JPS6485094A - Novel physiologically active polypeptide - Google Patents

Novel physiologically active polypeptide

Info

Publication number
JPS6485094A
JPS6485094A JP62237552A JP23755287A JPS6485094A JP S6485094 A JPS6485094 A JP S6485094A JP 62237552 A JP62237552 A JP 62237552A JP 23755287 A JP23755287 A JP 23755287A JP S6485094 A JPS6485094 A JP S6485094A
Authority
JP
Japan
Prior art keywords
physiologically active
active polypeptide
novel physiologically
novel
cells
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP62237552A
Other languages
Japanese (ja)
Inventor
Satoshi Nakamura
Tsukio Sakugi
Kazuo Kitai
Yataro Ichikawa
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Teijin Ltd
Original Assignee
Teijin Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Teijin Ltd filed Critical Teijin Ltd
Priority to JP62237552A priority Critical patent/JPS6485094A/en
Publication of JPS6485094A publication Critical patent/JPS6485094A/en
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/525—Tumour necrosis factor [TNF]

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)

Abstract

PURPOSE:To produce novel physiologically active protein having antitumor activity, by culturing the cells of a microorganism which is transformed with a recombinant plasmid containing DNA coding the novel physiologically active polypeptide. CONSTITUTION:A recombinant plasmid containing the DNA coding a novel physiologically active polypeptide, e.g., pTNF498A, pTNF498B is introduced into a host of a microorganism such as Escherichia coli C600r-m line (ATCC33525) in a known manner. Then, the recombinant cells are cultured in a usual manner to collect a novel antitumor active polypeptide from the cultured cells.
JP62237552A 1987-09-24 1987-09-24 Novel physiologically active polypeptide Pending JPS6485094A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP62237552A JPS6485094A (en) 1987-09-24 1987-09-24 Novel physiologically active polypeptide

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP62237552A JPS6485094A (en) 1987-09-24 1987-09-24 Novel physiologically active polypeptide

Publications (1)

Publication Number Publication Date
JPS6485094A true JPS6485094A (en) 1989-03-30

Family

ID=17017022

Family Applications (1)

Application Number Title Priority Date Filing Date
JP62237552A Pending JPS6485094A (en) 1987-09-24 1987-09-24 Novel physiologically active polypeptide

Country Status (1)

Country Link
JP (1) JPS6485094A (en)

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