ATE16190T1 - Derivate von c-076 verbindungen, deren herstellung und benuetzung, und sie enthaltende zusammensetzungen. - Google Patents

Derivate von c-076 verbindungen, deren herstellung und benuetzung, und sie enthaltende zusammensetzungen.

Info

Publication number
ATE16190T1
ATE16190T1 AT82304518T AT82304518T ATE16190T1 AT E16190 T1 ATE16190 T1 AT E16190T1 AT 82304518 T AT82304518 T AT 82304518T AT 82304518 T AT82304518 T AT 82304518T AT E16190 T1 ATE16190 T1 AT E16190T1
Authority
AT
Austria
Prior art keywords
compounds
derivatives
production
compositions containing
compositions
Prior art date
Application number
AT82304518T
Other languages
English (en)
Inventor
Robert E Ormond
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Application granted granted Critical
Publication of ATE16190T1 publication Critical patent/ATE16190T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/01—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing oxygen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C12N1/205—Bacterial isolates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/44—Preparation of O-glycosides, e.g. glucosides
    • C12P19/60—Preparation of O-glycosides, e.g. glucosides having an oxygen of the saccharide radical directly bound to a non-saccharide heterocyclic ring or a condensed ring system containing a non-saccharide heterocyclic ring, e.g. coumermycin, novobiocin
    • C12P19/62—Preparation of O-glycosides, e.g. glucosides having an oxygen of the saccharide radical directly bound to a non-saccharide heterocyclic ring or a condensed ring system containing a non-saccharide heterocyclic ring, e.g. coumermycin, novobiocin the hetero ring having eight or more ring members and only oxygen as ring hetero atoms, e.g. erythromycin, spiramycin, nystatin
    • C12P19/623—Avermectin; Milbemycin; Ivermectin; C-076
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/465—Streptomyces

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Molecular Biology (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Virology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Saccharide Compounds (AREA)
  • Fodder In General (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
AT82304518T 1981-08-28 1982-08-26 Derivate von c-076 verbindungen, deren herstellung und benuetzung, und sie enthaltende zusammensetzungen. ATE16190T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US06/297,442 US4412991A (en) 1981-08-28 1981-08-28 22-Hydroxy derivatives of C-076 compounds, pharmaceutical compositions and method of use
EP82304518A EP0073660B1 (de) 1981-08-28 1982-08-26 Derivate von C-076 Verbindungen, deren Herstellung und Benützung, und sie enthaltende Zusammensetzungen

Publications (1)

Publication Number Publication Date
ATE16190T1 true ATE16190T1 (de) 1985-11-15

Family

ID=23146330

Family Applications (1)

Application Number Title Priority Date Filing Date
AT82304518T ATE16190T1 (de) 1981-08-28 1982-08-26 Derivate von c-076 verbindungen, deren herstellung und benuetzung, und sie enthaltende zusammensetzungen.

Country Status (13)

