ZA882375B - 3h-1,2,3-triazolo(4,5-d)pyrimidines - Google Patents
3h-1,2,3-triazolo(4,5-d)pyrimidinesInfo
- Publication number
- ZA882375B ZA882375B ZA882375A ZA882375A ZA882375B ZA 882375 B ZA882375 B ZA 882375B ZA 882375 A ZA882375 A ZA 882375A ZA 882375 A ZA882375 A ZA 882375A ZA 882375 B ZA882375 B ZA 882375B
- Authority
- ZA
- South Africa
- Prior art keywords
- cycloaliphatic
- aliphatic
- substituted
- triazolo
- pyrimidines
- Prior art date
Links
- GIIGHSIIKVOWKZ-UHFFFAOYSA-N 2h-triazolo[4,5-d]pyrimidine Chemical class N1=CN=CC2=NNN=C21 GIIGHSIIKVOWKZ-UHFFFAOYSA-N 0.000 title abstract 2
- 125000001931 aliphatic group Chemical group 0.000 abstract 2
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- 125000003277 amino group Chemical group 0.000 abstract 2
- HNHNPCZLKLSKHX-UHFFFAOYSA-N 3-benzyltriazolo[4,5-d]pyrimidine Chemical class N1=NC2=CN=CN=C2N1CC1=CC=CC=C1 HNHNPCZLKLSKHX-UHFFFAOYSA-N 0.000 abstract 1
- CIUQDSCDWFSTQR-UHFFFAOYSA-N [C]1=CC=CC=C1 Chemical compound [C]1=CC=CC=C1 CIUQDSCDWFSTQR-UHFFFAOYSA-N 0.000 abstract 1
- 239000013543 active substance Substances 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 125000004093 cyano group Chemical group *C#N 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical group 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH133387 | 1987-04-07 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA882375B true ZA882375B (en) | 1989-11-29 |
Family
ID=4208018
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA882375A ZA882375B (en) | 1987-04-07 | 1988-04-05 | 3h-1,2,3-triazolo(4,5-d)pyrimidines |
Country Status (19)
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5204353A (en) * | 1987-04-07 | 1993-04-20 | Ciba-Geigy Corporation | 3-benzyl-3H-1,2,3-triazolo[4,5-d]pyrimidines, compositions thereof, and method of treating epilepsy therewith |
| IT1222414B (it) * | 1987-07-31 | 1990-09-05 | Chiesi Farma Spa | Composizioni farmaceutiche contenenti trapidil,loro procedimento di preparazione e relaticvo impiego terapeutico |
| US5166209A (en) * | 1989-04-21 | 1992-11-24 | Burroughs Wellcome Co. | Pharmacologically active compounds |
| GB8909136D0 (en) * | 1989-04-21 | 1989-06-07 | Wellcome Found | Anticonvulsant pyridines and analogues thereof |
| US5498620A (en) * | 1989-05-19 | 1996-03-12 | The United States Of America As Represented By The Department Of Health And Human Services | Signal transduction inhibitor 1,2,3-triazolo compounds |
| US5359078A (en) * | 1989-05-19 | 1994-10-25 | The United States Of America As Represented By The Department Of Health And Human Services | Signal transduction inhibitor compounds |
| US5880129A (en) * | 1989-05-19 | 1999-03-09 | The United States Of America As Represented By The Department Of Health And Human Services | Methods of inhibiting invasion and metastasis of malignant solid tumors |
| US5240937A (en) * | 1990-04-20 | 1993-08-31 | Burroughs Wellcome Co. | Pharmaceutically active triazolopyridine compounds |
| MA26473A1 (fr) | 1997-03-01 | 2004-12-20 | Glaxo Group Ltd | Composes pharmacologiquement actifs. |
