ZA802524B - Hybrid cell line for producing monoclonal antibody to human helper t cells,antibody,and methods - Google Patents

Hybrid cell line for producing monoclonal antibody to human helper t cells,antibody,and methods

Info

Publication number
ZA802524B
ZA802524B ZA00802524A ZA802524A ZA802524B ZA 802524 B ZA802524 B ZA 802524B ZA 00802524 A ZA00802524 A ZA 00802524A ZA 802524 A ZA802524 A ZA 802524A ZA 802524 B ZA802524 B ZA 802524B
Authority
ZA
South Africa
Prior art keywords
antibody
cells
monoclonal antibody
cell line
hybrid cell
Prior art date
Application number
ZA00802524A
Other languages
English (en)
Inventor
P Kung
G Goldstein
Original Assignee
Ortho Pharma Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=21871570&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ZA802524(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Ortho Pharma Corp filed Critical Ortho Pharma Corp
Publication of ZA802524B publication Critical patent/ZA802524B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
    • C07K16/3061—Blood cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/2812—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against CD4
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/966—Chemistry: molecular biology and microbiology involving an enzyme system with high turnover rate or complement magnified assay, e.g. multi-enzyme systems
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/808—Materials and products related to genetic engineering or hybrid or fused cell technology, e.g. hybridoma, monoclonal products

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Cell Biology (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Hematology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
  • Hybrid Cells (AREA)
ZA00802524A 1979-04-26 1980-04-25 Hybrid cell line for producing monoclonal antibody to human helper t cells,antibody,and methods ZA802524B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/033,639 US4381295A (en) 1979-04-26 1979-04-26 Monoclonal antibody to human helper T cells and methods of preparing same

Publications (1)

Publication Number Publication Date
ZA802524B true ZA802524B (en) 1981-12-30

Family

ID=21871570

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA00802524A ZA802524B (en) 1979-04-26 1980-04-25 Hybrid cell line for producing monoclonal antibody to human helper t cells,antibody,and methods

Country Status (22)

Country Link
US (1) US4381295A (pt)
EP (1) EP0018794B1 (pt)
JP (2) JPS55145616A (pt)
AT (1) ATE14454T1 (pt)
AU (1) AU544792B2 (pt)
CA (1) CA1170592A (pt)
DE (2) DE3070896D1 (pt)
DK (1) DK154087C (pt)
ES (1) ES490943A0 (pt)
FI (1) FI75363C (pt)
GR (1) GR67298B (pt)
HK (1) HK23786A (pt)
IE (1) IE50459B1 (pt)
IL (1) IL59919A (pt)
MY (1) MY8600513A (pt)
NO (1) NO159883C (pt)
NZ (1) NZ193470A (pt)
PH (1) PH16656A (pt)
PT (1) PT71148B (pt)
SG (1) SG6586G (pt)
YU (1) YU44957B (pt)
ZA (1) ZA802524B (pt)

