ZA889373B - Mercapto-acylamino acid antihypertensive - Google Patents

Mercapto-acylamino acid antihypertensive

Info

Publication number
ZA889373B
ZA889373B ZA889373A ZA889373A ZA889373B ZA 889373 B ZA889373 B ZA 889373B ZA 889373 A ZA889373 A ZA 889373A ZA 889373 A ZA889373 A ZA 889373A ZA 889373 B ZA889373 B ZA 889373B
Authority
ZA
South Africa
Prior art keywords
mercapto
acylamino acid
antihypertensive
acid antihypertensive
acylamino acids
Prior art date
Application number
ZA889373A
Other languages
English (en)
Inventor
Martin F Haslanger
F Haslanger Martin
Bernard Ray Neustadt
Ray Neustadt Bernard
Elizabeth Melva Smith
Melva Smith Elizabeth
Original Assignee
Schering Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US07/133,669 external-priority patent/US5061710A/en
Application filed by Schering Corp filed Critical Schering Corp
Publication of ZA889373B publication Critical patent/ZA889373B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C327/00—Thiocarboxylic acids
    • C07C327/02—Monothiocarboxylic acids
    • C07C327/04—Monothiocarboxylic acids having carbon atoms of thiocarboxyl groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C327/06—Monothiocarboxylic acids having carbon atoms of thiocarboxyl groups bound to hydrogen atoms or to acyclic carbon atoms to hydrogen atoms or to carbon atoms of an acyclic saturated carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C327/00—Thiocarboxylic acids
    • C07C327/02—Monothiocarboxylic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C07C323/50—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton
    • C07C323/51—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C323/60—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton with the carbon atom of at least one of the carboxyl groups bound to nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C327/00—Thiocarboxylic acids
    • C07C327/02—Monothiocarboxylic acids
    • C07C327/16—Monothiocarboxylic acids having carbon atoms of thiocarboxyl groups bound to carbon atoms of six-membered aromatic rings

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Saccharide Compounds (AREA)
ZA889373A 1987-12-16 1988-12-14 Mercapto-acylamino acid antihypertensive ZA889373B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/133,669 US5061710A (en) 1986-06-20 1987-12-16 Mercapto-acylamino acid antihypertensives

Publications (1)

Publication Number Publication Date
ZA889373B true ZA889373B (en) 1990-08-29

Family

ID=22459750

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA889373A ZA889373B (en) 1987-12-16 1988-12-14 Mercapto-acylamino acid antihypertensive

Country Status (18)

Country Link
EP (2) EP0322633B1 (de)
JP (1) JPH02503799A (de)
KR (1) KR940006770B1 (de)
CN (1) CN1033803A (de)
AT (1) ATE63741T1 (de)
AU (1) AU615976B2 (de)
DE (1) DE3862929D1 (de)
DK (1) DK146890A (de)
ES (1) ES2039578T3 (de)
FI (1) FI903010A0 (de)
GR (1) GR3002090T3 (de)
HU (1) HU204781B (de)
IL (1) IL88680A0 (de)
NO (1) NO902687L (de)
NZ (1) NZ227325A (de)
PT (1) PT89227B (de)
WO (1) WO1989005796A1 (de)
ZA (1) ZA889373B (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5599951A (en) * 1989-09-15 1997-02-04 Societe Civile Bioprojet Amino acid derivatives, the process for their preparation and their applications to therapy
FR2652087B1 (fr) * 1989-09-15 1993-10-15 Bioprojet Ste Civile Derives d'amino-acides, leur procede de preparation et leurs applications therapeutiques.
US5214181A (en) * 1989-11-27 1993-05-25 Santen Pharmaceutical Co., Ltd. Amino acid derivatives
US5173506A (en) * 1990-08-16 1992-12-22 Schering Corporation N-(mercaptoalkyl)ureas and carbamates
US5244889A (en) * 1991-11-26 1993-09-14 Ciba-Geigy Corporation Certain macrocyclic lactam derivatives
US5872281A (en) * 1995-03-07 1999-02-16 Santen Pharmaceutical Co., Ltd. Amino acid derivative having N,N-dialkylaminophenyl group
EP0947502B1 (de) * 1996-09-05 2006-06-21 Santen Pharmaceutical Co., Ltd. Schwefel enthaltende aminosäurederivate
CN105849087A (zh) 2013-12-27 2016-08-10 诺华丝国际股份有限公司 乙氧基化表面活性剂
US10584306B2 (en) 2017-08-11 2020-03-10 Board Of Regents Of The University Of Oklahoma Surfactant microemulsions

