ATE52781T1 - 13-halogenierte milbemycinderivate, ihre herstellung und die sie enthaltenden zusammensetzungen. - Google Patents

13-halogenierte milbemycinderivate, ihre herstellung und die sie enthaltenden zusammensetzungen.

Info

Publication number
ATE52781T1
ATE52781T1 AT86304186T AT86304186T ATE52781T1 AT E52781 T1 ATE52781 T1 AT E52781T1 AT 86304186 T AT86304186 T AT 86304186T AT 86304186 T AT86304186 T AT 86304186T AT E52781 T1 ATE52781 T1 AT E52781T1
Authority
AT
Austria
Prior art keywords
halogenated
production
compositions containing
milbemycin derivatives
derivatives
Prior art date
Application number
AT86304186T
Other languages
English (en)
Inventor
Kazuo Sato
Toshiaki Yanai
Noritoshi Kitano
Akira Nishida
Bruno Frei
Anthony O'sullivan
Original Assignee
Sankyo Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sankyo Co filed Critical Sankyo Co
Application granted granted Critical
Publication of ATE52781T1 publication Critical patent/ATE52781T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/01—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing oxygen
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/90—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having two or more relevant hetero rings, condensed among themselves or with a common carbocyclic ring system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/10—Anthelmintics

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Veterinary Medicine (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Agronomy & Crop Science (AREA)
  • Pest Control & Pesticides (AREA)
  • Plant Pathology (AREA)
  • Dentistry (AREA)
  • Biochemistry (AREA)
  • Zoology (AREA)
  • Environmental Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
AT86304186T 1985-05-31 1986-06-02 13-halogenierte milbemycinderivate, ihre herstellung und die sie enthaltenden zusammensetzungen. ATE52781T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP11862985 1985-05-31
EP86304186A EP0203832B1 (de) 1985-05-31 1986-06-02 13-Halogenierte Milbemycinderivate, ihre Herstellung und die sie enthaltenden Zusammensetzungen

Publications (1)

Publication Number Publication Date
ATE52781T1 true ATE52781T1 (de) 1990-06-15

Family

ID=14741259

Family Applications (1)

Application Number Title Priority Date Filing Date
AT86304186T ATE52781T1 (de) 1985-05-31 1986-06-02 13-halogenierte milbemycinderivate, ihre herstellung und die sie enthaltenden zusammensetzungen.

Country Status (12)

