ATE63741T1 - Mercapto-acylaminosaeure-antihypertensiver. - Google Patents
Mercapto-acylaminosaeure-antihypertensiver.Info
- Publication number
- ATE63741T1 ATE63741T1 AT88120795T AT88120795T ATE63741T1 AT E63741 T1 ATE63741 T1 AT E63741T1 AT 88120795 T AT88120795 T AT 88120795T AT 88120795 T AT88120795 T AT 88120795T AT E63741 T1 ATE63741 T1 AT E63741T1
- Authority
- AT
- Austria
- Prior art keywords
- mercapto
- acylaminosacid
- antihypertensive
- acylamino acids
- hypertension
- Prior art date
Links
- 230000003276 anti-hypertensive effect Effects 0.000 title 1
- 206010020772 Hypertension Diseases 0.000 abstract 2
- 239000005541 ACE inhibitor Substances 0.000 abstract 1
- 229940044094 angiotensin-converting-enzyme inhibitor Drugs 0.000 abstract 1
- 230000001746 atrial effect Effects 0.000 abstract 1
- 239000002833 natriuretic agent Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C327/00—Thiocarboxylic acids
- C07C327/02—Monothiocarboxylic acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C327/00—Thiocarboxylic acids
- C07C327/02—Monothiocarboxylic acids
- C07C327/04—Monothiocarboxylic acids having carbon atoms of thiocarboxyl groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C327/06—Monothiocarboxylic acids having carbon atoms of thiocarboxyl groups bound to hydrogen atoms or to acyclic carbon atoms to hydrogen atoms or to carbon atoms of an acyclic saturated carbon skeleton
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
- C07C323/50—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton
- C07C323/51—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton
- C07C323/60—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton with the carbon atom of at least one of the carboxyl groups bound to nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C327/00—Thiocarboxylic acids
- C07C327/02—Monothiocarboxylic acids
- C07C327/16—Monothiocarboxylic acids having carbon atoms of thiocarboxyl groups bound to carbon atoms of six-membered aromatic rings
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Cardiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Heart & Thoracic Surgery (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyrrole Compounds (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US07/133,669 US5061710A (en) | 1986-06-20 | 1987-12-16 | Mercapto-acylamino acid antihypertensives |
| EP88120795A EP0322633B1 (de) | 1987-12-16 | 1988-12-13 | Mercapto-acylaminosäure-Antihypertensiver |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE63741T1 true ATE63741T1 (de) | 1991-06-15 |
Family
ID=22459750
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT88120795T ATE63741T1 (de) | 1987-12-16 | 1988-12-13 | Mercapto-acylaminosaeure-antihypertensiver. |
Country Status (18)
| Country | Link |
|---|---|
| EP (2) | EP0322633B1 (de) |
| JP (1) | JPH02503799A (de) |
| KR (1) | KR940006770B1 (de) |
| CN (1) | CN1033803A (de) |
| AT (1) | ATE63741T1 (de) |
| AU (1) | AU615976B2 (de) |
| DE (1) | DE3862929D1 (de) |
| DK (1) | DK146890A (de) |
| ES (1) | ES2039578T3 (de) |
| FI (1) | FI903010A7 (de) |
| GR (1) | GR3002090T3 (de) |
| HU (1) | HU204781B (de) |
| IL (1) | IL88680A0 (de) |
| NO (1) | NO902687L (de) |
| NZ (1) | NZ227325A (de) |
| PT (1) | PT89227B (de) |
| WO (1) | WO1989005796A1 (de) |
| ZA (1) | ZA889373B (de) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2652087B1 (fr) * | 1989-09-15 | 1993-10-15 | Bioprojet Ste Civile | Derives d'amino-acides, leur procede de preparation et leurs applications therapeutiques. |
| US5599951A (en) * | 1989-09-15 | 1997-02-04 | Societe Civile Bioprojet | Amino acid derivatives, the process for their preparation and their applications to therapy |
| EP0455833B1 (de) * | 1989-11-27 | 1995-04-19 | Santen Pharmaceutical Co., Ltd. | Aminosäurederivate |
| US5173506A (en) * | 1990-08-16 | 1992-12-22 | Schering Corporation | N-(mercaptoalkyl)ureas and carbamates |
