |
| PT92801A (pt) | 1990-07-31 |
| FI94247B (fi) | 1995-04-28 |
| IE900074L (en) | 1990-07-10 |
| CA2007651C (fr) | 1997-08-19 |
| MY106261A (en) | 1995-04-29 |
| EP0378357B1 (fr) | 1994-01-12 |
| DE69005833D1 (de) | 1994-02-24 |
| PT92801B (pt) | 1995-12-29 |
| DE69005833T2 (de) | 1994-04-28 |
| HUT58084A (en) | 1992-01-28 |
| ES2062318T3 (es) | 1994-12-16 |
| NO912696D0 (no) | 1991-07-09 |
| NO912696L (no) | 1991-07-09 |
| NO178193B (no) | 1995-10-30 |
| IE61796B1 (en) | 1994-11-30 |
| NZ232038A (en) | 1991-06-25 |
| US5128352A (en) | 1992-07-07 |
| FI913325A0 (fi) | 1991-07-09 |
| ATE100096T1 (de) | 1994-01-15 |
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