ZA864042B - 13-halomilbemycin derivatives,their preparation and composition containing them - Google Patents

13-halomilbemycin derivatives,their preparation and composition containing them

Info

Publication number
ZA864042B
ZA864042B ZA864042A ZA864042A ZA864042B ZA 864042 B ZA864042 B ZA 864042B ZA 864042 A ZA864042 A ZA 864042A ZA 864042 A ZA864042 A ZA 864042A ZA 864042 B ZA864042 B ZA 864042B
Authority
ZA
South Africa
Prior art keywords
derivatives
halomilbemycin
preparation
composition containing
oxime group
Prior art date
Application number
ZA864042A
Other languages
English (en)
Inventor
Kazuo Sato
Toshiaki Yanai
Noritoshi Kitano
Akira Nishida
Bruno Frei
Anthony Sullivan
Original Assignee
Sankyo Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sankyo Co filed Critical Sankyo Co
Publication of ZA864042B publication Critical patent/ZA864042B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/01—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing oxygen
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/90—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having two or more relevant hetero rings, condensed among themselves or with a common carbocyclic ring system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/10—Anthelmintics

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Veterinary Medicine (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Environmental Sciences (AREA)
  • Plant Pathology (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Pest Control & Pesticides (AREA)
  • Molecular Biology (AREA)
  • Agronomy & Crop Science (AREA)
  • Dentistry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
ZA864042A 1985-05-31 1986-05-30 13-halomilbemycin derivatives,their preparation and composition containing them ZA864042B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP11862985 1985-05-31

Publications (1)

Publication Number Publication Date
ZA864042B true ZA864042B (en) 1987-01-28

Family

ID=14741259

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA864042A ZA864042B (en) 1985-05-31 1986-05-30 13-halomilbemycin derivatives,their preparation and composition containing them

Country Status (12)

Country Link
US (1) US4945105A (esLanguage)
EP (1) EP0203832B1 (esLanguage)
JP (1) JPS6289685A (esLanguage)
CN (1) CN1018456B (esLanguage)
AT (1) ATE52781T1 (esLanguage)
BR (1) BR8602522A (esLanguage)
DE (1) DE3671228D1 (esLanguage)
EG (1) EG18548A (esLanguage)
ES (1) ES8707242A1 (esLanguage)
OA (1) OA08336A (esLanguage)
SU (1) SU1537140A3 (esLanguage)
ZA (1) ZA864042B (esLanguage)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU609032B2 (en) * 1986-03-12 1991-04-26 American Cyanamid Company Macrolide compounds
DK168866B1 (da) * 1986-03-12 1994-06-27 American Cyanamid Co 5-Keto-S541-macrolidforbindelse; krystallinsk produkt indeholdende over 90 % af forbindelsen; præparater indeholdende forbindelsen til anvendelse inden for human- og veterinærmedicin; skadedyrsbekæmpelsespræparat indeholdende forbindelsen; ikke-terapeutisk fremgangsmåde til bekæmpelse af skadedyr under anvendelse af forbindelsen; fremgangsmåde til fremstilling af et fermentationsmedium indeholdend
EP0342710B1 (en) * 1986-03-25 1993-05-19 Sankyo Company Limited Macrolide compounds, their preparation and their use
US4897416A (en) * 1987-02-18 1990-01-30 Ciba-Geigy Corporation Insecticides and parasiticides
US4806527A (en) * 1987-03-16 1989-02-21 Merck & Co., Inc. Avermectin derivatives
US4918097A (en) * 1988-03-11 1990-04-17 Ciba-Geigy Corporation Insecticides and parasiticides
NZ228866A (en) * 1988-05-02 1991-10-25 Merck & Co Inc Fluoro-substituted milbemycins and avermectins for combatting parasites and insects
US5428034A (en) * 1988-09-02 1995-06-27 Sankyo Co., Ltd. Milbemycin derivatives, their preparation and their use
US5030650A (en) * 1989-09-11 1991-07-09 American Cyanamid Company 13-halo-23-imino derivatives of LL-F28249 compounds and their use as endo- and ectoparasiticidal, insecticidal, acaricidal and nematocidal agents
DE69100177T2 (de) * 1990-02-08 1994-01-27 Merck & Co Inc Verfahren zur Bekämpfung von Flöhen.
JP2622197B2 (ja) * 1990-03-01 1997-06-18 三共株式会社 １３−エーテル置換ミルベマイシン誘導体
KR0171426B1 (ko) * 1991-12-18 1999-02-01 가와무라 요시부미 13-(치환 티오) 아세톡시밀베마이신 유도체, 그의 제조방법 및 농화학적 용도
US5229416A (en) * 1992-04-29 1993-07-20 Merck & Co., Inc. Avermectin difluoro derivatives
US5411946A (en) * 1993-02-24 1995-05-02 Merck & Co., Inc. Avermectin derivatives
US5614470A (en) * 1994-04-01 1997-03-25 Sankyo Company, Limited 13-substituted milbemycin derivatives, their preparation and their use
AU707152B2 (en) * 1995-09-29 1999-07-01 Novartis Animal Health K.K. 13-substituted milbemycin 5-oxime derivatives, their preparation and their use against insects and other pests
NZ522247A (en) 2000-04-27 2004-07-30 Sankyo Lifetech Company Ltd 13-substituted milbemycin derivatives, their preparation and their use against insects and other pests
EP1849363A1 (en) * 2006-03-09 2007-10-31 Cheminova A/S Synergistic combination of glutamate- and GABA-gated chloride agonist pesticide and at least one of Vitamin E or Niacin
EP2886640A1 (en) 2013-12-18 2015-06-24 Riga Technical University Process for isolation of milbemycins A3 and A4
CN104327094B (zh) * 2014-10-30 2016-08-17 湖北宏中药业有限公司 一种米尔贝肟的分离纯化方法
CN105254644B (zh) * 2015-11-04 2017-07-18 湖北宏中药业股份有限公司 一种米尔贝肟的制备方法
CN108640927B (zh) * 2018-04-27 2021-05-07 丽珠集团福州福兴医药有限公司 一种米尔贝肟的制备方法

