ZA876970B - Assay method and diagnostic system for a marker of abnormal lipid metabolism - Google Patents
Assay method and diagnostic system for a marker of abnormal lipid metabolismInfo
- Publication number
- ZA876970B ZA876970B ZA876970A ZA876970A ZA876970B ZA 876970 B ZA876970 B ZA 876970B ZA 876970 A ZA876970 A ZA 876970A ZA 876970 A ZA876970 A ZA 876970A ZA 876970 B ZA876970 B ZA 876970B
- Authority
- ZA
- South Africa
- Prior art keywords
- marker
- assay method
- diagnostic system
- lipid metabolism
- abnormal lipid
- Prior art date
Links
- 230000002159 abnormal effect Effects 0.000 title 1
- 238000003556 assay Methods 0.000 title 1
- 230000037356 lipid metabolism Effects 0.000 title 1
- 239000003550 marker Substances 0.000 title 1
- 238000000034 method Methods 0.000 abstract 2
- 102000005666 Apolipoprotein A-I Human genes 0.000 abstract 1
- 108010059886 Apolipoprotein A-I Proteins 0.000 abstract 1
- 102000006991 Apolipoprotein B-100 Human genes 0.000 abstract 1
- 108010008150 Apolipoprotein B-100 Proteins 0.000 abstract 1
- 238000002965 ELISA Methods 0.000 abstract 1
- 210000004408 hybridoma Anatomy 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/92—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving lipids, e.g. cholesterol, lipoproteins, or their receptors
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/04—Endocrine or metabolic disorders
- G01N2800/044—Hyperlipemia or hypolipemia, e.g. dyslipidaemia, obesity
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/81—Packaged device or kit
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/8215—Microorganisms
- Y10S435/948—Microorganisms using viruses or cell lines
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
- Y10S530/808—Materials and products related to genetic engineering or hybrid or fused cell technology, e.g. hybridoma, monoclonal products
- Y10S530/809—Fused cells, e.g. hybridoma
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Engineering & Computer Science (AREA)
- Hematology (AREA)
- Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Urology & Nephrology (AREA)
- Immunology (AREA)
- Biochemistry (AREA)
- Cell Biology (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Endocrinology (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Peptides Or Proteins (AREA)
- Measuring And Recording Apparatus For Diagnosis (AREA)
- Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
- Fats And Perfumes (AREA)
- Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
- Measuring Pulse, Heart Rate, Blood Pressure Or Blood Flow (AREA)
- Saccharide Compounds (AREA)
- Arrangements For Transmission Of Measured Signals (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US06/913,140 US4828986A (en) | 1986-09-29 | 1986-09-29 | Assay method and diagnostic system for determining the ratio of APO B-100 to APO A-I in a blood sample |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA876970B true ZA876970B (en) | 1988-03-21 |
Family
ID=25432962
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA876970A ZA876970B (en) | 1986-09-29 | 1987-09-16 | Assay method and diagnostic system for a marker of abnormal lipid metabolism |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US4828986A (da) |
| EP (1) | EP0262854B1 (da) |
| JP (1) | JP2656774B2 (da) |
| AT (1) | ATE85435T1 (da) |
| AU (1) | AU611096B2 (da) |
| CA (1) | CA1285869C (da) |
| DE (1) | DE3783991T2 (da) |
| DK (1) | DK173724B1 (da) |
| ES (1) | ES2053555T3 (da) |
| FI (1) | FI89214C (da) |
| GR (1) | GR3008027T3 (da) |
| IE (1) | IE60119B1 (da) |
| IL (1) | IL83938A (da) |
