ZA874046B - Antiallergy and antiinflammatory agents - Google Patents

Antiallergy and antiinflammatory agents

Info

Publication number
ZA874046B
ZA874046B ZA874046A ZA874046A ZA874046B ZA 874046 B ZA874046 B ZA 874046B ZA 874046 A ZA874046 A ZA 874046A ZA 874046 A ZA874046 A ZA 874046A ZA 874046 B ZA874046 B ZA 874046B
Authority
ZA
South Africa
Prior art keywords
antiallergy
antiinflammatory agents
alkyl
hydrogen
alkanoyl
Prior art date
Application number
ZA874046A
Other languages
English (en)
Inventor
Yoshihiko Kitaura
Kitaura Yoshihiko
Nobuko Asai
Asai Nobuko
Fumitaka Ito
Ito Fumitaka
Rodney William Stevens
William Stevens Rodney
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of ZA874046B publication Critical patent/ZA874046B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/52—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings condensed with carbocyclic rings or ring systems
    • C07D263/54—Benzoxazoles; Hydrogenated benzoxazoles
    • C07D263/58—Benzoxazoles; Hydrogenated benzoxazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/52—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings condensed with carbocyclic rings or ring systems
    • C07D263/54—Benzoxazoles; Hydrogenated benzoxazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
    • C07D209/32—Oxygen atoms
    • C07D209/34—Oxygen atoms in position 2
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/24—Benzimidazoles; Hydrogenated benzimidazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • C07D235/26—Oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/60—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
    • C07D277/62—Benzothiazoles
    • C07D277/68—Benzothiazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Pulmonology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • External Artificial Organs (AREA)
  • Fats And Perfumes (AREA)
  • Indole Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Non-Silver Salt Photosensitive Materials And Non-Silver Salt Photography (AREA)
  • Hydrogenated Pyridines (AREA)
ZA874046A 1986-06-09 1987-06-05 Antiallergy and antiinflammatory agents ZA874046B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP13347086 1986-06-09

Publications (1)

Publication Number Publication Date
ZA874046B true ZA874046B (en) 1989-01-25

Family

ID=15105525

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA874046A ZA874046B (en) 1986-06-09 1987-06-05 Antiallergy and antiinflammatory agents

Country Status (21)

Country Link
EP (1) EP0249407B1 (zh)
JP (1) JPH0623199B2 (zh)
KR (1) KR900000552B1 (zh)
CN (1) CN1015334B (zh)
AT (1) ATE60596T1 (zh)
AU (1) AU586337B2 (zh)
CA (1) CA1305151C (zh)
DD (1) DD265141A5 (zh)
DE (1) DE3767778D1 (zh)
DK (1) DK288287A (zh)
ES (1) ES2031892T3 (zh)
FI (1) FI87924C (zh)
GR (1) GR3001584T3 (zh)
HU (1) HU198451B (zh)
IE (1) IE60015B1 (zh)
NO (1) NO168246C (zh)
PL (1) PL150631B1 (zh)
PT (1) PT85035B (zh)
SU (1) SU1757464A3 (zh)
YU (1) YU45423B (zh)
ZA (1) ZA874046B (zh)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4720297A (en) * 1985-09-27 1988-01-19 Sumitomo Chemical Company, Limited Benzothiazolones, and their production and use as herbicides
JPH0283376A (ja) * 1988-09-19 1990-03-23 Pfizer Pharmaceut Co Ltd ベンゾオキサゾロン誘導体および抗アレルギー又は抗炎症組成物
IL93473A0 (en) * 1989-02-28 1990-11-29 Pfizer Antiinflammatory benzoxazolones
JPH0678327B2 (ja) * 1989-07-20 1994-10-05 ファイザー製薬株式会社 ４，５，６，７，―四置換ベンゾオキサゾロン類
JPH0729998B2 (ja) * 1990-01-22 1995-04-05 ファイザー製薬株式会社 新規ベンゾキノン化合物およびその組成物
AU6966696A (en) * 1995-10-05 1997-04-28 Warner-Lambert Company Method for treating and preventing inflammation and atherosclerosis
US5972980A (en) * 1995-10-05 1999-10-26 Warner-Lambert Company Method for treating and preventing inflammation and atherosclerosis
US6001866A (en) * 1995-10-05 1999-12-14 Warner-Lambert Company Method for treating and preventing inflammation and atherosclerosis
US7186745B2 (en) 2001-03-06 2007-03-06 Astrazeneca Ab Indolone derivatives having vascular damaging activity
DE10210779A1 (de) * 2002-03-12 2003-10-09 Merck Patent Gmbh Cyclische Amide
TW200508197A (en) * 2003-03-31 2005-03-01 Ucb Sa Indolone-acetamide derivatives, processes for preparing them and their uses
US7270805B1 (en) * 2006-03-30 2007-09-18 Conopco, Inc. Skin lightening agents, compositions and methods
WO2010090680A1 (en) * 2008-12-15 2010-08-12 Wyeth Llc Substituted oxindole cb2 agonists
US9199967B2 (en) * 2011-08-18 2015-12-01 Dr. Reddy's Laboratories Ltd. Substituted heterocyclic amine compounds as cholestryl ester-transfer protein (CETP) inhibitors
SG11201407566VA (en) * 2012-05-21 2014-12-30 Wolff August Gmbh & Co Kg Arzneimittel Dr Novel 1,3-benzoxazol-2(3h)-ones and their use as medicaments and cosmetics
EP3932395A1 (en) * 2020-07-03 2022-01-05 Dr. August Wolff GmbH & Co. KG Arzneimittel Stable emulsion containing an active pharmaceutical ingredient based on n(3-methyl-2-oxo-2,3-dihydrobenzo[d]oxazol-5-yl)dodecanamide, production and use

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5663972A (en) * 1979-10-30 1981-05-30 Tetsujirou Masuko Preparation of novel benzothiazolone derivative containing novel heterocyclic quaternary salt
DE3017977A1 (de) * 1980-05-10 1981-11-19 Dr. Karl Thomae Gmbh, 7950 Biberach Neue substituierte 2(3h)-benzothiazolone
DE3042481A1 (de) * 1980-11-11 1982-06-16 A. Nattermann & Cie GmbH, 5000 Köln (omega)-(2-oxo-benzazolinyl)-alkansaeure-derivate, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische praeparate
GB8325370D0 (en) * 1983-09-22 1983-10-26 Fujisawa Pharmaceutical Co Benzoxazoline and benzothiazoline derivatives
US4569942A (en) * 1984-05-04 1986-02-11 Pfizer Inc. N,3-Disubstituted 2-oxindole-1-carboxamides as analgesic and antiinflammatory agents
US4690943A (en) * 1984-09-19 1987-09-01 Pfizer Inc. Analgesic and antiinflammatory 1,3-diacyl-2-oxindole compounds

Also Published As

Publication number Publication date
CN1015334B (zh) 1992-01-29
DK288287D0 (da) 1987-06-04
ATE60596T1 (de) 1991-02-15
FI872555A (fi) 1987-12-10
KR900000552B1 (ko) 1990-01-31
CA1305151C (en) 1992-07-14
CN87104099A (zh) 1988-02-10
EP0249407A2 (en) 1987-12-16
EP0249407A3 (en) 1988-10-19
PL266132A1 (en) 1988-06-23
PL150631B1 (en) 1990-06-30
YU45423B (en) 1992-05-28
AU7387887A (en) 1987-12-10
NO168246B (no) 1991-10-21
PT85035B (pt) 1990-03-08
GR3001584T3 (en) 1992-11-23
NO872382L (no) 1987-12-10
IE871505L (en) 1987-12-09
DD265141A5 (de) 1989-02-22
NO168246C (no) 1992-01-29
ES2031892T3 (es) 1996-07-16
NO872382D0 (no) 1987-06-05
PT85035A (en) 1987-07-01
HU198451B (en) 1989-10-30
DE3767778D1 (de) 1991-03-07
IE60015B1 (en) 1994-05-18
FI87924B (fi) 1992-11-30
DK288287A (da) 1987-12-10
KR880000413A (ko) 1988-03-25
SU1757464A3 (ru) 1992-08-23
EP0249407B1 (en) 1991-01-30
HUT48209A (en) 1989-05-29
JPS63107958A (ja) 1988-05-12
JPH0623199B2 (ja) 1994-03-30
FI872555A0 (fi) 1987-06-08
AU586337B2 (en) 1989-07-06
YU104987A (en) 1988-08-31
FI87924C (fi) 1993-03-10

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