ZA878999B - New pyrole derivatives,their preparation and pharmaceutical compositions which contain them - Google Patents

New pyrole derivatives,their preparation and pharmaceutical compositions which contain them

Info

Publication number
ZA878999B
ZA878999B ZA878999A ZA878999A ZA878999B ZA 878999 B ZA878999 B ZA 878999B ZA 878999 A ZA878999 A ZA 878999A ZA 878999 A ZA878999 A ZA 878999A ZA 878999 B ZA878999 B ZA 878999B
Authority
ZA
South Africa
Prior art keywords
pyrrolidinyl
alkyl
piperidyl
piperazinyl
unsubstituted
Prior art date
Application number
ZA878999A
Other languages
English (en)
Inventor
Jean-Dominique Bourzat
Bourzat Jean-Dominique
Marc Capet
Capet Marc
Claude Cotrel
Cotrel Claude
Richard Labaudiniere
Labaudiniere Richard
Philippe Pitchen
Pitchen Philippe
Gerard Roussel
Roussel Gerard
Original Assignee
Rhone Poulenc Sante
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rhone Poulenc Sante filed Critical Rhone Poulenc Sante
Publication of ZA878999B publication Critical patent/ZA878999B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pain & Pain Management (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Anesthesiology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicinal Preparation (AREA)
  • Polyoxymethylene Polymers And Polymers With Carbon-To-Carbon Bonds (AREA)
  • Indole Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
ZA878999A 1986-12-02 1987-11-30 New pyrole derivatives,their preparation and pharmaceutical compositions which contain them ZA878999B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8616794A FR2607506B1 (fr) 1986-12-02 1986-12-02 Nouveaux derives de l'isoindolinone, leur preparation et les compositions pharmaceutiques qui les contiennent

Publications (1)

Publication Number Publication Date
ZA878999B true ZA878999B (en) 1988-07-27

Family

ID=9341441

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA878999A ZA878999B (en) 1986-12-02 1987-11-30 New pyrole derivatives,their preparation and pharmaceutical compositions which contain them

Country Status (23)

Country Link
US (1) US4898871A (xx)
EP (1) EP0274929B1 (xx)
JP (1) JPS63154686A (xx)
KR (1) KR880007515A (xx)
AT (1) ATE66227T1 (xx)
AU (1) AU594538B2 (xx)
CA (1) CA1298294C (xx)
DE (1) DE3772187D1 (xx)
DK (1) DK630587A (xx)
ES (1) ES2038686T3 (xx)
FI (1) FI84721C (xx)
FR (1) FR2607506B1 (xx)
GR (1) GR3002472T3 (xx)
HU (1) HU199467B (xx)
IL (1) IL84656A (xx)
MA (1) MA21116A1 (xx)
MX (1) MX9557A (xx)
NO (1) NO166183C (xx)
NZ (1) NZ222750A (xx)
OA (1) OA08695A (xx)
PT (1) PT86259B (xx)
SU (5) SU1588280A3 (xx)
ZA (1) ZA878999B (xx)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2607504B1 (fr) * 1986-12-02 1989-01-27 Rhone Poulenc Sante Nouveaux derives de l'isoindolinone, leur preparation et les compositions pharmaceutiques qui les contiennent
FR2607503B1 (fr) * 1986-12-02 1989-02-24 Rhone Poulenc Sante Nouveaux derives de l'isoindolinone, leur preparation et les compositions pharmaceutiques qui les contiennent
AU2018392616B2 (en) 2017-12-21 2023-10-12 Ribon Therapeutics Inc. Quinazolinones as PARP14 inhibitors
CN112138003A (zh) * 2019-06-27 2020-12-29 中山大学 3-正丁基-异吲哚啉-1-酮在镇静、抗惊厥和抗癫痫的药物中的应用
WO2023192782A2 (en) * 2022-03-27 2023-10-05 Board Of Regents, The University Of Texas System Small molecule inhibitors of lanosterol synthase

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR203991A1 (es) * 1972-03-16 1975-11-12 Rhone Poulenc Sa Procedimiento para preparar derivados de(hidroxi-2-amino-3-propoxi)-3-isoindolinona-1
US4000306A (en) * 1973-02-08 1976-12-28 Rhone-Poulenc S.A. Anti-arrhythmic compositions containing isoindoline derivatives
FR2217000B1 (xx) * 1973-02-08 1976-04-09 Rhone Poulenc Ind
AR208414A1 (es) * 1974-11-07 1976-12-27 Rhone Poulenc Ind Procedimiento para obtener nuevos derivados de la((acil-4piperazinil-1)carboniloxi-5 pirrolinona-2)
CS274601B2 (en) * 1983-07-27 1991-09-15 Dainippon Pharmaceutical Co Method of 1,8-naphthyridine derivative production
US4657913A (en) * 1985-04-18 1987-04-14 Warner-Lambert Company Trifluoro- quinoline -3- carboxylic acids and their use as anti-bacterial agents
NZ218773A (en) * 1986-01-06 1990-05-28 Carpibem 3-methyl-2-oxo-1-(substituted phenyl)-naphthyridines and pharmaceutical compositions
FR2607504B1 (fr) * 1986-12-02 1989-01-27 Rhone Poulenc Sante Nouveaux derives de l'isoindolinone, leur preparation et les compositions pharmaceutiques qui les contiennent
FR2607503B1 (fr) * 1986-12-02 1989-02-24 Rhone Poulenc Sante Nouveaux derives de l'isoindolinone, leur preparation et les compositions pharmaceutiques qui les contiennent

Also Published As

Publication number Publication date
FI84721C (fi) 1992-01-10
FI875297A0 (fi) 1987-12-01
SU1627083A3 (ru) 1991-02-07
HU199467B (en) 1990-02-28
MX9557A (es) 1993-10-01
ES2038686T3 (es) 1993-08-01
SU1575937A3 (ru) 1990-06-30
NO166183B (no) 1991-03-04
PT86259B (pt) 1990-11-07
EP0274929B1 (fr) 1991-08-14
FI875297A (fi) 1988-06-03
OA08695A (fr) 1989-03-31
NO875010D0 (no) 1987-12-01
DK630587D0 (da) 1987-12-01
FI84721B (fi) 1991-09-30
SU1588280A3 (ru) 1990-08-23
MA21116A1 (fr) 1988-07-01
AU594538B2 (en) 1990-03-08
US4898871A (en) 1990-02-06
AU8191787A (en) 1988-06-02
JPS63154686A (ja) 1988-06-27
CA1298294C (fr) 1992-03-31
PT86259A (fr) 1988-01-01
KR880007515A (ko) 1988-08-27
NO166183C (no) 1991-06-12
GR3002472T3 (en) 1992-12-30
FR2607506A1 (fr) 1988-06-03
HUT46008A (en) 1988-09-28
DK630587A (da) 1988-06-03
SU1612997A3 (ru) 1990-12-07
IL84656A0 (en) 1988-04-29
NO875010L (no) 1988-06-03
ATE66227T1 (de) 1991-08-15
SU1678202A3 (ru) 1991-09-15
DE3772187D1 (de) 1991-09-19
NZ222750A (en) 1989-10-27
FR2607506B1 (fr) 1989-01-06
IL84656A (en) 1991-12-15
EP0274929A1 (fr) 1988-07-20

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