| NO (1) | NO173902C (da) |
| NZ (1) | NZ221941A (da) |
| PT (1) | PT85827B (da) |
| ZA (1) | ZA876970B (da) |
Families Citing this family (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0257778B1 (en) * | 1986-08-06 | 1995-03-22 | Scripps Clinic And Research Foundation | Apolipoprotein b-specific monoclonal antibodies produced by two novel hybridomas |
| DE3734015A1 (de) * | 1987-10-08 | 1989-04-20 | Behringwerke Ag | Diagnostisches mittel und verfahren zur bestimmung von apolipoprotein b |
| AU621575B2 (en) * | 1987-11-02 | 1992-03-19 | Scripps Clinic And Research Foundation | Diagnostic methods and systems for quantifying apo ai |
| US5759774A (en) * | 1988-05-18 | 1998-06-02 | Cobe Laboratories, Inc. | Method of detecting circulating antibody types using dried or lyophilized cells |
| US5183738A (en) * | 1988-09-29 | 1993-02-02 | Japan Immuno Research Laboratories Co., Ltd. | Kit for the detection of denatured lipoproteins |
| US5179008A (en) * | 1989-02-09 | 1993-01-12 | Wisconsin Alumni Research Foundation | Hybridoma and monoclonal antibody to FHAP |
| US5473039A (en) * | 1989-08-18 | 1995-12-05 | The Scripps Research Institute | Polypeptide analogs of apolipoprotein E, diagnostic systems and methods using the analogs |
| US5168045A (en) * | 1989-08-18 | 1992-12-01 | The Scripps Research Institute | Diagnostic systems and methods using polypeptide analogs of apolipoprotein e |
| AU662885B2 (en) * | 1990-06-07 | 1995-09-21 | Scripps Research Institute, The | APO AI polypeptides, antibodies, and immunoassays |
| WO1992009893A1 (en) * | 1990-11-29 | 1992-06-11 | Carbaugh John E | DIAGNOSTIC AND THERAPEUTIC COMPOSITIONS AND METHODS FOR LIPOPROTEIN(a) |
| WO1992010760A1 (en) * | 1990-11-30 | 1992-06-25 | Monoclonetics International, Incorporated | Methods for the diagnosis of chronic lower back and cervical pain |
| US5844097A (en) * | 1990-11-30 | 1998-12-01 | Monoclonetics International, Inc. | Methods for the diagnosis of peripheral nerve damage |
| US5408038A (en) * | 1991-10-09 | 1995-04-18 | The Scripps Research Institute | Nonnatural apolipoprotein B-100 peptides and apolipoprotein B-100-apolipoprotein A-I fusion peptides |
| CA2145389A1 (en) * | 1992-09-24 | 1994-03-31 | Laszlo Varady | Quantitative measurement of ldl |
| US6107045A (en) * | 1994-06-30 | 2000-08-22 | Oklahoma Medical Research Foundation | Antibodies to lipoproteins and apolipoproteins and methods of use thereof |
| US5994061A (en) * | 1995-09-29 | 1999-11-30 | Queen's University At Kingston | DNA constructs and methods for screening for increased expression of human apo AI gene |
| US5741647A (en) * | 1996-02-16 | 1998-04-21 | Tam; Joseph Wing On | Flow through nucleic acid hybridisation uses thereof and a device thereof |
| US6248539B1 (en) * | 1997-09-05 | 2001-06-19 | The Scripps Research Institute | Porous semiconductor-based optical interferometric sensor |
| US6309844B1 (en) | 1997-10-15 | 2001-10-30 | Fujirebio Inc. | Anti-apo-B-48 monoclonal antibody, hybridoma producing the same, and method for measuring apo-B-48 using the same |
| AT5044U1 (de) * | 2001-05-10 | 2002-02-25 | Medsystems Diagnostics Gmbh | Quantitativer einschritt immuntest in lyophilisierter form |
| KR20040025931A (ko) * | 2001-07-12 | 2004-03-26 | 교와 메덱스 가부시키가이샤 | 변성 리포단백질의 정량법, 변성 리포단백질의 정량용시약, 순환기 질환의 검출방법 및 순환기 질환의 검출시약 |
| ATE427490T1 (de) * | 2003-10-15 | 2009-04-15 | Sekisui Medical Co Ltd | Verfahren zur probenvorbehandlung sowie immunologisches testverfahren unter verwendung davon |
| US7781171B2 (en) | 2003-10-15 | 2010-08-24 | Daiichi Pure Chemicals Co., Ltd. | Mehod of pretreating sample and immunological assay method using the same |
