ZA848651B - Novel polypeptides with an alpha-amylase-inhibiting action,a process for their preparation,their use and pharmaceutical products - Google Patents

Novel polypeptides with an alpha-amylase-inhibiting action,a process for their preparation,their use and pharmaceutical products

Info

Publication number
ZA848651B
ZA848651B ZA848651A ZA848651A ZA848651B ZA 848651 B ZA848651 B ZA 848651B ZA 848651 A ZA848651 A ZA 848651A ZA 848651 A ZA848651 A ZA 848651A ZA 848651 B ZA848651 B ZA 848651B
Authority
ZA
South Africa
Prior art keywords
amylase
alpha
preparation
inhibiting action
pharmaceutical products
Prior art date
Application number
ZA848651A
Other languages
English (en)
Inventor
Laszlo Vertesy
Dominique Tripier
Harald Ritzel
Original Assignee
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Ag filed Critical Hoechst Ag
Publication of ZA848651B publication Critical patent/ZA848651B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/64—Cyclic peptides containing only normal peptide links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/36—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Actinomyces; from Streptomyces (G)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S930/00—Peptide or protein sequence
    • Y10S930/01—Peptide or protein sequence
    • Y10S930/26—Containing cys-cys disulfide bridge between nonadjacent cysteine residues

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
ZA848651A 1984-01-21 1984-11-06 Novel polypeptides with an alpha-amylase-inhibiting action,a process for their preparation,their use and pharmaceutical products ZA848651B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE3402021 1984-01-21

Publications (1)

Publication Number Publication Date
ZA848651B true ZA848651B (en) 1985-06-26

Family

ID=6225535

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA848651A ZA848651B (en) 1984-01-21 1984-11-06 Novel polypeptides with an alpha-amylase-inhibiting action,a process for their preparation,their use and pharmaceutical products

Country Status (17)

