ZA825480B - Novel androstane derivatives,processes for their manufacture and their use as medicaments - Google Patents

Novel androstane derivatives,processes for their manufacture and their use as medicaments

Info

Publication number
ZA825480B
ZA825480B ZA825480A ZA825480A ZA825480B ZA 825480 B ZA825480 B ZA 825480B ZA 825480 A ZA825480 A ZA 825480A ZA 825480 A ZA825480 A ZA 825480A ZA 825480 B ZA825480 B ZA 825480B
Authority
ZA
South Africa
Prior art keywords
medicaments
manufacture
processes
androstane derivatives
image
Prior art date
Application number
ZA825480A
Other languages
English (en)
Inventor
Dieter Bittler
Henry Laurent
Klaus Nickisch
Rudolf Wiechert
Manfred Albring
Annerose Schleusener
Original Assignee
Schering Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Ag filed Critical Schering Ag
Publication of ZA825480B publication Critical patent/ZA825480B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J21/00—Normal steroids containing carbon, hydrogen, halogen or oxygen having an oxygen-containing hetero ring spiro-condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C07J21/005—Ketals
    • C07J21/006—Ketals at position 3
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C07J1/0003—Androstane derivatives
    • C07J1/0033—Androstane derivatives substituted in position 17 alfa and 17 beta
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J53/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton has been modified by condensation with a carbocyclic rings or by formation of an additional ring by means of a direct link between two ring carbon atoms, including carboxyclic rings fused to the cyclopenta(a)hydrophenanthrene skeleton are included in this class
    • C07J53/002—Carbocyclic rings fused
    • C07J53/004—3 membered carbocyclic rings
    • C07J53/005—3 membered carbocyclic rings in position 12
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J53/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton has been modified by condensation with a carbocyclic rings or by formation of an additional ring by means of a direct link between two ring carbon atoms, including carboxyclic rings fused to the cyclopenta(a)hydrophenanthrene skeleton are included in this class
    • C07J53/002—Carbocyclic rings fused
    • C07J53/004—3 membered carbocyclic rings
    • C07J53/008—3 membered carbocyclic rings in position 15/16
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
    • C07J71/0005—Oxygen-containing hetero ring
    • C07J71/001—Oxiranes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Dermatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
ZA825480A 1981-07-29 1982-07-29 Novel androstane derivatives,processes for their manufacture and their use as medicaments ZA825480B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19813130644 DE3130644A1 (de) 1981-07-29 1981-07-29 Neue androstan-derivate, verfahren zu ihrer herstellung und pharmazeutische praeparate, die diese verbindungen enthalten

Publications (1)

Publication Number Publication Date
ZA825480B true ZA825480B (en) 1983-11-30

Family

ID=6138450

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA825480A ZA825480B (en) 1981-07-29 1982-07-29 Novel androstane derivatives,processes for their manufacture and their use as medicaments

Country Status (17)