Country Link
US (1) US4945105A (de)
EP (1) EP0203832B1 (de)
JP (1) JPS6289685A (de)
CN (1) CN1018456B (de)
AT (1) ATE52781T1 (de)
BR (1) BR8602522A (de)
DE (1) DE3671228D1 (de)
EG (1) EG18548A (de)
ES (1) ES8707242A1 (de)
OA (1) OA08336A (de)
SU (1) SU1537140A3 (de)
ZA (1) ZA864042B (de)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH671764A5 (de) * 1986-03-12 1989-09-29 Glaxo Group Ltd
JP2577734B2 (ja) * 1986-03-12 1997-02-05 アメリカン・サイアナミツド・カンパニー マクロライド抗生物質
AR243191A1 (es) * 1986-03-25 1993-07-30 Sankyo Co Procedimiento para preparar compuestos de macrolida
US4897416A (en) * 1987-02-18 1990-01-30 Ciba-Geigy Corporation Insecticides and parasiticides
US4806527A (en) * 1987-03-16 1989-02-21 Merck & Co., Inc. Avermectin derivatives
US4918097A (en) * 1988-03-11 1990-04-17 Ciba-Geigy Corporation Insecticides and parasiticides
NZ228866A (en) * 1988-05-02 1991-10-25 Merck & Co Inc Fluoro-substituted milbemycins and avermectins for combatting parasites and insects
US5428034A (en) * 1988-09-02 1995-06-27 Sankyo Co., Ltd. Milbemycin derivatives, their preparation and their use
US5030650A (en) * 1989-09-11 1991-07-09 American Cyanamid Company 13-halo-23-imino derivatives of LL-F28249 compounds and their use as endo- and ectoparasiticidal, insecticidal, acaricidal and nematocidal agents
EP0443733B1 (de) * 1990-02-08 1993-07-21 Merck & Co. Inc. Verfahren zur Bekämpfung von Flöhen
JP2622197B2 (ja) * 1990-03-01 1997-06-18 三共株式会社 １３−エーテル置換ミルベマイシン誘導体
KR0171426B1 (ko) * 1991-12-18 1999-02-01 가와무라 요시부미 13-(치환 티오) 아세톡시밀베마이신 유도체, 그의 제조방법 및 농화학적 용도
US5229416A (en) * 1992-04-29 1993-07-20 Merck & Co., Inc. Avermectin difluoro derivatives
US5411946A (en) * 1993-02-24 1995-05-02 Merck & Co., Inc. Avermectin derivatives
US5614470A (en) * 1994-04-01 1997-03-25 Sankyo Company, Limited 13-substituted milbemycin derivatives, their preparation and their use
CA2186650A1 (en) * 1995-09-29 1997-03-30 Kazuo Sato 13-substituted milbemycin 5-oxime derivatives, their preparation and their use against insects and others pests
AU5261301A (en) 2000-04-27 2001-11-12 Sankyo Co 13-substituted milbemycin derivatives, their preparation and their use against insects and other pests
EP1849363A1 (de) * 2006-03-09 2007-10-31 Cheminova A/S Synergistische Kombinationen aus Glutaminsäure- und GABA-aktivierten Chloridkanälen agonistischen Pestiziden und mindestens eins von Vitamin E und Niacin
EP2886640A1 (de) 2013-12-18 2015-06-24 Riga Technical University Trennverfahren für Milbemycin A3 und A4
CN104327094B (zh) * 2014-10-30 2016-08-17 湖北宏中药业有限公司 一种米尔贝肟的分离纯化方法
CN105254644B (zh) * 2015-11-04 2017-07-18 湖北宏中药业股份有限公司 一种米尔贝肟的制备方法
CN108640927B (zh) * 2018-04-27 2021-05-07 丽珠集团福州福兴医药有限公司 一种米尔贝肟的制备方法

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US32034A (en) * 1861-04-09 Langdon sawyer
US3950360A (en) 1972-06-08 1976-04-13 Sankyo Company Limited Antibiotic substances
US4134973A (en) * 1977-04-11 1979-01-16 Merck & Co., Inc. Carbohydrate derivatives of milbemycin and processes therefor
US4093629A (en) 1977-04-11 1978-06-06 Merck & Co., Inc. Derivatives of antibiotic substance milbemycin and processes therefor
US4173571A (en) 1977-12-19 1979-11-06 Merck & Co., Inc. 13-Halo and 13-deoxy derivatives of C-076 compounds
IL56149A (en) * 1977-12-19 1989-09-28 Merck & Co Inc 13-halo and 13-deoxy derivatives of c-076 compounds,their preparation and method for the treatment of parasitic infections in animals therewith
JPS5632481A (en) * 1979-08-23 1981-04-01 Sankyo Co Ltd Antibiotic b-41d, its preparation, and acaricide and anthelminthic agent and repellent containing the same as active constituent
US4423209A (en) 1982-02-26 1983-12-27 Merck & Co., Inc. Processes for the interconversion of avermectin compounds
JPS59108785A (ja) 1982-11-25 1984-06-23 Sankyo Co Ltd ミルベマイシン類の５−オキシム誘導体

Also Published As

Publication number Publication date
US4945105A (en) 1990-07-31
CN86104380A (zh) 1987-02-11
EP0203832A1 (de) 1986-12-03
DE3671228D1 (de) 1990-06-21
ZA864042B (en) 1987-01-28
OA08336A (fr) 1988-02-29
EG18548A (en) 1993-06-30
CN1018456B (zh) 1992-09-30
ES8707242A1 (es) 1987-07-16
BR8602522A (pt) 1987-01-27
ES555569A0 (es) 1987-07-16
EP0203832B1 (de) 1990-05-16
JPS6289685A (ja) 1987-04-24
JPH0586794B2 (de) 1993-12-14
SU1537140A3 (ru) 1990-01-15

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