ATE63741T1 - Mercapto-acylaminosaeure-antihypertensiver. - Google Patents

Mercapto-acylaminosaeure-antihypertensiver.

Info

Publication number
ATE63741T1
ATE63741T1 AT88120795T AT88120795T ATE63741T1 AT E63741 T1 ATE63741 T1 AT E63741T1 AT 88120795 T AT88120795 T AT 88120795T AT 88120795 T AT88120795 T AT 88120795T AT E63741 T1 ATE63741 T1 AT E63741T1
Authority
AT
Austria
Prior art keywords
mercapto
acylaminosacid
antihypertensive
acylamino acids
hypertension
Prior art date
Application number
AT88120795T
Other languages
English (en)
Inventor
Martin F Haslanger
Bernard Ray Neustadt
Elizabeth Melva Smith
Original Assignee
Schering Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US07/133,669 external-priority patent/US5061710A/en
Application filed by Schering Corp filed Critical Schering Corp
Application granted granted Critical
Publication of ATE63741T1 publication Critical patent/ATE63741T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C327/00—Thiocarboxylic acids
    • C07C327/02—Monothiocarboxylic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C327/00—Thiocarboxylic acids
    • C07C327/02—Monothiocarboxylic acids
    • C07C327/04—Monothiocarboxylic acids having carbon atoms of thiocarboxyl groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C327/06—Monothiocarboxylic acids having carbon atoms of thiocarboxyl groups bound to hydrogen atoms or to acyclic carbon atoms to hydrogen atoms or to carbon atoms of an acyclic saturated carbon skeleton
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C07C323/50—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton
    • C07C323/51—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C323/60—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton with the carbon atom of at least one of the carboxyl groups bound to nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C327/00—Thiocarboxylic acids
    • C07C327/02—Monothiocarboxylic acids
    • C07C327/16—Monothiocarboxylic acids having carbon atoms of thiocarboxyl groups bound to carbon atoms of six-membered aromatic rings

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Pyrrole Compounds (AREA)
AT88120795T 1987-12-16 1988-12-13 Mercapto-acylaminosaeure-antihypertensiver. ATE63741T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US07/133,669 US5061710A (en) 1986-06-20 1987-12-16 Mercapto-acylamino acid antihypertensives
EP88120795A EP0322633B1 (de) 1987-12-16 1988-12-13 Mercapto-acylaminosäure-Antihypertensiver

Publications (1)

Publication Number Publication Date
ATE63741T1 true ATE63741T1 (de) 1991-06-15

Family

ID=22459750

Family Applications (1)

Application Number Title Priority Date Filing Date
AT88120795T ATE63741T1 (de) 1987-12-16 1988-12-13 Mercapto-acylaminosaeure-antihypertensiver.

Country Status (18)

Country Link
EP (2) EP0322633B1 (de)
JP (1) JPH02503799A (de)
KR (1) KR940006770B1 (de)
CN (1) CN1033803A (de)
AT (1) ATE63741T1 (de)
AU (1) AU615976B2 (de)
DE (1) DE3862929D1 (de)
DK (1) DK146890A (de)
ES (1) ES2039578T3 (de)
FI (1) FI903010A0 (de)
GR (1) GR3002090T3 (de)
HU (1) HU204781B (de)
IL (1) IL88680A0 (de)
NO (1) NO902687D0 (de)
NZ (1) NZ227325A (de)
PT (1) PT89227B (de)
WO (1) WO1989005796A1 (de)
ZA (1) ZA889373B (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5599951A (en) * 1989-09-15 1997-02-04 Societe Civile Bioprojet Amino acid derivatives, the process for their preparation and their applications to therapy
FR2652087B1 (fr) * 1989-09-15 1993-10-15 Bioprojet Ste Civile Derives d'amino-acides, leur procede de preparation et leurs applications therapeutiques.
ES2074257T3 (es) * 1989-11-27 1995-09-01 Santen Pharmaceutical Co Ltd Derivados de aminoacidos.
US5173506A (en) * 1990-08-16 1992-12-22 Schering Corporation N-(mercaptoalkyl)ureas and carbamates
US5244889A (en) * 1991-11-26 1993-09-14 Ciba-Geigy Corporation Certain macrocyclic lactam derivatives
WO1996027585A1 (fr) * 1995-03-07 1996-09-12 Santen Pharmaceutical Co., Ltd. Nouveaux derives aminoacides ayant un groupe n,n-dialkylaminophenyle
WO1998009943A1 (fr) * 1996-09-05 1998-03-12 Santen Pharmaceutical Co., Ltd. Nouveaux derives d'amino acide contenant du soufre
EP3087054A4 (de) 2013-12-27 2017-10-25 Novus International Inc. Ethoxylierte tenside
US10584306B2 (en) 2017-08-11 2020-03-10 Board Of Regents Of The University Of Oklahoma Surfactant microemulsions

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4173704A (en) * 1976-05-10 1979-11-06 E. R. Squibb & Sons, Inc. Dithio aminoacid derivatives
CH637374A5 (en) * 1977-12-02 1983-07-29 Squibb & Sons Inc Substituted amino acids
FR2480747A1 (fr) * 1980-04-17 1981-10-23 Roques Bernard Derives d'acides amines et leur application therapeutique
US4401677A (en) * 1981-10-09 1983-08-30 E. R. Squibb & Sons, Inc. Enkephalinase inhibitors
DE3243370A1 (de) * 1982-11-24 1984-05-24 Basf Ag, 6700 Ludwigshafen Benzoylthioverbindungen, ihre herstellung und verwendung als arzneimittel
US5036054A (en) * 1988-02-11 1991-07-30 Warner-Lambert Company Renin inhibitors containing alpha-heteroatom amino acids
AU4056389A (en) * 1988-08-24 1990-03-23 Schering Corporation Mercapto-acylamino acid antihypertensives
US4879309A (en) * 1988-09-27 1989-11-07 Schering Corporation Mercapto-acylamino acids as antihypertensives

Also Published As

Publication number Publication date
WO1989005796A1 (en) 1989-06-29
NO902687L (no) 1990-06-15
FI903010A0 (fi) 1990-06-15
NZ227325A (en) 1991-01-29
DK146890D0 (da) 1990-06-15
AU615976B2 (en) 1991-10-17
EP0322633A1 (de) 1989-07-05
IL88680A0 (en) 1989-07-31
KR940006770B1 (ko) 1994-07-27
EP0390839A1 (de) 1990-10-10
PT89227B (pt) 1993-07-30
NO902687D0 (no) 1990-06-15
KR900700443A (ko) 1990-08-13
EP0322633B1 (de) 1991-05-22
DE3862929D1 (de) 1991-06-27
HUT54979A (en) 1991-04-29
AU2800289A (en) 1989-07-19
CN1033803A (zh) 1989-07-12
ZA889373B (en) 1990-08-29
HU204781B (en) 1992-02-28
HU890380D0 (en) 1991-03-28
DK146890A (da) 1990-06-15
GR3002090T3 (en) 1992-12-30
JPH02503799A (ja) 1990-11-08
ES2039578T3 (es) 1993-10-01
PT89227A (pt) 1989-12-29

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee