ZA868269B - Dipamine-beta-hydroxylase inhibitors - Google Patents
Dipamine-beta-hydroxylase inhibitorsInfo
- Publication number
- ZA868269B ZA868269B ZA868269A ZA868269A ZA868269B ZA 868269 B ZA868269 B ZA 868269B ZA 868269 A ZA868269 A ZA 868269A ZA 868269 A ZA868269 A ZA 868269A ZA 868269 B ZA868269 B ZA 868269B
- Authority
- ZA
- South Africa
- Prior art keywords
- dipamine
- beta
- hydroxylase inhibitors
- hydroxylase
- inhibitors
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/04—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D233/28—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/30—Oxygen or sulfur atoms
- C07D233/42—Sulfur atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C255/00—Carboxylic acid nitriles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C335/00—Thioureas, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
- C07C335/04—Derivatives of thiourea
- C07C335/16—Derivatives of thiourea having nitrogen atoms of thiourea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
- C07C335/20—Derivatives of thiourea having nitrogen atoms of thiourea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton being further substituted by nitrogen atoms, not being part of nitro or nitroso groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/84—Sulfur atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US06/793,512 US4719223A (en) | 1985-10-31 | 1985-10-31 | Imidazolethiol dopamine-beta-hydroxylase inhibitors |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA868269B true ZA868269B (en) | 1987-07-29 |
Family
ID=25160082
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA868269A ZA868269B (en) | 1985-10-31 | 1986-10-30 | Dipamine-beta-hydroxylase inhibitors |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US4719223A (fi) |
| EP (1) | EP0221778A3 (fi) |
| JP (1) | JPS62108815A (fi) |
| KR (1) | KR870003994A (fi) |
| CN (1) | CN86107151A (fi) |
| AU (1) | AU598485B2 (fi) |
| DK (1) | DK515786A (fi) |
| FI (1) | FI864431A (fi) |
| HU (1) | HU197563B (fi) |
| NO (1) | NO864337L (fi) |
| NZ (1) | NZ218098A (fi) |
| PH (1) | PH21776A (fi) |
| PT (1) | PT83628B (fi) |
| ZA (1) | ZA868269B (fi) |
| ZW (1) | ZW21586A1 (fi) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4743613A (en) * | 1986-04-08 | 1988-05-10 | Smithkline Beckman Corporation | Ester prodrugs of dopamine-β-hydroxylase, inhibitors, composition containing them, and method of using them to inhibit dopamine-β-hydroxylase activity |
| US5057613A (en) * | 1986-05-06 | 1991-10-15 | Merrell Dow Pharmaceuticals | Novel thione dopamine beta hydroxylase inhibitors |
| US4859779A (en) * | 1987-03-24 | 1989-08-22 | Smithkline Beckman Corporation | Dopamine-β-hydroxylase inhibitors |
| US4835154A (en) * | 1987-06-01 | 1989-05-30 | Smithkline Beckman Corporation | 1-aralykyl-5-piperazinylmethyl-2-mercaptoimidazoles and 2-alkylthioimidazoles and their use as dopamine-βhydroxylase inhibitors |
| US4882348A (en) * | 1987-12-29 | 1989-11-21 | Smithkline Beckman Corporation | 2-(aminoalkylthio)imidazoles as dopamine-β-hydroxylase inhibitors |
| DE19620408A1 (de) * | 1996-05-21 | 1997-11-27 | Bayer Ag | Mercapto-imidazolyl-Derivate |
| US20080002735A1 (en) * | 1997-04-01 | 2008-01-03 | Paradox Security Systems Ltd. | Device network |
