ZA828238B - 1-(3,4,5-trimethoxycinnamoyl)-4-aminocarbonylethyl-substituted pirerazine derivatives and a process for preparation thereof - Google Patents

1-(3,4,5-trimethoxycinnamoyl)-4-aminocarbonylethyl-substituted pirerazine derivatives and a process for preparation thereof

Info

Publication number
ZA828238B
ZA828238B ZA828238A ZA828238A ZA828238B ZA 828238 B ZA828238 B ZA 828238B ZA 828238 A ZA828238 A ZA 828238A ZA 828238 A ZA828238 A ZA 828238A ZA 828238 B ZA828238 B ZA 828238B
Authority
ZA
South Africa
Prior art keywords
pirerazine
trimethoxycinnamoyl
aminocarbonylethyl
derivatives
substituted
Prior art date
Application number
ZA828238A
Other languages
English (en)
Inventor
Yasuo Itho
Hideo Kato
Eiichi Koshinaka
Nobuo Ogawa
Sakae Kurata
Kagari Yamagishi
Original Assignee
Hokuriku Pharmaceutical
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hokuriku Pharmaceutical filed Critical Hokuriku Pharmaceutical
Publication of ZA828238B publication Critical patent/ZA828238B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
    • C07D295/182—Radicals derived from carboxylic acids
    • C07D295/185—Radicals derived from carboxylic acids from aliphatic carboxylic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
ZA828238A 1981-11-19 1982-11-10 1-(3,4,5-trimethoxycinnamoyl)-4-aminocarbonylethyl-substituted pirerazine derivatives and a process for preparation thereof ZA828238B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP56184478A JPS5888370A (ja) 1981-11-19 1981-11-19 １−（３，４，５−トリメトキシシンナモイル）−４−アミノカルボニルエチル置換ピペラジン及びホモピペラジン誘導体、及びその製造方法

Publications (1)

Publication Number Publication Date
ZA828238B true ZA828238B (en) 1983-10-26

Family

ID=16153864

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA828238A ZA828238B (en) 1981-11-19 1982-11-10 1-(3,4,5-trimethoxycinnamoyl)-4-aminocarbonylethyl-substituted pirerazine derivatives and a process for preparation thereof

Country Status (9)

Country Link
US (1) US4478838A (xx)
EP (1) EP0083712A1 (xx)
JP (1) JPS5888370A (xx)
AU (1) AU9074582A (xx)
DK (1) DK517282A (xx)
ES (1) ES8401761A1 (xx)
FR (1) FR2516510A1 (xx)
HU (1) HU186164B (xx)
ZA (1) ZA828238B (xx)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2552762B1 (fr) * 1983-09-30 1986-07-25 Delalande Sa Nouveaux amides piperaziniques et homopiperaziniques derives de l'acide 3,4-dioxymethylene cinnamique, leur procede de preparation et leur application en therapeutique
JPS6172773A (ja) * 1984-09-17 1986-04-14 Terumo Corp ピペラジン誘導体およびこれを含有する血管拡張剤
EP0240233B1 (en) * 1986-03-29 1991-01-23 Suntory Limited Derivatives of benzoquinonyl-phenyl alkanoic acid amide
ATE119156T1 (de) * 1989-04-28 1995-03-15 Sankyo Co N-acryloylpiperazin-derivate, deren herstellung und deren verwendung als paf-antagonisten.
CN101735172B (zh) * 2008-11-04 2012-07-11 北京四环制药有限公司 桂哌齐特一水合物、晶型及其制备方法
CN101979386A (zh) * 2009-12-17 2011-02-23 海南康虹医药科技开发有限公司 制备桂哌齐特游离碱的方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE556791A (xx) *
GB1218591A (en) * 1968-04-03 1971-01-06 Delalande Sa Derivatives of n-(3,4,5-trimethoxy cennamoyl) piperazine and their process of preparation
CH543520A (fr) * 1972-05-30 1973-10-31 Delalande Sa Procédé de préparation de dérivés N'-substitués de la N-(triméthoxycinnamoyl)-pipérazine
FR2278340A1 (fr) * 1974-07-17 1976-02-13 Delalande Sa Nouveau derive de la n-(trimethoxy-3,4,5 cinnamoyl) piperazine, ses sels d'addition d'acides, son procede de preparation et son application en therapeutique
GB1473262A (en) * 1974-11-20 1977-05-11 Delalande Sa Derivatives of n-3,4,5-trimethoxy cinnamoyl-piperazine their process of preparation and their therapeutic application
FR2387971A1 (fr) * 1977-04-19 1978-11-17 Delalande Sa Nouvelles trimethoxy cinnamoyles piperazines, leur procede de preparation et leur application en therapeutique
US4368199A (en) * 1980-01-21 1983-01-11 Delalande S.A. Novel derivatives of 3,4,5-trimethoxy cinnamoyl piperazine, their salts, the process for preparing the same and their application in therapeutics

Also Published As

Publication number Publication date
ES517471A0 (es) 1984-01-01
US4478838A (en) 1984-10-23
JPS5888370A (ja) 1983-05-26
EP0083712A1 (en) 1983-07-20
ES8401761A1 (es) 1984-01-01
HU186164B (en) 1985-06-28
FR2516510A1 (fr) 1983-05-20
AU9074582A (en) 1983-05-26
DK517282A (da) 1983-05-20

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