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US32034A (en) * 1861-04-09 Langdon sawyer
US3950360A (en) 1972-06-08 1976-04-13 Sankyo Company Limited Antibiotic substances
US4093629A (en) 1977-04-11 1978-06-06 Merck & Co., Inc. Derivatives of antibiotic substance milbemycin and processes therefor
US4134973A (en) * 1977-04-11 1979-01-16 Merck & Co., Inc. Carbohydrate derivatives of milbemycin and processes therefor
US4173571A (en) 1977-12-19 1979-11-06 Merck & Co., Inc. 13-Halo and 13-deoxy derivatives of C-076 compounds
USRE32034E (en) 1977-12-19 1985-11-19 Merck & Co., Inc. 13-Halo and 13-deoxy derivatives of C-076 compounds
PH16612A (en) * 1977-12-19 1983-11-28 Merck & Co Inc 13-halo and 13-deoxy derivatives of c-076 compounds
JPS5632481A (en) * 1979-08-23 1981-04-01 Sankyo Co Ltd Antibiotic b-41d, its preparation, and acaricide and anthelminthic agent and repellent containing the same as active constituent
US4423209A (en) 1982-02-26 1983-12-27 Merck & Co., Inc. Processes for the interconversion of avermectin compounds
JPS59108785A (ja) 1982-11-25 1984-06-23 Sankyo Co Ltd ミルベマイシン類の５−オキシム誘導体

Also Published As

Publication number Publication date
JPS6289685A (ja) 1987-04-24
OA08336A (fr) 1988-02-29
CN1018456B (zh) 1992-09-30
JPH0586794B2 (esLanguage) 1993-12-14
EP0203832A1 (en) 1986-12-03
CN86104380A (zh) 1987-02-11
US4945105A (en) 1990-07-31
ES8707242A1 (es) 1987-07-16
SU1537140A3 (ru) 1990-01-15
BR8602522A (pt) 1987-01-27
DE3671228D1 (de) 1990-06-21
EP0203832B1 (en) 1990-05-16
EG18548A (en) 1993-06-30
ES555569A0 (es) 1987-07-16
ATE52781T1 (de) 1990-06-15

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