| US7965734B2 (en) * | 2005-12-15 | 2011-06-21 | Paradox Security Systems Ltd. | Device network interface |
| EP2822936B1 (en) | 2012-03-07 | 2021-09-08 | The McLean Hospital Corporation | Aminoquinoline derivatives and uses thereof |
| CN103214421B (zh) * | 2012-12-11 | 2016-03-02 | 上海博康精细化工有限公司 | 2-巯基-1-甲基咪唑的工业化生产方法 |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2180772A (en) * | 1935-10-25 | 1939-11-21 | Gen Aniline Works Inc | Trifluoromethyl benzaldehydes |
| DE1695093A1 (de) * | 1965-10-21 | 1970-12-10 | Geigy Ag J R | Neue Imidazolderivate |
| DE2259627A1 (de) * | 1972-12-06 | 1974-06-12 | Hoechst Ag | Imidazolyl-(2)-thio-alkansaeureester und verfahren zu ihrer herstellung |
| CA1108620A (en) * | 1976-12-20 | 1981-09-08 | Frederick C. Copp | Imidazolines |
| US4284641A (en) * | 1977-08-26 | 1981-08-18 | Burroughs Wellcome Co. | Pharmaceutically active imidazole derivatives |
| US4340738A (en) * | 1979-06-21 | 1982-07-20 | Janssen Pharmaceutica, N.V. | 2,3-Dihydro-imidazo[2,1-b]benzothiazoles |
| GB2096987B (en) * | 1981-04-22 | 1984-04-04 | Farmos Oy | Substituted imidazole and imidazole derivatives and their preparation and use |
| US4487761A (en) * | 1982-04-05 | 1984-12-11 | Merck & Co., Inc. | Dopamine β-hydroxylase inhibitors |
| US4532331A (en) * | 1983-04-12 | 1985-07-30 | Smithkline Beckman Corporation | 1-Benzyl-2-aminomethyl imidazole derivatives |
| PT78388B (en) * | 1983-04-12 | 1986-09-15 | Smithkline Beckman Corp | Dopamine-beta-hydroxylase inhibitors |
-
1985
- 1985-10-31 US US06/793,512 patent/US4719223A/en not_active Expired - Fee Related
-
1986
- 1986-10-27 ZW ZW215/86A patent/ZW21586A1/xx unknown
- 1986-10-27 PT PT83628A patent/PT83628B/pt unknown
- 1986-10-28 DK DK515786A patent/DK515786A/da not_active Application Discontinuation
- 1986-10-29 NZ NZ218098A patent/NZ218098A/xx unknown
- 1986-10-30 JP JP61259600A patent/JPS62108815A/ja active Pending
- 1986-10-30 EP EP86308482A patent/EP0221778A3/en not_active Withdrawn
- 1986-10-30 PH PH34429A patent/PH21776A/en unknown
- 1986-10-30 AU AU64639/86A patent/AU598485B2/en not_active Ceased
- 1986-10-30 FI FI864431A patent/FI864431A/fi not_active Application Discontinuation
- 1986-10-30 ZA ZA868269A patent/ZA868269B/xx unknown
- 1986-10-30 NO NO864337A patent/NO864337L/no unknown
- 1986-10-30 KR KR860009105A patent/KR870003994A/ko not_active Application Discontinuation
- 1986-10-31 HU HU864574A patent/HU197563B/hu not_active IP Right Cessation
- 1986-10-31 CN CN198686107151A patent/CN86107151A/zh active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| NO864337L (no) | 1987-05-04 |
| PT83628A (en) | 1986-11-01 |
| AU598485B2 (en) | 1990-06-28 |
| AU6463986A (en) | 1987-05-07 |
| FI864431A0 (fi) | 1986-10-30 |
| PT83628B (en) | 1988-11-15 |
| PH21776A (en) | 1988-02-24 |
| FI864431A (fi) | 1987-05-01 |
| EP0221778A2 (en) | 1987-05-13 |
| JPS62108815A (ja) | 1987-05-20 |
| NZ218098A (en) | 1989-07-27 |
| HUT43830A (en) | 1987-12-28 |
| EP0221778A3 (en) | 1988-03-23 |
| KR870003994A (ko) | 1987-05-06 |
| US4719223A (en) | 1988-01-12 |
| CN86107151A (zh) | 1987-05-13 |
| NO864337D0 (no) | 1986-10-30 |
| DK515786A (da) | 1987-05-01 |
| DK515786D0 (da) | 1986-10-28 |
| ZW21586A1 (en) | 1987-06-24 |
| HU197563B (en) | 1989-04-28 |
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