ZA855552B - Amidine compounds - Google Patents

Amidine compounds

Info

Publication number
ZA855552B
ZA855552B ZA855552A ZA855552A ZA855552B ZA 855552 B ZA855552 B ZA 855552B ZA 855552 A ZA855552 A ZA 855552A ZA 855552 A ZA855552 A ZA 855552A ZA 855552 B ZA855552 B ZA 855552B
Authority
ZA
South Africa
Prior art keywords
amidine compounds
amidine
compounds
Prior art date
Application number
ZA855552A
Other languages
English (en)
Inventor
Setsuro Fujii
Toshiyuki Okutome
Toyoo Nakayama
Shigeki Nunomura
Kimio Sudo
Shinichi Watanabe
Masateru Kurumi
Takuo Aoyama
Original Assignee
Torii & Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Torii & Co Ltd filed Critical Torii & Co Ltd
Publication of ZA855552B publication Critical patent/ZA855552B/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C277/00Preparation of guanidine or its derivatives, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
    • C07C277/08Preparation of guanidine or its derivatives, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups of substituted guanidines
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C279/00Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
    • C07C279/18Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of guanidine groups bound to carbon atoms of six-membered aromatic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/18Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D233/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/04Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D233/28Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/44Nitrogen atoms not forming part of a nitro radical
    • C07D233/50Nitrogen atoms not forming part of a nitro radical with carbocyclic radicals directly attached to said nitrogen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D233/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/88Nitrogen atoms, e.g. allantoin
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D235/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/24Benzimidazoles; Hydrogenated benzimidazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • C07D235/30Nitrogen atoms not forming part of a nitro radical

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
ZA855552A 1984-07-25 1985-07-23 Amidine compounds ZA855552B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP15504584A JPS6133173A (ja) 1984-07-25 1984-07-25 アミジン化合物

Publications (1)

Publication Number Publication Date
ZA855552B true ZA855552B (en) 1986-03-26

Family

ID=15597463

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA855552A ZA855552B (en) 1984-07-25 1985-07-23 Amidine compounds

Country Status (19)

Country Link
US (2) US4777182A (enExample)
EP (1) EP0190356B1 (enExample)
JP (1) JPS6133173A (enExample)
KR (2) KR870001087B1 (enExample)
AU (1) AU567039B2 (enExample)
CA (1) CA1254205A (enExample)
CS (1) CS255891B2 (enExample)
DD (1) DD235637A5 (enExample)
DE (1) DE3582057D1 (enExample)
DK (1) DK169069B1 (enExample)
ES (1) ES8607218A1 (enExample)
FI (1) FI78461C (enExample)
HU (1) HU195769B (enExample)
MX (1) MX160912A (enExample)
NO (1) NO163954C (enExample)
PH (1) PH20585A (enExample)
SU (1) SU1456008A3 (enExample)
WO (1) WO1986000893A1 (enExample)
ZA (1) ZA855552B (enExample)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3824236C1 (enExample) * 1988-07-16 1989-12-28 Heidelberger Druckmaschinen Ag, 6900 Heidelberg, De
CA2032420A1 (en) * 1989-12-22 1991-06-23 Akira Okuyama Guanidinobenzene derivatives
US5238964A (en) * 1990-04-05 1993-08-24 Torii & Co., Ltd. Agent for treatment of cerebrovascular contraction
US5652237A (en) * 1994-09-09 1997-07-29 Warner-Lambert Company 2-substituted-4H-3, 1-benzoxazin-4-ones and benzthiazin-4-ones as inhibitors of complement C1r protease for the treatment of inflammatory processes
US5932603A (en) * 1995-01-05 1999-08-03 Torii Pharmaceutical Co., Ltd. Thrombolytic agents
ATE222583T1 (de) * 1995-01-05 2002-09-15 Torii Pharmaceutical Co Ltd Derivate substituierter amidinonaphthylester
KR100620935B1 (ko) 1998-03-19 2006-09-13 브리스톨-마이어스스퀴브컴파니 용해도가 높은 약물에 대한 2상 서방성 전달 시스템과 방법
WO2001077082A1 (en) * 1999-06-02 2001-10-18 Torii Pharmaceutical Co., Ltd. Naphthalene derivatives
WO2001094299A1 (en) * 2000-06-08 2001-12-13 Shizuoka Coffein Co., Ltd. Benzene derivatives
EP1884236B1 (en) * 2005-05-17 2011-03-02 Santen Pharmaceutical Co., Ltd. Angiogenesis inhibitor containing amine derivative as active ingredient
EP1884237B1 (en) * 2005-05-17 2010-12-08 Santen Pharmaceutical Co., Ltd. Amidino derivatives for use in the prevention or treatment of glaucoma
WO2008058167A2 (en) * 2006-11-07 2008-05-15 Case Western Reserve University Method for treating disorders associated with complement activation
JP6042330B2 (ja) 2010-07-09 2016-12-14 ビーエイチヴィ ファーマ、インコーポレイテッド レモグリフロジンを含めた半減期が短い医薬品のための組合せ即時/遅延放出送達システム
JP6252991B2 (ja) * 2012-07-04 2017-12-27 味の素株式会社 ナファモスタットメシル酸塩の製造方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4292429A (en) * 1978-03-08 1981-09-29 Ciba-Geigy Corporation Imidazole urea and amido compounds
JPS57179146A (en) * 1981-04-28 1982-11-04 Torii Yakuhin Kk Amidine compound
AU527371B2 (en) * 1980-09-16 1983-03-03 Torii & Co., Ltd. Amidine
JPS60130561A (ja) * 1983-12-16 1985-07-12 Torii Yakuhin Kk アミジン誘導体およびそれを含む強心剤

Also Published As

Publication number Publication date
EP0190356A1 (en) 1986-08-13
DK96286A (da) 1986-03-03
DK96286D0 (da) 1986-03-03
NO163954B (no) 1990-05-07
JPH0461868B2 (enExample) 1992-10-02
DE3582057D1 (en) 1991-04-11
CS546385A2 (en) 1987-07-16
US4777182A (en) 1988-10-11
US4820730A (en) 1989-04-11
FI860904A7 (fi) 1986-03-04
JPS6133173A (ja) 1986-02-17
FI860904A0 (fi) 1986-03-04
ES545482A0 (es) 1986-05-16
EP0190356B1 (en) 1991-03-06
CA1254205A (en) 1989-05-16
HUT42433A (en) 1987-07-28
EP0190356A4 (en) 1987-12-09
NO163954C (no) 1990-08-15
PH20585A (en) 1987-02-20
SU1456008A3 (ru) 1989-01-30
DD235637A5 (de) 1986-05-14
CS255891B2 (en) 1988-03-15
KR870001087B1 (ko) 1987-06-04
HU195769B (en) 1988-07-28
FI78461B (fi) 1989-04-28
WO1986000893A1 (fr) 1986-02-13
DK169069B1 (da) 1994-08-08
AU567039B2 (en) 1987-11-05
MX160912A (es) 1990-06-14
NO860865L (no) 1986-04-10
AU4549285A (en) 1986-02-25
FI78461C (fi) 1989-08-10
ES8607218A1 (es) 1986-05-16
KR860700250A (ko) 1986-08-01

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