Country Link
US (2) US4457925A (ru)
EP (1) EP0071153B1 (ru)
JP (1) JPS5849400A (ru)
AT (1) ATE22086T1 (ru)
AU (1) AU558412B2 (ru)
CA (1) CA1210754A (ru)
DE (2) DE3130644A1 (ru)
DK (1) DK164325B (ru)
ES (1) ES514492A0 (ru)
FI (1) FI78110C (ru)
GB (1) GB2104899B (ru)
GR (1) GR76872B (ru)
IE (1) IE53711B1 (ru)
IL (1) IL66311A (ru)
NO (1) NO159661C (ru)
PT (1) PT75334B (ru)
ZA (1) ZA825480B (ru)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3331824A1 (de) * 1983-09-01 1985-03-21 Schering AG, Berlin und Bergkamen, 1000 Berlin Verfahren zur herstellung von 17(alpha)-acyloxy-6-chlor-1(alpha),2(alpha)-methylen-3,20-dionen
DE3347126A1 (de) * 1983-12-22 1985-07-11 Schering AG, 1000 Berlin und 4709 Bergkamen 11ss-aryl-estradiene, deren herstellung und diese enthaltende pharmazeutische praeparate
US4720489A (en) * 1984-10-15 1988-01-19 Douglas Shander Hair growth modification with ornithine decarboxylase inhibitors
JPS61286185A (ja) * 1985-06-13 1986-12-16 Yoshizo Koishi 刻印装置
DE3824247A1 (de) * 1988-07-13 1990-01-18 Schering Ag Neue androstan-derivate
GB9021546D0 (en) * 1990-10-04 1990-11-21 Beecham Group Plc Novel composition
DE4102244A1 (de) * 1991-01-24 1992-07-30 Schering Ag 14,16ss-ethano-15ss, 16(pfeil hoch)1(pfeil hoch)-cyclo-14ss-estra-1,3,5(10)-triene
US6743419B1 (en) 1992-12-22 2004-06-01 The Gillette Company Method of reducing hair growth employing sulfhydryl active compounds
US5411991A (en) * 1992-12-22 1995-05-02 Shander; Douglas Method of reducing hair growth employing sulfhydryl active compounds
EP1615944A4 (en) * 2003-04-01 2010-08-11 Harbor Biosciences Inc ANTI-ORANGE PROBLEMS WITH MARGINAL AGONIST EFFECT AND METHOD OF USE
US8084446B2 (en) 2005-04-26 2011-12-27 Eric Marchewitz Use of DHEA derivatives for enhancing physical performance
US20130123523A1 (en) * 2011-11-10 2013-05-16 Klaus Nickisch Methods for the preparation of etonogestrel and desogestrel

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR7871M (ru) * 1968-11-13 1970-04-27
CH631462A5 (de) * 1976-03-05 1982-08-13 Schering Ag Verfahren zur herstellung von neuen steroiden der androstan- oder oestranreihe.
DE2644427A1 (de) * 1976-09-30 1978-04-06 Schering Ag 17 beta-hydroxy-17 alpha-(3-acyloxypropyl)-4.6-androstadien-3-one und deren salze
DE2722706A1 (de) * 1977-05-16 1978-12-07 Schering Ag 15.16-methylen-androsta-4.15-dien- 3-one und verfahren zu ihrer herstellung
ES469510A1 (es) * 1977-05-16 1978-12-01 Schering Ag Procedimiento para la preparacion de 17beta hidroxi-4-an- drosten-3-onas.

Also Published As

Publication number Publication date
EP0071153A1 (de) 1983-02-09
JPS5849400A (ja) 1983-03-23
FI78110C (fi) 1989-06-12
PT75334A (de) 1982-08-01
PT75334B (de) 1984-07-31
FI822658L (fi) 1983-01-30
AU8643982A (en) 1984-10-18
ES8305003A1 (es) 1983-04-16
NO159661B (no) 1988-10-17
US4587235A (en) 1986-05-06
DE3130644A1 (de) 1983-02-17
JPH033678B2 (ru) 1991-01-21
IL66311A0 (en) 1982-11-30
ATE22086T1 (de) 1986-09-15
FI78110B (fi) 1989-02-28
GR76872B (ru) 1984-09-04
FI822658A0 (fi) 1982-07-29
GB2104899A (en) 1983-03-16
GB2104899B (en) 1985-01-30
NO822596L (no) 1983-01-31
IL66311A (en) 1986-03-31
NO159661C (no) 1989-01-25
IE821824L (en) 1983-01-29
DE3273186D1 (en) 1986-10-16
ES514492A0 (es) 1983-04-16
DK327082A (da) 1983-01-30
IE53711B1 (en) 1989-01-18
DK164325B (da) 1992-06-09
EP0071153B1 (de) 1986-09-10
AU558412B2 (en) 1987-01-29
US4457925A (en) 1984-07-03
CA1210754A (en) 1986-09-02

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