ZA813141B - New 1,4-dihydropyridine compounds having different substittuents in the 2-position and 6-position, their porduction, and their medicinal use - Google Patents

New 1,4-dihydropyridine compounds having different substittuents in the 2-position and 6-position, their porduction, and their medicinal use

Info

Publication number
ZA813141B
ZA813141B ZA00813141A ZA813141A ZA813141B ZA 813141 B ZA813141 B ZA 813141B ZA 00813141 A ZA00813141 A ZA 00813141A ZA 813141 A ZA813141 A ZA 813141A ZA 813141 B ZA813141 B ZA 813141B
Authority
ZA
South Africa
Prior art keywords
different
substittuents
porduction
new
medicinal use
Prior art date
Application number
ZA00813141A
Other languages
English (en)
Inventor
E Wehinger
H Meyer
F Bossert
S Kazda
K Stoepel
R Towart
W Vater
Original Assignee
Bayer Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ag filed Critical Bayer Ag
Publication of ZA813141B publication Critical patent/ZA813141B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/80—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D211/84—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
    • C07D211/90—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Vascular Medicine (AREA)
  • Hospice & Palliative Care (AREA)
  • Urology & Nephrology (AREA)
  • Psychiatry (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
ZA00813141A 1980-05-13 1981-05-12 New 1,4-dihydropyridine compounds having different substittuents in the 2-position and 6-position, their porduction, and their medicinal use ZA813141B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19803018259 DE3018259A1 (de) 1980-05-13 1980-05-13 1,4-dihydropyridine mit unterschiedlichen substituenten in 2- und 6-position, verfahren zu ihrer herstellung und ihre verwendung in arzneimitteln

Publications (1)

Publication Number Publication Date
ZA813141B true ZA813141B (en) 1982-04-28

Family

ID=6102290

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA00813141A ZA813141B (en) 1980-05-13 1981-05-12 New 1,4-dihydropyridine compounds having different substittuents in the 2-position and 6-position, their porduction, and their medicinal use

Country Status (17)

Country Link
EP (1) EP0039863B1 (el)
JP (1) JPS577468A (el)
AT (1) ATE5718T1 (el)
AU (1) AU541935B2 (el)
CA (2) CA1175438A (el)
DE (2) DE3018259A1 (el)
DK (1) DK210281A (el)
ES (2) ES502132A0 (el)
FI (1) FI811437L (el)
GR (1) GR74910B (el)
HU (1) HU184434B (el)
IE (1) IE51267B1 (el)
IL (1) IL62841A (el)
NO (1) NO811424L (el)
PH (1) PH18747A (el)
PT (1) PT72964B (el)
ZA (1) ZA813141B (el)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3207982A1 (de) * 1982-03-05 1983-09-08 Bayer Ag, 5090 Leverkusen Neue 1,4-dihydropyridine, verfahren zu ihrer herstellung und ihrer verwendung in arzneimitteln
DE3208628A1 (de) * 1982-03-10 1983-09-22 Bayer Ag, 5090 Leverkusen Neue verbindungen, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel
US4414213A (en) * 1982-03-22 1983-11-08 Mead Johnson & Company Dihydropyridyl cyclic imidate esters and their pharmaceutical use
JPS58208271A (ja) * 1982-04-30 1983-12-03 Kyowa Hakko Kogyo Co Ltd １，４−ジヒドロピリジン誘導体
JPS6094963A (ja) * 1983-10-31 1985-05-28 Teijin Ltd １，４−ジヒドロピリジン−３，５−ジカルボン酸ジエステル誘導体及びその製造法
NZ212895A (en) * 1984-08-22 1988-07-28 Glaxo Spa 1,4-dihydropyridine derivatives and pharmaceutical compositions
DE3447169A1 (de) * 1984-12-22 1986-07-03 Bayer Ag, 5090 Leverkusen Optisch aktive nitrodihydropyridine, verfahren zur herstellung und ihre verwendung in arzneimitteln
JPS625958A (ja) * 1985-07-03 1987-01-12 Suntory Ltd １，４−ジヒドロピリジン誘導体、その製造法および循環系疾患治療剤
US4761420A (en) * 1986-06-13 1988-08-02 Laboratoires Syntex S.A. Antihypertensive dihydropyridine derivatives
US5075324A (en) * 1986-12-24 1991-12-24 Boehringer Biochemia Robin S.P.A. Aralkyl-1,4-dihydropyridines, a method for their preparation and pharmaceutical composition containing them
US5158963A (en) * 1989-08-02 1992-10-27 Kaken Pharmaceutical Co., Ltd. 1-4-dihydropyridine derivative, process for preparing the same and pharmaceutical composition containing the same
WO1991009847A1 (fr) * 1989-12-29 1991-07-11 Kaken Pharmaceutical Co., Ltd. Derive d'ethynylphenyle, production de ce derive et medicament de traitement des maladies des organes du systeme circulatoire contenant ce derive comme ingredient actif
DE59410255D1 (de) * 1993-12-10 2003-04-17 Bayer Ag Phenyl-substituierte 1,4-Dihydropyridine mit cerebraler Aktivität

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1792764C3 (de) * 1967-03-20 1981-04-23 Bayer Ag, 5090 Leverkusen Coronarmittel
GB1430961A (en) * 1972-01-22 1976-04-07 Yamanouchi Pharma Co Ltd 1-substituted-1,4-dihyddrypyridine derivatives
DE2508181A1 (de) * 1975-02-26 1976-09-09 Bayer Ag 1,4-dihydropyridincarbonsaeurearal- kylester, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel
GB1591089A (en) * 1976-12-17 1981-06-10 Fujisawa Pharmaceutical Co 1,4-dihydropyridine derivatives and process for preparation thereof
SE7910521L (sv) * 1979-12-20 1981-06-21 Haessle Ab Nya 2-metyl-6-substituerade-4-(2,3-disubstituerad fenyl)-1,4-dihydropyridin-3,5-diestrar med hypotesiva egenskaper, samt forfarande for deras framstellning, och farmaceutiska beredningar innehallande desamma

Also Published As

Publication number Publication date
GR74910B (el) 1984-07-12
PT72964A (en) 1981-06-01
EP0039863A1 (de) 1981-11-18
ES8300093A1 (es) 1982-10-01
EP0039863B1 (de) 1983-12-28
CA1175438A (en) 1984-10-02
ATE5718T1 (de) 1984-01-15
IL62841A0 (en) 1981-07-31
IE51267B1 (en) 1986-11-26
FI811437L (fi) 1981-11-14
CA1185182A (en) 1985-04-09
ES8304082A1 (es) 1983-02-16
PT72964B (en) 1982-06-25
NO811424L (no) 1981-11-16
IE811061L (en) 1981-11-13
AU541935B2 (en) 1985-01-31
ES512592A0 (es) 1983-02-16
DE3018259A1 (de) 1981-11-19
DK210281A (da) 1981-11-14
HU184434B (en) 1984-08-28
AU7047381A (en) 1981-11-19
DE3161760D1 (en) 1984-02-02
PH18747A (en) 1985-09-19
ES502132A0 (es) 1982-10-01
JPS577468A (en) 1982-01-14
IL62841A (en) 1984-11-30

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