Country Link
US (1) US4623714A (fr)
EP (1) EP0151246B1 (fr)
JP (1) JPS60152500A (fr)
KR (1) KR850005454A (fr)
AT (1) ATE56728T1 (fr)
AU (1) AU580973B2 (fr)
CA (1) CA1230841A (fr)
DE (1) DE3483260D1 (fr)
DK (1) DK520784A (fr)
ES (1) ES8602112A1 (fr)
FI (1) FI844289L (fr)
GR (1) GR80840B (fr)
HU (1) HU192495B (fr)
IL (1) IL73472A0 (fr)
NO (1) NO844422L (fr)
PT (1) PT79840B (fr)
ZA (1) ZA848651B (fr)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3508384A1 (de) * 1985-03-08 1986-11-06 Boehringer Mannheim Gmbh, 6800 Mannheim Hemmung humaner speichel- und pankreasamylase durch monoklonale antikoerper
TW381025B (en) * 1993-08-05 2000-02-01 Hoffmann La Roche Pharmaceutical composition containing a glucosidase inhibitor and a lipase inhibitor
KR20060109926A (ko) 2003-11-19 2006-10-23 메타베이시스 테라퓨틱스, 인크. 새로운 인-함유 갑상선 호르몬 모방약들
US7262318B2 (en) * 2004-03-10 2007-08-28 Pfizer, Inc. Substituted heteroaryl- and phenylsulfamoyl compounds
US20050288340A1 (en) * 2004-06-29 2005-12-29 Pfizer Inc Substituted heteroaryl- and phenylsulfamoyl compounds
ATE439347T1 (de) * 2004-11-23 2009-08-15 Warner Lambert Co 7-(2h-pyrazol-3-yl)-3,5-dihydroxy-heptansäure- derivate als hmg-co-a-reductase-inhibitoren zur behandlung von lipidemia
US7741317B2 (en) 2005-10-21 2010-06-22 Bristol-Myers Squibb Company LXR modulators
US7888376B2 (en) 2005-11-23 2011-02-15 Bristol-Myers Squibb Company Heterocyclic CETP inhibitors
ATE547394T1 (de) 2006-12-01 2012-03-15 Bristol Myers Squibb Co N-((3-benzyl)-2,2-(bis-phenyl)-propan-1- aminderivate als cetp-hemmer für die behandlung von atherosklerose und herz-kreislauf- erkrankungen
EA020466B1 (ru) 2007-06-04 2014-11-28 Синерджи Фармасьютикалз Инк. Агонисты гуанилатциклазы, пригодные для лечения желудочно-кишечных нарушений, воспаления, рака и других заболеваний
US8969514B2 (en) 2007-06-04 2015-03-03 Synergy Pharmaceuticals, Inc. Agonists of guanylate cyclase useful for the treatment of hypercholesterolemia, atherosclerosis, coronary heart disease, gallstone, obesity and other cardiovascular diseases
EP2810951B1 (fr) 2008-06-04 2017-03-15 Synergy Pharmaceuticals Inc. Agonistes de guanylate cyclase utile dans le traitement de troubles gastro-intestinaux, d'une inflammation, d'un cancer et d'autres troubles
ES2624828T3 (es) 2008-07-16 2017-07-17 Synergy Pharmaceuticals Inc. Agonistas de la guanilato ciclasa útiles para el tratamiento de trastornos gastrointestinales, inflamación, cáncer y otros
US20120046364A1 (en) 2009-02-10 2012-02-23 Metabasis Therapeutics, Inc. Novel Sulfonic Acid-Containing Thyromimetics, and Methods for Their Use
CA2799708A1 (fr) 2010-05-21 2011-11-24 Pfizer Inc. 2-phenylbenzoylamides
US20130156720A1 (en) 2010-08-27 2013-06-20 Ironwood Pharmaceuticals, Inc. Compositions and methods for treating or preventing metabolic syndrome and related diseases and disorders
US9616097B2 (en) 2010-09-15 2017-04-11 Synergy Pharmaceuticals, Inc. Formulations of guanylate cyclase C agonists and methods of use
US20130345392A1 (en) 2011-03-04 2013-12-26 Pfizer Inc Edn3-like peptides and uses thereof
MY188344A (en) 2012-03-09 2021-12-01 Biotropics Malaysia Berhad Extract formulations of rhodamnia cinerea and uses thereof
CA2905438A1 (fr) 2013-03-15 2014-09-25 Synergy Pharmaceuticals Inc. Agonistes de la guanylate cyclase et leurs utilisations
CA2905435A1 (fr) 2013-03-15 2014-09-25 Synergy Pharmaceuticals Inc. Compositions utiles pour le traitement de troubles gastro-intestinaux
SG11201507496UA (en) 2013-04-17 2015-11-27 Pfizer N-piperidin-3-ylbenzamide derivatives for treating cardiovascular diseases
PT3004138T (pt) 2013-06-05 2024-06-18 Bausch Health Ireland Ltd Agonistas ultrapuros de guanilato ciclase c, método de produção e utilização dos mesmos
CA2959208C (fr) 2014-08-29 2023-09-19 Tes Pharma S.R.L. Derives de pyrimidine et utilisation comme inhibiteurs de .alpha.-amino-beta-carboxymuconate-epsilon-semialdehyde decarboxylase
WO2016055901A1 (fr) 2014-10-08 2016-04-14 Pfizer Inc. Composés d'amide substitué
EP3526199B1 (fr) 2016-10-14 2022-04-13 Tes Pharma S.r.l. Inhibiteurs de la semialdéhyde décarboxylase de l'acide alpha-amino-bêta-carboxymuconique
CA3119509A1 (fr) 2018-11-20 2020-05-28 Tes Pharma S.R.L Inhibiteurs de la semialdehyde decarboxylase de l'acide alpha-amino-beta-carboxymuconique
SG11202107614PA (en) 2019-01-18 2021-08-30 Astrazeneca Ab Pcsk9 inhibitors and methods of use thereof

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2701890C2 (de) * 1977-01-19 1983-08-04 Hoechst Ag, 6230 Frankfurt Peptielischer Glycosidhydrolase-Inhibitor aus einem Streptomyceten und seine Verwendung
DE2716050A1 (de) * 1977-04-09 1978-10-19 Hoechst Ag Alpha-amylase-inhibitor aus einem streptomyceten und verfahren zu seiner gewinnung
ES8207217A1 (es) * 1980-10-09 1982-09-01 Hoechst Ag Procedimiento para la preparacion de un inactivador de alfa-amilasa

Also Published As

Publication number Publication date
ES539678A0 (es) 1985-11-16
PT79840A (en) 1985-02-01
EP0151246B1 (fr) 1990-09-19
DE3483260D1 (de) 1990-10-25
NO844422L (no) 1985-07-22
HU192495B (en) 1987-06-29
ES8602112A1 (es) 1985-11-16
EP0151246A3 (en) 1987-05-27
IL73472A0 (en) 1985-02-28
FI844289A0 (fi) 1984-11-01
GR80840B (en) 1985-02-26
CA1230841A (fr) 1987-12-29
JPS60152500A (ja) 1985-08-10
AU3519084A (en) 1985-07-25
HUT37657A (en) 1986-01-23
US4623714A (en) 1986-11-18
DK520784A (da) 1985-07-22
FI844289L (fi) 1985-07-22
AU580973B2 (en) 1989-02-09
ATE56728T1 (de) 1990-10-15
PT79840B (en) 1986-11-14
EP0151246A2 (fr) 1985-08-14
DK520784D0 (da) 1984-11-01
KR850005454A (ko) 1985-08-26

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