ZA898385B - Compounds for the treatment of urinary incontinence - Google Patents

Compounds for the treatment of urinary incontinence

Info

Publication number
ZA898385B
ZA898385B ZA898385A ZA898385A ZA898385B ZA 898385 B ZA898385 B ZA 898385B ZA 898385 A ZA898385 A ZA 898385A ZA 898385 A ZA898385 A ZA 898385A ZA 898385 B ZA898385 B ZA 898385B
Authority
ZA
South Africa
Prior art keywords
lower alkyl
compounds
treatment
hydroxy
hydrogen
Prior art date
Application number
ZA898385A
Other languages
English (en)
Inventor
Bengt Christer Hans Sjoergen
Christer Hans Sjoergen Bengt
Henri Rene Mollberg
Rene Mollberg Henri
Sten Sture Kelfve
Sture Kelfve Sten
Bertil Valdemar Hansen
Valdemar Hansen Bertil
Original Assignee
Pharmacia Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pharmacia Ab filed Critical Pharmacia Ab
Publication of ZA898385B publication Critical patent/ZA898385B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/12—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms
    • C07D295/125—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/13—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00—Carboxylic acid amides
    • C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C233/34—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by amino groups
    • C07C233/35—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by amino groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom
    • C07C233/40—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by amino groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom having the carbon atom of the carboxamide group bound to an acyclic carbon atom of a carbon skeleton containing six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C235/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms
    • C07C235/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton
    • C07C235/32—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton containing six-membered aromatic rings
    • C07C235/34—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton containing six-membered aromatic rings having the nitrogen atoms of the carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Urology & Nephrology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Biomedical Technology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Underground Structures, Protecting, Testing And Restoring Foundations (AREA)
  • Medicinal Preparation (AREA)
  • Measuring Pulse, Heart Rate, Blood Pressure Or Blood Flow (AREA)
  • Measurement Of Velocity Or Position Using Acoustic Or Ultrasonic Waves (AREA)
  • Crystals, And After-Treatments Of Crystals (AREA)
  • Discharge Heating (AREA)
  • Table Equipment (AREA)
  • Finger-Pressure Massage (AREA)
  • Dowels (AREA)
ZA898385A 1988-11-04 1989-11-03 Compounds for the treatment of urinary incontinence ZA898385B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE8804003A SE8804003D0 (sv) 1988-11-04 1988-11-04 Compounds for the treatment of urinary incontinence

Publications (1)

Publication Number Publication Date
ZA898385B true ZA898385B (en) 1990-07-25

Family

ID=20373858

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA898385A ZA898385B (en) 1988-11-04 1989-11-03 Compounds for the treatment of urinary incontinence

Country Status (22)

Country Link
EP (1) EP0367040B1 (zh)
JP (1) JPH02218652A (zh)
KR (1) KR900007407A (zh)
CN (1) CN1043700A (zh)
AT (1) ATE88460T1 (zh)
AU (1) AU628879B2 (zh)
CA (1) CA2001641A1 (zh)
DD (1) DD289467A5 (zh)
DE (1) DE68906122T2 (zh)
DK (1) DK544689A (zh)
ES (1) ES2054980T3 (zh)
FI (1) FI895229A0 (zh)
HU (1) HU202828B (zh)
IE (1) IE63480B1 (zh)
NO (1) NO894384L (zh)
NZ (1) NZ231243A (zh)
PH (1) PH27014A (zh)
PT (1) PT92189B (zh)
RU (1) RU1833370C (zh)
SE (1) SE8804003D0 (zh)
TW (1) TW197944B (zh)
ZA (1) ZA898385B (zh)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5192779A (en) * 1989-02-14 1993-03-09 Fujisawa Pharmaceutical Co., Ltd. Substituted-acetamide compound and a process for the preparation thereof
US5066680A (en) * 1989-02-14 1991-11-19 Fujisawa Pharmaceutical Co., Ltd. Novel substituted-acetamide compound and a process for the preparation thereof
ZA921292B (en) * 1991-02-25 1993-08-23 Lilly Co Eli Treatment of lower urinary tract disorders.
TW344661B (en) * 1993-11-24 1998-11-11 Lilly Co Eli Pharmaceutical composition for treatment of incontinence
GB0328060D0 (en) * 2003-12-04 2004-01-07 Sod Conseils Rech Applic Botulinum toxin treatment
EP3288527B1 (en) * 2015-04-28 2020-02-19 Unilever PLC, a company registered in England and Wales under company no. 41424 of N-aralkylcarbonyldiamine compounds and personal care compositions comprising the same
CN107531655B (zh) 2015-04-28 2021-03-12 荷兰联合利华有限公司 N-芳烷基羰基-哌嗪和n-芳烷基羰基-高哌嗪化合物以及包含它们的个人护理组合物

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2009144A (en) * 1935-07-23 Substituted amides of amphatic-
US2831892A (en) * 1956-03-22 1958-04-22 Searle & Co N-(3-isopropylaminopropyl) diphenyl-acetamide and processes
FR2319337A1 (fr) * 1975-07-30 1977-02-25 Fabre Sa Pierre Gem diaryles possedant une activite antiarythmique utile en therapeutique cardiovasculaire
FR2333501A2 (fr) * 1975-12-03 1977-07-01 Science Union & Cie Nouveaux acetamides substitues leurs procedes d'obtention et les compositions pharmaceutiques en renfermant
FR2340724A2 (fr) * 1976-02-13 1977-09-09 Science Union & Cie Nouveaux diarylacetamides substitues, leurs procedes de preparation et les compositions pharmaceutiques en contenant
FR2421891A1 (fr) * 1977-10-17 1979-11-02 Fabre Sa Pierre Obtention industrielle d'amides de la pyrrolidine ethyl amine
FR2421892A1 (fr) * 1977-10-17 1979-11-02 Fabre Sa Pierre Procede de synthese industrielle du n(n' ethyl pyrrolidino-2 methyl) aadiphenylahydroxy acetamide
US5066680A (en) * 1989-02-14 1991-11-19 Fujisawa Pharmaceutical Co., Ltd. Novel substituted-acetamide compound and a process for the preparation thereof

Also Published As

Publication number Publication date
HU895648D0 (en) 1990-01-28
DK544689A (da) 1990-05-05
RU1833370C (en) 1993-08-07
PT92189A (pt) 1990-05-31
ES2054980T3 (es) 1994-08-16
IE893398L (en) 1990-05-04
FI895229A0 (fi) 1989-11-03
ATE88460T1 (de) 1993-05-15
PH27014A (en) 1993-02-01
CN1043700A (zh) 1990-07-11
PT92189B (pt) 1995-07-18
KR900007407A (ko) 1990-06-01
EP0367040A1 (en) 1990-05-09
DK544689D0 (da) 1989-11-01
CA2001641A1 (en) 1990-05-04
EP0367040B1 (en) 1993-04-21
NO894384L (no) 1990-05-07
SE8804003D0 (sv) 1988-11-04
NO894384D0 (no) 1989-11-03
HUT51597A (en) 1990-05-28
HU202828B (en) 1991-04-29
JPH02218652A (ja) 1990-08-31
NZ231243A (en) 1994-03-25
DE68906122D1 (de) 1993-05-27
IE63480B1 (en) 1995-05-03
AU4439489A (en) 1990-05-10
DE68906122T2 (de) 1997-05-22
TW197944B (zh) 1993-01-11
DD289467A5 (de) 1991-05-02
AU628879B2 (en) 1992-09-24

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