ZA849337B - N6-(1-and 2-benzocycloalkyl)adenosines - Google Patents
N6-(1-and 2-benzocycloalkyl)adenosinesInfo
- Publication number
- ZA849337B ZA849337B ZA849337A ZA849337A ZA849337B ZA 849337 B ZA849337 B ZA 849337B ZA 849337 A ZA849337 A ZA 849337A ZA 849337 A ZA849337 A ZA 849337A ZA 849337 B ZA849337 B ZA 849337B
- Authority
- ZA
- South Africa
- Prior art keywords
- benzocycloalkyl
- adenosines
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/16—Purine radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/06—Pyrimidine radicals
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Biochemistry (AREA)
- Cardiology (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biotechnology (AREA)
- Heart & Thoracic Surgery (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Psychiatry (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US06/558,144 US4501735A (en) | 1983-12-05 | 1983-12-05 | N6-(1- and 2-benzocycloalkyl) adenosines |
Publications (1)
Publication Number | Publication Date |
---|---|
ZA849337B true ZA849337B (en) | 1986-07-30 |
Family
ID=24228400
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ZA849337A ZA849337B (en) | 1983-12-05 | 1984-11-29 | N6-(1-and 2-benzocycloalkyl)adenosines |
Country Status (18)
Country | Link |
---|---|
US (1) | US4501735A (no) |
EP (1) | EP0144235A3 (no) |
JP (1) | JPS60136592A (no) |
KR (1) | KR850004484A (no) |
AU (1) | AU562690B2 (no) |
CA (1) | CA1230595A (no) |
DK (1) | DK573484A (no) |
ES (1) | ES538238A0 (no) |
FI (1) | FI77667C (no) |
GR (1) | GR81144B (no) |
HU (1) | HUT36482A (no) |
IL (1) | IL73700A (no) |
NO (1) | NO159384C (no) |
NZ (1) | NZ210428A (no) |
OA (1) | OA07883A (no) |
PH (1) | PH21367A (no) |
PT (1) | PT79613B (no) |
ZA (1) | ZA849337B (no) |
Families Citing this family (19)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA1239397A (en) * | 1983-08-01 | 1988-07-19 | James A. Bristol | N.sup.6-substituted adenosines |
DE3406533A1 (de) * | 1984-02-23 | 1985-08-29 | Boehringer Mannheim Gmbh, 6800 Mannheim | Verwendung von adenosin-derivaten als antiallergica und arzneimittel, die diese enthalten |
US4683223A (en) * | 1985-09-09 | 1987-07-28 | Warner-Lambert Company | N6 -Benzopyrano-and benzothiopyrano adenosines and methods of use |
CA1255297A (en) * | 1984-10-26 | 1989-06-06 | Bharat Trivedi | N.sup.6-benzopyrano and benzothiopyrano adenosines |
US4693996A (en) * | 1985-12-23 | 1987-09-15 | Warner-Lambert Company | Method of treating heart failure and medicaments therefor |
US4833273A (en) * | 1986-02-03 | 1989-05-23 | Warner-Lambert Company | Process for the resolution of 1-aminoindanes |
NZ222051A (en) * | 1986-10-06 | 1990-07-26 | Univ Virginia | Solution containing adenosine or hypoxanthine and optionally ribose for heart protection during surgery |
US5063233A (en) * | 1986-11-14 | 1991-11-05 | Ciba-Geigy Corporation | N9 -cyclopentyl-substituted adenine derivatives useful as adenosine receptor agonists |
US4954504A (en) * | 1986-11-14 | 1990-09-04 | Ciba-Geigy Corporation | N9 -cyclopentyl-substituted adenine derivatives having adenosine-2 receptor stimulating activity |
EP0277917A3 (en) * | 1987-02-04 | 1990-03-28 | Ciba-Geigy Ag | Certain adenosine 5'-carboxamide derivatives |
