ZA814606B - New benzisoselenazolones process for producing the same and pharmaceutical preparations containing the same - Google Patents

New benzisoselenazolones process for producing the same and pharmaceutical preparations containing the same

Info

Publication number
ZA814606B
ZA814606B ZA814606A ZA814606A ZA814606B ZA 814606 B ZA814606 B ZA 814606B ZA 814606 A ZA814606 A ZA 814606A ZA 814606 A ZA814606 A ZA 814606A ZA 814606 B ZA814606 B ZA 814606B
Authority
ZA
South Africa
Prior art keywords
same
benzisoselenazolones
producing
new
pharmaceutical preparations
Prior art date
Application number
ZA814606A
Other languages
English (en)
Inventor
A Welter
L Christiaens
Peitz F Wirtz
Original Assignee
Nattermann A & Cie
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nattermann A & Cie filed Critical Nattermann A & Cie
Publication of ZA814606B publication Critical patent/ZA814606B/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D421/00Heterocyclic compounds containing two or more hetero rings, at least one ring having selenium, tellurium, or halogen atoms as ring hetero atoms
    • C07D421/02Heterocyclic compounds containing two or more hetero rings, at least one ring having selenium, tellurium, or halogen atoms as ring hetero atoms containing two hetero rings
    • C07D421/04Heterocyclic compounds containing two or more hetero rings, at least one ring having selenium, tellurium, or halogen atoms as ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C391/00Compounds containing selenium
    • C07C391/02Compounds containing selenium having selenium atoms bound to carbon atoms of six-membered aromatic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D293/00Heterocyclic compounds containing rings having nitrogen and selenium or nitrogen and tellurium, with or without oxygen or sulfur atoms, as the ring hetero atoms
    • C07D293/10Heterocyclic compounds containing rings having nitrogen and selenium or nitrogen and tellurium, with or without oxygen or sulfur atoms, as the ring hetero atoms condensed with carbocyclic rings or ring systems
    • C07D293/12Selenazoles; Hydrogenated selenazoles
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D317/00Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/44Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D317/46Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D317/48Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring
    • C07D317/62Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to atoms of the carbocyclic ring
    • C07D317/66Nitrogen atoms not forming part of a nitro radical
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D517/00Heterocyclic compounds containing in the condensed system at least one hetero ring having selenium, tellurium, or halogen atoms as ring hetero atoms
    • C07D517/02Heterocyclic compounds containing in the condensed system at least one hetero ring having selenium, tellurium, or halogen atoms as ring hetero atoms in which the condensed system contains two hetero rings
    • C07D517/04Ortho-condensed systems
ZA814606A 1980-07-17 1981-07-07 New benzisoselenazolones process for producing the same and pharmaceutical preparations containing the same ZA814606B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19803027075 DE3027075A1 (de) 1980-07-17 1980-07-17 Benzisoselenazolone, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische praeparate

Publications (1)

Publication Number Publication Date
ZA814606B true ZA814606B (en) 1982-07-28

Family

ID=6107417

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA814606A ZA814606B (en) 1980-07-17 1981-07-07 New benzisoselenazolones process for producing the same and pharmaceutical preparations containing the same

Country Status (8)

