HUT52500A - Process for producing antibacterial 1-terc-alkyl-substituted naphtiridine- and quinoline-carboxylic acids and pharmaceutical compositions containing them as active components - Google Patents

Process for producing antibacterial 1-terc-alkyl-substituted naphtiridine- and quinoline-carboxylic acids and pharmaceutical compositions containing them as active components

Info

Publication number
HUT52500A
HUT52500A HU875686A HU568787A HUT52500A HU T52500 A HUT52500 A HU T52500A HU 875686 A HU875686 A HU 875686A HU 568787 A HU568787 A HU 568787A HU T52500 A HUT52500 A HU T52500A
Authority
HU
Hungary
Prior art keywords
naphtiridine
terc
quinoline
substituted
alkyl
Prior art date
Application number
HU875686A
Other languages
Hungarian (hu)
Inventor
Abraham Weber
Daniel Bouzard
Munir Essiz
Cesare Pierre Di
Jacquet
Phillippe Remuzon
Original Assignee
Bristol Myers Squibb Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Squibb Co filed Critical Bristol Myers Squibb Co
Publication of HUT52500A publication Critical patent/HUT52500A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
    • C07D265/28—1,4-Oxazines; Hydrogenated 1,4-oxazines
    • C07D265/30—1,4-Oxazines; Hydrogenated 1,4-oxazines not condensed with other rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C07D215/54—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3
    • C07D215/56—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3 with oxygen atoms in position 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/08—Bridged systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/08—Bridged systems
HU875686A 1986-10-08 1987-10-08 Process for producing antibacterial 1-terc-alkyl-substituted naphtiridine- and quinoline-carboxylic acids and pharmaceutical compositions containing them as active components HUT52500A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US91675286A 1986-10-08 1986-10-08

Publications (1)

Publication Number Publication Date
HUT52500A true HUT52500A (en) 1990-07-28

Family

ID=25437769

Family Applications (3)

Application Number Title Priority Date Filing Date
HU875686A HUT52500A (en) 1986-10-08 1987-10-08 Process for producing antibacterial 1-terc-alkyl-substituted naphtiridine- and quinoline-carboxylic acids and pharmaceutical compositions containing them as active components
HU875686A HU203753B (en) 1986-10-08 1987-10-08 Process for producing 1-terc-alkyl-substituted naphtiridine and quinoline-carboxylic acids and pharmaceutical compositions contianing them
HU911136A HU911136D0 (en) 1986-10-08 1987-10-08 Process for producing 1-tertiary-alkyl-substituted naphtyridine- and quinoline-carbonic acid derivatives and intermediate products

Family Applications After (2)

Application Number Title Priority Date Filing Date
HU875686A HU203753B (en) 1986-10-08 1987-10-08 Process for producing 1-terc-alkyl-substituted naphtiridine and quinoline-carboxylic acids and pharmaceutical compositions contianing them
HU911136A HU911136D0 (en) 1986-10-08 1987-10-08 Process for producing 1-tertiary-alkyl-substituted naphtyridine- and quinoline-carbonic acid derivatives and intermediate products

Country Status (8)