Families Citing this family (43)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4381292A (en) * 1980-11-14 1983-04-26 The Board Of Trustees Of The Leland Stanford Jr. University Anti-human T-lymphocyte monoclonal antibody
US4824432A (en) * 1981-03-24 1989-04-25 S.V.S. Laboratories, Inc. Method for treating AIDS and other immune deficiencies and immune disorders
US4474893A (en) * 1981-07-01 1984-10-02 The University of Texas System Cancer Center Recombinant monoclonal antibodies
USRE32011E (en) * 1981-12-14 1985-10-22 Scripps Clinic And Research Foundation Ultrapurification of factor VIII using monoclonal antibodies
US4511662A (en) * 1982-06-18 1985-04-16 Bio-Rad Laboratories, Inc. Simultaneous assay for T and B lymphocyte populations and subpopulations
US4443427A (en) * 1982-06-21 1984-04-17 Sidney Farber Cancer Institute, Inc. Monoclonal antibody
US4582790A (en) * 1983-02-15 1986-04-15 Wisconsin Alumni Research Foundation Monoclonal antibody to angiotension-converting enzyme and methods of preparing and using same
US4550086A (en) * 1983-02-16 1985-10-29 Dana-Farber Cancer Institute, Inc. Monoclonal antibodies that recognize human T cells
US4677056A (en) * 1983-08-18 1987-06-30 Sloan-Kettering Institute For Cancer Research Monoclonal antibody subsetting human helper and killer T-cells and method
USRE35277E (en) * 1983-09-11 1996-06-18 Yeda Research And Development Co. Ltd. Cell membrane proteins, compositions containing them and procedure for their preparation
IL69686A (en) * 1983-09-11 1988-03-31 Yeda Res & Dev Compositions containing cell membrane proteins and process for their preparation
US4645738A (en) * 1983-09-30 1987-02-24 Memorial Sloan-Kettering Institute Cancer Center Method for differential diagnosis of T cell leukemias using monoclonal antibodies
JPS60231699A (ja) * 1983-11-09 1985-11-18 Aichiken 正常及び悪性ヒト造血器細胞に対するモノクローナル抗体
US4469630A (en) * 1983-11-25 1984-09-04 J. T. Baker Chemical Co. Purification of monoclonal antibodies
DE3482649D1 (de) 1983-12-16 1990-08-09 Denis M Callewaert Stellenselektiver plasminogenaktivator und verfahren zu seiner herstellung und verwendung.
US5130144B1 (en) * 1984-02-06 1995-08-15 Univ Johns Hopkins Human stem cells and monoclonal antibodies
US4965204A (en) * 1984-02-06 1990-10-23 The Johns Hopkins University Human stem cells and monoclonal antibodies
US4604235A (en) * 1984-05-23 1986-08-05 J. T. Baker Chemical Company Purification of monoclonal antibodies
FR2570278B1 (fr) * 1984-09-14 1987-02-13 Pasteur Institut Compositions et procede pour proteger les lymphocytes t contre l'agent etiologique des lymphadenopathies et du syndrome d'immunodepression acquise
EP0335426B1 (fr) * 1984-09-14 1991-07-03 Institut Pasteur Composition et procédé pour protéger les lymphocytes T contre l'agent étiologique des lymphadénopathies et du syndrome d'immunisation acquise
US4695459A (en) * 1984-12-26 1987-09-22 The Board Of Trustees Of Leland Stanford Junior University Method of treating autoimmune diseases that are mediated by Leu3/CD4 phenotype T cells
US4661446A (en) * 1985-02-19 1987-04-28 Dana-Farber Cancer Institute, Inc. Monoclonal antibodies and method of immunizing therewith
US5776093A (en) * 1985-07-05 1998-07-07 Immunomedics, Inc. Method for imaging and treating organs and tissues
DE3541033A1 (de) * 1985-11-19 1987-05-21 Boehringer Mannheim Gmbh Verfahren zur quantifizierung von zellpopulationen bzw. subpopulationen sowie hierfuer geeignetes reagenz
GB8608068D0 (en) * 1986-04-02 1986-05-08 Cobbold S P Monoclonal antibodies
CA1296622C (en) * 1986-08-12 1992-03-03 Jeffrey E. Anderson Method and apparatus for automated assessment of the immunoregulatory status of the mononuclear leukocyte immune system
US5601819A (en) * 1988-08-11 1997-02-11 The General Hospital Corporation Bispecific antibodies for selective immune regulation and for selective immune cell binding
US5068178A (en) * 1988-12-06 1991-11-26 Genetic Systems Corporation Method of enhancing direct immunofluorescence staining of cells
US7037496B2 (en) * 1989-12-27 2006-05-02 Centocor, Inc. Chimeric immunoglobulin for CD4 receptors
JPH0424999U (pt) * 1990-06-26 1992-02-28
GB9021677D0 (en) * 1990-10-05 1990-11-21 Xaar Ltd Method of testing multi-channel array pulsed droplet deposition apparatus
WO1992009305A1 (en) * 1990-11-27 1992-06-11 Biogen, Inc. Anti cd-4 antibodies blocking hiv-induced syncytia
US5747265A (en) * 1992-10-30 1998-05-05 T Cell Diagnostics, Inc. Method for measuring the amount of a cell-associated molecule
GB2294267B (en) * 1993-06-03 1996-11-20 Therapeutic Antibodies Inc Anti-TNFalpha Fab fragments derived from polyclonal IgG antibodies
US5961976A (en) * 1996-06-03 1999-10-05 United Biomedical, Inc. Antibodies against a host cell antigen complex for pre- and post-exposure protection from infection by HIV
EP0963377B1 (en) 1996-08-30 2009-03-04 Human Genome Sciences, Inc. Interleukin-19
CA2310805A1 (en) 1997-11-24 1999-06-03 Johnson T. Wong Methods for treatment of hiv or other infections using a t cell or viral activator and anti-retroviral combination therapy
US6790796B2 (en) 2001-10-05 2004-09-14 Albany International Corp. Nonwovens forming or conveying fabrics with enhanced surface roughness and texture
US20080279848A1 (en) * 2006-03-16 2008-11-13 Genentech, Inc. Methods of treating lupus using CD4 antibodies
US20070218062A1 (en) * 2006-03-16 2007-09-20 Genentech, Inc. Methods of treating lupus using CD4 antibodies
US20100021460A1 (en) * 2008-07-15 2010-01-28 Genentech, Inc. Methods of Treating Autoimmune Diseases Using CD4 Antibodies
AU2014406462A1 (en) 2014-09-16 2017-04-06 Ubi Ip Holdings Treatment and functional cure of HIV infection by monoclonal antibodies to CD4 mediating competitive HIV entry inhibition
JP2019534891A (ja) 2016-08-13 2019-12-05 ユナイテッド バイオファーマ、インク．Ｕｎｉｔｅｄ Ｂｉｏｐｈａｒｍａ， Ｉｎｃ． Ｈａａｒｔ安定化患者におけるｃｄ４に対する抗体によるｈｉｖ感染症の処置および持続的ウイルス学的寛解