Country Link
US (1) US4412991A (de)
EP (1) EP0073660B1 (de)
JP (1) JPS5852300A (de)
AT (1) ATE16190T1 (de)
AU (1) AU554105B2 (de)
CA (1) CA1183476A (de)
DE (1) DE3267043D1 (de)
DK (1) DK384282A (de)
ES (1) ES8400144A1 (de)
GR (1) GR77605B (de)
NZ (1) NZ201594A (de)
PT (1) PT75437A (de)
ZA (1) ZA826283B (de)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0170006B1 (de) * 1984-06-05 1992-07-08 American Cyanamid Company Wirkstoffe und deren Herstellungsverfahren, Verfahren und Zusamensetzungen, die diese Wirkstoffe enthalten zur Bekämpfung von helmintischen, arthropodischen, ectoparasitischen und acaridischen Infektionen
US5169956A (en) * 1984-06-05 1992-12-08 American Cyanamid Company Macrolide antibiotic compounds
US5198464A (en) * 1984-06-05 1993-03-30 American Cyanamid Company Method and compositions for helmintic, arthropod ectoparasitic and acaridal infections with novel agents
US5317030A (en) * 1984-06-05 1994-05-31 American Cyanamid Company Method and compositions for helmintic, arthropod ectoparasitic and acaridal infections with novel agents
GB2168345B (en) * 1984-12-14 1988-05-25 Ciba Geigy Ag Pesticidal 13b-substituted milbemycin derivatives
US4581345A (en) * 1985-04-08 1986-04-08 Merck & Co., Inc. Avermectin 8,9-cyclopropyl compounds, pharmaceutical composition and therapeutic methods of use
NZ216908A (en) * 1985-07-29 1989-06-28 Merck & Co Inc Avermectin derivatives
ES8605582A1 (es) * 1985-12-11 1986-03-16 Antibioticos Sa Un procedimiento para la preparacion de avermectinas
US5212322A (en) * 1986-12-11 1993-05-18 Sankyo Company, Limited Macrolide compounds, their preparation and their use
AR243528A1 (es) * 1986-12-11 1993-08-31 Sankyo Co Procedimiento para preparar compuestos de macrolida y un procedimiento para producir con los mismos una composicion parasiticida.
GB8709327D0 (en) * 1987-04-21 1987-05-28 Beecham Group Plc Compounds
EP0319142B1 (de) * 1987-11-03 1994-04-06 Beecham Group Plc Zwischenprodukte für die Herstellung makrolider Antibiotika mit anthelmintischer Wirkung
GB8804440D0 (en) * 1988-02-25 1988-03-23 Pfizer Ltd Antiparasitic agents
US20060270635A1 (en) * 2005-05-27 2006-11-30 Wallace John L Derivatives of 4- or 5-aminosalicylic acid
CN104543413B (zh) * 2014-12-29 2015-12-02 江西兴鼎科技有限公司 一种阿维拉霉素预混剂的制备方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE434277B (sv) 1976-04-19 1984-07-16 Merck & Co Inc Sett att framstella nya antihelmintiskt verkande foreningar genom odling av streptomyces avermitilis
NZ186851A (en) * 1977-04-11 1984-12-14 Merck & Co Inc Glycosyloxy derivatives of milbemycin and parasiticidal compositions
US4206205A (en) * 1977-10-03 1980-06-03 Merck & Co., Inc. Monosaccharide and aglycone derivatives of C-076
US4199569A (en) * 1977-10-03 1980-04-22 Merck & Co., Inc. Selective hydrogenation products of C-076 compounds and derivatives thereof
NZ188459A (en) * 1977-10-03 1982-09-07 Merck & Co Inc Derivatives of c-076 compounds and pesticidal compositions
US4285963A (en) * 1980-08-07 1981-08-25 Merck & Co., Inc. Novel derivatives of C-076 compounds
US4378353A (en) * 1981-02-17 1983-03-29 Merck & Co., Inc. Novel C-076 compounds

Also Published As

Publication number Publication date
EP0073660A1 (de) 1983-03-09
ES515079A0 (es) 1983-10-16
AU554105B2 (en) 1986-08-07
PT75437A (en) 1982-09-01
NZ201594A (en) 1985-02-28
GR77605B (de) 1984-09-25
ZA826283B (en) 1984-04-25
US4412991A (en) 1983-11-01
EP0073660B1 (de) 1985-10-23
CA1183476A (en) 1985-03-05
DK384282A (da) 1983-03-01
DE3267043D1 (en) 1985-11-28
AU8775282A (en) 1983-03-03
JPS5852300A (ja) 1983-03-28
ES8400144A1 (es) 1983-10-16

Similar Documents

Publication Publication Date Title
AU532187B2 (en) Sugar derivatives of c-076 compounds
ATE16190T1 (de) Derivate von c-076 verbindungen, deren herstellung und benuetzung, und sie enthaltende zusammensetzungen.
IE781963L (en) C-076 compounds.
IL60861A0 (en) Compound obtained from microorganisms of the genus streptomyces, process for the preparation thereof and process for the preparation of anthelmintic and acaricidal compositions containing it
ES476148A1 (es) Un procedimiento para la preparacion de macrolidas
PT74846B (en) Process for preparing compounds of macrolides isolated from the fermentation broth of a strain of streptomyces avermitilis
JPS5759892A (en) Novel derivative of c-076 compound
ATE52781T1 (de) 13-halogenierte milbemycinderivate, ihre herstellung und die sie enthaltenden zusammensetzungen.
JPS5538388A (en) 3*4*55trihydroxypiperidine derivative* its manufacture and its medical use
AU6319480A (en) 2-hydroxyalkyl-3,4,5-trihydroxypiperidines
ZA876833B (en) Novel 23-imino derivatives of 23-keto compounds
GB1467296A (en) Sulphonyl derivatives of erythromycin
ES8308870A1 (es) Procedimiento para la preparacion de derivados de acido 5-(4-fenil-1-piperidinil) metil-2,3-dihidro-2-oxo-1h-imidazol-4-carboxilico.
ES8502700A1 (es) Procedimiento para la fabricacion de derivados de tetrahidrobenzotiazol.
DE3260248D1 (en) Compounds with antibiotic activity, process for their preparation and their use as medicaments
ES8304989A1 (es) Mejoras introducidas en un procedimiento para la preparacion hidroximidatos y tiolhidroximidatos heterobiciclicos y de- rivados ester carbomatos de los mismos.

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee