ZA846937B - Derivatives of 4-(3-alkynloxy-2-hydroxy-propyl)-piperazin-1-yl-n-phenyl-acetamide - Google Patents

Derivatives of 4-(3-alkynloxy-2-hydroxy-propyl)-piperazin-1-yl-n-phenyl-acetamide

Info

Publication number
ZA846937B
ZA846937B ZA846937A ZA846937A ZA846937B ZA 846937 B ZA846937 B ZA 846937B ZA 846937 A ZA846937 A ZA 846937A ZA 846937 A ZA846937 A ZA 846937A ZA 846937 B ZA846937 B ZA 846937B
Authority
ZA
South Africa
Prior art keywords
atoms
phenyl
branched
alkyl radical
alkynloxy
Prior art date
Application number
ZA846937A
Other languages
English (en)
Inventor
Michel Combourieu
Jean-Claude Laigle
Jean-Francois Reyjal
Marie-Paule Landes
Original Assignee
Cerm Cent Europ Rech Mauvernay
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cerm Cent Europ Rech Mauvernay filed Critical Cerm Cent Europ Rech Mauvernay
Publication of ZA846937B publication Critical patent/ZA846937B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/14—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D295/145—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/15—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • General Health & Medical Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
ZA846937A 1983-09-15 1984-09-04 Derivatives of 4-(3-alkynloxy-2-hydroxy-propyl)-piperazin-1-yl-n-phenyl-acetamide ZA846937B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8314720A FR2552083B1 (fr) 1983-09-15 1983-09-15 Derives de (alkynyloxy-3 hydroxy-2-propyl)-4 piperazinyl-1 n-phenyl acetamide, leur preparation et leur application en therapeutique

Publications (1)

Publication Number Publication Date
ZA846937B true ZA846937B (en) 1985-04-24

Family

ID=9292262

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA846937A ZA846937B (en) 1983-09-15 1984-09-04 Derivatives of 4-(3-alkynloxy-2-hydroxy-propyl)-piperazin-1-yl-n-phenyl-acetamide

Country Status (14)

Country Link
EP (1) EP0143016B1 (el)
JP (1) JPS60142972A (el)
KR (1) KR850002477A (el)
AT (1) ATE28639T1 (el)
AU (1) AU572888B2 (el)
DE (1) DE3465085D1 (el)
DK (1) DK439384A (el)
ES (2) ES8602724A1 (el)
FI (1) FI77243C (el)
FR (1) FR2552083B1 (el)
GR (1) GR80359B (el)
HU (1) HU192994B (el)
PT (1) PT79214B (el)
ZA (1) ZA846937B (el)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6677336B2 (en) 2000-02-22 2004-01-13 Cv Therapeutics, Inc. Substituted piperazine compounds
US6552023B2 (en) 2000-02-22 2003-04-22 Cv Therapeutics, Inc. Aralkyl substituted piperazine compounds
US6451798B2 (en) 2000-02-22 2002-09-17 Cv Therapeutics, Inc. Substituted alkyl piperazine derivatives
JP3980885B2 (ja) * 2000-02-22 2007-09-26 スィーヴィー セラピューティクス インコーポレイテッド 置換ピペラジン化合物
US6693099B2 (en) * 2000-10-17 2004-02-17 The Procter & Gamble Company Substituted piperazine compounds optionally containing a quinolyl moiety for treating multidrug resistance
US8394954B2 (en) * 2007-03-30 2013-03-12 Council Of Scientific & Industrial Research Benzophenone hybrids as anticancer agents and processes for the preparation thereof
JP6077344B2 (ja) * 2013-03-12 2017-02-08 花王株式会社 ピペラジン誘導体を含む漂白剤組成物

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3951979A (en) * 1972-04-13 1976-04-20 Roland Yves Mauvernary New amino propanediol derivatives
FR2173869B1 (el) * 1972-04-13 1975-12-26 Cerm Cent Europ Rech Mauvernay
FR2403330A1 (fr) * 1977-06-16 1979-04-13 Fabre Sa Pierre Nouveaux derives de benzoyl-2-chloro-4-glycinanilides substitues, leur procede de preparation et leur application en tant que medicaments

Also Published As

Publication number Publication date
ES535899A0 (es) 1985-12-01
FI843617A0 (fi) 1984-09-14
FI843617L (fi) 1985-03-16
HU192994B (en) 1987-08-28
FR2552083B1 (fr) 1986-05-09
DK439384A (da) 1985-03-16
AU572888B2 (en) 1988-05-19
KR850002477A (ko) 1985-05-13
DE3465085D1 (en) 1987-09-03
FI77243C (fi) 1989-02-10
ES8607265A1 (es) 1986-05-16
ATE28639T1 (de) 1987-08-15
PT79214A (en) 1984-10-01
EP0143016A1 (fr) 1985-05-29
GR80359B (en) 1985-01-11
DK439384D0 (da) 1984-09-14
HUT35253A (en) 1985-06-28
PT79214B (en) 1986-08-22
ES8602724A1 (es) 1985-12-01
JPS60142972A (ja) 1985-07-29
FR2552083A1 (fr) 1985-03-22
ES544919A0 (es) 1986-05-16
AU3286184A (en) 1985-03-21
FI77243B (fi) 1988-10-31
EP0143016B1 (fr) 1987-07-29

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