| DE19838705A1 (de) | 1998-08-26 | 2000-03-02 | Bayer Ag | Neue Dihydro-(1,2,3)-triazolo-[4,5-d]pyrimidin-7-one |
| WO2013172872A1 (en) * | 2012-05-15 | 2013-11-21 | Calasia Pharmaceuticals, Inc. | Pyrimidine diamine derivatives as inhibitors of cytosolic hsp90 |
| CN116854644A (zh) * | 2023-07-06 | 2023-10-10 | 浙江大学 | 5-氨基-1-烷基-1h-1,2,3-三氮唑-4-甲酰胺类化合物及其制备和应用 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1338235A (en) * | 1970-12-15 | 1973-11-21 | May & Baker Ltd | Azapurinones |
| US4076711A (en) * | 1976-04-05 | 1978-02-28 | Schering Corporation | Triazolo [4,5-d]-pyrimidines |
-
1988
- 1988-03-30 AT AT88810212T patent/ATE79624T1/de not_active IP Right Cessation
- 1988-03-30 DE DE8888810212T patent/DE3873812D1/de not_active Expired - Lifetime
- 1988-03-30 ES ES88810212T patent/ES2051886T3/es not_active Expired - Lifetime
- 1988-03-30 EP EP88810212A patent/EP0288431B1/de not_active Expired - Lifetime
- 1988-03-31 IL IL85947A patent/IL85947A/xx not_active IP Right Cessation
- 1988-04-05 DD DD88314431A patent/DD281190A5/de not_active IP Right Cessation
- 1988-04-05 ZA ZA882375A patent/ZA882375B/xx unknown
- 1988-04-05 PT PT87160A patent/PT87160B/pt active IP Right Grant
- 1988-04-06 MX MX1101288A patent/MX11012A/es unknown
- 1988-04-06 FI FI881582A patent/FI89359C/fi not_active IP Right Cessation
- 1988-04-06 HU HU881714A patent/HU206116B/hu not_active IP Right Cessation
- 1988-04-06 NO NO881466A patent/NO167919C/no unknown
- 1988-04-06 AU AU14302/88A patent/AU616880B2/en not_active Ceased
- 1988-04-06 JP JP63083212A patent/JPS63258881A/ja active Pending
- 1988-04-06 NZ NZ224154A patent/NZ224154A/en unknown
- 1988-04-06 DK DK184388A patent/DK167681B1/da active
- 1988-04-07 KR KR1019880003862A patent/KR880012603A/ko not_active Ceased
-
1990
- 1990-04-27 PH PH36735A patent/PH26444A/en unknown
-
1992
- 1992-11-13 GR GR920401775T patent/GR3006249T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| DD281190A5 (de) | 1990-08-01 |
| NO881466L (no) | 1988-10-10 |
| PT87160A (pt) | 1988-05-01 |
| MX11012A (es) | 1993-12-01 |
| DK167681B1 (da) | 1993-12-06 |
| DE3873812D1 (de) | 1992-09-24 |
| EP0288431A1 (de) | 1988-10-26 |
| FI89359C (fi) | 1993-09-27 |
| JPS63258881A (ja) | 1988-10-26 |
| NO881466D0 (no) | 1988-04-06 |
| FI881582A7 (fi) | 1988-10-08 |
| PH26444A (en) | 1992-07-15 |
| DK184388A (da) | 1988-10-08 |
| FI881582A0 (fi) | 1988-04-06 |
| EP0288431B1 (de) | 1992-08-19 |
| PT87160B (pt) | 1992-07-31 |
| ATE79624T1 (de) | 1992-09-15 |
| FI89359B (fi) | 1993-06-15 |
| GR3006249T3 (enrdf_load_stackoverflow) | 1993-06-21 |
| NO167919C (no) | 1991-12-27 |
| IL85947A0 (en) | 1988-09-30 |
| NZ224154A (en) | 1992-01-29 |
| AU616880B2 (en) | 1991-11-14 |
| AU1430288A (en) | 1988-10-13 |
| ES2051886T3 (es) | 1994-07-01 |
| DK184388D0 (da) | 1988-04-06 |
| NO167919B (no) | 1991-09-16 |
| KR880012603A (ko) | 1988-11-28 |
| IL85947A (en) | 1993-06-10 |
| HU206116B (en) | 1992-08-28 |
| HUT47577A (en) | 1989-03-28 |
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