| US5244889A (en) * | 1991-11-26 | 1993-09-14 | Ciba-Geigy Corporation | Certain macrocyclic lactam derivatives |
| DE69632338T2 (de) * | 1995-03-07 | 2005-05-12 | Santen Pharmaceutical Co., Ltd | Neue aminosäurederivate, die eine n, n-dialkylaminophenylgruppe haben |
| ATE330939T1 (de) * | 1996-09-05 | 2006-07-15 | Santen Pharmaceutical Co Ltd | Schwefel enthaltende aminosäurederivate |
| CN105849087A (zh) | 2013-12-27 | 2016-08-10 | 诺华丝国际股份有限公司 | 乙氧基化表面活性剂 |
| US10584306B2 (en) | 2017-08-11 | 2020-03-10 | Board Of Regents Of The University Of Oklahoma | Surfactant microemulsions |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4173704A (en) * | 1976-05-10 | 1979-11-06 | E. R. Squibb & Sons, Inc. | Dithio aminoacid derivatives |
| CH637374A5 (en) * | 1977-12-02 | 1983-07-29 | Squibb & Sons Inc | Substituted amino acids |
| FR2480747A1 (fr) * | 1980-04-17 | 1981-10-23 | Roques Bernard | Derives d'acides amines et leur application therapeutique |
| US4401677A (en) * | 1981-10-09 | 1983-08-30 | E. R. Squibb & Sons, Inc. | Enkephalinase inhibitors |
| DE3243370A1 (de) * | 1982-11-24 | 1984-05-24 | Basf Ag, 6700 Ludwigshafen | Benzoylthioverbindungen, ihre herstellung und verwendung als arzneimittel |
| US5036054A (en) * | 1988-02-11 | 1991-07-30 | Warner-Lambert Company | Renin inhibitors containing alpha-heteroatom amino acids |
| WO1990002117A1 (en) * | 1988-08-24 | 1990-03-08 | Schering Corporation | Mercapto-acylamino acid antihypertensives |
| US4879309A (en) * | 1988-09-27 | 1989-11-07 | Schering Corporation | Mercapto-acylamino acids as antihypertensives |
-
1988
- 1988-12-13 AT AT88120795T patent/ATE63741T1/de not_active IP Right Cessation
- 1988-12-13 JP JP1500640A patent/JPH02503799A/ja active Pending
- 1988-12-13 FI FI903010A patent/FI903010A7/fi not_active Application Discontinuation
- 1988-12-13 WO PCT/US1988/004376 patent/WO1989005796A1/en not_active Ceased
- 1988-12-13 EP EP88120795A patent/EP0322633B1/de not_active Expired - Lifetime
- 1988-12-13 ES ES198888120795T patent/ES2039578T3/es not_active Expired - Lifetime
- 1988-12-13 HU HU89380A patent/HU204781B/hu unknown
- 1988-12-13 EP EP89900561A patent/EP0390839A1/de active Pending
- 1988-12-13 AU AU28002/89A patent/AU615976B2/en not_active Ceased
- 1988-12-13 DE DE8888120795T patent/DE3862929D1/de not_active Expired - Lifetime
- 1988-12-13 KR KR1019890701527A patent/KR940006770B1/ko not_active Expired - Lifetime
- 1988-12-14 ZA ZA889373A patent/ZA889373B/xx unknown
- 1988-12-14 IL IL88680A patent/IL88680A0/xx unknown
- 1988-12-14 NZ NZ227325A patent/NZ227325A/xx unknown
- 1988-12-14 CN CN88108633A patent/CN1033803A/zh active Pending
- 1988-12-15 PT PT89227A patent/PT89227B/pt not_active IP Right Cessation
-
1990
- 1990-06-15 DK DK146890A patent/DK146890A/da not_active Application Discontinuation
- 1990-06-15 NO NO90902687A patent/NO902687L/no unknown
-
1991
- 1991-06-07 GR GR91400768T patent/GR3002090T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| JPH02503799A (ja) | 1990-11-08 |
| PT89227A (pt) | 1989-12-29 |
| DK146890D0 (da) | 1990-06-15 |
| AU615976B2 (en) | 1991-10-17 |
| IL88680A0 (en) | 1989-07-31 |
| DE3862929D1 (de) | 1991-06-27 |
| DK146890A (da) | 1990-06-15 |
| NZ227325A (en) | 1991-01-29 |
| FI903010A0 (fi) | 1990-06-15 |
| ES2039578T3 (es) | 1993-10-01 |
| KR900700443A (ko) | 1990-08-13 |
| CN1033803A (zh) | 1989-07-12 |
| NO902687D0 (no) | 1990-06-15 |
| NO902687L (no) | 1990-06-15 |
| HU204781B (en) | 1992-02-28 |
| PT89227B (pt) | 1993-07-30 |
| GR3002090T3 (en) | 1992-12-30 |
| EP0322633B1 (de) | 1991-05-22 |
| HU890380D0 (en) | 1991-03-28 |
| FI903010A7 (fi) | 1990-06-15 |
| AU2800289A (en) | 1989-07-19 |
| EP0322633A1 (de) | 1989-07-05 |
| HUT54979A (en) | 1991-04-29 |
| WO1989005796A1 (en) | 1989-06-29 |
| KR940006770B1 (ko) | 1994-07-27 |
| ZA889373B (en) | 1990-08-29 |
| EP0390839A1 (de) | 1990-10-10 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification | ||
| REN | Ceased due to non-payment of the annual fee |