ZA80578B - New 2-amino-8-cyclopropyl-5-oxo-5,8-dihydro-pyrido((2,3-d))pyrimidine-6-carboxylic acid compounds,their production and their medicinal use - Google Patents
New 2-amino-8-cyclopropyl-5-oxo-5,8-dihydro-pyrido((2,3-d))pyrimidine-6-carboxylic acid compounds,their production and their medicinal useInfo
- Publication number
- ZA80578B ZA80578B ZA00800578A ZA80578A ZA80578B ZA 80578 B ZA80578 B ZA 80578B ZA 00800578 A ZA00800578 A ZA 00800578A ZA 80578 A ZA80578 A ZA 80578A ZA 80578 B ZA80578 B ZA 80578B
- Authority
- ZA
- South Africa
- Prior art keywords
- cyclopropyl
- pyrimidine
- oxo
- amino
- acid compounds
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/32—One oxygen, sulfur or nitrogen atom
- C07D239/42—One nitrogen atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
- C07D239/47—One nitrogen atom and one oxygen or sulfur atom, e.g. cytosine
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Communicable Diseases (AREA)
- Pharmacology & Pharmacy (AREA)
- Oncology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Fodder In General (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19792903850 DE2903850A1 (de) | 1979-02-01 | 1979-02-01 | 2-amino-8-cyclopropyl-5-oxo-5,8- dihydro-pyrido eckige klammer auf 2,3-d eckige klammer zu -pyrimidin-6-carnonsaeuren, verfahren zu ihrer herstellung sowie ihrer verwendung als antibakterielle mittel |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA80578B true ZA80578B (en) | 1981-01-28 |
Family
ID=6061940
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA00800578A ZA80578B (en) | 1979-02-01 | 1980-01-31 | New 2-amino-8-cyclopropyl-5-oxo-5,8-dihydro-pyrido((2,3-d))pyrimidine-6-carboxylic acid compounds,their production and their medicinal use |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US4556709A (xx) |
| EP (1) | EP0014390B1 (xx) |
| JP (2) | JPS5817758B2 (xx) |
| AT (1) | ATE647T1 (xx) |
| AU (1) | AU537475B2 (xx) |
| CA (1) | CA1142923A (xx) |
| DE (2) | DE2903850A1 (xx) |
| DK (1) | DK152499C (xx) |
| ES (1) | ES488186A1 (xx) |
| FI (1) | FI68823C (xx) |
| IL (1) | IL59253A (xx) |
| ZA (1) | ZA80578B (xx) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3033157A1 (de) * | 1980-09-03 | 1982-04-01 | Bayer Ag, 5090 Leverkusen | 7-amino-1-cyclopropyl-4-oxo-1,4-dihydro-naphthyridin-3-carbonsaeuren, verfahren zu ihrer herstellung sowie diese enthaltende antibakterielle mittel |
| US4670444B1 (en) * | 1980-09-03 | 1999-02-09 | Bayer Ag | and-naphthyridine-3-carboxylic acids and antibacte7-amino-1-cyclopropyl-4-oxo-1,4-dihydro-quinoline-rial agents containing these compounds |
| IT1200470B (it) * | 1985-05-10 | 1989-01-18 | Schering Spa | Composti ad attivita' antibatterica,loro preparazione e composizioni farmaceutiche relative |
| DE3786256T2 (de) * | 1986-12-02 | 1993-10-07 | British Tech Group | Antifolat-mittel. |
| TW200800983A (en) | 2005-09-14 | 2008-01-01 | Janssen Pharmaceutica Nv | 5-oxo-5,8-dihydro-pyrido-pyrimidines as inhibitors of C-FMS kinase |