US4968697A (en) * | 1987-02-04 | 1990-11-06 | Ciba-Geigy Corporation | 2-substituted adenosine 5'-carboxamides as antihypertensive agents |
US4837207A (en) * | 1987-05-13 | 1989-06-06 | Warner-Lambert Company | Diastereoisomers of n6 -endo-bicyclo[2.2.1]heptyladenosine as antihypertensives with selective action |
US5410019A (en) * | 1987-09-24 | 1995-04-25 | The Administrators Of The Tulane-Educational Fund | Therapeutic peptides |
US5034381A (en) * | 1988-01-07 | 1991-07-23 | Ciba-Geigy Corporation | 2-(substituted amino) adenosines as antihypertensives |
JPH0725785B2 (ja) * | 1989-01-11 | 1995-03-22 | 日本臓器製薬株式会社 | アデノシン誘導体及び該化合物を有効成分として含有する医薬組成物 |
EP0550631B1 (en) * | 1990-09-25 | 1997-01-02 | Rhone-Poulenc Rorer International (Holdings) Inc. | Compounds having antihypertensive and anti-ischemic properties |
US5561134A (en) * | 1990-09-25 | 1996-10-01 | Rhone-Poulenc Rorer Pharmaceuticals Inc. | Compounds having antihypertensive, cardioprotective, anti-ischemic and antilipolytic properties |
ATE266662T1 (de) | 1998-07-22 | 2004-05-15 | Daiichi Suntory Pharma Co Ltd | Nf-kappa b inhibitoren, die indanderivate als aktiven bestandteil enthalten |
JP2015172077A (ja) * | 2015-06-24 | 2015-10-01 | 中国医学科学院葯物研究所 | N6−置換アデノシン誘導体とn6−置換アデニン誘導体の鎮静、催眠、抗うつ、抗痙攣、抗てんかん、抗パーキンソン病と認知証予防・治療の用途 |
Family Cites Families (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE1670175A1 (de) * | 1966-12-21 | 1970-11-05 | Boehringer Mannheim Gmbh | Verfahren zur Herstellung von Adenosin-Derivaten |
DE1670265A1 (de) * | 1967-08-25 | 1971-01-28 | Boehringer Mannheim Gmbh | 2-Amino-Adenosinderivate und Verfahren zu deren Herstellung |
JPS4826038B1 (no) * | 1970-09-25 | 1973-08-03 | ||
DE2059922A1 (de) * | 1970-12-05 | 1972-06-15 | Boehringer Mannheim Gmbh | Neue N(6)-Aralkyl-adenosin-Derivate und Verfahren zur Herstellung derselben |
DE2136624A1 (de) * | 1971-07-22 | 1973-02-08 | Boehringer Mannheim Gmbh | N (6)-substituierte adenosin-derivate und verfahren zur herstellung derselben |
BE788958A (fr) * | 1971-09-18 | 1973-03-19 | Schering Ag | Derives d'adenosine et leur procede de preparation |
US4090021A (en) * | 1971-10-08 | 1978-05-16 | Schering Aktiengesellschaft | Process for the production of N6 -substituted adenosine nucleotides and products resulting therefrom |
US3922261A (en) * | 1972-06-21 | 1975-11-25 | Merck Patent Gmbh | Adenosine derivative |
DE2230160A1 (de) * | 1972-06-21 | 1974-01-31 | Merck Patent Gmbh | Adenosinderivat |
JPS5046689A (no) * | 1972-07-24 | 1975-04-25 | ||
DE2249397A1 (de) * | 1972-10-09 | 1974-05-02 | Merck Patent Gmbh | Adenosinester und -aether |
DE2406587A1 (de) * | 1974-02-12 | 1975-08-21 | Klinge Co Chem Pharm Fab | Hypolipaemisch wirksame adenosinderivate |
DE3019322A1 (de) * | 1980-05-21 | 1981-12-03 | Merck Patent Gmbh, 6100 Darmstadt | Psychopharmakon sowie verwendung von adenosinderivaten |
US4388308A (en) * | 1980-06-09 | 1983-06-14 | G.D. Searle & Co. | N6 -[(2-Hydroxypropyl)aryl]adenosines |
JPS57171998A (en) * | 1981-04-15 | 1982-10-22 | Fujisawa Pharmaceut Co Ltd | Adenosine derivative and its salt, preparation thereof and medicinal composition containing the same |
DE3406533A1 (de) * | 1984-02-23 | 1985-08-29 | Boehringer Mannheim Gmbh, 6800 Mannheim | Verwendung von adenosin-derivaten als antiallergica und arzneimittel, die diese enthalten |
