ZA865272B - High level production of bovine growth hormones - Google Patents
High level production of bovine growth hormonesInfo
- Publication number
- ZA865272B ZA865272B ZA865272A ZA865272A ZA865272B ZA 865272 B ZA865272 B ZA 865272B ZA 865272 A ZA865272 A ZA 865272A ZA 865272 A ZA865272 A ZA 865272A ZA 865272 B ZA865272 B ZA 865272B
- Authority
- ZA
- South Africa
- Prior art keywords
- protein
- temperature
- medium
- bovine growth
- transformant
- Prior art date
Links
- 238000004519 manufacturing process Methods 0.000 title abstract 3
- 241000283690 Bos taurus Species 0.000 title 1
- 239000000122 growth hormone Substances 0.000 title 1
- 108090000623 proteins and genes Proteins 0.000 abstract 6
- 102000004169 proteins and genes Human genes 0.000 abstract 4
- 108010006025 bovine growth hormone Proteins 0.000 abstract 3
- 230000003054 hormonal effect Effects 0.000 abstract 3
- 241000588724 Escherichia coli Species 0.000 abstract 2
- 102000009661 Repressor Proteins Human genes 0.000 abstract 2
- 108010034634 Repressor Proteins Proteins 0.000 abstract 2
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 abstract 2
- 238000000855 fermentation Methods 0.000 abstract 2
- 230000004151 fermentation Effects 0.000 abstract 2
- 229910052760 oxygen Inorganic materials 0.000 abstract 2
- 239000001301 oxygen Substances 0.000 abstract 2
- 241000701959 Escherichia virus Lambda Species 0.000 abstract 1
- 230000010261 cell growth Effects 0.000 abstract 1
- 230000012010 growth Effects 0.000 abstract 1
- 230000006698 induction Effects 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/70—Vectors or expression systems specially adapted for E. coli
- C12N15/73—Expression systems using phage (lambda) regulatory sequences
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/61—Growth hormone [GH], i.e. somatotropin
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/818—Aeration or oxygen transfer technique
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Genetics & Genomics (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Endocrinology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- Biophysics (AREA)
- Biomedical Technology (AREA)
- General Health & Medical Sciences (AREA)
- Microbiology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Virology (AREA)
- Plant Pathology (AREA)
- Toxicology (AREA)
- Gastroenterology & Hepatology (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Fodder In General (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Feed For Specific Animals (AREA)
- Crystals, And After-Treatments Of Crystals (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US06/754,578 US4762784A (en) | 1985-07-15 | 1985-07-15 | Fermemtation process for the high level production of bovine growth hormone |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA865272B true ZA865272B (en) | 1987-03-25 |
Family
ID=25035421
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA865272A ZA865272B (en) | 1985-07-15 | 1986-07-15 | High level production of bovine growth hormones |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US4762784A (ja) |
| EP (1) | EP0209355B1 (ja) |
| JP (1) | JPH0716433B2 (ja) |
| AT (1) | ATE70303T1 (ja) |
| AU (1) | AU601157B2 (ja) |
| CA (1) | CA1279591C (ja) |
| DE (1) | DE3682840D1 (ja) |
| DK (1) | DK336886A (ja) |
| IE (1) | IE61272B1 (ja) |
| IL (1) | IL79404A0 (ja) |
| NZ (1) | NZ216834A (ja) |
| ZA (1) | ZA865272B (ja) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4788144A (en) * | 1985-06-28 | 1988-11-29 | International Minerals & Chemical Corp. | Fermentation process for the high level production of swine growth |