Country Link
EP (1) EP0288519A4 (en)
AU (2) AU611400B2 (en)
DD (2) DD266354A5 (en)
EG (1) EG18484A (en)
FI (1) FI883894A0 (en)
HU (3) HUT52500A (en)
WO (1) WO1988002627A1 (en)
ZA (1) ZA877471B (en)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS62108878A (en) * 1985-11-05 1987-05-20 Kyorin Pharmaceut Co Ltd Quinolonecarboxylic acid derivative and production thereof
CA1336090C (en) * 1988-08-31 1995-06-27 Isao Hayakawa Spiro-substituted cyclic amines of quinolone derivatives
US5286723A (en) * 1988-08-31 1994-02-15 Daiichi Seiyaku Co., Ltd. Spiro compound
CA1332605C (en) * 1988-10-03 1994-10-18 Yasuhiro Nishitani Pyridonecarboxylic acids
US5262417A (en) * 1988-12-06 1993-11-16 The Upjohn Company Antibacterial quinolone compounds
US4916141A (en) * 1989-03-28 1990-04-10 Warner-Lambert Company (S)-7-(3-amino-1-pyrrolidinyl)-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-1,8-naphthyridine-3-carboxylic acid
AU618460B2 (en) * 1989-04-18 1991-12-19 Hokuriku Pharmaceutical Co. Ltd. Thiazetoquinoline-3-carboxylic acid derivative, method for preparation thereof, and a pharmaceutical composition comprising the same
US5342846A (en) * 1990-12-05 1994-08-30 Synphar Laboratories, Inc. 7-substituted-6-fluoro-1,4-dihydro-4-oxo-quinoline-3-carboxylic acid compounds and 7-(substituted triazolyl pyrrolidin-1-yl) 4-oxoquinoline-3-carboxylic acid derivatives useful as antibacterial agents
TW425394B (en) * 1996-04-24 2001-03-11 Daiichi Seiyaku Co Antimicrobial quinolone derivatives having 3-(N-cycloalkyl) aminomethylpyrrolidine group
US6872742B2 (en) 1996-08-28 2005-03-29 The Procter & Gamble Company Substituted cyclic amine metalloprotease inhibitors
PL331802A1 (en) 1996-08-28 1999-08-02 Procter & Gamble Substituted cyclic amines as metaloprotease inhibitors
BR9810841A (en) 1997-07-31 2001-07-10 Procter & Gamble Alicyclic metalloprotease inhibitors
US6197770B1 (en) 1999-03-03 2001-03-06 The Procter & Gamble Co. Alkenyl- and alkynl-containing metalloprotease inhibitors
SE0003795D0 (en) 2000-10-20 2000-10-20 Astrazeneca Ab Pharmaceutically useful compounds
BR0314201A (en) 2002-09-10 2005-07-12 Pfizer Prod Inc Diazabicyclic Compounds Useful in the Treatment of CNS Diseases and Other Disorders
US7648980B2 (en) * 2005-01-25 2010-01-19 Glaxo Group Limited Antibacterial agents

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH408036A (en) * 1960-02-17 1966-02-28 Lepetit Spa Process for the preparation of 3,8-diazabicyclo- (3,2,1) -octane-2,4-dione
GB937183A (en) * 1960-02-17 1963-09-18 Lepetit Spa 3,8-diazabicyclo-[3,2,1]-octanes
DE2808070A1 (en) * 1978-02-24 1979-08-30 Bayer Ag PROCESS FOR THE PRODUCTION OF 4-PYRIDONE-3-CARBONIC ACIDS AND / OR DERIVATIVES
GB2093018B (en) * 1979-08-22 1984-09-12 Kyorin Seiyaku Kk 6,8-difluoro-quinoline carboxylic acid derivatives
JPS5649382A (en) * 1979-09-28 1981-05-02 Dainippon Pharmaceut Co Ltd 6-fluoro-7-cyclic amino-1,8-naphthylidine derivative and its salt
US4665079A (en) * 1984-02-17 1987-05-12 Warner-Lambert Company Antibacterial agents
US4571396A (en) * 1984-04-16 1986-02-18 Warner-Lambert Company Antibacterial agents
DE3509546A1 (en) * 1985-03-16 1986-09-25 Bayer Ag, 5090 Leverkusen 7-AMINO-1- (SUBST.CYCLOPROPYL) -1,4-DIHYDRO-4-OXO-3-CHINOLINE CARBONIC ACIDS, METHOD FOR THE PRODUCTION THEREOF AND THE ANTIBACTERIAL AGENTS CONTAINING THEM
US4578473A (en) * 1985-04-15 1986-03-25 Warner-Lambert Company Process for quinoline-3-carboxylic acid antibacterial agents
US4772706A (en) * 1986-01-13 1988-09-20 Warner-Lambert Company Process for quinoline-3-carboxylic acid antibacterial agents
DE3601567A1 (en) * 1986-01-21 1987-07-23 Bayer Ag 7- (AZABICYCLOALKYL) -CHINOLONCARBONIC ACID AND -NAPHTHYRIDON-CARBONIC ACID DERIVATIVES

Also Published As

Publication number Publication date
HU203753B (en) 1991-09-30
FI883894A (en) 1988-08-23
DD266354A5 (en) 1989-03-29
WO1988002627A1 (en) 1988-04-21
EG18484A (en) 1993-04-30
AU611400B2 (en) 1991-06-13
DD280530A5 (en) 1990-07-11
EP0288519A4 (en) 1992-04-15
EP0288519A1 (en) 1988-11-02
ZA877471B (en) 1988-04-05
HU911136D0 (en) 1991-10-28
FI883894A0 (en) 1988-08-23
AU7632691A (en) 1991-08-08
AU8158187A (en) 1988-05-06

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