| US7521248B2 (en) * | 2007-04-20 | 2009-04-21 | Atherotech, Inc. | Apo B measurement system and method |
| JP6507423B2 (ja) | 2011-11-11 | 2019-05-08 | アクシス‐シールド エーエスＡｘｉｓ−Ｓｈｉｅｌｄ ＡＳ | 血液サンプルのアッセイ法 |
| CN118047854B (zh) * | 2024-02-26 | 2024-08-02 | 武汉鹰达生物科技有限公司 | 一种人载脂蛋白a-i的分离纯化方法 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2061282B (en) * | 1979-10-22 | 1983-03-30 | Symphar Sa | Method for the clinical separation of a-and lipoproteins and kit for carrying out this method |
| US4376110A (en) * | 1980-08-04 | 1983-03-08 | Hybritech, Incorporated | Immunometric assays using monoclonal antibodies |
| JPS60193926A (ja) * | 1984-03-15 | 1985-10-02 | Tokyo Daigaku | 単クローン性抗ヒトアポリポ蛋白質ｂ１００抗体 |
| JPS60253871A (ja) * | 1984-05-30 | 1985-12-14 | Nippon Koutai Kenkyusho:Kk | 抗アポａ−１抗体 |
| EP0209543A4 (en) * | 1984-12-31 | 1989-07-11 | Internat Genetic Engineering I | FRAGMENTS OF HUMAN APOLIPOPROTEINS PEPTIDES, TYPE-SPECIFIC ANTIBODIES AND METHODS OF USE. |
| US4677057A (en) * | 1985-03-11 | 1987-06-30 | Scripps Clinic And Research Foundation | Diagnostic assay for the presence of apolipoproteins associated with plasma high density lipoproteins |
-
1986
- 1986-09-29 US US06/913,140 patent/US4828986A/en not_active Expired - Lifetime
-
1987
- 1987-09-16 ZA ZA876970A patent/ZA876970B/xx unknown
- 1987-09-17 IL IL83938A patent/IL83938A/xx not_active IP Right Cessation
- 1987-09-22 EP EP87308392A patent/EP0262854B1/en not_active Expired - Lifetime
- 1987-09-22 DE DE8787308392T patent/DE3783991T2/de not_active Expired - Lifetime
- 1987-09-22 ES ES87308392T patent/ES2053555T3/es not_active Expired - Lifetime
- 1987-09-22 AT AT87308392T patent/ATE85435T1/de not_active IP Right Cessation
- 1987-09-25 NZ NZ221941A patent/NZ221941A/xx unknown
- 1987-09-28 NO NO874056A patent/NO173902C/no unknown
- 1987-09-28 CA CA000547941A patent/CA1285869C/en not_active Expired - Lifetime
- 1987-09-28 IE IE260587A patent/IE60119B1/en not_active IP Right Cessation
- 1987-09-28 FI FI874253A patent/FI89214C/fi not_active IP Right Cessation
- 1987-09-28 DK DK198705092A patent/DK173724B1/da not_active IP Right Cessation
- 1987-09-28 AU AU79028/87A patent/AU611096B2/en not_active Expired
- 1987-09-29 PT PT85827A patent/PT85827B/pt unknown
- 1987-09-29 JP JP62245737A patent/JP2656774B2/ja not_active Expired - Lifetime
-
1993
- 1993-04-30 GR GR920403215T patent/GR3008027T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| IL83938A (en) | 1991-12-15 |
| FI89214C (fi) | 1993-08-25 |
| EP0262854A3 (en) | 1989-12-06 |
| NO874056D0 (no) | 1987-09-28 |
| ATE85435T1 (de) | 1993-02-15 |
| DK509287D0 (da) | 1987-09-28 |
| DK173724B1 (da) | 2001-07-30 |
| FI874253L (fi) | 1988-03-30 |
| IE60119B1 (en) | 1994-06-01 |
| IL83938A0 (en) | 1988-02-29 |
| NZ221941A (en) | 1989-05-29 |
| ES2053555T3 (es) | 1994-08-01 |
| US4828986A (en) | 1989-05-09 |
| GR3008027T3 (da) | 1993-09-30 |
| JPS63277968A (ja) | 1988-11-15 |
| IE872605L (en) | 1988-03-29 |
| JP2656774B2 (ja) | 1997-09-24 |
| EP0262854B1 (en) | 1993-02-03 |
| AU611096B2 (en) | 1991-06-06 |
| FI89214B (fi) | 1993-05-14 |
| DE3783991T2 (de) | 1993-06-09 |
| AU7902887A (en) | 1988-03-31 |
| DE3783991D1 (de) | 1993-03-18 |
| FI874253A0 (fi) | 1987-09-28 |
| NO874056L (no) | 1988-03-30 |
| NO173902B (no) | 1993-11-08 |
| EP0262854A2 (en) | 1988-04-06 |
| NO173902C (no) | 1994-02-16 |
| DK509287A (da) | 1988-03-30 |
| PT85827A (en) | 1987-10-01 |
| CA1285869C (en) | 1991-07-09 |
| PT85827B (pt) | 1990-08-31 |
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