ZA865916B - 2-(heteroalkyl)-1,4-dihydropyridines,process for their preparations and pharmaceutical compositions containing them - Google Patents

2-(heteroalkyl)-1,4-dihydropyridines,process for their preparations and pharmaceutical compositions containing them

Info

Publication number
ZA865916B
ZA865916B ZA865916A ZA865916A ZA865916B ZA 865916 B ZA865916 B ZA 865916B ZA 865916 A ZA865916 A ZA 865916A ZA 865916 A ZA865916 A ZA 865916A ZA 865916 B ZA865916 B ZA 865916B
Authority
ZA
South Africa
Prior art keywords
sub
dihydropyridines
group
heteroalkyl
preparations
Prior art date
Application number
ZA865916A
Other languages
English (en)
Inventor
Carmelo A Gandolfi
Marco Frigerio
Silvano Spinelli
Odoardo Tofanetti
Sergio Tognella
Original Assignee
Boehringer Biochemia Srl
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Biochemia Srl filed Critical Boehringer Biochemia Srl
Publication of ZA865916B publication Critical patent/ZA865916B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/80—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D211/84—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
    • C07D211/90—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/06—Antianaemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
ZA865916A 1985-08-06 1986-09-06 2-(heteroalkyl)-1,4-dihydropyridines,process for their preparations and pharmaceutical compositions containing them ZA865916B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT8521875A IT1215298B (it) 1985-08-06 1985-08-06 2-(eteroalchil)-1,4-diidropiridine ed un processo per la loro produzione.

Publications (1)

Publication Number Publication Date
ZA865916B true ZA865916B (en) 1987-04-29

Family

ID=11188086

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA865916A ZA865916B (en) 1985-08-06 1986-09-06 2-(heteroalkyl)-1,4-dihydropyridines,process for their preparations and pharmaceutical compositions containing them

Country Status (8)

Country Link
US (1) US4839348A (fr)
EP (1) EP0212340B1 (fr)
JP (1) JPS6277367A (fr)
AT (1) ATE96434T1 (fr)
CA (1) CA1270251A (fr)
DE (1) DE3689213D1 (fr)
IT (1) IT1215298B (fr)
ZA (1) ZA865916B (fr)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0717645B2 (ja) * 1985-09-06 1995-03-01 株式会社三和化学研究所 新規な１，４―ジヒドロピリジン誘導体及びその塩並びにこれらの化合物を有効成分とする循環器系作用剤
FR2602231B1 (fr) * 1986-08-04 1988-10-28 Adir Nouveaux derives de la dihydro-1,4 pyridine, leurs procedes de preparation et les compositions pharmaceutiques qui les contiennent
ATE548351T1 (de) * 1996-01-29 2012-03-15 Us Of America Represented By The Secretary Dept Of Health And Human Services Dihydropyridin-pyridin-, benzopyranon- und triazolochinazolin-derivate, deren herstellung und verwendung als adenosinrezeptor-antagonisten
AU2603197A (en) 1996-04-10 1997-10-29 United States Of America, Represented By The Secretary, Department Of Health And Human Services, The Use of an a1 adenosine receptor agonist to treat cerebral ischaemia
CA2287663C (fr) 1998-11-02 2008-04-08 Isao Kurimoto Procede de production de l'ester d'acide 2-alkylidene-4-bromoacetoacetique
EP1312247A2 (fr) * 2000-07-05 2003-05-21 CRT Holdings, Inc. Reacteur a plasma a demarrage par rayonnement electromagnetique