Country Link
US (1) US4418069A (de)
EP (2) EP0044453B1 (de)
JP (1) JPS5767568A (de)
CA (1) CA1168243A (de)
DE (1) DE3027075A1 (de)
DK (1) DK150903C (de)
IE (1) IE51344B1 (de)
ZA (1) ZA814606B (de)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3027075A1 (de) 1980-07-17 1982-02-18 A. Nattermann & Cie GmbH, 5000 Köln Benzisoselenazolone, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische praeparate
DE3226284A1 (de) * 1982-07-14 1984-01-19 A. Nattermann & Cie GmbH, 5000 Köln Neue benzisoselenazolone, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische praeparate
DE3226286A1 (de) * 1982-07-14 1984-01-19 A. Nattermann & Cie GmbH, 5000 Köln Cycloalkylderivate von benzisoselenazolonen, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische praeparate
DE3407511A1 (de) * 1984-03-01 1985-09-05 A. Nattermann & Cie GmbH, 5000 Köln Benzisoselenazolthione, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische praeparate
EP0165534B1 (de) * 1984-06-22 1989-03-15 A. Nattermann & Cie. GmbH S-(Carbamoyl-phenylselenyl)-Derivate des Glutathions und von Aminomercaptocarbonsäuren, Verfahren zu ihrer Herstellung und diese enthaltende pharmazeutische Präparate
DE3443467A1 (de) * 1984-11-29 1986-05-28 A. Nattermann & Cie GmbH, 5000 Köln Mercaptanderivate, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische praeparate
DE3444135A1 (de) * 1984-12-04 1986-06-05 A. Nattermann & Cie GmbH, 5000 Köln Selenoxide, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische praeparate
EP0198277B1 (de) * 1985-04-12 1989-05-03 A. Nattermann & Cie. GmbH Diselenobis-benzoesäureamide primärer und sekundärer Amine, Verfahren zu ihrer Herstellung und diese enthaltende pharmazeutische Präparate
DE3670635D1 (de) * 1985-04-27 1990-05-31 Nattermann A & Cie Neue benzisoselenazolonyl-derivate, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische praeparate.
DE3718765A1 (de) * 1986-06-11 1987-12-17 Nippon Shinyaku Co Ltd Benzoesaeurederivate
DE3626554A1 (de) * 1986-08-06 1988-02-18 Nattermann A & Cie Diselenobis-benzoesaeureamide primaerer heterocyclischer amine, verfahren zur ihrer herstellung und diese enthaltende pharmazeutische praeparate
US4778814A (en) * 1987-03-18 1988-10-18 Ciba-Geigy Corporation Method of treating ocular allergy by topical application of a 2-substituted-1,2-benzisoselenazol-3(2H)-one
US4778815A (en) * 1987-03-18 1988-10-18 Ciba-Geigy Corporation Method of inhibiting cataracts by topical application of a 2-substituted 1,2-benzisoselenazol-3(2H)-one
DE3937169A1 (de) * 1989-11-08 1991-05-16 Nattermann A & Cie Benzylselenobenzamide von anilinen und benzylaminen
DE3937170A1 (de) * 1989-11-08 1991-05-16 Nattermann A & Cie Benzylselenobenzamide von aminopyridinen und picolylaminen
JP2553434B2 (ja) * 1992-04-28 1996-11-13 第一製薬株式会社 粒状製剤
US6335036B1 (en) 1993-10-27 2002-01-01 Daiichi Pharmaceutical Co., Ltd. Granular pharmaceutical preparation of ebselen
WO1996033712A1 (fr) * 1995-04-25 1996-10-31 Daiichi Pharmaceutical Co., Ltd. Remede pour lutter contre le syndrome de l'immunodeficience acquise
JP2000016935A (ja) * 1998-07-01 2000-01-18 Dai Ichi Seiyaku Co Ltd シクロオキシゲナーゼ阻害剤
CA2368484A1 (en) * 1999-03-31 2000-10-05 Daiichi Pharmaceutical Co., Ltd. Substrates for thioredoxin reductase
CN1166651C (zh) * 2001-06-08 2004-09-15 北京大学药学院 具有抗炎和抗肿瘤作用r-双或糖苯丙异硒唑取代化合物
US10058542B1 (en) 2014-09-12 2018-08-28 Thioredoxin Systems Ab Composition comprising selenazol or thiazolone derivatives and silver and method of treatment therewith

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR6429M (de) 1966-01-05 1968-11-04
CA1112164A (en) * 1977-08-02 1981-11-10 Joseph R. Levitt Therapeutic selenium compositions and the use thereof
DE3027074A1 (de) * 1980-07-17 1982-02-18 A. Nattermann & Cie GmbH, 5000 Köln Benzisoselenazolon enthaltende pharmazeutische praeparate und ihre verwendung
DE3027075A1 (de) 1980-07-17 1982-02-18 A. Nattermann & Cie GmbH, 5000 Köln Benzisoselenazolone, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische praeparate

Also Published As

Publication number Publication date
US4418069A (en) 1983-11-29
EP0044453B1 (de) 1984-04-11
JPS5767568A (en) 1982-04-24
IE811513L (en) 1982-01-17
JPH0238591B2 (de) 1990-08-31
DE3027075C2 (de) 1989-05-18
DE3027075A1 (de) 1982-02-18
EP0098934A1 (de) 1984-01-25
EP0044453A3 (en) 1982-03-31
CA1168243A (en) 1984-05-29
IE51344B1 (en) 1986-12-10
EP0044453A2 (de) 1982-01-27
DK150903C (da) 1988-01-25
EP0098934B1 (de) 1985-12-27
DK150903B (da) 1987-07-13
DK319281A (da) 1982-01-18

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