ZA815540B - Heterocyclic compounds - Google Patents
Heterocyclic compoundsInfo
- Publication number
- ZA815540B ZA815540B ZA815540A ZA815540A ZA815540B ZA 815540 B ZA815540 B ZA 815540B ZA 815540 A ZA815540 A ZA 815540A ZA 815540 A ZA815540 A ZA 815540A ZA 815540 B ZA815540 B ZA 815540B
- Authority
- ZA
- South Africa
- Prior art keywords
- heterocyclic compounds
- heterocyclic
- compounds
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/44—Iso-indoles; Hydrogenated iso-indoles
- C07D209/48—Iso-indoles; Hydrogenated iso-indoles with oxygen atoms in positions 1 and 3, e.g. phthalimide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C243/00—Compounds containing chains of nitrogen atoms singly-bound to each other, e.g. hydrazines, triazanes
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C251/00—Compounds containing nitrogen atoms doubly-bound to a carbon skeleton
- C07C251/72—Hydrazones
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C255/00—Carboxylic acid nitriles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/14—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
- C07D209/16—Tryptamines
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Public Health (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Pain & Pain Management (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Indole Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB8026286 | 1980-08-12 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA815540B true ZA815540B (en) | 1983-03-30 |
Family
ID=10515410
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA815540A ZA815540B (en) | 1980-08-12 | 1981-08-11 | Heterocyclic compounds |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US4650810A (it) |
| JP (1) | JPS5764669A (it) |
| AU (1) | AU548467B2 (it) |
| BE (1) | BE889929A (it) |
| CA (1) | CA1169428A (it) |
| CH (1) | CH651551A5 (it) |
| DE (1) | DE3131728A1 (it) |
| DK (1) | DK157920C (it) |
| ES (5) | ES504693A0 (it) |
| FR (1) | FR2488607A1 (it) |
| IE (1) | IE51491B1 (it) |
| IT (1) | IT1171449B (it) |
| NL (1) | NL8103769A (it) |
| NZ (1) | NZ197996A (it) |
| SE (1) | SE454880B (it) |
| ZA (1) | ZA815540B (it) |
Families Citing this family (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1170387B (it) * | 1982-06-07 | 1987-06-03 | Glaxo Group Ltd | Composti eterociclici, procedimento per prepararli e composizioni farmaceutiche che li contengono |
| GB8332435D0 (en) * | 1983-12-06 | 1984-01-11 | Glaxo Group Ltd | Chemical compounds |
| GB8419575D0 (en) * | 1984-08-01 | 1984-09-05 | Glaxo Group Ltd | Chemical compounds |
| DE3678805D1 (de) * | 1985-11-08 | 1991-05-23 | Glaxo Group Ltd | Indolderivate. |
| GB8530507D0 (en) * | 1985-12-11 | 1986-01-22 | Glaxo Group Plc | Chemical compounds |
| US5270333A (en) * | 1986-01-28 | 1993-12-14 | Glaxo Group Limited | Indole derivatives |
| GB8607824D0 (en) * | 1986-03-27 | 1986-04-30 | Glaxo Group Ltd | Chemical compounds |
| PT97888B (pt) * | 1990-06-07 | 1998-12-31 | Zeneca Ltd | Processo para a preparacao de compostos heterociclicos derivados de indol e de composicoes farmaceuticas que os contem |
| CZ283018B6 (cs) * | 1991-02-01 | 1997-12-17 | Merck Sharp And Dohme Limited | Deriváty imidazolu, triazolu a tetrazolu a farmaceutické přípravky na jejich bázi |
| US5254383A (en) * | 1992-09-14 | 1993-10-19 | Allied-Signal Inc. | Composites having improved penetration resistance and articles fabricated from same |
| FR2701026B1 (fr) * | 1993-02-02 | 1995-03-31 | Adir | Nouveaux dérivés de l'indole, de l'indazole et du benzisoxazole, leur procédé de préparation et les compositions pharmaceutiques qui les contiennent. |
| US5468768A (en) * | 1994-01-06 | 1995-11-21 | Bristol-Myers Squibb Company | Antimigraine derivatives of indolylcycloalkanylamines |
| ES2084560B1 (es) * | 1994-03-09 | 1997-01-16 | Almirall Lab | Procedimiento de preparacion de derivados el indol. |
| US5891885A (en) * | 1996-10-09 | 1999-04-06 | Algos Pharmaceutical Corporation | Method for treating migraine |
| US20030096379A1 (en) * | 2001-03-28 | 2003-05-22 | Kilgore James L. | Method for producing tryptamine derivatives |
| US6685951B2 (en) | 2001-07-05 | 2004-02-03 | R. T. Alamo Ventures I, Inc. | Administration of dihydroergotamine as a sublingual spray or aerosol for the treatment of migraine |
