AU1430288A - 3h-1,2,3-triazolo(4,5-d)pyrimidines - Google Patents

3h-1,2,3-triazolo(4,5-d)pyrimidines

Info

Publication number
AU1430288A
AU1430288A AU14302/88A AU1430288A AU1430288A AU 1430288 A AU1430288 A AU 1430288A AU 14302/88 A AU14302/88 A AU 14302/88A AU 1430288 A AU1430288 A AU 1430288A AU 1430288 A AU1430288 A AU 1430288A
Authority
AU
Australia
Prior art keywords
cycloaliphatic
aliphatic
substituted
triazolo
pyrimidines
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
AU14302/88A
Other versions
AU616880B2 (en
Inventor
Rene Meier
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis AG
Original Assignee
Ciba Geigy AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy AG filed Critical Ciba Geigy AG
Publication of AU1430288A publication Critical patent/AU1430288A/en
Application granted granted Critical
Publication of AU616880B2 publication Critical patent/AU616880B2/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

Novel 3H-1,2,3-triazolo[4,5-d]pyrimidine derivatives, in particular substituted 3-benzyl-3H-1,2,3-triazolo[4,5-d]pyrimidines of the formula <IMAGE> in which Ph denotes a phenyl radical which is substituted by halogen, lower alkyl, trifluoromethyl and/or cyano, R1 represents an amino group which is free or substituted by aliphatic, cycloaliphatic, cycloaliphatic-aliphatic and/or by acyl substituents and R2 represents hydrogen, lower alkyl or an amino group which is free or substituted by aliphatic, cycloaliphatic, cycloaliphatic-aliphatic and/or by acyl substituents, and their salts. These compounds can be used as pharmaceutical active substances and can be prepared in a manner known per se.
AU14302/88A 1987-04-07 1988-04-06 3h-1,2,3-triazolo(4,5-d)pyrimidines Ceased AU616880B2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH133387 1987-04-07
CH1333/87 1987-04-07

Publications (2)

Publication Number Publication Date
AU1430288A true AU1430288A (en) 1988-10-13
AU616880B2 AU616880B2 (en) 1991-11-14

Family

ID=4208018

Family Applications (1)

Application Number Title Priority Date Filing Date
AU14302/88A Ceased AU616880B2 (en) 1987-04-07 1988-04-06 3h-1,2,3-triazolo(4,5-d)pyrimidines

Country Status (19)

Country Link
EP (1) EP0288431B1 (en)
JP (1) JPS63258881A (en)
KR (1) KR880012603A (en)
AT (1) ATE79624T1 (en)
AU (1) AU616880B2 (en)
DD (1) DD281190A5 (en)
DE (1) DE3873812D1 (en)
DK (1) DK167681B1 (en)
ES (1) ES2051886T3 (en)
FI (1) FI89359C (en)
GR (1) GR3006249T3 (en)
HU (1) HU206116B (en)
IL (1) IL85947A (en)
MX (1) MX11012A (en)
NO (1) NO167919C (en)
NZ (1) NZ224154A (en)
PH (1) PH26444A (en)
PT (1) PT87160B (en)
ZA (1) ZA882375B (en)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU614297B2 (en) * 1987-07-31 1991-08-29 Chiesi Farmaceutici S.P.A. Pharmaceutical compositions containing trapidil, a process for the preparation thereof and related therapeutic use.
US5166209A (en) * 1989-04-21 1992-11-24 Burroughs Wellcome Co. Pharmacologically active compounds
US5240937A (en) * 1990-04-20 1993-08-31 Burroughs Wellcome Co. Pharmaceutically active triazolopyridine compounds

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5204353A (en) * 1987-04-07 1993-04-20 Ciba-Geigy Corporation 3-benzyl-3H-1,2,3-triazolo[4,5-d]pyrimidines, compositions thereof, and method of treating epilepsy therewith
GB8909136D0 (en) * 1989-04-21 1989-06-07 Wellcome Found Anticonvulsant pyridines and analogues thereof
US5880129A (en) * 1989-05-19 1999-03-09 The United States Of America As Represented By The Department Of Health And Human Services Methods of inhibiting invasion and metastasis of malignant solid tumors
US5359078A (en) * 1989-05-19 1994-10-25 The United States Of America As Represented By The Department Of Health And Human Services Signal transduction inhibitor compounds
US5498620A (en) * 1989-05-19 1996-03-12 The United States Of America As Represented By The Department Of Health And Human Services Signal transduction inhibitor 1,2,3-triazolo compounds
MA26473A1 (en) 1997-03-01 2004-12-20 Glaxo Group Ltd PHARMACOLOGICALLY ACTIVE COMPOUNDS.
DE19838705A1 (en) 1998-08-26 2000-03-02 Bayer Ag New dihydro- (1,2,3) -triazolo- [4,5-d] pyrimidin-7-ones
JP2015516464A (en) * 2012-05-15 2015-06-11 カルアジア ファーマシューティカルズ，インコーポレイテッド Pyrimidinediamine derivatives as inhibitors of cytoplasmic Hsp90

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1338235A (en) * 1970-12-15 1973-11-21 May & Baker Ltd Azapurinones
US4076711A (en) * 1976-04-05 1978-02-28 Schering Corporation Triazolo [4,5-d]-pyrimidines

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU614297B2 (en) * 1987-07-31 1991-08-29 Chiesi Farmaceutici S.P.A. Pharmaceutical compositions containing trapidil, a process for the preparation thereof and related therapeutic use.
US5166209A (en) * 1989-04-21 1992-11-24 Burroughs Wellcome Co. Pharmacologically active compounds
US5240937A (en) * 1990-04-20 1993-08-31 Burroughs Wellcome Co. Pharmaceutically active triazolopyridine compounds

Also Published As

Publication number Publication date
PT87160B (en) 1992-07-31
NO167919B (en) 1991-09-16
FI881582A0 (en) 1988-04-06
GR3006249T3 (en) 1993-06-21
EP0288431B1 (en) 1992-08-19
DD281190A5 (en) 1990-08-01
FI89359B (en) 1993-06-15
PT87160A (en) 1988-05-01
DK184388A (en) 1988-10-08
IL85947A0 (en) 1988-09-30
DK167681B1 (en) 1993-12-06
MX11012A (en) 1993-12-01
KR880012603A (en) 1988-11-28
NZ224154A (en) 1992-01-29
DK184388D0 (en) 1988-04-06
FI881582A (en) 1988-10-08
JPS63258881A (en) 1988-10-26
EP0288431A1 (en) 1988-10-26
ES2051886T3 (en) 1994-07-01
HUT47577A (en) 1989-03-28
PH26444A (en) 1992-07-15
HU206116B (en) 1992-08-28
ATE79624T1 (en) 1992-09-15
DE3873812D1 (en) 1992-09-24
NO881466L (en) 1988-10-10
ZA882375B (en) 1989-11-29
NO881466D0 (en) 1988-04-06
IL85947A (en) 1993-06-10
AU616880B2 (en) 1991-11-14
NO167919C (en) 1991-12-27
FI89359C (en) 1993-09-27

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