ZA877471B - 1-tertiary-alkyl-substituted naphthyridine-and quinoline-carboxylic acid antibacterial agents - Google Patents

1-tertiary-alkyl-substituted naphthyridine-and quinoline-carboxylic acid antibacterial agents

Info

Publication number
ZA877471B
ZA877471B ZA877471A ZA877471A ZA877471B ZA 877471 B ZA877471 B ZA 877471B ZA 877471 A ZA877471 A ZA 877471A ZA 877471 A ZA877471 A ZA 877471A ZA 877471 B ZA877471 B ZA 877471B
Authority
ZA
South Africa
Prior art keywords
quinoline
tertiary
alkyl
carboxylic acid
antibacterial agents
Prior art date
Application number
ZA877471A
Other languages
English (en)
Inventor
Di Cesare Pierre
Essiz Munir
Jacquet Jean-Pierre
Remuzon Philippe
Weber Abraham
Bouzard Daniel
Original Assignee
Bristol-Myers Company
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol-Myers Company filed Critical Bristol-Myers Company
Publication of ZA877471B publication Critical patent/ZA877471B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
    • C07D265/28—1,4-Oxazines; Hydrogenated 1,4-oxazines
    • C07D265/30—1,4-Oxazines; Hydrogenated 1,4-oxazines not condensed with other rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C07D215/54—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3
    • C07D215/56—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3 with oxygen atoms in position 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/08—Bridged systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/08—Bridged systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
ZA877471A 1986-10-08 1987-10-05 1-tertiary-alkyl-substituted naphthyridine-and quinoline-carboxylic acid antibacterial agents ZA877471B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US91675286A 1986-10-08 1986-10-08

Publications (1)

Publication Number Publication Date
ZA877471B true ZA877471B (en) 1988-04-05

Family

ID=25437769

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA877471A ZA877471B (en) 1986-10-08 1987-10-05 1-tertiary-alkyl-substituted naphthyridine-and quinoline-carboxylic acid antibacterial agents

Country Status (8)

Country Link
EP (1) EP0288519A4 (xx)
AU (2) AU611400B2 (xx)
DD (2) DD280530A5 (xx)
EG (1) EG18484A (xx)
FI (1) FI883894A (xx)
HU (3) HU911136D0 (xx)
WO (1) WO1988002627A1 (xx)
ZA (1) ZA877471B (xx)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS62108878A (ja) * 1985-11-05 1987-05-20 Kyorin Pharmaceut Co Ltd キノロンカルボン酸誘導体およびその製造方法
CA1336090C (en) * 1988-08-31 1995-06-27 Isao Hayakawa Spiro-substituted cyclic amines of quinolone derivatives
US5286723A (en) * 1988-08-31 1994-02-15 Daiichi Seiyaku Co., Ltd. Spiro compound
CA1332605C (en) * 1988-10-03 1994-10-18 Yasuhiro Nishitani Pyridonecarboxylic acids
US5262417A (en) * 1988-12-06 1993-11-16 The Upjohn Company Antibacterial quinolone compounds
US4916141A (en) * 1989-03-28 1990-04-10 Warner-Lambert Company (S)-7-(3-amino-1-pyrrolidinyl)-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-1,8-naphthyridine-3-carboxylic acid
CA2013720A1 (en) * 1989-04-18 1990-10-18 Yasuo Ito Thiazetoquinoline-3-carboxylic acid derivative, method for preparation thereof, and a pharmaceutical composition comprising the same
US5342846A (en) * 1990-12-05 1994-08-30 Synphar Laboratories, Inc. 7-substituted-6-fluoro-1,4-dihydro-4-oxo-quinoline-3-carboxylic acid compounds and 7-(substituted triazolyl pyrrolidin-1-yl) 4-oxoquinoline-3-carboxylic acid derivatives useful as antibacterial agents
ID16655A (id) * 1996-04-24 1997-10-30 Daiichi Seiyaku Co Turunan-turunan sikloalkilaminometilpirolidina
RU2221782C2 (ru) 1996-08-28 2004-01-20 Дзе Проктер Энд Гэмбл Компани Замещенные циклические аминовые ингибиторы металлопротеаз
US6872742B2 (en) 1996-08-28 2005-03-29 The Procter & Gamble Company Substituted cyclic amine metalloprotease inhibitors
JP2001513484A (ja) 1997-07-31 2001-09-04 ザ プロクター アンド ギャンブル カンパニー 非環式メタロプロテアーゼ阻害剤
HUP0202199A2 (en) 1999-03-03 2002-10-28 Procter & Gamble Alkenyl- and alkynyl-containing metalloprotease inhibitors
SE0003795D0 (sv) 2000-10-20 2000-10-20 Astrazeneca Ab Pharmaceutically useful compounds
MXPA05002621A (es) * 2002-09-10 2005-05-05 Pfizer Prod Inc Compuestos diazabiciclos utiles en el tratamiento de transtornos del sistema nervioso central y otros trastornos.
WO2006081178A2 (en) * 2005-01-25 2006-08-03 Glaxo Group Limited Antibacterial agents

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB937183A (en) * 1960-02-17 1963-09-18 Lepetit Spa 3,8-diazabicyclo-[3,2,1]-octanes
CH408036A (de) * 1960-02-17 1966-02-28 Lepetit Spa Verfahren zur Herstellung von 3,8-Diazabicyclo-(3,2,1)-octan-2,4-dionen
DE2808070A1 (de) * 1978-02-24 1979-08-30 Bayer Ag Verfahren zur herstellung von 4-pyridon-3-carbonsaeuren und/oder deren derivaten
GB2093018B (en) * 1979-08-22 1984-09-12 Kyorin Seiyaku Kk 6,8-difluoro-quinoline carboxylic acid derivatives
JPS5649382A (en) * 1979-09-28 1981-05-02 Dainippon Pharmaceut Co Ltd 6-fluoro-7-cyclic amino-1,8-naphthylidine derivative and its salt
US4665079A (en) * 1984-02-17 1987-05-12 Warner-Lambert Company Antibacterial agents
US4571396A (en) * 1984-04-16 1986-02-18 Warner-Lambert Company Antibacterial agents
DE3509546A1 (de) * 1985-03-16 1986-09-25 Bayer Ag, 5090 Leverkusen 7-amino-1-(subst.cyclopropyl)-1,4-dihydro-4-oxo-3-chinolincarbonsaeuren, verfahren zu ihrer herstellung sowie diese enthaltende antibakterielle mittel
US4578473A (en) * 1985-04-15 1986-03-25 Warner-Lambert Company Process for quinoline-3-carboxylic acid antibacterial agents
US4772706A (en) * 1986-01-13 1988-09-20 Warner-Lambert Company Process for quinoline-3-carboxylic acid antibacterial agents
DE3601567A1 (de) * 1986-01-21 1987-07-23 Bayer Ag 7-(azabicycloalkyl)-chinoloncarbonsaeure- und -naphthyridon-carbonsaeure-derivate

Also Published As

Publication number Publication date
DD266354A5 (de) 1989-03-29
WO1988002627A1 (en) 1988-04-21
AU7632691A (en) 1991-08-08
EP0288519A4 (en) 1992-04-15
HU203753B (en) 1991-09-30
FI883894A0 (fi) 1988-08-23
HU911136D0 (en) 1991-10-28
EP0288519A1 (en) 1988-11-02
HUT52500A (en) 1990-07-28
EG18484A (en) 1993-04-30
AU611400B2 (en) 1991-06-13
AU8158187A (en) 1988-05-06
DD280530A5 (de) 1990-07-11
FI883894A (fi) 1988-08-23

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