| US7642270B2 (en) | 2005-09-14 | 2010-01-05 | Janssen Pharmaceutica N.V. | 5-oxo-5,8-dihydro-pyrido-pyrimidine as inhibitors of c-fms kinase |
| CN102098918A (zh) * | 2008-05-13 | 2011-06-15 | 帕纳德制药公司 | 用于治疗癌症和神经退行性疾病的生物活性化合物 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS4837279B1 (xx) * | 1970-08-29 | 1973-11-09 | ||
| US3673184A (en) * | 1970-09-02 | 1972-06-27 | Dainippon Pharmaceutical Co | Certain 2-substituted-5,8-dihydro-5-oxopyrido{8 2,3-d{9 pyrimidine-6-carboxylic acid derivatives |
| FR2194420B1 (xx) * | 1972-08-02 | 1975-10-17 | Bellon Labor Sa Roger | |
| JPS5336478B2 (xx) * | 1972-08-14 | 1978-10-03 | ||
| GB1451912A (en) * | 1972-08-14 | 1976-10-06 | Dainippon Pharmaceutical Co | 2-1-piperazino-5-oxopyrido-2,3-d-pyridine-6-carboxylic acids their preparation and pharmaceutical compositions thereof |
| US4017622A (en) * | 1972-12-18 | 1977-04-12 | Dainippon Pharmaceutical Co., Ltd. | Piperazine derivatives |
| US3992380A (en) * | 1975-03-03 | 1976-11-16 | Sterling Drug Inc. | 5,8-Dihydro-5-oxo-2-(4-or 3-pyridinyl)pyrido[2,3-d]pyrimidine-6-carboxylic acids and esters |
| JPS5312889A (en) * | 1976-07-22 | 1978-02-04 | Dainippon Pharmaceut Co Ltd | P-aminobenzylpiperazine dervatives |
-
1979
- 1979-02-01 DE DE19792903850 patent/DE2903850A1/de not_active Withdrawn
-
1980
- 1980-01-24 AT AT80100363T patent/ATE647T1/de not_active IP Right Cessation
- 1980-01-24 EP EP80100363A patent/EP0014390B1/de not_active Expired
- 1980-01-24 DE DE8080100363T patent/DE3060162D1/de not_active Expired
- 1980-01-29 IL IL59253A patent/IL59253A/xx unknown
- 1980-01-29 AU AU55023/80A patent/AU537475B2/en not_active Ceased
- 1980-01-30 CA CA000344716A patent/CA1142923A/en not_active Expired
- 1980-01-30 JP JP55008893A patent/JPS5817758B2/ja not_active Expired
- 1980-01-30 FI FI800266A patent/FI68823C/fi not_active IP Right Cessation
- 1980-01-31 ZA ZA00800578A patent/ZA80578B/xx unknown
- 1980-01-31 DK DK041880A patent/DK152499C/da active
- 1980-02-01 ES ES488186A patent/ES488186A1/es not_active Expired
-
1982
- 1982-07-26 US US06/401,684 patent/US4556709A/en not_active Expired - Fee Related
- 1982-10-15 JP JP57180052A patent/JPS5877816A/ja active Granted
Also Published As
| Publication number | Publication date |
|---|---|
| DK152499B (da) | 1988-03-07 |
| IL59253A0 (en) | 1980-05-30 |
| EP0014390A1 (de) | 1980-08-20 |
| DK41880A (da) | 1980-08-02 |
| ES488186A1 (es) | 1980-09-16 |
| FI68823B (fi) | 1985-07-31 |
| EP0014390B1 (de) | 1982-02-03 |
| FI800266A (fi) | 1980-08-02 |
| DE3060162D1 (en) | 1982-03-11 |
| US4556709A (en) | 1985-12-03 |
| FI68823C (fi) | 1985-11-11 |
| AU537475B2 (en) | 1984-06-28 |
| AU5502380A (en) | 1980-08-07 |
| JPS5877816A (ja) | 1983-05-11 |
| JPS5817758B2 (ja) | 1983-04-09 |
| ATE647T1 (de) | 1982-02-15 |
| JPS55104281A (en) | 1980-08-09 |
| CA1142923A (en) | 1983-03-15 |
| DE2903850A1 (de) | 1980-08-07 |
| DK152499C (da) | 1988-07-25 |
| IL59253A (en) | 1983-07-31 |
| JPS6246523B2 (xx) | 1987-10-02 |
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