-
1983
- 1983-12-05 US US06/558,144 patent/US4501735A/en not_active Expired - Fee Related
-
1984
- 1984-11-22 CA CA000468430A patent/CA1230595A/en not_active Expired
- 1984-11-29 ZA ZA849337A patent/ZA849337B/xx unknown
- 1984-11-30 IL IL73700A patent/IL73700A/xx unknown
- 1984-12-03 GR GR81144A patent/GR81144B/el unknown
- 1984-12-03 AU AU36216/84A patent/AU562690B2/en not_active Ceased
- 1984-12-03 FI FI844750A patent/FI77667C/fi not_active IP Right Cessation
- 1984-12-03 DK DK573484A patent/DK573484A/da not_active Application Discontinuation
- 1984-12-04 PH PH31527A patent/PH21367A/en unknown
- 1984-12-04 NO NO844830A patent/NO159384C/no unknown
- 1984-12-04 ES ES538238A patent/ES538238A0/es active Granted
- 1984-12-04 EP EP84308394A patent/EP0144235A3/en not_active Withdrawn
- 1984-12-04 HU HU844477A patent/HUT36482A/hu unknown
- 1984-12-04 NZ NZ210428A patent/NZ210428A/xx unknown
- 1984-12-04 JP JP59255166A patent/JPS60136592A/ja active Pending
- 1984-12-05 PT PT79613A patent/PT79613B/pt unknown
- 1984-12-05 OA OA58460A patent/OA07883A/xx unknown
- 1984-12-05 KR KR1019840007662A patent/KR850004484A/ko not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
IL73700A (en) | 1988-09-30 |
PT79613B (en) | 1986-12-12 |
FI844750A0 (fi) | 1984-12-03 |
PH21367A (en) | 1987-10-15 |
OA07883A (en) | 1986-11-20 |
GR81144B (en) | 1985-04-04 |
DK573484D0 (da) | 1984-12-03 |
NO844830L (no) | 1985-06-06 |
ES8602033A1 (es) | 1985-11-01 |
NZ210428A (en) | 1989-05-29 |
US4501735A (en) | 1985-02-26 |
AU562690B2 (en) | 1987-06-18 |
EP0144235A2 (en) | 1985-06-12 |
FI844750L (fi) | 1985-06-06 |
JPS60136592A (ja) | 1985-07-20 |
NO159384C (no) | 1988-12-21 |
AU3621684A (en) | 1985-06-13 |
IL73700A0 (en) | 1985-02-28 |
EP0144235A3 (en) | 1986-07-30 |
FI77667B (fi) | 1988-12-30 |
NO159384B (no) | 1988-09-12 |
FI77667C (fi) | 1989-04-10 |
ES538238A0 (es) | 1985-11-01 |
KR850004484A (ko) | 1985-07-15 |
CA1230595A (en) | 1987-12-22 |
HUT36482A (en) | 1985-09-30 |
PT79613A (en) | 1985-01-01 |
DK573484A (da) | 1985-06-06 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
GB2136425B (en) | Nucleosides | |
HK126093A (en) | Antiviral guanine derivatives | |
EP0219829A3 (en) | 2-fluoro-arabinofuranosyl purine nucleosides | |
PH21367A (en) | N6-(1-and 2-benzocycloalkyl) adenosines | |
GB2150570B (en) | Novel antiviral agents | |
PT79008B (en) | N6-substituted adenosines | |
GB8320308D0 (en) | Antiviral combinations | |
ZA843152B (en) | Antiviral agents | |
EP0179667A3 (en) | N6-substituted adenosines | |
DE3460387D1 (en) | Cabin | |
GB2143783B (en) | Bulkhead | |
DE3468322D1 (en) | Antiviral agent | |
ZA841521B (en) | Arthropodicides | |
GB8322042D0 (en) | Riveter | |
GB8307669D0 (en) | Spacecraft | |
IE842969L (en) | N6-(1- and 2-benzocycloalkyl) adenosines | |
ZA845311B (en) | N6-substituted adenosines | |
ZA857998B (en) | N6-substituted adenosines | |
GB8315807D0 (en) | Nucleosides | |
ZA844744B (en) | Antiviral agents | |
ZA87120B (en) | N6-substituted adenosines | |
ZA848080B (en) | Purine derivatives | |
GB8404064D0 (en) | Rigid lightweight component | |
GB8322746D0 (en) | Purine derivative | |
IE832845L (en) | Dinucleoside monophosphate |