ZA818370B - N-pyrimidinyl-carbamic acid esters, their preparation, and drugs containing these compounds - Google Patents

N-pyrimidinyl-carbamic acid esters, their preparation, and drugs containing these compounds

Info

Publication number
ZA818370B
ZA818370B ZA818370A ZA818370A ZA818370B ZA 818370 B ZA818370 B ZA 818370B ZA 818370 A ZA818370 A ZA 818370A ZA 818370 A ZA818370 A ZA 818370A ZA 818370 B ZA818370 B ZA 818370B
Authority
ZA
South Africa
Prior art keywords
pyrimidinyl
compounds
preparation
acid esters
carbamic acid
Prior art date
Application number
ZA818370A
Other languages
English (en)
Inventor
P Scharwaechter
K Gutsche
F Kohlmann
H Beck
Original Assignee
Basf Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Basf Ag filed Critical Basf Ag
Publication of ZA818370B publication Critical patent/ZA818370B/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/48Two nitrogen atoms
    • C07D239/49Two nitrogen atoms with an aralkyl radical, or substituted aralkyl radical, attached in position 5, e.g. trimethoprim
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/63Compounds containing para-N-benzenesulfonyl-N-groups, e.g. sulfanilamide, p-nitrobenzenesulfonyl hydrazide
    • A61K31/635Compounds containing para-N-benzenesulfonyl-N-groups, e.g. sulfanilamide, p-nitrobenzenesulfonyl hydrazide having a heterocyclic ring, e.g. sulfadiazine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Oncology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
ZA818370A 1980-12-04 1981-12-03 N-pyrimidinyl-carbamic acid esters, their preparation, and drugs containing these compounds ZA818370B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19803045720 DE3045720A1 (de) 1980-12-04 1980-12-04 N-pyrimidinyl-carbaminsaeureester, verfahren zu ihrer herstellung und diese enthaltende arzneimittel

Publications (1)

Publication Number Publication Date
ZA818370B true ZA818370B (en) 1982-11-24

Family

ID=6118292

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA818370A ZA818370B (en) 1980-12-04 1981-12-03 N-pyrimidinyl-carbamic acid esters, their preparation, and drugs containing these compounds

Country Status (12)

Country Link
US (1) US4386084A (fi)
EP (1) EP0053695A3 (fi)
JP (1) JPS57122068A (fi)
AU (1) AU7821981A (fi)
DE (1) DE3045720A1 (fi)
DK (1) DK535781A (fi)
ES (1) ES8300099A1 (fi)
FI (1) FI813845L (fi)
GR (1) GR75115B (fi)
NO (1) NO814138L (fi)
PT (1) PT74077B (fi)
ZA (1) ZA818370B (fi)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5707996A (en) * 1995-11-06 1998-01-13 Macleod Pharmaceuticals, Inc. Pharmaceutical solution and methods for preparation thereof
EP1538907A4 (en) * 2002-07-02 2008-12-24 Southern Res Inst FTSZ-HEMMER AND ITS USE
PT1725540E (pt) 2004-03-05 2012-11-29 Hoffmann La Roche Diaminopirimidinas como antagonistas de p2x3 e p2x2/3
EP1924565B1 (en) * 2005-09-01 2016-09-14 F.Hoffmann-La Roche Ag Diaminopyrimidines as p2x3 and p3x2/3 modulators
JP4850911B2 (ja) * 2005-09-01 2012-01-11 エフ.ホフマン−ラ ロシュ アーゲー P2x3およびp2x2/3モジュレーターとしてのジアミノピリミジン
CA2620129C (en) * 2005-09-01 2014-12-23 F. Hoffmann-La Roche Ag Diaminopyrimidines as p2x3 and p2x2/3 modulators

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3919229A (en) * 1973-07-19 1975-11-11 Labaz Pyrimidine derivatives and process for preparing the same
BE850974A (fr) * 1977-02-01 1977-05-31 Andreu Sa Dr Nouveaux imides de trimethoprim et leur obtention
DE2709634A1 (de) * 1977-03-05 1978-09-07 Basf Ag Benzylpyrimidine, verfahren zu ihrer herstellung und diese enthaltende arzneimittel
DE2730468A1 (de) * 1977-07-06 1979-01-18 Basf Ag Neue n-pyrimidinyl-imidsaeureester, verfahren zu ihrer herstellung und diese enthaltende arzneimittel
DE2730467A1 (de) * 1977-07-06 1979-01-18 Basf Ag Benzylpyrimidine, verfahren zu ihrer herstellung und diese enthaltende arzneimittel
DE2732029A1 (de) * 1977-07-15 1979-02-01 Basf Ag Neue amidino-benzylpyrimidine, verfahren zu ihrer herstellung und diese enthaltende arzneimittel

Also Published As

Publication number Publication date
JPS57122068A (en) 1982-07-29
FI813845L (fi) 1982-06-05
AU7821981A (en) 1982-06-10
ES507682A0 (es) 1982-10-01
DK535781A (da) 1982-06-05
US4386084A (en) 1983-05-31
PT74077B (de) 1983-05-11
NO814138L (no) 1982-06-07
DE3045720A1 (de) 1982-07-08
PT74077A (de) 1982-01-01
EP0053695A2 (de) 1982-06-16
GR75115B (fi) 1984-07-13
EP0053695A3 (de) 1982-12-15
ES8300099A1 (es) 1982-10-01

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