ZA817787B - Indolinone derivatives,processes for their preparation and pharmaceutical compositions containing these - Google Patents

Indolinone derivatives,processes for their preparation and pharmaceutical compositions containing these

Info

Publication number
ZA817787B
ZA817787B ZA817787A ZA817787A ZA817787B ZA 817787 B ZA817787 B ZA 817787B ZA 817787 A ZA817787 A ZA 817787A ZA 817787 A ZA817787 A ZA 817787A ZA 817787 B ZA817787 B ZA 817787B
Authority
ZA
South Africa
Prior art keywords
processes
preparation
pharmaceutical compositions
compositions containing
indolinone derivatives
Prior art date
Application number
ZA817787A
Other languages
English (en)
Inventor
Erich Mueller
Josef Nickl
Josef Roch
Berthold Narr
Walter Haarmann
Johannes Maximili Weisenberger
Original Assignee
Thomae Gmbh Dr K
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Thomae Gmbh Dr K filed Critical Thomae Gmbh Dr K
Publication of ZA817787B publication Critical patent/ZA817787B/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04Indoles; Hydrogenated indoles
    • C07D209/30Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
    • C07D209/32Oxygen atoms
    • C07D209/34Oxygen atoms in position 2
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Diabetes (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Indole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
ZA817787A 1980-11-12 1981-11-11 Indolinone derivatives,processes for their preparation and pharmaceutical compositions containing these ZA817787B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE3042632 1980-11-12

Publications (1)

Publication Number Publication Date
ZA817787B true ZA817787B (en) 1983-07-27

Family

ID=6116579

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA817787A ZA817787B (en) 1980-11-12 1981-11-11 Indolinone derivatives,processes for their preparation and pharmaceutical compositions containing these

Country Status (29)

Country Link
US (1) US4629733A (da)
JP (1) JPS57114569A (da)
KR (1) KR880002227B1 (da)
AT (1) AT375923B (da)
AU (1) AU547929B2 (da)
BE (1) BE891103A (da)
CA (1) CA1183848A (da)
CH (1) CH652120A5 (da)
DD (1) DD201889A5 (da)
DK (1) DK154138C (da)
ES (2) ES8206470A1 (da)
FI (1) FI75806C (da)
FR (1) FR2493841A1 (da)
GB (1) GB2098595B (da)
GR (1) GR81330B (da)
HU (1) HU183680B (da)
IE (1) IE52107B1 (da)
IL (1) IL64252A (da)
IT (1) IT1171624B (da)
LU (1) LU83744A1 (da)
NL (1) NL8105100A (da)
NO (1) NO156167C (da)
NZ (1) NZ198941A (da)
PL (1) PL134525B1 (da)
PT (1) PT73969B (da)
SE (1) SE452156B (da)
SU (1) SU1107759A3 (da)
YU (1) YU41995B (da)
ZA (1) ZA817787B (da)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0089394A1 (en) * 1982-03-23 1983-09-28 Sterling Drug Inc. 1-H-Indole-2,3-dione derivatives and preparation thereof
US5272145A (en) * 1989-08-22 1993-12-21 Merck Frosst Canada, Inc. (Quinolin-2-ylmethoxy)indoles as inhibitors of the biosynthesis of leukotrienes
US5204344A (en) * 1989-08-22 1993-04-20 Merck Frosst Canada, Inc. (Quinolin-2-ylmethoxy)indoles as inhibitors of the biosynthesis of leukotrienes
GB9008605D0 (en) * 1990-04-17 1990-06-13 Smith Kline French Lab Process
US5190968A (en) * 1991-09-30 1993-03-02 Merck Frosst Canada, Inc. (Polycyclic-arylmethoxy) indoles as inhibitors of leukotriene biosynthesis
US5290798A (en) * 1991-09-30 1994-03-01 Merck Frosst Canada, Inc. (hetero-arylmethoxy)indoles as inhibitors of leukotriene biosynthesis
US5389650A (en) * 1991-09-30 1995-02-14 Merck Frosst Canada, Inc. (Azaarylmethoxy)indoles as inhibitors of leukotriene biosynthesis
US5308850A (en) * 1991-09-30 1994-05-03 Merck Frosst Canada, Inc. (Bicyclic-hetero-arylmethoxy)indoles as inhibitors of leukotriene biosynthesis
US5374635A (en) * 1993-03-29 1994-12-20 Merck Frosst Canada, Inc. Furo[3,2-b]pyridines and thieno[3,2-b]pyridines as inhibitors of leukotriene biosynthesis

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AT330169B (de) * 1971-06-24 1976-06-25 Sandoz Ag Verfahren zur herstellung neuer oxindole und ihrer salze
SU843739A3 (ru) * 1978-02-17 1981-06-30 Карл Томэ Гмбх (Фирма) Способ получени карбостириловыхили ОКСиНдОлОВыХ пРОизВОдНыХ
DE2853314A1 (de) * 1978-12-09 1980-06-26 Thomae Gmbh Dr K Neue carbostyril- und oxindolderivate, ihre herstellung und ihre verwendung als arzneimittel
US4329347A (en) * 1978-02-17 1982-05-11 Boehringer Ingelheim Gmbh Cardiotonic and antithrombotic sulfur-containing derivatives of carbostyril
US4442111A (en) * 1981-07-25 1984-04-10 Dr. Karl Thomae Gesellschaft Mit Beschrankter Haftung Antithrombotic sulfimino and sulfoximino indolinones-2

Also Published As

Publication number Publication date
PT73969A (de) 1981-12-01
BE891103A (fr) 1982-05-12
DK496781A (da) 1982-05-13
YU266681A (en) 1983-10-31
DK154138C (da) 1989-04-17
SE8106704L (sv) 1982-05-13
LU83744A1 (de) 1983-04-13
SE452156B (sv) 1987-11-16
HU183680B (en) 1984-05-28
DK154138B (da) 1988-10-17
PL233774A1 (da) 1982-12-20
FI75806B (fi) 1988-04-29
ES507015A0 (es) 1982-08-16
FI813561L (fi) 1982-05-13
NO813821L (no) 1982-05-13
ES511834A0 (es) 1983-02-16
JPS57114569A (en) 1982-07-16
AU547929B2 (en) 1985-11-14
IL64252A0 (en) 1982-02-28
NL8105100A (nl) 1982-06-01
FR2493841A1 (fr) 1982-05-14
GB2098595A (en) 1982-11-24
IT1171624B (it) 1987-06-10
IT8149602A0 (it) 1981-10-30
PT73969B (de) 1983-11-23
FI75806C (fi) 1988-08-08
SU1107759A3 (ru) 1984-08-07
YU41995B (en) 1988-04-30
DD201889A5 (de) 1983-08-17
US4629733A (en) 1986-12-16
GB2098595B (en) 1984-09-05
ES8206470A1 (es) 1982-08-16
FR2493841B1 (da) 1984-03-30
ATA478981A (de) 1984-02-15
KR830007554A (ko) 1983-10-21
IE52107B1 (en) 1987-06-24
NO156167B (no) 1987-04-27
ES8304081A1 (es) 1983-02-16
NZ198941A (en) 1984-10-19
AT375923B (de) 1984-09-25
IE812640L (en) 1982-05-12
GR81330B (da) 1984-12-11
NO156167C (no) 1987-08-05
CA1183848A (en) 1985-03-12
PL134525B1 (en) 1985-08-31
KR880002227B1 (ko) 1988-10-20
CH652120A5 (de) 1985-10-31
AU7739081A (en) 1982-05-20
IL64252A (en) 1985-02-28

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