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1552911A (en) * 1975-07-02 1979-09-19 Fujisawa Pharmaceutical Co 1,4 dihydropyridine derivatives and the preparation thereof
US4284634A (en) * 1975-07-02 1981-08-18 Fujisawa Pharmaceutical Co., Ltd. 1,4-Dihydropyridine derivatives, and pharmaceutical method of the same
DE2658183A1 (de) * 1976-12-22 1978-07-06 Bayer Ag In 2-position substituierte 1,4- dihydropyridin-derivate, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel
US4177278A (en) * 1977-04-05 1979-12-04 Bayer Aktiengesellschaft 2-Alkyleneaminodihydropyridines compounds, their production and their medicinal use
NZ201395A (en) * 1981-07-30 1987-02-20 Bayer Ag Pharmaceutical compositions containing 1,4-dihydropyridines and certain of these dihydropyridines
US4497808A (en) * 1981-12-30 1985-02-05 Ciba-Geigy Corporation N-Oxide compounds useful in the treatment of cardiovascular ailments
JPS59161392A (ja) * 1983-03-04 1984-09-12 Nippon Shinyaku Co Ltd ジヒドロピリジン誘導体及びその製法
GB8311519D0 (en) * 1983-04-27 1983-06-02 Fisons Plc Nitrogen heterocycles
EP0141221A1 (fr) * 1983-09-26 1985-05-15 Nissan Chemical Industries Ltd. Ester d'acide dihydro-1,4-pyridinephosphonique-5
EP0169009A3 (fr) * 1984-07-17 1988-08-31 FISONS plc Dérivés de dihydropyridine et leur préparation, leur formulation et leur utilisation comme produits pharmaceutiques
GB8422139D0 (en) * 1984-09-01 1984-10-03 Fisons Plc Biologically active nitrogen heterocyclics

Also Published As

Publication number Publication date
DE3689213D1 (de) 1993-12-02
ATE96434T1 (de) 1993-11-15
IT8521875A0 (it) 1985-08-06
EP0212340B1 (fr) 1993-10-27
EP0212340A1 (fr) 1987-03-04
US4839348A (en) 1989-06-13
IT1215298B (it) 1990-01-31
CA1270251A (fr) 1990-06-12
JPS6277367A (ja) 1987-04-09

Similar Documents

Publication Publication Date Title
HU895815D0 (en) Insecticide compositions containing heterocyclic compounds and process for the preparation of such compounds
MA21502A1 (fr) 4--phenyl-(-piperazinyl)phenols et procedes pour leur preparation .
ES8203888A1 (es) Procedimiento para la obtencion de dihidropiridinas susti- tuidas en la posicion 4 del hetero-anillo
ES8301927A1 (es) Procedimiento de preparacion de acidos azabiciclohexano car-boxilicos y de sus sales
MY117680A (en) 1-(1,2-disubstituted piperidinyl)-4-(fused imidazole)- piperidine derivatives
TW368501B (en) 7-(2-aminoethyl)-benzothiazolones
DE3478746D1 (en) Dihydropyridine anti-ischaemic and antihypertensive agents
JO1617B1 (en) Modern 2-amino-tetraline-8 compounds
MY109430A (en) Aryl-fused and hetaryl-fused-2, 4-diazepine and 2, 4-diazocine antiarrhythmic agents.
PH24176A (en) New bicyclic compounds,process for preparation thereof and pharmaceutical composition comprising the same
ZA865916B (en) 2-(heteroalkyl)-1,4-dihydropyridines,process for their preparations and pharmaceutical compositions containing them
AU649099B2 (en) Use of 4-(3-trifluoromethylphenyl)-1,2,3,6-tetrahydropyridine derivatives as free radical scavengers
ES8307792A1 (es) Un metodo de produccion de compuesto de dihidropiridina.
ES8801545A1 (es) Un procedimiento para la preparacion de compuestos aminoheterociclicos
PT83845B (en) Process for preparing antihypertensive pharmaceutical combination products containing a dihydropyridine and a pyridazodiazepine
ES2016017A6 (es) Procedimiento para preparar derivados de acido 1,1-dioxocefem-4-carbotiolico.
ES2003100A6 (es) Un procedimiento para preparar imidazoles
ES8707939A1 (es) Procedimiento para preparar derivados de n-carboxialquil-2--oxo-3-diaril-5,6-triazinas
ES8405020A1 (es) Un procedimiento para la preparacion de derivados de fosfolipidos.
GR3000488T3 (en) Novel 1,4-dihydropyridines containing fluorine, process for their preparation and their use as medicaments
MY104164A (en) Heterocyclic compounds.
JPS6463569A (en) Heteroaryl derivative
NZ222973A (en) Substituted piperidine and azepine derivatives and pharmaceutical compositions