| US5104796A (en) * | 1987-04-06 | 1992-04-14 | International Minerals & Chemical Corp. | High titer production of human somatomedin c |
| AU3058489A (en) * | 1988-02-17 | 1989-09-06 | Upjohn Company, The | Methods for controlling norleucine content in polypeptides |
| US5622845A (en) * | 1988-02-17 | 1997-04-22 | The Upjohn Company | Fermentation method for producing norleucine |
| US5342763A (en) * | 1992-11-23 | 1994-08-30 | Genentech, Inc. | Method for producing polypeptide via bacterial fermentation |
| CN101591690B (zh) * | 2008-05-29 | 2012-02-01 | 北京凯因科技股份有限公司 | 一种重组人干扰素α2b的高密度发酵方法 |
| US9534026B2 (en) | 2013-10-31 | 2017-01-03 | China National Research Institute Of Food & Fermentation Industries | Corn active peptide additive for cell culture medium |
| CN104593318B (zh) * | 2013-10-31 | 2018-05-04 | 中国食品发酵工业研究院 | 一种用于细胞培养基的玉米活性肽添加剂 |
| US10920251B2 (en) | 2016-05-05 | 2021-02-16 | William Marsh Rice University | Microbial production of fats |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4167450A (en) * | 1977-07-13 | 1979-09-11 | University Of New Hampshire | Method and apparatus for the production of secondary metabolites by the maintenance-state cultivation of microorganisms |
| DE3015699C2 (de) * | 1979-04-26 | 1982-07-15 | Asahi Kasei Kogyo K.K., Osaka | Herstellung eines Plasminogen-Aktivators |
| EP0103395A3 (en) * | 1982-08-17 | 1985-05-22 | Biogen N.V. | Dna sequences, recombinant dna molecules and processes for producing bovine growth hormone-like polypeptides in high yield |
| EP0111814A3 (en) * | 1982-12-16 | 1985-08-14 | Mgi Pharma, Inc. | The cloning and expression of nucleotide sequences encoding bovine growth hormone |
| BG49718A3 (en) * | 1983-07-15 | 1992-01-15 | Bio- Technology General Corp | Method for preparing of polypeptid with superoxiddismutasne activitty |
| US4569790A (en) * | 1984-03-28 | 1986-02-11 | Cetus Corporation | Process for recovering microbially produced interleukin-2 and purified recombinant interleukin-2 compositions |
-
1985
- 1985-07-15 US US06/754,578 patent/US4762784A/en not_active Expired - Fee Related
-
1986
- 1986-07-14 AU AU60200/86A patent/AU601157B2/en not_active Ceased
- 1986-07-14 NZ NZ216834A patent/NZ216834A/xx unknown
- 1986-07-14 CA CA000513717A patent/CA1279591C/en not_active Expired - Lifetime
- 1986-07-14 IL IL79404A patent/IL79404A0/xx not_active IP Right Cessation
- 1986-07-14 IE IE187786A patent/IE61272B1/en not_active IP Right Cessation
- 1986-07-15 DK DK336886A patent/DK336886A/da not_active Application Discontinuation
- 1986-07-15 EP EP86305430A patent/EP0209355B1/en not_active Expired - Lifetime
- 1986-07-15 ZA ZA865272A patent/ZA865272B/xx unknown
- 1986-07-15 DE DE8686305430T patent/DE3682840D1/de not_active Expired - Fee Related
- 1986-07-15 JP JP61164846A patent/JPH0716433B2/ja not_active Expired - Lifetime
- 1986-07-15 AT AT86305430T patent/ATE70303T1/de not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| IE861877L (en) | 1987-01-15 |
| AU601157B2 (en) | 1990-09-06 |
| EP0209355B1 (en) | 1991-12-11 |
| JPS6265698A (ja) | 1987-03-24 |
| JPH0716433B2 (ja) | 1995-03-01 |
| CA1279591C (en) | 1991-01-29 |
| DE3682840D1 (de) | 1992-01-23 |
| NZ216834A (en) | 1988-08-30 |
| US4762784A (en) | 1988-08-09 |
| EP0209355A1 (en) | 1987-01-21 |
| IE61272B1 (en) | 1994-10-19 |
| AU6020086A (en) | 1987-01-22 |
| DK336886A (da) | 1987-01-16 |
| IL79404A0 (en) | 1986-10-31 |
| ATE70303T1 (de) | 1991-12-15 |
| DK336886D0 (da) | 1986-07-15 |
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