DK152499C - Analogifremgangsmaade til fremstilling af 2-amino-8-cyclopropyl-5-oxo-5,8-dihydro-pyridooe2,3-daapyrimidin-6-carboxylsyrer - Google Patents

Analogifremgangsmaade til fremstilling af 2-amino-8-cyclopropyl-5-oxo-5,8-dihydro-pyridooe2,3-daapyrimidin-6-carboxylsyrer

Info

Publication number
DK152499C
DK152499C DK041880A DK41880A DK152499C DK 152499 C DK152499 C DK 152499C DK 041880 A DK041880 A DK 041880A DK 41880 A DK41880 A DK 41880A DK 152499 C DK152499 C DK 152499C
Authority
DK
Denmark
Prior art keywords
cyclopropyl
oxo
amino
preparation
pyridooe2
Prior art date
Application number
DK041880A
Other languages
English (en)
Other versions
DK41880A (da
DK152499B (da
Inventor
Klaus Grohe
Hans-Joachim Zeiler
Karl Georg Metzger
Original Assignee
Bayer Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ag filed Critical Bayer Ag
Publication of DK41880A publication Critical patent/DK41880A/da
Publication of DK152499B publication Critical patent/DK152499B/da
Application granted granted Critical
Publication of DK152499C publication Critical patent/DK152499C/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/32One oxygen, sulfur or nitrogen atom
    • C07D239/42One nitrogen atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/47One nitrogen atom and one oxygen or sulfur atom, e.g. cytosine
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Fodder In General (AREA)
DK041880A 1979-02-01 1980-01-31 Analogifremgangsmaade til fremstilling af 2-amino-8-cyclopropyl-5-oxo-5,8-dihydro-pyridooe2,3-daapyrimidin-6-carboxylsyrer DK152499C (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE2903850 1979-02-01
DE19792903850 DE2903850A1 (de) 1979-02-01 1979-02-01 2-amino-8-cyclopropyl-5-oxo-5,8- dihydro-pyrido eckige klammer auf 2,3-d eckige klammer zu -pyrimidin-6-carnonsaeuren, verfahren zu ihrer herstellung sowie ihrer verwendung als antibakterielle mittel

Publications (3)

Publication Number Publication Date
DK41880A DK41880A (da) 1980-08-02
DK152499B DK152499B (da) 1988-03-07
DK152499C true DK152499C (da) 1988-07-25

Family

ID=6061940

Family Applications (1)

Application Number Title Priority Date Filing Date
DK041880A DK152499C (da) 1979-02-01 1980-01-31 Analogifremgangsmaade til fremstilling af 2-amino-8-cyclopropyl-5-oxo-5,8-dihydro-pyridooe2,3-daapyrimidin-6-carboxylsyrer

Country Status (12)

Country Link
US (1) US4556709A (da)
EP (1) EP0014390B1 (da)
JP (2) JPS5817758B2 (da)
AT (1) ATE647T1 (da)
AU (1) AU537475B2 (da)
CA (1) CA1142923A (da)
DE (2) DE2903850A1 (da)
DK (1) DK152499C (da)
ES (1) ES488186A1 (da)
FI (1) FI68823C (da)
IL (1) IL59253A (da)
ZA (1) ZA80578B (da)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4670444B1 (en) * 1980-09-03 1999-02-09 Bayer Ag and-naphthyridine-3-carboxylic acids and antibacte7-amino-1-cyclopropyl-4-oxo-1,4-dihydro-quinoline-rial agents containing these compounds
DE3033157A1 (de) * 1980-09-03 1982-04-01 Bayer Ag, 5090 Leverkusen 7-amino-1-cyclopropyl-4-oxo-1,4-dihydro-naphthyridin-3-carbonsaeuren, verfahren zu ihrer herstellung sowie diese enthaltende antibakterielle mittel
IT1200470B (it) * 1985-05-10 1989-01-18 Schering Spa Composti ad attivita' antibatterica,loro preparazione e composizioni farmaceutiche relative
GB2204867B (en) * 1986-12-02 1991-05-29 Malcolm Francis Graham Stevens Antifoliate pyrimidine compounds
TW200800983A (en) * 2005-09-14 2008-01-01 Janssen Pharmaceutica Nv 5-oxo-5,8-dihydro-pyrido-pyrimidines as inhibitors of C-FMS kinase
US7642270B2 (en) 2005-09-14 2010-01-05 Janssen Pharmaceutica N.V. 5-oxo-5,8-dihydro-pyrido-pyrimidine as inhibitors of c-fms kinase
EP2273882A4 (en) * 2008-05-13 2011-07-13 Poniard Pharmaceuticals Inc BIOACTIVE COMPOUNDS FOR THE TREATMENT OF CANCER AND NEURODEEGENERATIVE DISEASES

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS4837279B1 (da) * 1970-08-29 1973-11-09
US3673184A (en) * 1970-09-02 1972-06-27 Dainippon Pharmaceutical Co Certain 2-substituted-5,8-dihydro-5-oxopyrido{8 2,3-d{9 pyrimidine-6-carboxylic acid derivatives
FR2194420B1 (da) * 1972-08-02 1975-10-17 Bellon Labor Sa Roger
JPS5336478B2 (da) * 1972-08-14 1978-10-03
GB1451912A (en) * 1972-08-14 1976-10-06 Dainippon Pharmaceutical Co 2-1-piperazino-5-oxopyrido-2,3-d-pyridine-6-carboxylic acids their preparation and pharmaceutical compositions thereof
US4017622A (en) * 1972-12-18 1977-04-12 Dainippon Pharmaceutical Co., Ltd. Piperazine derivatives
US3992380A (en) * 1975-03-03 1976-11-16 Sterling Drug Inc. 5,8-Dihydro-5-oxo-2-(4-or 3-pyridinyl)pyrido[2,3-d]pyrimidine-6-carboxylic acids and esters
JPS5312889A (en) * 1976-07-22 1978-02-04 Dainippon Pharmaceut Co Ltd P-aminobenzylpiperazine dervatives

Also Published As

Publication number Publication date
US4556709A (en) 1985-12-03
DK41880A (da) 1980-08-02
AU5502380A (en) 1980-08-07
CA1142923A (en) 1983-03-15
DK152499B (da) 1988-03-07
EP0014390A1 (de) 1980-08-20
ZA80578B (en) 1981-01-28
EP0014390B1 (de) 1982-02-03
JPS5877816A (ja) 1983-05-11
IL59253A (en) 1983-07-31
FI800266A (fi) 1980-08-02
JPS55104281A (en) 1980-08-09
FI68823B (fi) 1985-07-31
JPS5817758B2 (ja) 1983-04-09
IL59253A0 (en) 1980-05-30
DE2903850A1 (de) 1980-08-07
DE3060162D1 (en) 1982-03-11
ES488186A1 (es) 1980-09-16
FI68823C (fi) 1985-11-11
AU537475B2 (en) 1984-06-28
JPS6246523B2 (da) 1987-10-02
ATE647T1 (de) 1982-02-15

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