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4173704A (en) * 1976-05-10 1979-11-06 E. R. Squibb & Sons, Inc. Dithio aminoacid derivatives
CH637374A5 (en) * 1977-12-02 1983-07-29 Squibb & Sons Inc Substituted amino acids
FR2480747A1 (fr) * 1980-04-17 1981-10-23 Roques Bernard Derives d'acides amines et leur application therapeutique
US4401677A (en) * 1981-10-09 1983-08-30 E. R. Squibb & Sons, Inc. Enkephalinase inhibitors
DE3243370A1 (de) * 1982-11-24 1984-05-24 Basf Ag, 6700 Ludwigshafen Benzoylthioverbindungen, ihre herstellung und verwendung als arzneimittel
US5036054A (en) * 1988-02-11 1991-07-30 Warner-Lambert Company Renin inhibitors containing alpha-heteroatom amino acids
EP0355784A1 (de) * 1988-08-24 1990-02-28 Schering Corporation Merkaptoacylaminosäure enthaltende Antihypertensive
US4879309A (en) * 1988-09-27 1989-11-07 Schering Corporation Mercapto-acylamino acids as antihypertensives

Also Published As

Publication number Publication date
PT89227A (pt) 1989-12-29
KR900700443A (ko) 1990-08-13
FI903010A0 (fi) 1990-06-15
WO1989005796A1 (en) 1989-06-29
HU890380D0 (en) 1991-03-28
EP0390839A1 (de) 1990-10-10
NO902687D0 (no) 1990-06-15
CN1033803A (zh) 1989-07-12
DE3862929D1 (de) 1991-06-27
NO902687L (no) 1990-06-15
HU204781B (en) 1992-02-28
PT89227B (pt) 1993-07-30
JPH02503799A (ja) 1990-11-08
HUT54979A (en) 1991-04-29
KR940006770B1 (ko) 1994-07-27
DK146890D0 (da) 1990-06-15
AU615976B2 (en) 1991-10-17
AU2800289A (en) 1989-07-19
DK146890A (da) 1990-06-15
GR3002090T3 (en) 1992-12-30
NZ227325A (en) 1991-01-29
ATE63741T1 (de) 1991-06-15
IL88680A0 (en) 1989-07-31
EP0322633B1 (de) 1991-05-22
EP0322633A1 (de) 1989-07-05
ES2039578T3 (es) 1993-10-01

Similar Documents

Publication Publication Date Title
DE3169744D1 (en) Phosphinylalkanoyl substituted prolines
MY100641A (en) Neutral metalloendopeptidase inhibitors in the treatment of hypertension.
AU6998787A (en) Transglutaminase inhibitors
IE800014L (en) Tetrahydroquinoline-2-carboxylic acids
AU4840085A (en) Combinations of age inhibitors with dihydropyridines
EP0220107A3 (de) Verwendung von Angiotensin umwandelndem Enzymhemmer bei der Degeneration der Macula
DE3683729D1 (de) Gegenstand und verfahren zur enzymatischen neutralisierung von wasserstoffperoxyd.
ZA889373B (en) Mercapto-acylamino acid antihypertensive
AU6927087A (en) 1,2,3,4-tetrahydro-6-substituted-4-aryl(or heterocyclo)-3- substituted-2-thioxo(or oxo)-5-pyrimidinecarboxylic acids and esters
EP0302595A3 (en) Pinacidil for treatment of pulmonary hypertension or right heart failure
ATA47694A (de) Enzymatisches oxidationsverfahren zur umsetzung von cephalosporin c in glutaryl-7- aminocephalosporansäure
EP0181342A4 (de) Behandlungsverfahren gegen hohen blutdruck bei wirbeltieren.
IT8421077A0 (it) Metodo per la determinazione nelle urine dell'enzima di conversione dell'angiotensina (ace).
HUP9700652A1 (hu) Új xantinoxidáz enzimgátlók