| US20030017175A1 (en) * | 2001-07-05 | 2003-01-23 | R.T. Alamo Ventures I, Inc. | Sublingual administration of dihydroergotamine for the treatment of migraine |
| US20030198669A1 (en) * | 2001-07-05 | 2003-10-23 | R.T. Alamo Ventures I, Llc | Compositions and methods for rapid dissolving formulations of dihydroergotamine and caffeine for the treatment of migraine |
| CA2508290C (en) * | 2002-12-20 | 2017-02-28 | Ciba Specialty Chemicals Holding Inc. | Synthesis of amines and intermediates for the synthesis thereof |
| JP5825757B2 (ja) * | 2007-02-11 | 2015-12-02 | マップ・ファーマシューティカルズ・インコーポレイテッド | 副作用プロファイルを最小限にしながら片頭痛の迅速な緩和を可能にするｄｈｅの治療上の投与方法 |
| CL2008000838A1 (es) * | 2007-03-23 | 2008-10-10 | Neuraxon Inc | Compuestos derivados de quinolina y tetrahidroquinolina, con actividad inhibidora nos; composicion farmaceutica que comprende a dichos compuestos; y su uso para tratar un dolor de cabeza tal como migrana, dolor cronico, desordenes del sistema nervios |
| JP5164972B2 (ja) | 2007-03-29 | 2013-03-21 | 第一三共株式会社 | ｃＰＬＡ２阻害活性を有するインドール誘導体およびその用途並びに製造方法 |
| WO2010151804A1 (en) * | 2009-06-26 | 2010-12-29 | Map Pharmaceuticals, Inc. | Administration of dihydroergotamine mesylate particles using a metered dose inhaler |
| EP3628325A1 (en) | 2011-07-22 | 2020-04-01 | The University of Chicago | Treatments for migraine and related disorders |
| EP2935280A4 (en) | 2012-12-21 | 2016-05-25 | Map Pharmaceuticals Inc | 8'-HYDROXY-DIHYDROERGOTAMINE COMPOUNDS AND COMPOSITIONS |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3182071A (en) * | 1961-06-27 | 1965-05-04 | Warner Lambert Pharmaceutical | Acylated indole derivatives |
| US3472870A (en) * | 1966-08-29 | 1969-10-14 | Mead Johnson & Co | Sulfonamidotryptamines |
| ZA795239B (en) * | 1978-10-12 | 1980-11-26 | Glaxo Group Ltd | Heterocyclic compounds |
-
1981
- 1981-08-11 NZ NZ197996A patent/NZ197996A/en unknown
- 1981-08-11 SE SE8104781A patent/SE454880B/sv not_active IP Right Cessation
- 1981-08-11 BE BE0/205642A patent/BE889929A/fr not_active IP Right Cessation
- 1981-08-11 IE IE1830/81A patent/IE51491B1/en unknown
- 1981-08-11 ZA ZA815540A patent/ZA815540B/xx unknown
- 1981-08-11 FR FR8115513A patent/FR2488607A1/fr active Granted
- 1981-08-11 NL NL8103769A patent/NL8103769A/nl not_active Application Discontinuation
- 1981-08-11 ES ES504693A patent/ES504693A0/es active Granted
- 1981-08-11 CH CH5159/81A patent/CH651551A5/fr not_active IP Right Cessation
- 1981-08-11 IT IT49084/81A patent/IT1171449B/it active
- 1981-08-11 DE DE19813131728 patent/DE3131728A1/de active Granted
- 1981-08-11 AU AU73994/81A patent/AU548467B2/en not_active Ceased
- 1981-08-11 DK DK357081A patent/DK157920C/da not_active IP Right Cessation
- 1981-08-12 CA CA000383670A patent/CA1169428A/en not_active Expired
- 1981-08-12 JP JP56125411A patent/JPS5764669A/ja active Granted
-
1982
- 1982-07-13 ES ES513933A patent/ES513933A0/es active Granted
-
1983
- 1983-01-26 US US06/461,233 patent/US4650810A/en not_active Expired - Fee Related
- 1983-03-18 ES ES520785A patent/ES520785A0/es active Granted
- 1983-03-18 ES ES520783A patent/ES520783A0/es active Granted
- 1983-03-18 ES ES520784A patent/ES8500902A1/es not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| CA1169428A (en) | 1984-06-19 |
| DE3131728A1 (de) | 1982-03-11 |
| FR2488607A1 (fr) | 1982-02-19 |
| SE8104781L (sv) | 1982-02-13 |
| CH651551A5 (fr) | 1985-09-30 |
| FR2488607B1 (it) | 1984-11-16 |
| ES8301210A1 (es) | 1982-12-01 |
| US4650810A (en) | 1987-03-17 |
| ES8402268A1 (es) | 1984-01-16 |
| IE51491B1 (en) | 1987-01-07 |
| DK157920B (da) | 1990-03-05 |
| NL8103769A (nl) | 1982-03-01 |
| ES513933A0 (es) | 1984-01-16 |
| JPS5764669A (en) | 1982-04-19 |
| JPH0247462B2 (it) | 1990-10-19 |
| SE454880B (sv) | 1988-06-06 |
| IT8149084A0 (it) | 1981-08-11 |
| NZ197996A (en) | 1985-08-16 |
| AU548467B2 (en) | 1985-12-12 |
| ES8500903A1 (es) | 1984-11-01 |
| ES8504706A1 (es) | 1985-05-01 |
| ES520784A0 (es) | 1984-11-01 |
| BE889929A (fr) | 1982-02-11 |
| ES520783A0 (es) | 1985-05-01 |
| ES8500902A1 (es) | 1984-11-01 |
| IE811830L (en) | 1982-02-12 |
| DK157920C (da) | 1990-08-06 |
| ES504693A0 (es) | 1982-12-01 |
| ES520785A0 (es) | 1984-11-01 |
| IT1171449B (it) | 1987-06-10 |
| AU7399481A (en) | 1982-02-18 |
| DK357081A (da) | 1982-02-13 |
| DE3131728C2 (it) | 1992-04-30 |
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