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4196265A (en) * 1977-06-15 1980-04-01 The Wistar Institute Method of producing antibodies

Also Published As

Publication number Publication date
IE50459B1 (en) 1986-04-30
FI75363C (fi) 1988-06-09
PH16656A (en) 1983-12-09
YU44957B (en) 1991-06-30
JPH0198477A (ja) 1989-04-17
EP0018794A2 (en) 1980-11-12
YU114880A (en) 1985-04-30
DE3070896D1 (en) 1985-08-29
DK180580A (da) 1980-10-27
ATE14454T1 (de) 1985-08-15
GR67298B (pt) 1981-06-29
ES8105151A1 (es) 1981-05-16
IL59919A0 (en) 1980-06-30
EP0018794A3 (en) 1981-01-07
JPS55145616A (en) 1980-11-13
DK154087C (da) 1989-02-27
JPS6362519B2 (pt) 1988-12-02
HK23786A (en) 1986-04-11
IE800839L (en) 1980-10-26
NO801216L (no) 1980-10-27
FI75363B (fi) 1988-02-29
ES490943A0 (es) 1981-05-16
NZ193470A (en) 1984-07-06
NO159883B (no) 1988-11-07
US4381295A (en) 1983-04-26
PT71148A (en) 1980-05-01
JPH0159867B2 (pt) 1989-12-20
MY8600513A (en) 1986-12-31
IL59919A (en) 1983-12-30
AU5775880A (en) 1980-10-30
PT71148B (en) 1981-08-11
NO159883C (no) 1989-02-15
EP0018794B1 (en) 1985-07-24
AU544792B2 (en) 1985-06-13
DE18794T1 (de) 1984-07-19
DK154087B (da) 1988-10-10
FI801343A (fi) 1980-10-27
SG6586G (en) 1986-08-01
CA1170592A (en) 1984-07-10

Similar Documents

Publication Publication Date Title
ZA802524B (en) Hybrid cell line for producing monoclonal antibody to human helper t cells,antibody,and methods
AU545223B2 (en) Hybrid cell line for producing monoclonal antibody
DE3170352D1 (en) Hybrid cell line for producing monoclonal antibody to a human t cell antigen, antibody, and methods
AU545182B2 (en) Hybrid cell hire for producing monoclonal antibody
JPS6463376A (en) Hybridmer
ZA807564B (en) Hybird cell line for producing monoclonal antibody to a human thymocyte antigen,antibody,and methods